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Metagenomics and volatile profile of Turkish artisanal Tulum cheese microbiota

Food Bioscience 2022年第1期45卷 204-213页

作者： Yekta Gezginc Tugba Karabekmez-Erdem Hazel Dilsad Tatar elif coskun daggecen Sermet Ayman Ismail Akyol Kahramanmaras Sutcu Imam University Faculty of Engineering and ArchitectureDepartment of Food EngineeringahramanmarasTurkey Kahramanmaras Sutcu Imam University Vocational School of Technical SciencesDepartment of Food ProcessingKahramanmarasTurkey Kahramanmaras Sutcu Imam University Faculty of AgricultureDepartment of Agricultural BiotechnologyKahramanmarasTurkey Ankara University Faculty of AgricultureDepartment of Animal ScienceAnkaraTurkey

Turkish artisanal Tulum cheese is a traditional raw milk cheese and starter cultures are not used for ripening *** this study,16S rRNA amplicon-based sequencing approach was used for determining bacterial diversity in Tulum *** volatile organic compound(VOC)profile which contributes to sensory properties of the cheeses was determined via solid-phase microextraction combined with gas chromatography-mass spectrometry(GC-MS/SPME)and correlated with the *** Tulum cheese samples,Lactobacillaceae(30,71%)phylum widely varied but Streptococcaceae(59,86%)was *** mainly belongs to the four dominant genera of lactic acid bacteria(LAB)and includes Lactobacillus,Lactococcus,Streptococcus and *** bacterial diversity of TC5 sample was much higher than that of other ***,several species of non-starter LAB were frequently detected.A total of 36 volatile compounds were identified including hydrocarbons(3),acids(13),alcohols(5),ketones(3),aldehydes(3),esters(8)and miscellaneous compound(1).Pentadecanoic acid,octadecanoic acid,tetradecanoic acid,octanoic acid,hexanoic acid were determined to be dominant in all cheese samples and to be related to microbial ***,the sensory profiles of the samples were *** most popular TC6 did not contain 2-butanone and hexanal from the volatile organic compound(VOC)values,while in the most unpopular TC3,2-butanone(7.73%)and hexanal(5.95%)were found to be the *** outcome of this study will contribute to literature on bacterial diversity and aromatic profile of Tulum cheese which should be investigated in order to improve quality and safety.

关键词： Microbiota 16S rRNA profiling Metagenomics Tulum cheese Volatile profile

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A predictive score for retinopathy of prematurity by using clinical risk factors and serum insulin-like growth factor-1 levels

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International Journal of Ophthalmology(English edition) 2017年第11期10卷 1722-1727页

作者： Yesim coskun Ceyhun Dalkan Ozge Yabas Ozlem Onay Demirel elif Samiye Bayar Sibel Sakarya Tuba Muftuoglu Dilaver Ersanli Nerin Bahceciler ipek Akman Department of Pedialrics Bahcesehir University Medical Faculty Medical Park Goztepe Hospital Istanbul 34732 Turkey Department of Pediatrics Division of Neonatology Near East University Nicosia 99138 North Cyprus Department of Ophtalmotology Bahce~ehir University Medical Faculty Medical Park Goztepe Hospital Istanbul 34732 Turkey Department of Biochemistry Bahcesehir University Medical Faculty Medical Park Goztepe Hospital Istanbul 34732 Turkey Department of Public Health Marmara University Medical Faculty Istanbu 134890 Turkey Department of Biochemistry GATA Haydarpa~a Hospital Istanbul 34668 Turkey Department of Ophtalmotology GATA Haydarpasa Hospital Istanbu134668 Turkey Department of Pediatrics Near East University Nicosia 99138 North Cyprus

AIM：To detect the impact of insulin-like growth factor-1（IGF-1）and other risk factors for the early prediction of retinopathy of prematurity（ROP）and to establish a scoring system for ROP prediction by using clinical criteria and serum IGF-1 ***：The study was conducted with 127 preterm ***-1 levels in the 1st day of life,1st,2nd,3rd and4th week of life was *** score was established after logistic regression analysis,considering the impact of each variable on the occurrences of any stage ROP.A validation cohort containing 107 preterm infants was included in the study and the predictive ability of ROP score was ***：Birth weights（BW）,gestational weeks（GW）and the prevalence of breast milk consumption were lower,respiratory distress syndrome（RDS）,bronchopulmonarydysplasia（BPD）and necrotizing enterocolitis（NEC）were more frequent,the duration of mechanical ventilation and oxygen supplementation was longer in patients with ROP（P〈0.05）.Initial serum IGF-1 levels tended to be lower in newborns who developed *** regression analysis revealed that low BW（〈1250 g）,presence of intraventricular hemorrhage（IVH）and formula feeding increased the risk of ***,the scoring system was validated on 107 *** negative predictive values of a score less than 4 were 84.3%,74.7%and 79.8%while positive predictive values were 76.3%,65.5%and71.6%***：In addition to BW〈1250 g and IVH,formula consumption was detected as a risk factor for the development of *** is important for prevention of ROP in preterm infants.

关键词： ROP A predictive score for retinopathy of prematurity by using clinical risk factors and serum insulin-like growth factor-1 levels IVH IGF

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