检索结果-南通市图书馆

Optimization of Cooperative RelayingMolecular Communications for Nanomedical Applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第2期138卷 1259-1275页

作者： eman S.Attia Ashraf A.M.Khalaf Fathi E.Abd El-Samie Saied M.Abd El-atty Konstantinos A.Lizos Osama Alfarraj Heba M.El-Hoseny Department of Electrical Engineering Faculty of EngineeringMinia UniversityMinia61111Egypt Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Department of Informatics Faculty of Mathematics and Natural SciencesUniversity of Oslo(UiO)OsloNorway Computer Science Department Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Department of Computer science The Higher Future Institute for Specialized Technological StudiesEl ShoroukEgypt

Recently,nano-systems based on molecular communications via diffusion(MCvD)have been implemented in a variety of nanomedical applications,most notably in targeted drug delivery system(TDDS)***,because the MCvD is unreliable and there exists molecular noise and inter symbol interference(ISI),cooperative nano-relays can acquire the reliability for drug delivery to targeted diseased cells,especially if the separation distance between the nano transmitter and nano receiver is *** this work,we propose an approach for optimizing the performance of the nano system using cooperative molecular communications with a nano relay scheme,while accounting for blood flow effects in terms of drift *** fractions of the molecular drug that should be allocated to the nano transmitter and nano relay positioning are computed using a collaborative optimization problem solved by theModified Central Force Optimization(MCFO)*** the previous work,the probability of bit error is expressed in a closed-form *** is used as an objective function to determine the optimal velocity of the drug molecules and the detection threshold at the nano *** simulation results show that the probability of bit error can be dramatically reduced by optimizing the drift velocity,detection threshold,location of the nano-relay in the proposed nano system,and molecular drug budget.

关键词： Nanomedical system molecular communication cooperative relay optimization

Comprehensive analysis of the role of ubiquitin-specific peptidases in colorectal cancer:A systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第1期16卷 197-213页

作者： eman Al-Balushi Amina Al Marzouqi Shima Tavoosi Amir Hossein Baghsheikhi Arash Sadri Leyla Sharifi Aliabadi Mohammad-Mahdi Salarabedi Syed Azizur Rahman Nabeel Al-Yateem Alireza Mosavi Jarrahi Aram Halimi Mohammad Ahmadvand Wael M Abdel-Rahman College of Health Sciences University of SharjahSharjah 27272United Arab Emirates Department of Biology Faculty of SciencesUniversity of IsfahanIsfahan 81746-73441Iran Department of Biology Science and Research BranchIslamic Azad UniversityTehran 11365/4435Iran Students’Scientific Research Center Tehran University of Medical SciencesTehran ***Iran Cell Therapy and Hematopoietic Stem Cell Transplantation Research Center Research Institute for OncologyHematologyand Cell TherapyTehran University of Medical SciencesTehran ***Iran Student Research Committee School of MedicineShahid Beheshti University of Medical SciencesTehran ***Iran Department of Nursing University of SharjahSharjah 27272United Arab Emirates Cancer Research Centre Shahid Beheshti University of Medical SciencesTehran ***Iran Department of Medical Laboratory Sciences University of SharjahSharjah 27272United Arab Emirates

BACKGROUND Colorectal cancer(CRC)is the third most frequent and the second most fatal *** search for more effective drugs to treat this disease is ongoing.A better understanding of the mechanisms of CRC development and progression may reveal new therapeutic ***-specific peptidases(USPs),the largest group of the deubiquitinase protein family,have long been implicated in various *** have been numerous studies on the role of USPs in CRC;however,a comprehensive view of this role is *** To provide a systematic review of the studies investigating the roles and functions of USPs in *** We systematically queried the MEDLINE(via PubMed),Scopus,and Web of Science *** Our study highlights the pivotal role of various USPs in several processes implicated in CRC:Regulation of the cell cycle,apoptosis,cancer stemness,epithelial–mesenchymal transition,metastasis,DNA repair,and drug *** findings of this study suggest that USPs have great potential as drug targets and noninvasive biomarkers in *** dysregulation of USPs in CRC contributes to drug resistance through multiple *** Targeting specific USPs involved in drug resistance pathways could provide a novel therapeutic strategy for overcoming resistance to current treatment regimens in CRC.

关键词： Ubiquitin-specific peptidases Colorectal cancer Deubiquitinase protein family Drug target discovery Biomarker discovery

Prevalence and associated factors of clubfoot in the eastern province of Saudi Arabia: A hospital-based study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2024年第7期15卷 635-641页

作者： Ammar K a.omra. Bandar A Alzahrani Bader S Alanazi Mohammed A Alharbi Loay M Bojubara eman M Alyaseen Department of Orthopedic College of MedicineImam Abdulrahman bin Faisal UniversityDammam 34212Saudi Arabia College of Medicine Imam Abdulrahman bin Faisal UniversityDammam 34212Saudi Arabia College of Medicine Arabian Gulf UniversityManama 329Bahrain

BACKGROUND Clubfoot,or congenital talipes equinovarus,is a widely recognized cause of disability and congenital deformity worldwide,which significantly impacts the quality of *** management of clubfoot requires long-term,multidiscip-linary *** is important to understand how common this condition is in order to assess its impact on the ***,few studies have investigated the prevalence of clubfoot in Saudi *** To determine the prevalence of clubfoot in Saudi Arabia via the patient population at King Fahad University Hospital(KFUH).METHODS This was a retrospective study conducted at one of the largest hospitals in the country and located in one of the most densely populated of the administrative *** Of the 7792 births between 2015 to 2023 that were included in the analysis,42 patients were diagnosed with clubfoot,resulting in a prevalence of 5.3 per 1000 live births at *** The observed prevalence of clubfoot was significantly higher than both global and local estimates,indicating a substantial burden in the study population.

关键词： Clubfoot Talipes equinovarus Congenital talipes equinovarus Prevalence Saudi Arabia

Erratum to “Plant Defense against Necrotrophic Pathogens” [American Journal of Plant Sciences 11(12) (2020) 2122-2138]

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2024年第2期15卷 122-138页

作者： Mahmoud H. Ghozlan Nikita Gambhir eman EL-Argawy Serkan Tokgöz Dilip K. Lakshman Amitava Mitra University of Nebraska Lincoln NE USA USDA-ARS Beltsville MD USA

The original online version of this article (Ghozlan, M.H., EL-Argawy, E., Tokgöz, S., Lakshman, D.K. and Mitra, A. (2020) Plant Defense against Necrotrophic Pathogens. American Journal of Plant Sciences, 11, 2122-2138. https://***/10.4236/ajps.2020.1112149) was published mistakenly without another co-author, Nikita Gambhir. In this regard, we revise authors and “how to cite” sections by adding her name.

关键词： Effectors Host Immunity Signaling P/MAMP ETI Disease Resistance

Evolving strategies: Enhancements in managing eosinophilic esophagitis in pediatric patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Pediatrics 2024年第1期13卷 14-22页

作者： Ahmed Elghoudi Doaa Zourob eman Al Atrash Fatima Alshamsi Manal Alkatheeri Hassib Narchi Rana Bitar Department of Pediatric Sheikh Khalifa Medical CityAbu DhabiUnited Arab Emirates Division of Pediatric Gastroenterology Sheikh Khalifa Medical CityAbu DhabiUnited Arab Emirates Pediatric Residency Program Sheikh Khalifa Medical CityAbu DhabiUnited Arab Emirates College of Medicine and Health Sciences United Arab Emirates UniversityAlainAbu DhabiUnited Arab Emirates

Eosinophilic esophagitis is a newly recognized disease first described about 50 years *** definition,diagnosis,and management have evolved with new published consensus guidelines and newly approved treatment available to pediatricians,enabling a better understanding of this disease and more targeted treatment for *** describe the definition,presentation,and diagnosis of eosinophilic esophagitis including management,challenges,and future directions in *** definition,diagnosis,and management of eosinophilic esophagitis have evolved over the last 50 *** guidelines and newly approved biologic treatment have enabled pediatricians to better understand this disease and allow for more targeted treatment for *** describe the definition,presentation,diagnosis,management,and treatment in addition to the challenges and future directions of eosinophilic esophagitis management in children.

关键词： Eosinophilic esophagitis Esophagitis Gastroesophageal reflux disease Food allergy Dysphagia

Graphical Transformation of OWL Ontologies to Event-B Formal Models

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第2期70卷 3733-3750页

作者： eman H.Alkhammash Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia

Formal methods use mathematical models to develop *** are formal specifications that provide reusable domain knowledge *** have been successfully used in several data-driven applications,including data ***,the creation of formal models from informal requirements demands skill and ***,inconsistency,imprecision,and incompleteness are major problems in informal *** solve these problems,it is necessary to have methods and approaches for supporting the mapping of requirements to formal *** purpose of this paper is to present an approach that addresses this challenge by using theWeb Ontology Language(OWL)to construct Event-B formal models and support data *** approach reduces the burden of working with the formal notations of OWL ontologies and Event-B models and aims to analyze domain knowledge and construct Event-B models from OWL ontologies using visual *** idea is based on the transformation of OntoGraf diagrams of OWL ontologies to UML-B diagrams for the purpose of bridging the gap between OWL ontologies and Event-B *** data exploration assists with both data analysis and the development of Event-B formal *** manage complexity,Event-B supports stepwise refinement to allow each requirement to be introduced at themost appropriate stage in the development ***-B supports refinement,so we also introduce an approach that allows us to divide and layer OntoGraf diagrams.

关键词： Data analysis OWL ontologies event-B formal method refinement requirements OntoGraf

Vital Parameters Assessments of Starvation Tolerance of in vitro Populus alba Culture

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phyton-International Journal of Experimental Botany 2022年第4期91卷 889-902页

作者： Mohamed Fathy Ahmed eman Zakaria Ahmed Salman Aloufi Mohammed Alqurashi Amal Alyamani eman Fayad eman Tawfik Hussien Horticulture Department Faculty of AgricultureAin Shams UniversityCairo11566Egypt Botany and Microbiology Department Faculty of ScienceHelwan UniversityCairo11795Egypt Department of Biotechnology Faculty of SciencesTaif UniversityTaif21944Saudi Arabia

Populus alba is a large woody deciduous *** plant has been introduced to shooting,then multiplication of rooting on Murashige and Skoog(MS)*** work was designed to estimate the effect of two factors(low levels of 1-Naphthaleneacetic acid NAA and sucrose)on *** response resulting in 6 treatments compared to the control,with twelve measured *** was a significant difference in some measurements in morphology,like plantlets fresh-weight,shoot-,root-length,and leaf *** the physiological measurements,there were significant differences in all the measured *** low concentrations of sucrose and media composition/power(MS grams/L)led to starvation in plants;however,these conditions led to enhancement in some morphological and physiological parameters to overcome the starvation effect,compared to the *** RAPD-PCR molecular marker(four decamers)was used to evaluate the new individuals’genetic variation(instability),resulting in a total polymorphism percentage of 50.83%.It was formerly known that the plantlets were identical to each other and to the mother *** this study,however,the use of distinct media power,hormonal and sucrose levels resulted in molecular variation reflected in ***’s morphological and physiological responses.

关键词： Genetic stability Populus alba RAPD-PCR somaclonal variations starvation

Deep Learning for Image Segmentation: A Focus on Medical Imaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

计算机、材料和连续体（英文） 2023年第4期75卷 1995-2024页

作者： Ali F.Khalifa eman Badr Faculty of Computers and Artificial Intelligence Cairo UniversityGiza12613Egypt Zewail City of Science and Technology Giza12578Egypt

Image segmentation is crucial for various research areas. Manycomputer vision applications depend on segmenting images to understandthe scene, such as autonomous driving, surveillance systems, robotics, andmedical imaging. With the recent advances in deep learning (DL) and itsconfounding results in image segmentation, more attention has been drawnto its use in medical image segmentation. This article introduces a surveyof the state-of-the-art deep convolution neural network (CNN) models andmechanisms utilized in image segmentation. First, segmentation models arecategorized based on their model architecture and primary working ***, CNN categories are described, and various models are discussed withineach category. Compared with other existing surveys, several applicationswith multiple architectural adaptations are discussed within each category.A comparative summary is included to give the reader insights into utilizedarchitectures in different applications and datasets. This study focuses onmedical image segmentation applications, where the most widely used architecturesare illustrated, and other promising models are suggested that haveproven their success in different domains. Finally, the present work discussescurrent limitations and solutions along with future trends in the field.

关键词： Deep learning medical imaging convolution neural network image segmentation medical applications survey

Mental Health Consequences among Sudanese Due to the Armed Conflicts and Civil Unrest of 2023: One Year Later

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2024年第4期12卷 21-37页

作者： Sahar Moawia Balla Elnour Nahla Yousif Osman Mohammed Saeed Awadia Babiker Mohammed Osman Abeer Alawad Hassan eman Mohamed Nour Hamad Alneel Mustafa Rowa Abdelmonem Sidig Hamato Malaz Mohamed Khair Alsafi Mohamed Amna Alnaim Mohamed Ahmed Osman Awab Abdelbagi Mustafa Ahmed Jalal Abdelrasool Hassan Eltaib Department of Family Medicine Health Gates Riyadh Saudi Arabia Family Medicine Department Ultracare Home Health Care Riyadh Saudi Arabia Psychiatic Department Erada Hospital and Mental Health Alkharj Saudi Arabia Family Medicine Department Ahmed Gasim Diabetic Center Portsudan Sudan QCHP Qatar Qatar Primary Care Najran Health Cluster Najran Saudi Arabia Emergency Department Best Care Hospital Khartoum Sudan Family Medicine Department Mouwasat Hospital Khobar Saudi Arabia

Aim: To investigate depression, anxiety, PTSD, and insomnia levels among Sudanese citizens after a year has passed since the start of Armed Forces conflict in Sudan. Methods: An online survey was distributed. It is composed of five parts, covering the following areas: 1) sociodemographic data;2) depression assessment;3) generalized anxiety disorder assessment;4) post-traumatic stress disorder assessment;and 5) insomnia assessment. Statistical Package for Social Sciences version 27 was used for data analysis;frequency and percentage were used to describe the qualitative variables. Spearman’s correlation analysis and Chi-square test were used for correlation and association analysis;a P-value equal to or less than 0.05 was considered statistically significant. Results: The study included 283 participants, primarily female (76.0%), with a mean age of 35.26 ± 6.96 years. The majority of participants were married (50.5%) and had a university level of education (50.2%). At the start of the war, 70.3% of participants were inside the war zones, and at the time of data collection, 73.5% were outside Sudan. The length of stay in the war zone ranged from 1 to 300 days, with a mean of 48.59 ± 70.284 days. Additionally, 63.3% of participants stated that they did not receive any form of mental health intervention, and the remaining did not provide an answer. There was a high prevalence of moderate-severe depression (50.5%), moderate anxiety (35.3%), PTSD (56.5%), and sub-threshold insomnia (53.4%) among the participants. Correlation analyses revealed associations between demographic factors such as sex, age, marital status, and education and mental health issues. Notably, female participants showed a higher prevalence of PTSD (53.0%) compared to male participants (67.6%). Conclusions: There is a substantial impact of war-related trauma on mental health, revealing a high prevalence of moderate-severe depression, moderate anxiety, PTSD, and sub-threshold insomnia among the particip

关键词： Sudan War Conflict Mental Health