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Performance investigation of LAMBDA and bootstrapping methods for PPP narrow-lane ambiguity resolution

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Geo-Spatial Information Science 2021年第4期24卷 604-614页

作者： omer Faruk Atiz Sermet Ogutcu Salih Alcay Pan Li Ilkay Bugdayci Department of Geomatics Engineering Necmettin Erbakan UniversityKonyaTurkey Department of Geodesy and Remote Sensing German Research Centre for GeosciencesPotsdamGermany

Precise point positioning with ambiguity resolution(PPP-AR)is a powerful tool for geodetic and time-constrained applications that require high *** performance of PPP-AR highly depends on the reliability of the correct integer carrier-phase ambiguity *** this study,the performance of narrow-lane ambiguity resolution of PPP using the Least-squares AMBiguity Decorrelation(LAMBDA)and bootstrapping methods is extensively investigated using real data from 55 IGS stations over one-month in *** PPP with 24-,12-,8-,4-,2-,1-and½-h sessions using two different cutoff angles(7°and 30°)was conducted with three PPP modes:***-float and two kinds of ambiguity-fixed PPP using the LAMBDA and bootstrapping methods for narrow-lane AR,*** results show that the LAMBDA method can produce more reliable results for 2 hour and shorter observation sessions com-pared with the bootstrapping method using a 7°cutoff *** a 30°cutoff angle,the LAMBDA method outperforms the bootstrapping method for observation sessions of 4 h and *** long observation times,the bootstrapping method produced much more accurate coordinates compared with the LAMBDA method without considering the wrong fixes *** results also show that occurrences of fixing the wrong integer ambiguities using the bootstrapping method are higher than that of the LAMBDA method.

关键词： Ambiguity resolution narrow-lane Precise point positioning(PPP) LAMBDA bootstrapping

Joint optimization for secure ambient backscatter communication in NOMA-enabled IoT networks

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Digital Communications and Networks 2023年第1期9卷 264-269页

作者： Wali Ullah Khan Furqan Jameel Asim Ihsan omer Waqar Manzoor Ahmed Interdisciplinary Centre for Security Reliability and Trust(SnT)/SigComUniversity of LuxembourgLuxembourg Department of Communications and Networking Aalto University02150EspooFinland Department of Communication and Information Engineering Shanghai Jiao Tong UniversityShanghai200240China Department of Engineering Thompson Rivers University(TRU)British Columbia(BC)Canada College of Computer Science and Technology Qingdao UniversityQingdao266071China

Non-Orthogonal Multiple Access(NOMA)has emerged as a novel air interface technology for massive connectivity in Sixth-Generation(6G)*** recent integration of NOMA in Backscatter Communication(BC)has triggered significant research interest due to its applications in low-powered Internet of Things(IoT)***,the link security aspect of these networks has not been well *** article provides a new optimization framework for improving the physical layer security of the NOMA ambient BC *** system model takes into account the simultaneous operation of NOMA IoT users and the Backscatter Node(BN)in the presence of multiple EavesDroppers(EDs).The EDs in the surrounding area can overhear the communication of Base Station(BS)and BN due to the wireless broadcast ***,the chief aim is to enhance link security by optimizing the BN reflection coefficient and BS transmit *** gauge the performance of the proposed scheme,we also present the suboptimal NOMA and conventional orthogonal multiple access as benchmark *** Carlo simulation results demonstrate the superiority of the NOMA BC scheme over the pure NOMA scheme without the BC and conventional orthogonal multiple access schemes in terms of system secrecy rate.

关键词： 6G Non-orthogonal multiple access Ambient backscatter communication Internet-of-things Joint optimization Physical layer security

Mutual Authentication Protocols for RFID Systems

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International Journal of Automation and computing 2008年第4期5卷 348-365页

作者： Ashrar A.omer Johnson P.Thomas Department of Computer Science Oklahoma State University

With the availability of low-cost radio frequency identification (RFID) tags,security becomes an increasing concern. However,such tags do not permit complex cryptographic functions due to their computational,communications,and storage limitations. In this paper,we investigate the security issues and requirements of RFID systems,and propose ultra-light weight and light weight protocols for low-cost RFID *** proposed protocols has been applied to a supply chain management system.

关键词： Security mutual authentication supply chain management RFID Systems.

Place of intravitreal dexamethasone implant in the treatment armamentarium of diabetic macular edema

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World Journal of Diabetes 2021年第8期12卷 1220-1232页

作者： omer Karti Ali Osman Saatci Department of Ophthalmology İzmir Democracy Universityİzmir 35330Turkey Department of Ophthalmology Dokuz Eylul Universityİzmir 35330Turkey

Diabetic macular edema(DME)is a very important and well-known cause of visual loss in ***-retina barrier disruption and consequent intraretinal fluid accumulation may lead to retinal thickening at the posterior pole namely *** though it is not clearly understood,current evidence suggests that chronic low-grade inflammation characterized with various cytokines has a major role in the occurrence of *** trials are continuously shaping our treatment approaches for the eyes with ***,vascular endothelial growth factor(VEGF)inhibitor and steroid administrations are the main alternatives in DME ***(DEX)implant(Ozurdex®;Allergan,Inc.,Irvine,CA,United States)was approved by the United States Food&Drug Administration in 2014 for DME *** implant is made up of a biodegradable solid copolymer that is broken down by releasing its active ingredient into the vitreous cavity over *** release feature of this sustained-release drug delivery system ensures its efficacy for up to 6 mo with an acceptable and manageable safety *** implant provides a favorable anatomical and functional outcome in DME as shown in several randomized-controlled studies but has a relatively higher ocular side-effect profile such as increased risk of cataract formation and raised intraocular pressure when compared to the gold standard anti-VEGF ***,DEX implant becomes the second-line treatment option demonstrating inadequate clinical response to anti-VEGF ***,it can be preferred as the first-line treatment in vitrectomized and pseudophakic *** in some selected conditions DEX implant is favored over anti-VEGF agents where the use of VEGF-inhibitors is either inappropriate or contraindicated such as the patients with a recent history of a major cardiovascular or cerebrovascular event,pregnancy and noncompliant to frequent *** mini-review briefly overviews the efficacy,safety profile and complications o

关键词： Dexamethasone implant Diabetic macular edema Diabetic retinopathy Drugdelivery system Glaucoma Pharmacotherapy

Elevated uric acid level： the chicken or the egg？

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Journal of Geriatric Cardiology 2016年第4期13卷 367-368页

作者： Mehmet Dogan omer UZ Burhan Bicakci Ankara Mevki Military Hospital Department of Cardiology Ankara Turkey Gulhane Military Medical Academy Haydarpasa Training Hospital Department of Cardiology lstanbul Turkey

The article entitled Predictive value of serum uric acid on left atrial spontaneous echo contrast in non-valvular atrialftbrillation patients by Liao, et al. has given important data regarding the association between uric acid level and spontaneous echo contrast in patients with non-valvular atrial fibrillation. This relationship has become an attrac- tive interest and hereafter more comprehensive studies should be conducted. We would like to contribute to the study for some methodological points.

关键词： Alcohol Atrial fibrillation Hypothyroidism Spontaneous echo contrast Uric acid

Early COVID-19 Symptoms Identification Using Hybrid Unsupervised Machine Learning Techniques

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Computers, Materials & Continua 2021年第10期69卷 747-766页

作者： omer Ali Mohamad Khairi Ishak Muhammad Kamran Liaquat Bhatti School of Electrical and Electronic Engineering Universiti Sains Malaysia(USM)Nibong Tebal14300Malaysia Department of Electrical Engineering NFC Institute of Engineering and Technology(NFC IET)Multan60000Pakistan

The COVID-19 virus exhibits pneumonia-like symptoms,including fever,cough,and shortness of breath,and may be *** COVID-19 contraction experiments require comprehensive clinical procedures at medical *** studies help to make a correct diagnosis of COVID-19,where the disease has already spread to the organs in most *** and early diagnosis is indispensable for providing patients with the possibility of early clinical diagnosis and slowing down the disease ***,clinical investigations in patients with COVID-19 have revealed distinct patterns of breathing relative to other diseases such as flu and cold,which are worth *** supervised Machine Learning(ML)based techniques mostly investigate clinical reports such as X-Rays and Computerized Tomography(CT)for disease *** strategy relies on a larger clinical dataset and does not focus on early symptom *** this end,an innovative hybrid unsupervised ML technique is introduced to uncover the probability of COVID-19 occurrence based on the breathing patterns and commonly reported symptoms,fever,and ***,various metrics,including body temperature,breathing and cough patterns,and physical activity,were considered in this ***,a lightweight ML algorithm based on the K-Means and Isolation Forest technique was implemented on relatively small data including 40 *** proposed technique shows an outlier detection with an accuracy of 89%,on average.

关键词： COVID-19 symptoms identification machine learning isolation forest k-means

Sodium Fluoride Induces Hepato-Renal Oxidative Stress and Pathophysiological Changes in Experimental Animals

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Open Journal of Apoptosis 2018年第1期7卷 1-23页

作者： Azab elsayed Azab Mohamed omer Albasha J. M. Jbireal Almokhtar A. Adwas Department of Physiology Faculty of Medicine Sabratha University Sabratha Libya Department of Zoology Faculty of Science Alejelat Zawia University Alejelat Libya Department of Pharmacology Faculty of Medicine Sabratha University Sabratha Libya

The liver is a primary site for xenobiotics detoxification, and its metabolism is readily altered by toxicity. The kidney is a common target for toxic xenobiotics due to its capacity to extract and concentrate toxic substances by highly specialized cells. So, they are the target organs of sodium fluoride toxicity. The aim of this review is to highlight on hepatorenal oxidative stress and pathophysiological changes induced by treatment of experimental animals with sodium fluoride. Our review shows fluoride toxicosis caused an elevation in the serum activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase, acid phosphatase, and the level of total bilirubin, and reduction in the serum levels of total protein, albumin, and globulins, and serious histopathological changes in the hepaic tissues. Also, NaF administration caused increases in serum urea, creatinine, uric acid, sodium ions, and chloride ions levels and serious histopathological changes in the kidney tissues. Treatment of experimental animals with NaF induced oxidative stress in hepatic and renal tissues. It can be concluded that administration of sodium fluoride to experimental animals induced oxidative stress, serious hepatorenal histopathological changes, and disturbance in liver and kidney functions. So, human should be advised to decrease exposure to sodium fluoride to decrease the harmful effects of NaF on liver and kidney.

关键词： Sodium Fluoride Toxicity Oxidative Stress Hepatorenal Histopathological Changes Hepatorenal Pathophysiological Changes

Raloxifene-loaded and aptamer-bonded exosomes induce autophagic and apoptotic death in HeLa cells by enhancing the lysosomotropic effect

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BIOCELL 2023年第5期47卷 1051-1063页

作者： omer ERDOGAN GULEN MELIKE DEMIRBOLAT OZGE CEVIK Department of Medical Biochemistry School of MedicineAydin Adnan Menderes UniversityAydin09010Turkey Department of Pharmaceutical Technology Faculty of PharmacyAcibadem Mehmet Ali Aydinlar UniversityIstanbul34758Turkey

Background:Raloxifene,a selective estrogen receptor modulator,is also known to be a lysosomotropic *** bioavailability of raloxifene is around 2%due to extensive hepatic *** are nanosized vesicles that are naturally released from ***:In this study,exosomes released from HeLa cervical cancer cells were loaded with raloxifene to increase its bioavailability,and an aptamer was attached to the exosome membrane for targeting only HeLa *** of exosomes isolated from HeLa cells was performed by transmission electron microscopy,zeta sizer,and western *** addition,the cytotoxic,apoptotic,autophagic,and lysosomotropic effects of the prepared Exo-Apt-Ral formulation on HeLa cervical cancer cells were ***:According to zeta analysis,the sizes of the empty exosome and Exo-Apt-Ral formulation were measured as 66±12 and 120±21 nm,*** was a rise in the lysosomal permeability of HeLa cells after the Exo-Apt-Ral *** addition,both apoptotic and autophagic death mechanisms were triggered in HeLa cells after the Exo-Apt-Ral ***:This study showed that raloxifene functionalized by loading into aptamer-bound exosomes can be a new targeted drug carrier system for cervical cancer.

关键词： Aptamer Autophagy Cervical cancer Exosomes Raloxifene

Red blood cell distribution width is worthwhile when interpreted with other inflammatory markers

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Journal of Geriatric Cardiology 2015年第4期12卷 457-458页

作者： Mehmet Dogan Ugur Kucuk omer Uz Department of Cardiology Crulhane Military Medical Academy Haydarpasa Hospital Tibbiye Street Uskudar Istanbul Turkey

To the Editor In a recent issue of Journal of Geriatric Cardiology, we read the article by LIU, et al. with interest.~lJ They aimed to investigate whether red cell distribution width （RDW） had a relationship with mortality in elderly patients after percuta- neous coronary intervention （PCI）. The authors concluded that, RDW is an independent predictor of the increased in- termediate-term all-cause mortality in elderly patients after PCI. The easy availability of testing for RDW at no addi- tional cost may encourage its broader use in clinical practice We would like to thank the authors for their comprehensive contribution.

关键词： Percutaneous coronary intervention Red cell distribution width The elderly