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Eyelid Wounds: Epidemiological, Clinical and Etiological Aspects

Open Journal of Ophthalmology 2024年第1期14卷 55-62页

作者： Aly Mbara Ka Jean Pierre Diagne Aissatou Aw el.hadji malick sy Soda Mbaye Hawo Madina Diallo Audrey Samra Aboubacry Sadikh Sow Joseph Matar Mass Ndiaye Ousmane Ndiaga Senghor Lamine Ndiaye Mohamed Ndiaye Serigne Sohibou Gaye Papa Amadou Ndiaye Ophthalmology Department of Abass Ndao Hospital Dakar Senegal Ophthalmology Department of Aristide Le Dantec Hospital Dakar Senegal

Purpose: The aim is to show epidemiological, clinical and etiological characteristics of palpebral wounds. Methodology: This was a retrospective study focusing on patients with an eyelid wound, over a 10-year period from 2012 to 2021. We collected and analyzed the data using Excel. Results: The frequency of eyelid wounds was 0.1%. The average age of our patients was 19.38 years with a range of 1 and 62 years. The sex ratio was 3.7. Eighty-one percent of patients lived in Dakar. Fifty-seven percent (57%) of patients consulted less than 24 hours after the trauma and 7% of patients on D1. The circumstances were brawls (11%), domestic accidents (9%), road accidents (6%), and work accidents (6%). We noted 1 case of dog bite. Thirteen patients presented with post-traumatic decreased visual acuity. Involvement of the isolated upper eyelid was noted in 40% of cases and both eyelids in 15% of cases. Involvement of the lacrimal ducts was noted in 17% of cases, and that of the free edge in 21% of cases. Eyelid wounds were associated with eyeball damage in 21% of cases. Various associated lesions were observed. Ninety-one percent of patients received surgical treatment. Three cases of superinfections, 1 case of conjunctival granuloma and 1 case of phthysis of the eyeball with postoperative retinal detachment were noted. Conclusion: Eyelid sores are relatively common in our context. They require rapid surgical treatment in order to preserve the functional and aesthetic prognosis. .

关键词： Eyelid Wounds Epidemiology Clinic Etiologies

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Rhegmatogenous Retinal Detachment in One-Eyed Patients: Therapeutic and Prognostic Challenges

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Open Journal of Ophthalmology 2023年第1期13卷 64-72页

作者： el.hadji malick sy Aïssatou Aw Aly Mbara Ka Jean Pierre Diagne Hawo Madina Diallo Audrey Samra Soda Mbaye Papa Amadou Ndiaye Ophtalmology Department of Abass NDAO Hospital Cheikh Anta Diop University Dakar Senegal

Background: Retinal detachment is a major ophthalmologic emergency. The rhegmatogenous form is the most common and its management is exclusively surgical as soon as possible. This urgency becomes major and absolute when it occurs in a particular monocular vision. Purpose: To analyze the clinical forms of rhegmatogenous retinal detachment (RRD), the results and the complications of their management in monophthalmic patients. Methodology: This was a retrospective and analytical study from June 2007 to December 2019. We included all patients who received a consultation for rhegmatogenous retinal detachment. All patients were seen by at least two posterior segment specialists and all were operated on by the same surgeon. Results: 57 files (57 eyes) were collected with an average age of 44.71 years and a sex ratio of 7.14. The average consultation time is 40.80 days. Patients complained of decreased visual acuity in 96.49% of cases. We had myopia in 49.12% of cases and 91.23% of patients were phakic. Retinal holes were found in 31.58% of our patients and giant tears in 17.54%. The mean retinal detachment extension was 2.52 quadrants and the macula was raised in 32 cases. The average time taken to take charge was 10 days. Detachment surgery was performed in 42 patients with 100% anatomical recovery. Conclusion: Retinal detachment in one-eyed patient is a major ophthalmic emergency. Its management must not suffer from any delay. Post-operative outcomes are relatively similar between the internal and external pathways. In one-eyed patient, silicone can be left alone in the absence of complications.

关键词： Rhegmatogenous Retinal Detachment One-Eyed Patient Intraocular Surgery Episcleral Surgery Post-Operative Results Complications

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Clinical and Therapeutic Aspects of Pediatric Rhegmatogenous Retinal Detachment on Senegalese Black Population

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Open Journal of Ophthalmology 2023年第3期13卷 327-332页

作者： Aïssatou Aw el.hadji malick sy Aly Mbara Ka Jean Pierre Diagne Soda Mbaye Alassane Ba Hawo Madina Diallo Audrey Samra Papa Amadou Ndiaye Ophthalmology Department of Abass NDAO Hospital Cheikh Anta Diop University Dakar Senegal

Background: Rhegmatogenous retinal detachment in children is particular by its severity and challenging treatment. Purpose: To describe the clinical and therapeutic characteristics of pediatric rhegmatogenous retinal detachment. Method: We retrospectively included files of pediatric patients (aged 0 to 15 years), clinically diagnosed with rhematogenous retinal detachment (RRD) between January 2015 and June 2019. The ophthalmological examination was as complete as the age of the patients allowed and a pediatric examination was systematically performed in all children. The data has been processed with Excel 2016 software. Results: 16 eyes of 11 patients were included. The hospital frequency of RRD was 3.37%, with a sex ratio of 1.75 and a mean age of 11.9 years. The average consultation time was 2 months. Contusive eye trauma was reported in 31.25% and myopia in 18.75%. The visual acuity ranged from no light perception to 20/400. The RRD was total in 81.25% and retinal lesions were found in 43.75%, including 25% atrophic holes and tears with lattice degeneration, 12.5% temporal retinal dialysis and one giant tear. Stage B of Proliferative vitreoretinopathy was found in 18.75% and stage C in 56.25%. Scleral buckling was performed in 37.5% and 23G pars plana vitrectomy with silicone oil in 18.75%. The mean duration of follow-up was 24.6 months with anatomical success in 77.7% correlated with functional recovery in 55.5%. The RRD was persistent in one case and a recurrent RRD under silicone was observed in one eye. Two children underwent cataract surgery secondary to vitrectomy, and one case of ocular hypertonia under silicone was noted. Conclusion: Pediatric rhegmatogenous retinal detachment is a severe disease, with essentially traumatic etiology in older children. Delayed diagnosis is a factor in poor prognosis.

关键词： Pediatric Rhegmatogenous Retinal Detachment Trauma Myopia

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The Acute Angle Closure Crisis in Senegalese Melanodermas: Epidemiological and Clinical Aspects of 24 Cases

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Open Journal of Ophthalmology 2023年第4期13卷 407-412页

作者： sy el.hadji malick Aw Aissatou Soda Mbaye Mouhamed Ndiaye Aly Mbara Ka Jean Pierre Diagne Aboubacry Sadikh Sow Joseph Matar Mass Ndiaye Paule Aida Ndoye Papa Amadou Ndiaye AbassNdao University Hospital Center Dakar Senegal Aristide Le Dantec University Hospital Center Dakar Senegal

Introduction Acute angle closure crisis (AACC) is a major ophthalmic emergency. It is a sight-threatening pathology that is very common in women but rarely described in melanodermas. The aim of this work is to investigate the epidemiological and clinical aspects of acute angle closure crisis. Results We collected 24 patient records, totaling 25 eyes. The average age of our patients was 52.04 years, with a male-to-female ratio of 0.6. A family history of glaucoma occurred in 34% of patients. Patients consulted for a painful red eye associated or not with decreased visual acuity (DVA). The condition was bilateral in one patient. The average visual acuity wax 0.34/10e. The cornea was cloudy and the pupil in areflexic mydriasis in all sick eyes. Hypothalamia was present in 72% of eyes and cataracts in 54.16% of cases. The average intraocular press was 44.38 mmHg and the average cup/disc (C/D) was 0.46. Gonioscopy was performed in 7 patients. The fellow eye did not present any abnormalities in 92% of cases. Conclusion The acute angle closure crisis is a rare condition in melanodermas and common in woman. His diagnostic is essentially clinical and completed by gonioscopy which plays a fundamental role. .

关键词： Acute Crisis Angle Hypertonia Gonioscopy

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Study of the Spatio-Temporal Variability of Rainfall in the Northern Region of Senegal

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Journal of Geoscience and Environment Protection 2023年第4期11卷 1-14页

作者： Aichétou Dia Diop Abdoul Karim Mbodji el.hadji Deme malick Wade Mahamat Adoum Moussa Abdoulaye Bouya Diop Younousse Biaye Djiby Sarr Abdou Karim Farota Aboubakary Diakhaby Bouya Diop Laboratoire des Sciences de l’Atmosphère et des Océans Matériaux Energies Dispositifs UGB Saint Louis Senegal Laboratoire D’études et de Recherches en Statistiques et Développement University Gaston Berger (UGB) Saint Louis Senegal Ecole Nationale Supérieure des TIC N’Djamena Tchad

Senegal is a country of the Sahel. In this region, most of the populations live from agro-pastoral activities. The northern zone of Senegal is strongly influenced by river cultures. And the dynamics of the Senegal River are dependent on rainfall. The rainfall in the area is very closely linked to the dynamics of the atmosphere. The study of the spatio-temporal variability of rainfall in the northern region of Senegal requires quality rainfall observation data. It includes the Ferlo and the Senegal River valley, in particular the regions of Louga (department of Linguère included), Saint-Louis (departments of Dagana and Podor included) and Matam. These stations have been defined since Le Borgne (1988). The difficulty of having quality rain observation data can be resolved by using more accessible and good quality satellite data. Using satellite data, namely MSWEP, CRU, TAMSAT, ARC and PERSIANN, we showed the return of precipitation that appeared in 2000 and the unimodal cycle of precipitation in our study area. These data were validated using the correlation coefficient, the bias, the RMSE and the Nash index with observation data from the Regional Study Center for the Improvement of Adaptation to Drought (CERASS). The CRU data is then retained. Thus, this study made it possible to show the zonal distribution of rainfall in the northern zone of Senegal.

关键词： Rainfall in the Northern Region of Senegal Variability of Rainfall Satellite Data The Zonal Distribution of Rainfall

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Evaluation of Kidney Function in Patients with COVID-19 at the Epidemiological Treatment Centre in CHNU Fann

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Advances in Biological Chemistry 2023年第1期13卷 17-24页

作者： Thioune Ndeye Mareme Kandji Pape Matar Djite Moustapha Barry Nene Oumou Kesso Zaamoumi Bassma Kane Mame Coumba Diagne Bineta Mbacke Mame Ndoumbé Sagne René Ngor Ndour el.hadji malick Gueye-Tall Fatou Lopez-Sall Philomene Cisse Aynina Diop Pape Amadou Gueye Papa Madieye Laboratory of Biochemistry-Hematology National University Hospital of Fann Dakar Senegal Laboratory of Pharmaceutical Biochemistry Faculty of Medicine Pharmacy Cheikh Anta Diop University Dakar Senegal

Alteration of renal function during SARS-CoV-2 infection is frequent and is associated with excess mortality. It is multifactorial, involving mechanisms more specific to COVID-19: viral invasion, endothelitis and thrombosis, activation of the renin-angiotensin-aldosterone system, and elevation of pro-inflammatory cytokines. Thus, the objective of this work was to assess renal function in patients with moderate and severe forms of COVID-19. This was a prospective cross-sectional study of patients with COVID-19. The parameters studied were age, sex, uremia, creatinine and glomerular filtration rate (GFR). All biological parameters were measured with the A15 Biosystems automated system (Barcelona, Spain) and the GFR was calculated according to the MDRD formula. Data processing was carried out with the SPSS (Statistical Package for Social Sciences) software version 23. Our study population consisted of 192 subjects with COVID-19, of which 111 were moderate and 81 were severe. The mean age of our subjects was 60 years and a sex ratio of 1.02. GFR assessment showed that 28% of the population had a lowered GFR (2). Analysis of the results according to the clinical forms showed frequencies of 19% of disturbance of renal function for the moderate forms against 40% for the severe forms. Impaired renal function appears to be frequent in patients with severe SARS-CoV-2 infection and is associated with a bad prognosis. Any patient hospitalized with SARS-CoV-2 should benefit from an initial nephrological assessment which could be used as a marker to dictate the prognosis of the severity of COVID-19.

关键词： COVID-19 CTE GFR Renal Function SARS-CoV-2

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Disparities in Dental Caries among Students in Senegalese Koranic School: Epidemiological Study in Daara of Koki

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Open Journal of Epidemiology 2022年第2期12卷 125-133页

作者： Serigne Ndame Dieng Amadou Dieng Mbathio Diop el Hadj malick Diouf Aida Kanouté Massamba Diouf Cheikh Mbaké Lô Daouda Faye Public Health Service Institute of Dentistry and Stomatology Faculty of Medicine Pharmacy and Odonto-Stomatology Cheikh Anta Diop University Dakar Senegal Sangalkam Health District Dakar Medical Region Ministry of Health and Social Action Dakar Senegal

Background: School is a space where children are exposed to the social and psychosocial environment that can affect their health. In Senegal, the prevalence of dental caries is high in classic schools according to fragmented data, and unknown in the koranic school (Daaras). Objective: The objective is to describe the disparity of dental caries in the schoolchildren (talibes) of Daara of Koki. Method: A cross-sectional study was carried out on 400 talibes aged 7 to 12 years. Dental caries and socio-demographic data were, respectively, collected by clinical examination and questionnaire. Results: The sex ratio was 9, the mean age of 9.9 ± 1.5 years and the mean length of stay in the Daara was 2.3 ± 1.1 years. The prevalence of dental caries was 47.4%. The average mixed DFMT index was 1.1 ± 1.5. The prevalence was 51.2% among boys, 60% among eight-year-old children and 37.4% among twelve-year-old children. By length of stay, the prevalence was 52.9% at the start and 22.2% at the end with a significant downward trend (p Conclusion: The study showed an unequally distributed of caries among talibes of Koki’s Daara. She suggests that oral health promotion policies are needed in Koranic schools and must rely on koranic teachers.

关键词： Dental Caries Students Koranic School

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Thermoresistant, Ethanol-Resistant and Acid-Resistant Properties of Acetic Acid Bacteria Isolated from Fermented Mango Alcohol

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Advances in Microbiology 2022年第4期12卷 177-191页

作者： Mariama Ciré Kourouma malick Mbengue Ndèye Coumba Daga Sarr Khady Sarr Coumba Touré Kane Laboratory of Applied Microbiology and Industrial Engineering (MAGI) Ecole Supérieure Polytechnique (ESP) Université Cheikh Anta Diop Dakar-Fann Senegal Université Sine Saloum el Hadj Ibrahima Niass (USSEIN) Kaolack Senegal

Vinegar production is seriously affected by the sensitivity of acetic acid bacteria (AAB) to high temperature, high ethanol concentrations, and high acetic acid concentrations. The aim of this study was to investigate the thermo-ethanol-acid tolerance characters of five AAB strains (VMA1, VMA5, VMA7, VMAM, VMAO) previously isolated from fermented mango alcohol and belonging to Gluconoacetobacter genera. As result, the five AAB strains exhibited good growth and acid production at temperatures up to 45°C;they could tolerate and produce acetic acid at ethanol concentrations up to 20% (v/v). In addition, the studied strains showed growth at acetic acid concentrations up to 4.5% (w/v). Strains VMA7 and VMAO showed the highest resistance properties: they demonstrated acid production at 50°C and VMAO could even grow at 60°C;they tolerated and produced acetic acid at 25% (v/v) ethanol concentration;they showed resistance to acetic acid concentrations up to 6% (w/v). Considering all these properties, the use of these strains would seriously contribute to improving the quality of the vinegar produced and help to reduce the cooling water feeds in vinegar production especially in hot countries in the context of global warming.

关键词： Vinegar Acetic Acid Bacteria Thermotolerant Ethanol-Tolerant Acid-Tolerant

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Association between Uric Acid and Metabolic syndrome in Homozygous Sickle Cell Patients

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Advances in Biological Chemistry 2021年第3期11卷 142-148页

作者： Kandji Pape Matar Djite Moustapha Barry Nene Oumou Kesso Sagne Rene Ngor Thioune Ndeye Mareme Mbacke Ndoumbé Mame Ndour el.hadji malick Gueye-Tall Fatou Lopez-Sall Philomene Cisse Aynina Diop Pape Amadou Gueye Papa Madieye Laboratory of Biochemistry-Hematology National University Hospital of Fann Dakar Senegal Laboratory of Pharmaceutical Biochemistry Faculty of Medicine Pharmacy Cheikh Anta Diop University Dakar Senegal

The objective of this study was to assess the association between uric acid and the metabolic syndrome and its components in homozygous sickle cell patients. This is a prospective case/control study of sickle cell SS patients. Each patient was matched to a control of the same sex and age ± 2 years. In our framework, we used the criteria for defining metabolic syndrome according to International Diabetes Federation (IDF) 2009. Assay of all biological parameters was performed with the ARCHITECT ci4100, Abbot (Chicago, Illinois, USA). Data were collected with Excel 2016 software and statistical analysis was done using XLSTAT 2019 software. Student’s T test was used to compare means and a p-

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Positive Surgical Margins (PSM) after Open Retropubic Radical Prostatectomy: Evaluation of Patient Survival

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Open Journal of Urology 2021年第7期11卷 282-288页

作者： Babacar Sine Abdoulaye Ndiath Ndéye Aissatou Bagayogo Alioune Sarr Amath Thiam Cyrille Ze Ondo Ousmane Sow el.hadji malick Diaw Moussa Séne Babou Sakho Cheikh Bécaye Gassama Ibrahima Ngom Yaya Sow Babacar Diao Alain Khassim Ndoye Urology Andrology Department of Aristide Le Dantec Hospital Dakar Sénégal Urology Andrology Department of Ouakam Military Hospital Dakar Sénégal

Background: Many patients who have had radical prostatectomy for prostate cancer may present with microscopic extraprostatic extension of the disease. Positive surgical margins are a common pathological finding in this subgroup of patients. To report the epidemiological, clinical and therapeutic aspects of PSM after radical prostatectomy (RP) and to evaluate the follow-up of patients. Patients and methods: A single-center retrospective descriptive study of patients who underwent radical prostatectomy between June 1, 2004 and December 31, 2019 was conducted. Patients who had radical prostatectomy with PSM on pathology report were included. The parameters studied were age, initial prostate specific antigen (PSA), Gleason and International Society of Uropathology (ISUP) scores, cTNM and pTNM stages, operative technique, PSA levels after surgery, adjuvant treatment and patient survival. Results: Eighty-six (86) radical prostatectomies were performed. PSM was found in 23 patients (26.7%). The mean age of the patients was 63.7 ± 6.1 years. The mean preoperative total PSA was 31.5 ng/mL (6.31 - 146 ng/mL). Prostate biopsy showed only prostatic adenocarcinoma. Thoracic-abdominopelvic CT was performed in all patients. Prostate cancers were found at the localized stage in 12 patients and locally advanced in 11 patients. A classification adjustment was obtained after pathological examination of the surgical specimen. The ISUP score 3 and 1 on the surgical specimen were in the majority with 9 and 7 patients respectively. After the recurrence, all patients who consented received hormone therapy, which was either medical with Goserelin and Triptorelin (7 patients) or surgical with testicular pulpectomy (1 patient). PSA was undetectable (Conclusion: RP with PSM is a fai

关键词： Prostate Cancer Surgical Margins Survival

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