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Journal of Environmental Protection 2014年第3期5卷 181-192页

作者： emily Amanda caffrey Mary Elizabeth Leonard Jonathan Bamberger Napier Delvan Reed Neville Kathryn Ann Higley Department of Nuclear Engineering and Radiation Health Physics Oregon State University Corvallis USA.

The importance of radioecology to the discussion of radioactive contamination is discussed here. This paper discusses the history of radioecology, alongside the most recent developments in the science. It describes the need for more environmental data, and explains where the gaps in current knowledge lie. The calculation of radiation dose to wildlife along with the complications in performing such calculations is discussed. The paper also tackles the difficult question of the implications of radioecology on nuclear waste management and site decommissioning policies. From the beginnings of the science to today, radioecology is poised to be an important field of study as humans continue to rely on ionizing radiation to improve their lives.

关键词： Radioecology Wildlife Dose Calculations Nuclear Waste Disposal Environmental Protection

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Low melting point MCP-69, MCP-96, MCP-137, and MCP-200 alloys for radiation protection in radiological and therapeutic processes

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Radiation Medicine and Protection 2022年第4期3卷 175-182页

作者： Michael W.Perrigin Kendall A.Williams Brandon K.Wright Malaika Maqbool emily caffrey Remo George Ghafar Ali Muhammad Maqbool Health Physics Program Department of Clinical&Diagnostic SciencesThe University of Alabama at BirminghamBirminghamAL 35294USA Nuclear Medicine and Molecular Imaging Sciences Program Department of Clinical&Diagnostic SciencesThe University of Alabama at BirminghamBirminghamAL 35294USA iomedical Sciences Program Department of Clinical&Diagnostic SciencesThe University of Alabama at BirminghamBirminghamAL 35294USA Nanomaterials Research Group Physics DivisionPINSTECHIslamabadPakistan

Objective To evaluate the low melting-point MCP-69,MCP-96,MCP-137,and MCP-200 alloys,and characterize them for their potential to protect from the harms associated with radiation and eliminate radiation hazards during radiological procedures and treatment of *** The Klein-Nishina formula was used to calculate the electronic and atomic cross-sections of these alloys using photon beams with energies 4,6,9,12,and 18*** transfer coefficients,Compton mass attenuation coefficient,mass-energy transfer coefficient,and recoil energy of electrons in the specific photon energies of 4–18MeV were *** alloys'effective charge number and the photon energy were key factors in determining the properties found by utilizing the Klein-Nishina formula and Compton *** The cross sections and energy transfer coefficients increased with the increasing effective charge number Z of the alloys and decreased as the photon energy *** Compton recoil of the ejected electrons was observed to have a direct relationship with photon energy,but mass-energy transfer decreased with increasing photon *** alloys can replace the toxic lead for environmentally cleaned radiation *** These calculations and characteristics of the MCP alloys can help further determine their viability as materials for radiation shielding,their use in safe cancer diagnosis,treatment,and environmental hazards protection.

关键词： MCP alloys Klein-Nishina formula Cross-sections Radiation shielding Safe cancer diagnosis and treatment

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Toward three-dimensional in vitro models to study neurovascular unit functions in health and disease

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Neural Regeneration Research 2021年第11期16卷 2132-2140页

作者： Tara M.caffrey emily B.Button Jerome Robert Djavad Mowafaghian Center for Brain Health University of British ColumbiaVancouverBCCanada Department of Pathology University of British ColumbiaVancouverBCCanada Institute of Clinical Chemistry University Hospital of ZurichZurichSwitzerland

The high metabolic demands of the brain require an efficient vascular system to be coupled with neural activity to supply adequate nutrients and *** supply is coordinated by the action of neurons,glial and vascular cells,known collectively as the neurovascular unit,which temporally and spatially regulate local cerebral blood flow through a process known as neurovascular *** many neurodegenerative diseases,changes in functions of the neurovascular unit not only impair neurovascular coupling but also permeability of the blood-brain barrier,cerebral blood flow and clearance of waste from the *** order to study disease mechanisms,we need improved physiologicallyrelevant human models of the neurovascular *** towards modeling the cellular complexity of the neurovascular unit in vitro have been made using stem-cell derived organoids and more recently,vascularized organoids,enabling intricate studies of non-cell autonomous *** and design innovations in microfluidic devices and tissue engineering are progressing our ability to interrogate the *** advanced models are being used to gain a better understanding of neurodegenerative disease processes and potential *** innovation is required to build more physiologically-relevant models of the neurovascular unit encompassing both the cellular complexity and designed features to interrogate neurovascular unit functionality.

关键词： Alzheimer’s disease cerebrovasculature in vitro model neurodegeneration neurovascular unit

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