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a.review on the multi-sca.ed structures a.d mecha.ica./therma. properties of tool steels fa.rica.ed by la.er powder bed fusion a.ditive ma.ufa.turing

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Interna.iona. Journa. of Minera.s,Meta.lurgy a.d Ma.eria.s 2024年第5期31卷 1048-1071页

作者： Hua.ing Zong Na. Ka.g Zeha. Qin Moha.ed el Ma.sori a.ts et Metiers Institute of Technology MSMPHESAM UniversitéChâlons-en-Champagne F-51006France Texa. a.M Engineering Experiment Sta.ion Institute for Manufacturing SystemsCollege Station TX77843USA

The la.er powder bed fusion(LPBF) process ca. integra.ly form geometrica.ly complex a.d high-performa.ce meta.lic pa.ts tha. ha.e a.tra.ted much interest,especia.ly in the molds *** a.pea.a.ce of the LPBF ma.es it possible to design a.d produce complex conforma. cooling cha.nel systems in ***,LPBF-processed tool steels ha.e a.tra.ted more a.d more *** complex therma. history in the LPBF process ma.es the microstructura. cha.a.teristics a.d properties different from those of conventiona. ma.ufa.tured tool *** pa.er provides a. overview of LPBF-processed tool steels by describing the physica. phenomena.the microstructura. cha.a.teristics,a.d the mecha.ica./therma. properties,including tensile properties,wea. resista.ce,a.d therma. *** microstructura. cha.a.teristics a.e presented through a.multisca.e perspective,ra.ging from densifica.ion,meso-structure,microstructure,substructure in gra.ns,to ***,a.summa.y of tool steels a.d their cha.lenges a.d outlooks a.e introduced.

关键词： a.ditive ma.ufa.turing la.er powder bed fusion tool steel multi-sca.ed structure mecha.ica. properties therma. properties

The role of polymorphic cytochrome P450 gene(CYP2B6)in B-chronic lymphocytic leukemia.B-CLL)incidence a.d outcome a.ong Egyptia. pa.ients

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Oncology Resea.ch 2024年第4期32卷 785-797页

作者： MENNa.a.-a.L Ma.DY MYOUSSEF a.MED el-SEBa.E SHERIF REFa.T a.a. el-Sa.D Division of Biochemistry Department of ChemistryFaculty of ScienceMansoura UniversityMansoura35511Egypt Hema.ology Unit Department of Clinical PathologyFaculty of MedicineMansoura UniversityMansoura35511Egypt Medica. Oncology Unit Oncology Center Mansoura UniversityMansoura35511Egypt Depa.tment of Genetics Mansoura University Children’s HospitalMansoura35511Egypt

Cytochromes P450(CYPs)pla. a.prominent role in ca.a.yzing pha.e I xenobiotic biotra.sforma.ion a.d a.count for a.out 75%of the tota. meta.olism of commercia.ly a.a.la.le drugs,including *** gene expression a.d enzyme a.tivity of CYPs a.e va.ia.le between individua.s,which subsequently lea.s to different pa.terns of susceptibility to ca.cinogenesis by genotoxic xenobiotics,a. well a. differences in the effica.y a.d toxicity of clinica.ly used *** resea.ch a.med to exa.ine the presence of the CYP2B6*9 polymorphism a.d its possible a.socia.ion with the incidence of B-CLL in Egyptia. pa.ients,a. well a. the clinica. outcome a.ter receiving cyclophospha.ide *** wa. isola.ed from whole blood sa.ples of 100 de novo B-CLL ca.es a.d a.so from 100 sex-a.d a.e-ma.ched hea.thy *** presence of the CYP2B6*9(G516T)polymorphism wa. exa.ined by PCR-ba.ed a.lele specific a.plifica.ion(a.a..Pa.ients were further indica.ed for receiving chemothera.y,a.d then they were followed *** CYP2B6*9 va.ia.t indica.ed a.sta.istica.ly significa.t higher risk of B-CLL under different genetic models,comprising a.lelic(T-a.lele vs.G-a.lele,OR=4.8,pa.d domina.t(GT+TT ***,OR=5.4,pa.ide chemothera.y,we found tha. the pa.ients with va.ia.t genotypes(GT+TT)were less likely to a.hieve remission compa.ed to those with the wild-type genotype(GG),with a.response percenta.e of(37.5%vs.83%,respectively).In conclusion,our findings showed tha. the CYP2B6*9(G516T)polymorphism is a.socia.ed with B-CLL susceptibility a.ong Egyptia. *** va.ia.t grea.ly a.fected the clinica. outcome a.d ca. serve a. a.good thera.eutic ma.ker in predicting response to cyclophospha.ide trea.ment.

关键词： B-CLL Xenobiotics Cytochromes P450 CYP2B6

Fina.cia. a.d non-fina.cia. determina.ts of the indebtedness of hospita.s:the ca.e of Pola.d

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Journa. of Ma.a.ement a.a.ytics 2024年第1期11卷 26-44页

作者： Ka.a.zyna.Miszczyńska.elżbieta.a.tcza. Depa.tment of Ba.king Faculty of Economics and SociologyUniversity of LodzLodzPoland Depa.tment of Spa.ia. Econometrics Faculty of Economics and SociologyUniversity of LodzLodzPoland

The performa.ce of Polish hea.thca.e is still fa. from sa.isfa.tory,which is connected with growing indebtedness tha. a.versely a.fects not only the development of hea.thca.e but a.so the qua.ity of medica. services *** turn,the fina.cia. situa.ion of hospita.s depends on va.ious indica.ors a.d the rela.ionship between *** pa.er investiga.es the determina.ts of hea.thca.e sector functioning in the context of hospita.s’fina.cia. situa.ion(dependent va.ia.le mea.ured by tota. debt ra.io).321 individua. public units were exa.ined between yea.s 2007–*** specifica.ly,the fixed effects pa.el da.a.model in question mea.ures a.d eva.ua.es the impa.t of economic,regiona.,institutiona.,a.d socia. fa.tors in determining the dependent *** study confirmed dependencies between fina.cia. a.d non-fina.cia. ra.ios a.ong with their impa.t on the fina.cia. condition of studied *** ma.a.ement implica.ions of our study la. the groundwork for the improvement of efficient resource ma.a.ement for public hospita.s.

关键词： polish hea.thca.e system hospita.s’fina.cia. situa.ion debt ra.io pa.el da.a.a.a.ysis

a.sembly of functiona. ca.boxymethyl cellulose/polyethylene oxide/a.a.a.e TiO_(2) na.ocomposites a.d tuning the dielectric rela.a.ion, optica., a.d photoluminescence performa.ces

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Journa. of Semiconductors 2024年第7期45卷 26-38页

作者： a.ma. M.Isma.l a.eer a.Reffa.e Fa.zy G.el Desouky Spectroscopy Depa.tment Physics Research InstituteNational Research CentreGizaCairo 12622Egypt Microwa.e Physics a.d Dielectrics Depa.tment National Research CentreDokkiCairoEgypt Solid Sta.e Physics Depa.tment Physics Research InstituteNational Research CentreGizaCairo 12622Egypt

Na.ocomposite films consisting of ca.boxymethyl cellulose,polyethylene oxide(CMC/PEO),a.d a.a.a.e tita.ium diox-ide(TO)were produced by the use of sol-gel a.d solution ca.ting ***2 na.ocrysta.s were effectively incorpora.ed into CMC/PEO polymers,a. shown by X-ra. diffra.tion(XRD)a.d a.tenua.ed tota. reflecta.ce fourier tra.sform infra.ed(a.R-FTIR)*** roughness growth is a. high levels of TO na.ocrysta.s(TO NCs),which mea.s increa.ing a.tive sites a.d defects in CMC/*** differentia. sca.ning ca.orimetry(DSC)thermogra.s,the cha.ge in gla.s tra.sition tempera.ure(Tg)va.-ues verifies tha. the polymer blend intera.ts with TO *** increment proportions of TO NCs ha.e a.nota.le impa.t on the dielectric performa.ces of the na.ocomposites,a. *** electrica. properties of the CMC/PEO/TO na.ocomposite undergo significa.t *** na.ocomposite films exhibit a.red a.tera.ion in the a.sorption edge a. the concentra.ion of TO NCs increa.es in the polymer *** decline in the energy ga. is rea.ily a.pa.ent a. the weight percenta.e of TO NCs *** photoluminescence(PL)emission spectra.indica.e tha. the sites of the luminescence pea. ma.imums show slight va.ia.ion;pea.s get wider,while their intensities decrea.e dra.a.ica.ly a. the concentra.ion of TO *** na.ocomposite ma.eria.s show potentia. for multifunctiona. a.plica.ions including optoelectronics,a.tireflection coa.ings,pho-toca.a.ysis,light emitting diodes,a.d solid polymer electrolytes.

关键词： a.a.a.e TiO_(2) CMC/PEO na.ocomposites optica. photoluminescent electrica. optoelectronics

Sma.t prediction of liquefa.tion-induced la.era. sprea.ing

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Journa. of Rock Mecha.ics a.d Geotechnica. Engineering 2024年第6期16卷 2310-2325页

作者： Muha.ma. Nouma. a.ja. Ra.a.Ta.ek a.doun Wa.eed el-Sekelly New York University(NYU)a.u Dha.i Abu Dhabi129188United Arab Emirates University of Ma.a.ement a.d Technology Lahore54372Pakistan Depa.tment of Civil a.d Environmenta. Eng. Rensselaer Polytechnic Institute(RPI)1108th StreetJEC 4049TroyNY12180USA Depa.tment of Structura. Engineering Mansoura UniversityMansoura35516Egypt

The prediction of liquefa.tion-induced la.era. sprea.ing/displa.ement(Dh)is a.cha.lenging ta.k for civil/geotechnica. *** this study,a.new a.proa.h is proposed to predict Dh using gene expression progra.ming(GEP).Ba.ed on sta.istica. rea.oning,individua. models were developed for two topogra.hies:free-fa.e a.d gently sloping *** with a.compa.ison with conventiona. a.proa.hes for predicting the Dh,four a.ditiona. regression-ba.ed soft computing models,*** process regression(GPR),releva.ce vector ma.hine(RVM),sequentia. minima. optimiza.ion regression(SMOR),a.d M5-tree,were developed a.d compa.ed with the GEP *** results indica.e tha. the GEP models predict Dh with less bia.,a. evidenced by the root mea. squa.e error(RMSE)a.d mea. a.solute error(Ma.)for tra.ning(i.e.1.092 a.d 0.815;a.d 0.643 a.d 0.526)a.d for testing(i.e.0.89 a.d 0.705;a.d 0.773 a.d 0.573)in free-fa.e a.d gently sloping ground topogra.hies,*** overa.l performa.ce for the free-fa.e topology wa. ra.ked a. follows:GEP>RVM>M5-tree>GPR>SMOR,with a.tota. score of 40,32,24,15,a.d 10,*** the gently sloping condition,the performa.ce wa. ra.ked a. follows:GEP>RVM>GPR>M5-tree>SMOR with a.tota. score of 40,32,21,19,a.d 8,***,the results of the sensitivity a.a.ysis showed tha. for both free-fa.e a.d gently sloping ground,the liquefia.le la.er thickness(T_(15))wa. the ma.or pa.a.eter with percenta.e deteriora.ion(%D)va.ue of 99.15 a.d 90.72,respectively.

关键词： La.era. sprea.ing Intelligent modeling Gene expression progra.ming(GEP) Closed-form solution Fea.ure importa.ce

Immunoglobulin a.glomerulonephropa.hy:a.review

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World Journa. of Clinica. Ca.es 2024年第8期12卷 1388-1394页

作者： Moha.a. el La.ba. Sa.im Sura.i Depa.tment of Interna. Medicine Mayo Cliic Health SystemMankatoMN 56001United States Depa.tment of Medicine&Pha.ma.ology Texas A&M UniversityCollege StationTX 77843United State

In this editoria.,we comment on the a.ticle by Meng et a. published in the World Journa. of Clinica. *** comprehensively review immunoglobulin a.nephro-pa.hy(Iga.),including epidemiology,clinica. presenta.ion,dia.nosis,a.d ***,a.so known a. Berger's disea.e,is the most frequent type of prima.y glomerulonephritis(GN)*** is mostly found a.ong the a.ia. *** presenta.ion ca. be va.ia.le,from microscopic hema.uria.to a.ra.idly progressive *** 50%of pa.ients present with single or recurring episodes of gross *** upper respira.ory infection a.d tonsillitis often precede these *** 30%of pa.ients present microscopic hema.uria.with or without proteinuria.usua.ly detected on routine *** dia.nosis relies on ha.ing a.rena. biopsy for pa.hology a.d immunofluorescence *** focus on risk stra.ifica.ion a.d ma.a.ement of *** provide a.review of a.l the la.dma.k studies to *** to the 2021 KDIGO(kidney disea.e:Improving Globa. Outcomes)guidelines,pa.ients with non-va.ia.t form Iga. a.e first trea.ed conserva.ively for three to six *** a.proa.h consists of a.equa.e blood pressure control,reduction of proteinuria.with renin-a.giotensin system blocka.e,trea.ment of dyslipidemia.a.d lifestyle modifica.ions(weight loss,exercise,smoking cessa.ion,a.d dieta.y sodium restrictions).Following three to six months of conserva.ive thera.y,pa.ients a.e further cla.sified a. high or low risk for disea.e ***-risk pa.ients ha.e proteinuria.1 g/d ora.t microscopic hema.uria.a.d a.tive infla.ma.ion on kidney *** experts consider proteinuria.2 g/d to be very high *** with high a.d very high-risk profiles a.e trea.ed with immunosuppressive thera.y.a.proteinuria.level ofa.d sta.le/im-proved rena. function indica.es a.good trea.ment response for pa.ients on immu-nosuppressive thera.y.

关键词： Immunoglobulin a.nephropa.hy Glomerulonephritis Nephritic syndrome a.giotensin-converting enzyme inhibitor a.giotensin receptor blocker Systemic steroids Mycophenola.e mofetil

Ca.pa.is spinosa.L wa.te a.tiva.ed ca.bon a. a. efficient a.sorbent for crysta. violet toxic dye remova.: Modeling, optimiza.ion by experimenta. design, a.d ecologica. a.a.ysis

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Chinese Journa. of Chemica. Engineering 2024年第7期71卷 283-302页

作者： Moha.med Benjelloun Youssef Miya. Sa.ma.Ssouni Soula.ma. Ia.ch Moha.ed el-ha.a.ha.Sa.ek La.da.i Kha.ija.Sa.a.el Musta.a.Ibousta.en a.dela.iz a.t a.di Sa.a. La.rini Ra.ia.Bousla.ti La.ora.ory of Ma.eria.s ProcessesCatalysisand EnvironmentHigher School of TechnologySidi Mohamed Ben Abdellah UniversityFez 30070Morocco Ministry of Hea.th a.d Socia. Protection Higher Institute of Nursing Professions and Health TechniquesFez/Meknes 30070Morocco La.ora.ory of Biochemistry Faculty of MedicinePharmacy and DentistrySidi Mohamed Ben Abdellah UniversityFez 30070Morocco La.ora.ory of a.plied Chemistry a.d Environment Faculty of SciencesIbnou Zohr UniversityAgadir 80322Morocco Resea.ch Tea. of Energy a.d Susta.na.le Development Higher School of TechnologyIbnou Zohr UniversityGuelmim 81000Morocco Orga.ic Chemistry a.d Physica. Chemistry La.ora.ory Faculty of SciencesIbnou Zohr UniversityAgadir 80322Morocco

Textile dyes a.e dra.a.ic sources of pollution a.d non-a.sthetic disturba.ce of a.ua.ic life a.d therefore represent a.potentia. risk of bioa.cumula.ion tha. ca. a.fect living *** is impera.ive to reduce or elimina.e these dyes from liquid effluents with innova.ive bioma.eria.s a.d ***,this resea.ch a.ms to highlight the performa.ce of Ca.pa.is spinosa.L wa.te-a.tiva.ed ca.bon(CSLW-a.)a.sorbent to remove crysta. violet(CV)from a. a.ueous *** mecha.ism of CV a.sorption on CSLW-a. wa. eva.ua.ed ba.ed on the coupling of experimenta. da.a.a.d different cha.a.teriza.ion *** efficiency of the CSLW-a. ma.eria. reflected by the equilibrium a.sorption ca.a.ity of CV could rea.h more tha. 195.671 mg·g^(–1) when 0.5 g·L^(–1) of CSLW-a.(Pa.ticle size≤250μm)is introduced into the CV of initia. concentra.ion of 100 mg·L^(–1) a. pH 6 a.d tempera.ure 65℃ a.d in the presence of pota.sium ions a.ter 60 min of conta.t time a.cording to the one pa.a.eter a. a.time *** a.sorption beha.ior of CV on CSLW-a. wa. found to be consistent with the pseudo-second-order kinetic model a.d Frumkin's linea. isotherma. *** thermodyna.ic a.pects indica.e tha. the process is physica.,sponta.eous,a.d *** optimiza.ion of the process by the Box Behnken design of experiments resulted in a. a.sorption ca.a.ity a.proa.hing 183.544 mg·g^(–1)([CV]=100 mg·L^(–1) a.d[CSLW-a.]=0.5 g·L^(–1) a. 35 min).The results of the La.tuca.sa.iva.seeds germina.ion in trea.ed CV(70%),a.sorbent solvent a.d therma. regenera.ion(more tha. 5 cycles),a.d process cost a.a.ysis(1.0484 USD·L^(–1))tests a.e encoura.ing a.d promising for future exploita.ions of the CSLW-a. ma.eria. in different industria. fields.

关键词： Box Behnken Ca.pa.is spinosa.L wa.te-a.tiva.ed ca.bon Cost a.a.ysis Isotherm Kinetic Regenera.ion

Ma.hine Lea.ning a.d Da.a.Fusion a.proa.h for ela.tic Rock Properties Estima.ion a.d Fra.tura.ility Eva.ua.ion

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Energy a.d a. 2024年第2期16卷 1-13页

作者： Yiwen Gong Ilha. el-Monier Moha.ed Meha.a The Ohio Sta.e University SimTech LLC Los a.a.os Na.iona. La.ora.ory

a.cura.e rock ela.tic property determina.ion is vita. for effective hydra.lic fra.turing,pa.ticula.ly Young’s modulus due to its link to rock *** study integra.es interdisciplina.y da.a.for better predictions of ela.tic modulus,combining da.a.mining,experiments,a.d ca.ibra.ed *** used the microstructura. insights extra.ted from rock ima.es for geomecha.ica. fa.ies ***,the petrophysica. da.a.a.d well logs were correla.ed with shea. wa.e velocity(Vs)a.d Young’s *** developed a.ma.hine-lea.ning workflow to predict Young’s modulus a.d a.sess rock fra.tura.ility,considering minera. composition,geomecha.ics,a.d *** findings indica.e tha. a.tificia. neura. networks effectively predict Young’s modulus,while K-Mea.s clustering a.d hiera.chica. support vector ma.hines excel in identifying rock a.d geomecha.ica. *** Microsca.e thin section a.a.ysis in conjunction with fra.ture modeling enha.ces our understa.ding of fra.ture geometries a.d fa.ilita.es fra.tura.ility ***,fra.tura.ility is controlled by specific geomecha.ica. fa.ies during initia.ion a.d propa.a.ion a.d influenced by continuity of geomecha.ica. fa.ies in sma.l depth *** conclusion,this study demonstra.es da.a.mining a.d ma.hine lea.ning potentia. for predicting rock properties a.d a.sessing fra.tura.ility,a.ding hydra.lic fra.turing design optimiza.ion through diverse da.a.a.d a.va.ced methods.

关键词： Young’s modulus prediction fra.a.ility eva.ua.ion la.ding point selection rock mecha.ics ma.hine lea.ning

a. introductory review of swa.m technology for spa.ecra.t on-orbit servicing

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Interna.iona. Journa. of Mecha.ica. System Dyna.ics 2024年第1期4卷 3-21页

作者： el Gha.i a.ri Zheng H.Zhu Depa.tment of Mecha.ica. Engineering York UniversityTorontoOntarioCanada

This review pa.er presents a.comprehensive eva.ua.ion a.d forwa.d-looking perspective on the underexplored topic of servicing ta.get objects using spa.ecra.t *** ta.gets ca. be known or unknown,coopera.ive or uncoopera.ive,a.d pose significa.t cha.lenges in modern spa.e opera.ions due to their inherent complexity a.d *** servicing spa.e objects is vita. for a.tive debris remova. a.d broa.er on-orbit servicing ta.ks such a. sa.ellite ma.ntena.ce,repa.r,refueling,orbita. a.sembly,a.d *** effort ha. been invested in the litera.ure to explore the servicing of ta.gets using a.single *** its a.va.ta.es a.d benefits,this pa.er expa.ds the discussion to encompa.s a.swa.m a.proa.h to the *** review covers va.ious single-spa.ecra.t a.proa.hes a.d presents a.critica. exa.ina.ion of the existing,a.though limited,body of work dedica.ed to servicing orbita. objects using multiple *** focus is a.so broa.ened to include some influentia. studies concerning the cha.a.teriza.ion,ca.ture,a.d ma.ipula.ion of physica. objects by genera. multia.ent systems,a.subject with significa.t pa.a.lels to the core interest of this ***,this a.ticle a.so delves into the rea.m of simulta.eous loca.iza.ion a.d ma.ping,highlighting its a.plica.ion within close-proximity opera.ions in spa.e,especia.ly when dea.ing with unknown uncoopera.ive *** a.tention is pa.d to the benefits tha. this field ca. receive from distributed multia.ent ***,a. explora.ion of the promising field of swa.m robotics is presented,with a. empha.is on its potentia. to revolutionize the servicing of orbita. ta.get ***,a.survey of genera. resea.ch directly enga.ing swa.ms in the orbita. context is *** review a.ms to bridge the knowledge ga. a.d stimula.e further resea.ch in the underexplored doma.n of servicing spa.e ta.gets with spa.ecra.t swa.ms.

关键词： spa.e robotics on-orbit servicing close-proximity opera.ions guida.ce a.d na.iga.ion swa.m robotics multia.ent systems object ca.ture a.d ma.ipula.ion simulta.eous loca.iza.ion a.d ma.ping