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Fatal Legionella pneumophila serogroup 1 pleural empyema:A case report

World Journal of Critical Care Medicine 2019年第6期8卷 99-105页

作者： Francois Maillet Nicolas Bonnet Typhaine Billard-Pomares Fatma el Alaoui Magdoud Yacine Tandjaoui-Lambiotte Intensive Care Unit Avicenne HospitalAssistance Publique-Hoitaux de ParisBobigny 93000France Paris XIII University Bobigny 93000France Microbiology Department Avicenne HospitalAssistance Publique H-oitaux de ParisBobigny 93000France Microbiology Department Jean Verdier HospitalAssistance Publique-Hoitaux de ParisBondy 93140France

BACKGROUND Legionella pneumophila(***)is a gram-negative intracellular bacillus composed of sixteen different *** is mostly known to cause pneumonia in individuals with known risk factors as immunocompromised status,tobacco use,chronic organ failure or age older than 50 *** parapneumonic pleural effusion is frequent in legionellosis,pleural empyema is very *** this study,we report a case of fatal pleural empyema caused by *** serogroup 1 in an 81-year-old man with multiple risk *** SUMMARY An 81-year-old man presented to the emergency with a 3 wk dyspnea,fever and left chest *** previous medical conditions were chronic lymphocytic leukemia,diabetes mellitus,chronic kidney failure,hypertension and hyperlipidemia,without tobacco *** X-ray and comouted tomographyscan confirmed a large left pleural effusion,which puncture showed a citrine exudate with negative standard bacterial *** intravenous cefotaxime antibiotherapy,patient’s worsening condition after 10 d led to thoracocentesis and evacuation of 2 liters of *** patient progressively developed severe hypoxemia and multiorgan failure *** patient was treated by antibiotherapy with cefepime and amikacin and with adequate symptomatic shock treatment,but died of uncontrolled *** next day,cultures of the surgical pleural liquid samples yielded *** serogroup 1,consistent with the diagnosis of pleural *** *** should be considered in patients with multiple risk factors and undiagnosed pleural empyema unresponsive to conventional antibiotherapy.

关键词： Legionella pneumophila serogroup 1 Legionellosis Legionnaire’s disease Pleural empyema Case report

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Cystic Lymphangioma on the Floor of the Oral Cavity Extending to the Submandibular Region in Adult Patients

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International Journal of Otolaryngology and Head & Neck Surgery 2020年第4期9卷 133-140页

作者： Nadia M’jahad Najib Benmansour Abdelouahid Taleuan Akammar Amal Mustapha Maaroufi Mohamed Nourredine el Alami Faculty of Medicine and Pharmacy Sidi Mohammed Benabdellah University Fez Morocco Department of Otorhinolaryngology (ENT) and Headneck Surgery CHU Hassan II Fez Morocco Department of Radiology CHU Hassan II Fez Morocco

Lymphatic malformation (ML), formerly called cystic lymphangioma is a benign hamartomatous tumor of lymphatic vessels. The onset of lymphangiomas is either at birth (60% to 70%) or up to two years of age (90%) and rare in adults. These malformations can occur in any region of the body, Lymphangiomas have marked predilection for the head and neck region (50% - 70%). The most common location in the mouth is the dorsum of tongue. If the positive diagnosis is generally easy, the therapeutic management remains controversial. We report the clinical case of a 23-year-old adult patient with cystic lymphangioma on the floor of the oral cavity extending gradually to the right submandibular region. The clinically suspected tumor was thoroughly explored using tomodensitometry. The treatment consisted of complete resection by a cervicotomy with histological examination confirming the macroscopic diagnosis of cystic lymphangioma. Follow-up at 3 years showed no recurrence.

关键词： Cystic Lymphangioma Oral Cavity The Floor of the Oral Cavity Submandibular Regio

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Hybrid Genetic Algorithm with K-Means for Clustering Problems

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Open Journal of Optimization 2016年第2期5卷 71-83页

作者： Ahamed Al Malki Mohamed M. Rizk M. A. el-Shorbagy A. A. Mousa Department of Mathematics and Statistic Faculty of Science Taif University Taif Saudi Arabia Department of Mathematics Faculty of Science Menoufia University Al Minufya Egypt Department of Basic engineering sciences Faculty of Engineering Menoufia University Al Minufya Egypt

The K-means method is one of the most widely used clustering methods and has been implemented in many fields of science and technology. One of the major problems of the k-means algorithm is that it may produce empty clusters depending on initial center vectors. Genetic Algorithms (GAs) are adaptive heuristic search algorithm based on the evolutionary principles of natural selection and genetics. This paper presents a hybrid version of the k-means algorithm with GAs that efficiently eliminates this empty cluster problem. Results of simulation experiments using several data sets prove our claim.

关键词： Cluster Analysis Genetic Algorithm K-Means

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The Late Neoproterozoïc Continental Tholeiitic Basalts of the Toubkal Inlier (Western High-Atlas, Morocco): A Post-Pan-African Rifting Witness in the Northern Margin of the West African Craton

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Open Journal of Ecology 2016年第8期6卷 509-516页

作者： Ghalem Zahour Hassan el Hadi Abdelfatah Tahiri Youssef Zerhouni Saida Alikouss Rachid Zahour Aicha Reddad Laboratory of Paleobelts Geodynamic Sciences Faculty of Ben M’sik Hassan II University of Casablanca Casablanca Morocco Geology and Remote Sensing Laboratory URAC46 Mohammed V University of Rabat Scientific Institute Rabat Morocco Laboratory of Géosciences Science and Techniques Faculty Guéliz Cadi Ayyad University Marrakech Morocco

The late Neoproterozoïc Toubkal inlier (Ancient Massif of the High-Atlas, Morocco) contains two igneous basaltic series (Tircht and Sidi Chamharouch). Investigated rocks display characteristics of within-plate continental tholeiitic and are similar to rocks originated in orogenic contexts. The geochemical results allow the assumption that subduction active processes are indirectly responsible for the genesis of theses rocks. The orogenic signature is linked probably to a Pan-African magmatic source previously metasomatized in the northern margin of the West African Craton.

关键词： Toubkal Inlier Late Neoproterozoïc Continental Tholeiites Rift West African Craton

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Liver fibrosis recognition using multi-compression elastography technique

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Journal of Biomedical Science and Engineering 2013年第11期6卷 1034-1039页

作者： Ashraf Ali Wahba Nagat Mansour Mohammed Khalifa Ahmed Farag Seddik Mohammed Ibrahim el-Adawy Faculty of Engineering Biomedical Engineering Department Helwan University Helwan Cairo Egypt

Liver fibrosis recognition is an important issue in diagnostic imaging. The accurate estimation of liver fibrosis stages is important to establish prognosis and to guide appropriate treatment decisions. Liver biopsy has been for many years the reference procedure to assess histological definition for liver diseases. But biopsy measurement is an invasive method besides it takes large time. So, fast and improved methods are needed. Using elastography technology, a correlation technique can be used to calculate the displacement of liver tissue after it has suffered a compression force. This displacement is related to tissue stiffness, and liver fibrosis can be classified into stages according to that displacement. The value of compression force affects the displacement of tissue and so affects the results of the liver fibrosis diagnosing. By using finite element method, liver fibrosis can be recognized directly within a short time. The proposed work succeeded in recognizing liver fibrosis by a percent reached in average to 86.67% on a simulation environment.

关键词： Liver Fibrosis Liver Cirrhosis Liver Inflammation Hook’s Law Correlation elastography and Liver Fibrosis Recognition

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Local wavelet-based filtering of electromyographic signals to eliminate the electrocardiographic-induced artifacts in patients with spinal cord injury

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Journal of Biomedical Science and Engineering 2013年第7期6卷 1-13页

作者： Matthew Nitzken Nihit Bajaj Sevda Aslan Georgy Gimel’farb Ayman el-Baz Alexander Ovechkin BioImaging Laboratory Bioengineering Department University of Louisville Louisville USA Department of Computer Science The University of Auckland Auckland New Zealand Department of Neurological Surgery University of Louisville Louisville USA Frazier Rehab Institute Louisville USA Department of Neurological Surgery University of Louisville Louisville USA Frazier Rehab Institute Louisville USA

Surface electromyography (EMG) is a standard method used in clinical practice and research to assess motor function in order to help with the diagnosis of neuromuscular pathology in human and animal models. EMG recorded from trunk muscles involved in the activity of breathing can be used as a direct measure of respiratory motor function in patients with spinal cord injury (SCI) or other disorders associated with motor control deficits. However, EMG potentials recorded from these muscles are often contaminated with heart-induced electrocardiographic (ECG) signals. elimination of these artifacts plays a critical role in the precise measure of the respiratory muscle electrical activity. This study was undertaken to find an optimal approach to eliminate the ECG artifacts from EMG recordings. Conventional global filtering can be used to decrease the ECG-induced artifact. However, this method can alter the EMG signal and changes physiologically relevant information. We hypothesize that, unlike global filtering, localized removal of ECG artifacts will not change the original EMG signals. We develop an approach to remove the ECG artifacts without altering the amplitude and frequency components of the EMG signal by using an externally recorded ECG signal as a mask to locate areas of the ECG spikes within EMG data. These segments containing ECG spikes were decomposed into 128 sub-wavelets by a custom-scaled Morlet Wavelet Transform. The ECG-related subwavelets at the ECG spike location were removed and a de-noised EMG signal was reconstructed. Validity of the proposed method was proven using mathematical simulated synthetic signals and EMG obtained from SCI patients. We compare the Rootmean Square Error and the Relative Change in Variance between this method, global, notch and adaptive filters. The results show that the localized wavelet-based filtering has the benefit of not introducing error in the native EMG signal and accurately removing ECG artifacts from EMG signals.

关键词： EMG De-Noising ECG Local Wavelet Filtering

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A Finite element Model for Recognizing Breast Cancer

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Journal of Biomedical Science and Engineering 2014年第5期7卷 296-306页

作者： Ashraf Ali Wahba Nagat Mansour Mohammed Khalifa Ahmed Farag Seddik Mohammed Ibrahim el-Adawy Faculty of Engineering Biomedical Engineering Department Helwan University Cairo Egypt Radio-Diagnosis National Cancer Institute Cairo University Cairo Egypt

Breast cancer recognition is an important issue in elastography diagnostic imaging. Breast tumor biopsy has been for many years the reference procedure to assess histological definition for breast diseases. But biopsy measurement is an invasive method besides it takes larger time. So, fast and improved methods are needed. Using elastography technology, a digital image correlation technique can be used to calculate the displacement of breast tissue after it has suffered a compression force. This displacement is related to tissue stiffness, and breast cancer can be classified into benign or malignant according to that displacement. The value of compression force affects the displacement of tissue, and then affects the results of the breast cancer recognition. Finite element method was being used to simulate a model for the breast cancer as a phantom to be used in measurements and study of breast cancer diagnosis. The breast cancer using this phantom can be recognized within a short time. The proposed work succeeded in recognizing breast tumor phantom by an average correct recognition ratio CRR of about 94.25% on a simulation environment. The strain ratio SR for benign and malignant models is also computed. The result of the simulated breast tumor model is compared with real data of 10 lesion cases (6 benign and 4 malignant). The coefficient of variation CV between the simulated SR and the SR using real data reaches to about 5% for benign lesions and 4.78% for malignant lesions. The results of CRR and CV in this proposed work assure that the proposed breast cancer model using finite element modeling is a robust technique for breast tumor simulation where the behavior of real data of breast cancer can be predicted.

关键词： Breast Cancer Digital Image Correlation Ultrasound elastography Strain Analysis Breast Cancer Diagnosis

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The Inhibitive Effect of 3-Methyl 4-Amino 1,2,4 Triazole on the Corrosion of Copper-Nickel 70 - 30 in NaCl 3% Solution

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Materials Sciences and Applications 2011年第9期2卷 1260-1267页

作者： Tayeb Chieb Kamel Belmokre Mohammed Benmessaoud Sidi el Hassane Drissi Najat Hajjaji Abdellah Srhiri 不详

The effect of 3-methyl 4-amino 1,2,4 triazole (MATA) on the corrosion behaviour of copper-nickel 70 - 30 (Monel) in NaCl 3% solution is investigated at 298 K by weight loss measurements, potentiodynamic polarisation and impedance spectroscopy (EIS′) methods. Preliminary screening of the inhibition efficiency (ECR) was carried out with using weight- loss measurements. Polarization measurements showed that the organic compound investigated is mixed type inhibitor (it acts on the cathodic and the cathodic reactions), inhibiting the corrosion of Monel by blocking the active sites of the metal surface. Changes in the impedance parameters charge transfer resistance (Rct) and double layer capacitance (Cdl) are related to adsorption of organic inhibitor of the metal surface, leading to the formation of protective film, which grows with increasing exposure time. Inhibition efficiencies obtained from cathodic Tafel plots, gravimetric and EIS methods are in good agreement. Results obtained shows that the (MATA) is good inhibitor for copper – nickel, and its efficiency reaches more than 95% at 60 ppm after 30 mn of immersion.

关键词： Copper-Nickel Triazole Inhibitor Efficiency Polarisation Impedance

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Relation between the Actual and Estimated Maximum Ground Level Concentration of Air Pollutant and Its Downwind Locations

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Open Journal of Air Pollution 2020年第2期9卷 27-35页

作者： Khaled S. M. Essa Soad M. Etman Maha S. el-Otaify Mathematics and Theoretical Physics Department NRC/AEA Cairo Egypt

In this work we used the Gaussian plume model to calculate the actual maximum ground level concentration (MGLC) of air pollutant and its downwind location by using different systems of dispersion parameters and for different stack heights. An approximate formula for the prediction of downwind position that produces the MGLC of a pollutant based on the Gaussian formula was derived for different diffusion parameters. The derived formula was used to calculate the approximate MGLC. The actual and estimated values are presented in tables. The comparison between the actual and estimated values was investigated through the calculation of the relative errors. The values of the relative errors between the actual and estimated MGLC lie in the range from: 0 to 70.2 and 0 to 1.6 for Pasquill Gifford system and Klug system respectively. The errors between the actual and estimated location of the MGLC lies in the range from: 0.2 to 227 and 0.7 to 9.4 for Pasquill Gifford system and Klug system respectively.

关键词： Gaussian Plume Model Actual and Estimated Values Relative Errors

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The Ciliate Protist <i>Tetrahymena pyriformis</i>as a Cellular Adhesion Model for the Pathogenic Bacterium <i>Staphylococcus aureus</i>

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Advances in Bioscience and Biotechnology 2017年第12期8卷 491-507页

作者： Bouchra el Khalfi Mohammed Benlahfid Sofia Jarmouni Nezha Senhaji Aurelio Serrano Delgado Abdelaziz Soukri Laboratory of Physiopathology Genetics Molecular and Biotechnology (PGMB) Faculty of Sciences Ain Chock Research Center: Health & Biotechnology University Hassan II of Casablanca Casablanca Morocco Laboratory of Genetic and Molecular Pathology (LGPM) Medical School Hassan II University Casablanca Morocco Institute of Biochemistry Vegetal and Photosynthesis (IBVF-CSIC University of Seville) Seville Spain

Staphylococcus aureus is one of the main pathogenic agents responsible for nosocomial and community-acquired bacterial infections. The pathogenicity of this Gram-positive bacterium is ensured by its different adhesion factors. Collagen and the extracellular glycoprotein adhesin are among the Staphylococcus most important virulence factors. It has been shown that most of the S. aureus strains carry the ica operon, responsible for biofilm production. However, the coexpression of the icaA and the icaD genes is necessary for complete biofilm synthesis. The aim of our study was to study a collection of 15 clinical strains of S. aureus from different sources for the presence of can and icaD genes coding intercellular adhesion proteins. We also intended to estimate the strains’ ability to form biofilms by the red Cong method and to test the adhesion ability of S. aureus to the ciliated protist Tetrahymena pyriformis, which we used as a novel cellular adhesion model. Finally, we checked the adhesion’s inhibition capacity of some plants extracts. The molecular detection of adhesion genes revealed that 80% of strains are cna positive, and 73% are icaD positive. Qualitative biofilm production of S. aureus revealed that 66.6% of strains were slime producers. The adhesion test revealed that 20% of strains are strongly adhering to T. pyriformis and that the Clematis cirrhosa extract has an anti-adhering effect of S. aureus to the ciliate T. pyriformis.

关键词： Staphylococcus aureus Adhering Genes (can and icaD) Tetrahymena pyriformis Biofilm Production Plant Extract Anti-Adhesion Effect

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