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On the Jebsen-Birkhoff Theorem in a Born-Infeld Type Theory of Gravity

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Journal of High Energy Physics, Gravitation and Cosmology 2019年第4期5卷 1051-1056页

作者： Tiago de Oliveira Rosa Maria emilia Xavier Guimarã es Rocco Pascale Neto Joaquim Lopes Neto Instituto Federal Goiano Campus Urutaí Rodovia Geraldo Silva Nascimento Urutaí Brazil Instituto de Física Universidade Federal Fluminense Niterói Brazil Instituto de Física Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil

In this paper we work with a special theory of gravity|the Novello-Di Lorenci-Luciane (hereby called NDL theory) which extends the Feynman-Deser standard theoretical-fi eld approach to General Relativity. In the so-called NDL theory, matter interacts universally with gravity in accordance with the Weak Equivalence Principle, while gravitons have a nonlinear self-interaction. Our main aim in this work is to show that, though the NDL theory does not admit a Schwarzschild solution, the Jebsen-Birkhoff theorem is still valid in this framework.

关键词： Electrostatic Trapping Bootstrap Current Mitigation Peeling-Ballooning Mode

Impact of Droughts on Cedrus atlantica Forests Dieback in the Auras （Algeria）

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Journal of Life Sciences 2012年第11期6卷 1262-1269页

作者： Dalila Kherchouche Mahdi Kalla emilia M. Gutierrez Said Attalah Madj i d B ouzghaia Department of Agronomy Sciences Institute of Veterinary and Agronomy Sciences The University Hadj Lakhdar Batna 05000 Algeria Department of Earth Sciences The University Hadj Lakhdar Batna 05000 Algeria Department of Ecology Faculty of Biology The University of Barcelona Barcelona 08028 Spain College of Agriculture and Life Sciences ABE Department The University of Arizona Tucson 85721 USA Forests Direction of Khenchela Khenchela 40000 Algeria

Cedar forests area in northeastern Algeria （Aures） is decreasing by the massive tree mortality. In some localities more than 95% of the trees have recently died （e.g. Boumerzoug in Belezma National Park）. Three reported episodes of massive tree mortality in 1880, 1980, and 2000 were attributed to drought at least as the triggering factor. Our main objective was to reconstruct drought events that could be linked to Atlas cedar tree mortality using tree-ring series. We developed a Cedrus atlantica tree-ring width chronology in Chelia with a reliable period spanning from 1502 to 2008. Based on the relationship between chronology indices and instrumental precipitation data, we reconstructed total October-June precipitation. Dry events were identified using a threshold of 90% of the October-June mean instrumental precipitation. The unique drought event of 3-year period （1877-1879） could explain the tree mortality occurred in 1880. In terms of severity and frequency of droughts, the later half of the twentieth century seems to be the worst and may be responsible for the recent tree mortality.

关键词： Atlas cedar tree mortality meteorological drought dendrochronology precipitation reconstruction.

Co-Occurring Plant Species of the West African Critically Endangered Aubregrinia taïensis Heine, in Côte d’Ivoire

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American Journal of Plant Sciences 2023年第8期14卷 915-928页

作者： Doudjo Noufou Ouattara Hermann Hippolyte Tro Dofoungo Koné Akoua emilia Afanvi Doh Amed Coulibaly Adama Bakayoko Laboratoire de Botanique et Valorisation de la Diversité Végétale UFR Sciences de la Nature Université Nangui Abrogoua Abidjan C&#244te d’Ivoire Centre Suisse de Recherches Scientifiques en Cô te d’Ivoire (CSRS) Abidjan C&#244te d’Ivoire UFR Sciences Biologiques Université Pelefero Gon Coulibaly Korhogo C&#244te d’Ivoire

The Upper Guinea Forest is subject to heavy deforestation. In this context, many endemic and/or rare plant species are threatened with extinction. This is the case of Aubregrinia taïensis (Aubrév. & Pellegr.) Heine, a critically endangered Sapotaceae species, endemic to Côte d’Ivoire and Ghana. After 3 years of investigation in and around the Tai National Park (TNP) in the West of Côte d’Ivoire, only one individual of this species was located and no sexual reproductive organs (fruits, seeds) were observed. Woody plant species around this individual were inventoried in order to know the species that can co-occur with Aubregrinia taïensis. For that a plot of 30 m of diameter was established around the individual and all of the woody species of this circle were inventoried. Then, the taxonomic diversity, the chorology of the species, the conservation status and their life-form were recorded. A total of 130 woody plant species belonging to 51 families were collected in the site. The most represented families are Euphorbiaceae (12 spp.), Rubiaceae (10 spp.), Annonaceae (7 spp.), Fabaceae, Moraceae, Malvaceae (6 spp. each) while the most represented genera are Diospyros L. (4 spp.), Cola Schott & Endl. and Vitex L. (3 spp.). Species from the Guineo-Congolese Region (GC) are the most abundant (72%). They are followed by West African endemic species (GCW, 19%). Microphanerophytes (mp) are the most abundant and represent more than 40% of the species. Three vulnerable species were found in this plot: Campylospermum amplectens, Placodiscus boya and Trichoscypha cavalliensis. Thus, the preservation of this forest is more than necessary.

关键词： Co-Occurring Species Aubregrinia taïensis Forest Threatened Species Côte d’Ivoire

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狗狗也时尚

微型计算机 2019年第32期39卷 68-71页

作者： Hennes Mauritz emilia(图) 不详

不少人把饲养的宠物狗当作自己的孩子。除了给予它们可口的美食,还会经常给它们打扮。相信很多人在街上都看到过穿着衣服的小狗,有的很时尚、也有搞笑款,还有很可爱的……各种款式几乎都有。本期我们找来几只可爱的时尚小狗,和他们的主... 详细信息

不少人把饲养的宠物狗当作自己的孩子。除了给予它们可口的美食,还会经常给它们打扮。相信很多人在街上都看到过穿着衣服的小狗,有的很时尚、也有搞笑款,还有很可爱的……各种款式几乎都有。本期我们找来几只可爱的时尚小狗,和他们的主人聊天,了解了他们初次见面的情况、狗狗们的怪癖——当然还有无穷无尽的萌宠爱意。

关键词：宠物狗时尚初次见面美食可爱

Oxaliplatin-induced neuropathy and colo-rectal cancer patient's quality of life:Practical lessons from a prospective cross-sectional,real-world study

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World Journal of Clinical Cases 2022年第10期10卷 3101-3112页

作者： Iulian Prutianu Teodora Alexa-Stratulat Elena Octaviana Cristea Andrei Nicolau Diana Cornelia Moisuc Alina Alexandra Covrig Karina Ivanov Adina emilia Croitoru Monica Ionela Miron Mihaela Ioana Dinu Anca Viorica Ivanov Mihai Vasile Marinca Iulian Radu Bogdan Gafton SC MNT Healthcare Europe SRL Iasi 700021Romania University of Medicine and Pharmacy Grigore T Popa Iasi Iasi 700483Romania Regional Oncology Institute Iasi Iasi 700483Romania Oral and Maxillo-facial Surgery University of Medicine and Pharmacy Grigore T Popa IasiIasi 700021Romania Department of Medical Oncology Fundeni Clinical InstituteBucuresti 022328Romania University of Medicine and Pharmacy“Grigore T Popa” Iasi 700021Romania Department of Surgery Department of Surgical OncologyUniversity of Medicine and Pharmacy“Grigore T Popa”Regional Institute of OncologyIasi 700021Romania

BACKGROUND Colon cancer is one the most common forms of cancer in both *** to important progress in the field of early detection and effective treatment,colon and rectal cancer survivors currently account for 10%of cancer survivors ***,the effects of anti-cancer treatments,especially oxaliplatinbased chemotherapy,on the quality of life(QoL)have been less *** the incidence of severe chemotherapy-induced neuropathy(CIPN)in clinical studies is below 20%,data from real-world studies is scarce,and CIPN is probably under-reported due to patient selection and the patients’fear that reporting side-effects might lead to treatment *** To determine the impact of CIPN on QoL in colorectal cancer patients with a recent history of oxaliplatin-based *** We performed a prospective cross-sectional study in two major Romanian oncology tertiary hospitals—the Regional Institute of Oncology Ia?i(Iasi,Romania)and the Fundeni Clinical Oncology Institute(Bucharest,Romania).All consecutive patients with colon or rectal cancer,undergoing Oxaliplatin-based chemotherapy that consented to enroll in the study,were assessed by means of two questionnaires—the EORTC QQ-CR29(quality of life in colon and rectal cancer patients)and the QLQ-CIPN20(assessment of neuropathy).Several demographical,social,clinical and treatment data were also *** analysis was performed by means of SPSS *** student t test was used to assess the relationship between the QLQ-CIPN20 and QLQ-CR29 *** Meyer-curves were used to report 3-year progression-free survival(PFS)in patients that discontinued chemotherapy vs those that completed the recommended *** Of the 267 patients that fulfilled the inclusion criteria in the pre-specified time frame,101(37.8%)agreed to participate in the clinical *** the time of the enrolment in the study,over 50%of the patients had recently interrupted their oxaliplatin-based chemotherapy,mo

关键词： Colorectal cancer Oxaliplatin Neuropathy Quality of Life Recurrence-free survival Cross-sectional study

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名牌让你更自信?

Newton-科学世界 2004年第7期 87-90页

作者： Paola emilia Cicerone 陈英

犀牛角真的能增强性能力吗?音乐厅演奏的音乐一定比露天舞场的高雅吗々“品牌”能使一件衣服更漂亮吗?从根本上来说，我们是否受到一些表象的影响?其实，在我们的生活中，“安慰剂效用”无处不在，它的影响远比我们想象的要深刻．广泛... 详细信息

犀牛角真的能增强性能力吗?音乐厅演奏的音乐一定比露天舞场的高雅吗々“品牌”能使一件衣服更漂亮吗?从根本上来说，我们是否受到一些表象的影响?其实，在我们的生活中，“安慰剂效用”无处不在，它的影响远比我们想象的要深刻．广泛，甚至可以“蒙骗”那些专门研究行为学的人。

关键词：社会背景心理因素消费心理名牌产品

Validation of the Trail Making Test B for the Cognitive Assessment of Patients with Cancer in Palliative Care

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Open Journal of Statistics 2014年第6期4卷 435-445页

作者： Juliano dos Santos Cibele Andrucioli de Mattos Pimenta Geana Paula Kurita Patricia emilia Braga Per Sjogren National Cancer Institute-HC Ⅲ Rio de JaneiroBrazil Department of Medical Surgical Nursing School of NursingUniversity of Sao PauloSao PauloBrazil Rigshospitalet Section of Palliative MedicineMultidisciplinary Pain CentreCopenhagenDenmark

Introduction: Cognitive impairment is common in patients with cancer;however, studies examining the adaptation and validation of instruments for use in patients with cancer are scarce. Purpose: The purpose of this study was to validate the Trail Making Test B (TMT-B) for use in patients with cancer. Methods: Ninety-four outpatients receiving palliative treatment and 39 healthy companions were assessed. Patients were tested with the TMT-B and answered questions regarding the presence and intensity of pain, fatigue, quality of sleep, anxiety, and depression, at two time points with a 7-day inter-assessment interval. Results: The instrument discriminated between patients, who were slower, and healthy companions with respect to the time required to complete the test, but not in terms of the number of errors. The test was stable for the healthy companions across the two assessments in terms of time to complete the TMT-B and the number of errors;for patients, the instrument was stable only for the number of errors. Performance on the TMT-B did not correlate with pain, fatigue, depression, anxiety, or sensation of rest. Conclusions: TMT-B cannot be considered fully validated. Further studies incorporating and comparing other instruments evaluating executive function and mental flexibility are needed.

关键词： Cognition Executive Function Hospice Care Neoplasms Neuropsychological Tests Validation Studies

Confirmation of diagnosis in Romanian children with DFNB1 related hearing loss

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American Journal of Molecular Biology 2013年第4期3卷 229-234页

作者： Cristina Dragomir Adriana Stan Stan Dragos Tiberiu Stefanescu Lorand Savu Codrut Sarafoleanu Adrian Toma emilia Severin Carol Davila University of Medicine and Pharmacy 37 Dionisie Lupu St Bucharest Romania Davila University of Medicine and Pharmacy 37 Dionisie Lupu St Bucharest Romania Genetic Lab 43B Ghencea Avenue Bucharest Romania Panait Sirbu Hospital Calea Giulesti Bucharest Romania

DFNB1 locus has been linked to a nonsyndromic “invisible disability” called congenital sensorineural hearing loss and deafness. Mutations of GJB2 and GJB6 genes are associated with deafness at the DFNB1 locus. The diagnosis of DFNB1 is made with molecular genetic testing. DNA-based testing can be used both prenatally and postnatally. Purpose: to get evidence for implementation of newborn hearing screening programs at national level;to use the molecular testing of children at risk for confirmation of diagnosis and early intervention. OAEs and ABR were performed for 4303 newborns. Audiologic evaluation of 38 children suspected of having hearing loss was performed too. Physical examinations and family history were used to get information about congenital deafness. DNA from blood samples was isolated, and two PCR multiplex assays were developed to detect DFNB1 mutations. Only 23 newborns were screened positive. Newborns were referred to audiologic evaluation, genetic counseling and testing for the etiologic diagnosis. Physical examination revealed no other abnormal findings. GJB2 mutations were detected in 36.03% of patients, and all of them have 35delG mutation. None of them was found to have GJB6 mutations. Our results suggested that molecular testing was an accurate method of early determining cause of congenital hearing loss and helped us to exclude GJB6 gene from the routine hearing screening protocol.

关键词： DFNB1 Molecular Genetic Testing GJB2 GJB6

Phenylacetylglutaminate and Phenylacetate in Combination Upregulate VDUP1, Cause Cell Cycle Blockade and Apoptosis in U87 Glioblastoma Cells

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Journal of Cancer Therapy 2012年第3期3卷 192-200页

作者： Sonali S. Patil Stanislaw R. Burzynski emilia Mrowczynski Krzysztof Grela Sridar V. Chittur Center for Functional Genomics University at Albany Rensselaer USA. Department Cell and Molecular Biology Burzynski Research Institute Stafford USA

Phenylacetylglutaminate (PG) and Phenylacetate (PN) are metabolites of Phenylbutyrate (PB) and are constituents of antineoplaston AS2-1. These are sodium salts of amino acid derivative and carboxylic acid that inhibit the growth of neoplastic cells without growth inhibitory effect in normal cells. The aim of this study was to identify molecular pathways involved in the anti-proliferative effect of antineoplastons. Using a total human genome microarray we have found that 1) Vitamin D3 upregulated protein (VDUP1) is significantly upregulated in response to PG and PN in the U87 glioblastoma cells;2) Isobologram analysis shows that PG and PN act in an additive or synergistic manner to effectively suppress proliferation of U87 cells;3) PG and PN cause cell cycle arrest, changes in expression of several cell cycle genes and suppress expression and activity of the G2/M checkpoint kinase, CHK1. The multiple cellular targets possibly make these compounds effective anti-proliferative agents. We propose that PG and PN in combination target important cellular pathways and upregulate VDUP1 leading to detachment-induced apoptosis in cancer cells.

关键词： Glioblastoma VDUP1 Phenylacetylglutaminate Phenylacetate Apoptosis Drug Combination