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Integrative herbal treatments of diabetes in Beni Mellal region of Morocco

Journal of Integrative Medicine 2019年第2期17卷 93-99页

作者： Hanae Naceiri Mrabti Nidal Jaradat Mohamed Reda Kachmar Abdelaziz Ed-Dra Abdelilah Ouahbi Yahia Cherrah Moulay el abbes Faouzi Faculty of Medicine and Pharmacy Pharmacokinetic Team Laboratory of Pharmacology and Toxicology Université Mohammed V-Souissi Department of Pharmacy Faculty of Medicine and Health Sciences An-Najah National University Faculty of Sciences Health and Environment Laboratory Plant Protection Team Moulay Ismail University Faculty of Science Team of Microbiology and Health Laboratory of Chemistry-Biology Applied to the Environment Moulay Ismail University

Objectives: Diabetes is one of the most life-threatening chronic metabolic disorders and is considered a global health problem due to its prevalence and incidence. In Morocco, several herbal preparations are utilized to treat this disease. For this reason, the current study aimed to identify and to collect data about the medicinal plants utilized in folk medicine for the treatment of diabetes in the Beni Mellal region of ***: An ethnobotanical survey was carried out among 400 herbalists, competent villagers and traditional healers from the Beni Mellal region through direct interviews using a semistructured ***: Forty-five medicinal plants belonging to 25 families were identified for their use in diabetes treatment. Interview results showed that the most frequently used plants were Olea europaea, Salvia officinalis, Allium sativum and Trigonella foenum-graecum, with a relative frequency of citation values of24.3%, 23.0%, 22.5% and 20.5%, respectively. Moreover, in this study, the Fabaceae family was the most commonly reported plant family, and the leaves and roots were the most commonly used parts, for the treatment of ***: The Beni Mellal region of Morocco has an important floristic biodiversity of plants used to treat diabetes in traditional medicinal practice. This result provides a good database for pharmacological screenings in the search for plant-based antidiabetic medications.

关键词： Integrative medicine Medicinal plants Diabetes Beni Mellal Morocco Questionnaire

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Antioxidant,antimicrobial,and α-glucosidase inhibitory activities of saponin extracts from walnut(Juglans regia L.) leaves

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Asian Pacific Journal of Tropical Biomedicine 2023年第2期13卷 60-69页

作者： Youssef elouafy Adil el Yadini Salma Mortada Mohamed Hnini Hicham Harhar Asaad Khalid Ashraf NAbdalla Abdelhakim Bouyahya Khang Wen Goh Long Chiau Ming My el abbes Faouzi Mohamed Tabyaoui Laboratory of Materials Nanotechnology and EnvironmentFaculty of SciencesMohammed V University in RabatRabatMorocco Laboratories of Pharmacology and Toxicology Pharmaceutical and Toxicological Analysis Research TeamFaculty of Medicine and PharmacyMohammed V University in RabatRabatMorocco Center of Plant and Microbial Biotechnology Biodiversity and EnvironmentMicrobiology and Molecular Biology TeamFaculty of SciencesMohammed V University in RabatRabatMorocco Substance Abuse and Toxicology Research Center Jazan UniversityJazan 45142Saudi Arabia Medicinal and Aromatic Plants and Traditional Medicine Research Institute National Center for ResearchKhartoumSudan Department of Pharmacology and Toxicology College of PharmacyUmm Al-Qura UniversityMakkahSaudi Arabia Laboratory of Human Pathologies Biology Faculty of SciencesMohammed V University in RabatMorocco Faculty of Data Science and Information Technology INTI International UniversityNilaiMalaysia School of Medical and Life Sciences Sunway UniversitySunway CityMalaysia

Objective:To investigate the relationship between triterpenoid saponin content and antioxidant,antimicrobial,and α-glucosidase inhibitory activities of 70%ethanolic,butanolic,aqueous,supernate and precipitate extracts of Juglans regia ***:Triterpenoid saponins of different Juglans regia leaf extracts were measured by the vanillin *** activity was evaluated against DPPH and ABTS free *** also assessed α-glucosidase inhibitory and antimicrobial activities of the leaf ***’s correlation coefficient was evaluated to determine the correlation between the saponin content and biological ***:The butanolic extract was most effective against DPPH with an IC50of 6.63μg/mL,while the aqueous extract showed the highest scavenging activity against ABTS free radical with an IC50of 42.27μg/***’s correlation analysis indicated a strong negative correlation (r=-0.956) between DPPH radical scavenging activity (IC50) and the saponin content in the samples *** addition,the aqueous extract showed the best α-glucosidase inhibitory activity compared with other *** the extracts had fair antibacterial activity against Bacillus subtilis,Escherichia coli,and Klebsiella pneumoniae except for the aqueous ***:Juglans regia extracts show potent antioxidant,antimicrobial,and α-glucosidase inhibitory *** is a correlation between saponin levels in Juglans regia leaf extracts and the studied ***,additional research is required to establish these relationships by identifying the specific saponin molecules responsible for these activities and elucidating their mechanisms of action.

关键词： Juglans regia leaves Triterpenoid saponin Antioxidant activity DPPH ABTS Antidiabetic activity α-Glucosidase Antimicrobial activity

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Thermo-mechanical vibration analysis of non-local refined trigonometric shear deformable FG beams

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International Journal of Hydromechatronics 2019年第1期2卷 2-2页

作者： Mouffoki Abderrahmane Aicha Bessaim Houari Mohammed Sid Ahmed Abdelhakim Kaci Tounsi Abdelouahed el Abbas adda bedia Laboratoire des Matériaux et Hydrologie Université de Sidi Bel Abbes BP 89 Cité Ben M’hidi Sidi Bel 22000 Algeria Department of Civil Engineering Université Mustapha Stambouli de Mascara Mascara Algeria Département de Génie Civil et de l’hydraulique Université Moulay Tahar de Saida Saida Algeria

In this article, thermo vibration analysis of functionally graded (FG) nanobeams subjected to linear and uniform temperature distribution is studied. The structure is modelled by new efficient shear beam theory considering the effect of shear deformation without shear correction factor. The mentioned theory satisfies the zero boundary traction conditions on the beam surfaces and can be used for transverse shear strains trigonometric distribution. Material properties of the nanostructure are assumed temperature-dependent and FG based on the distribution of power law. The influence of size scale is captured utilising Eringen theory of non-local elasticity.

关键词： Thermo-mechanical vibration refined trigonometric shear deformable FG beams

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An incommensurate fractional discrete macroeconomic system:Bifurcation,chaos,and complexity

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Chinese Physics B 2023年第3期32卷 58-67页

作者： Abderrahmane abbes Adel Ouannas Nabil Shawagfeh Department of Mathematics University of JordanAmman 11942Jordan Department of Mathematics and Computer Science University of Larbi Ben M'hidiOum El Bouaghi 04000Algeria

This study proposes a novel fractional discrete-time macroeconomic system with incommensurate *** dynamical behavior of the proposed macroeconomic model is investigated analytically and *** particular,the zero equilibrium point stability is investigated to demonstrate that the discrete macroeconomic system exhibits chaotic *** using bifurcation diagrams,phase attractors,the maximum Lyapunov exponent and the 0–1 test,we verified that chaos exists in the new model with incommensurate fractional ***,a complexity analysis is carried out utilizing the approximation entropy(ApEn)and C_(0)complexity to prove that chaos ***,the main findings of this study are presented using numerical simulations.

关键词： chaos macroeconomic system discrete fractional calculus complexity

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Complete pathologic response after chemoradiotherapy in a patient with rectal squamous cell carcinoma： a case report

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Cancer Biology & Medicine 2017年第4期14卷 414-417页

作者： Zaied Sonia Daldoul Amira Bhiri Hanene Ammar Nouha Khechine Wiem Toumi Omar abbes Ibtissem Ben Salem Amina Njima Manel Mhabrech Houda Department of Medical Oncology Fattouma Bourguiba University Hospital of Monastir Monastir 5000 Tunisia Department of Surgery Fattouma Bourguiba University Hospital of Monastir Monastir 5000 Tunisia Department of Radiology El Omrane University Hospital of Monastir Monastir 5000 Tunisia Department of Pathological Anatomy Fattouma Bourguiba University Hospital of Monastir Monastir 5000 Tunisia

Squamous cell carcinoma(SCC)of the rectum is a rare disease.A 59-year-old man presented with SCC of the middle rectum located 10 cm from the *** stage of the tumor was revealed to be T3N+*** patient received a combined treatment with cisplatin and fluorouracil in concomitance with external radiation *** then underwent an anterior resection of the *** postoperative histopathological findings classified the tumor as yp T0N0 with cancer-free margins and lymph *** of SCC remains very challenging,and the acquisition of more consistent data is needed.

关键词： Squamous cell carcinoma rectal neoplasm surgery colonoscopy

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Performance Evaluation of Bottom-Standing Submerged Breakwaters in Regular Waves Using the Meshless Singular Boundary Method

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Journal of Ocean University of China 2019年第4期18卷 823-833页

作者： SENOUCI Fawzi CHIOUKH Nadji DRIS Mohammed el-Amine Department of Hydraulics University Djillali Liabes of Sidi Bel-Abbes Sidi Bel-Abbes 22000 Algeria Laboratory of Naval Aero-Hydrodynamics USTO MB Oran 31000 Algeria Laboratory of Civil Engineering and Environment University Djillali Liabes of Sidi Bel-Abbes Sidi Bel-Abbes 22000 Algeria

In this paper, the improved version of the meshless singular boundary method (ISBM) is developed for analyzing the hydrodynamic performance of bottom-standing submerged breakwaters in regular normally incident waves. Both the single and dual prismatic breakwaters of rectangular and trapezoidal forms are examined. Only the impermeable breakwaters are considered in this study. The physical problem is cast in terms of the Laplace equation governing an irrotational flow and incompressible fluid motion with the appropriate mixed-type boundary conditions, and it is solved numerically using the ISBM. The numerical results are presented in terms of the hydrodynamic quantities of reflection and transmission coefficients. The values are first validated against the data of previous studies, computed, and discussed for a variety of structural conditions, including the height, width, and spacing of breakwater submergence. An excellent agreement is observed between the ISBM results and those of other methods. The breakwater width is found to feature marginal effects compared with the height. The present method is shown to accurately predict the resonant conditions at which the maximum reflection and transmission occur. The trapezoidal breakwaters are found to generally present a wide spectrum of reflections, suggesting that they would function better than the rectangular breakwaters. The dual breakwater systems are confirmed to perform much better than single structures.

关键词： meshless improved singular boundary method regular normal waves rectangular and trapezoidal breakwaters reflection transmission

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Nitrogen and Organic Matter Mineralization in the Tunisian Cork Oak Forest: A Laboratory Study

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Open Journal of Forestry 2015年第3期5卷 287-295页

作者： Zouaoui Ikbel abbes Chaabane Ouled Sghaier Wided Hasnaoui Foued Hasnaoui Brahim Smiti Samira Sylvo Pastoral Institute of Tabarka University of Jendouba Jendouba Tunisia Faculty of Sciences of Tunis University of Tunis El Manar Tunis Tunisia

The mineralization of the organic matter is a very important phenomenon which leads to the release of nutriments used by plants. The rate of transformation of the organic matter depends on several factors and parameters such as climatic factors and biological and physicochemical properties of the soil and the litter. In this study, we investigate the effect of the addition of litter of various species as well as the effect of soil moisture on mineralization of organic matter and on mineral nitrogen release in three soils sampled in three cork oak stands during a period of 41 days under the same laboratory conditions. Carbon mineralization was determined using CO2 respiration method, whereas the mineral nitrogen content was measured at the last day of incubation both in soil samples with added plant leaf material, and in control soil samples without addition under two treatments of moisture (40% and 80% WHC—water holding capacity). Our results show that the addition of leaf litter causes an increase in the microbial activity. Soils without addition were significantly different from the plant leaf added soils in respect to carbon mineralization at the end of the incubation period. Moreover, it is noted that the mineralization of carbon is more marked with moisture at 80% than that of 40%, contrary to that of the nitrogen, which is not influenced by the variation of moisture.

关键词： Mineralization Organic Matter Carbon Nitrogen Cork Oak Moisture

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剪力墙和薄壁开口截面作为支撑的高层建筑抗震计算的简化方法

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钢结构 2008年第6期23卷 93-93页

作者： Sid Ahmed Meftah Abdelouahed Tounsi adda bedia el Abbas

对高度方向性能恒定,不对称的建筑结构,提出了近似的抗震分析手算方法。通过剪力墙和薄壁开口截面结构的结合,增加了建筑物的刚度。基于连续技术和达朗伯原理,推导了自由振动的控制方程和相应的特征值问题。应用伽辽金技术,提出了一个... 详细信息

对高度方向性能恒定,不对称的建筑结构,提出了近似的抗震分析手算方法。通过剪力墙和薄壁开口截面结构的结合,增加了建筑物的刚度。基于连续技术和达朗伯原理,推导了自由振动的控制方程和相应的特征值问题。应用伽辽金技术,提出了一个通用的方法对剪力墙和薄壁开口截面结构的耦合振动进行自由振动分析。给出了地震荷载下计算建筑结构循环频率和内力的简化公式。实例验证了方法的适用性和精确性,所提出的方法与有限元计算进行了比较。

关键词：高层建筑特征频率连续法薄壁结构耦合振动内力

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In vitro assessment of antioxidant,neuroprotective,anti-urease and anti-tyrosinase capacities of Tamarix africana leaves extracts

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Journal of Traditional Chinese Medicine 2023年第2期43卷 252-264页

作者： Esma Anissa Trad Khodja Abd el Hamid Khabtane Rabah Arhab Djamila Benouchenne Mohamed Sabri Bensaad Chawki Bensouici Ramazan Erenler Biotechnology WaterEnvironment and Health LaboratoryFaculty of Natural and Life SciencesUniversity Abbes LaghrourKhenchela 40000Algeria Laboratory of Natural Substances Biomolecules and Biotechnological ApplicationsFaculty of Natural and Life SciencesUniversity Larbi Ben M HidiOum El-Bouaghi 04000Algeria Genetics Biochemistry and Plant Biotechnology LaboratoryFaculty of Natural and Life SciencesUniversity Constantine 1Constantine 25000Algeria Pharmaceutical Sciences Research Center Constantine 25000Algeria Laboratory of Cellular and Molecular Physio-Toxicology-Pathology and Biomolecules(LPTPCMB) Faculty of Natural and Life SciencesUniversity Batna 2Batna 05000Algeria Laboratory of Biotechnology of Bioactive Molecules and Cellular Physiopathology(LBMBPC) Faculty of Natural and Life Sciences University Batna 2Batna 05000Algeria Biotechnology Research Center Ali Mendjli UV 03 Constantine 25000Algeria Department of Chemistry Faculty of Science and LiteratureUniversity TokatGaziosmanpasaTokat 60250Turkey

OBJECTIVE:To characterize the chemical profile of methanolic crude extract and its fractions(Ethyl acetate,n-butanol and aqueous)using liquid chromatographymass spectrometry(LC-MS)analysis,to evaluate their biological and pharmacological properties:antioxidant(1,1-diphenyl-2-pycrylhydrazyl(DPPH),2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic)(ABTS·+),galvinoxyle free radical scavenging,reducing power,phenanthroline andβcarotene-linoleic acid bleaching assays),enzymes inhibitory ability against several enzymes[acetylcholinesterase(AChE),buthyrylcholinesterase(BChE),urease and tyrosinase].METHODS:Secondary metabolites were extracted from Tamarix africana air-dried powdered leaves by maceration,the crude extract was fractionated using different solvents with different polarities(Ethyl acetate,n-butanol and aqueous).The amount of polyphenols,flavonoids and tannins(hydrolysable and condensed)were determined using colorimetric assays.A variety of in vitro biochemical tests were carried out to assess antioxidant and oxygen radical scavenging properties using DPPH,ABTS,galvinoxyle free radical scavenging,reducing power,phenanthroline andβcarotene-linoleic acid bleaching *** effect was examined against acetylcholinesterase and buthyrylcholinesterase *** anti-urease and antityrosinase activities were performed against urease and tyrosinase enzymes *** extract’s components were identified using LC-MS and compared to reference ***:The results indicated that Tamarix africana extracts presented a powerful antioxidant activity in all assays and exhibited a potent inhibitory effect against AChE and BChE as well as urease and tyrosinase ***-MS analysis identified amount of eight phenolic compounds were revealed in this analysis;Apigenin,Diosmin,Quercetin,Quercetine-3-glycoside,Apigenin 7-O glycoside,Rutin,Neohesperidin and Wogonin in methanolic extract and its different fractions of Tamarix africana from ***

关键词： antioxidants anti-tyrosinase anti-urease liquid chromatography-mass spectrometry neuroprotection phenolic content Tamarix africana

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GIS, Forest Fire Prevention and Risk Matrix in the National Forest of Khoudida, Sidi Bel abbes, Algeria

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Open Journal of Ecology 2020年第6期10卷 356-369页

作者： Mayssara el Bouhissi Salah Eddine Bachir Bouidjra Khé loufi Benabdeli Laboratoire Ecodé veloppement des espaces Universit&#233 Djillali Liabes de Sidi Bel abbes Sidi Bel Abbes Algeria Laboratoire Gé o-Environnement Universit&#233 Stambouli de Mascara Mascara Algeria

Forest fires in Algeria are ravaging an average of more than 32,000 hectares annually despite the prevention and control plan put in place. They are the most damaging factor of degradation of the forest and weigh heavily on the environment and the local economy. Conventional methods for fire prevention and control are time consuming and are not always reliable in view of the complexity and diversity of forest ecosystems. The main idea behind this study is to use the GIS and remote sensing for the development of a fire risk map of the Khoudida State Forest (Algeria). The approach adopted involves three parameters that control the fire behavior, which are: the top-morphology of the field, the combustibility of the plant cover and hazards. For each factor its correlation with risk was evaluated;the combination of the slope, altitude and exposure parameters in the topo-morphological index and the hazard map made it possible to evaluate the average risk for an area of more than 2132 hectares, 1521 hectares high and only 493 hectares, respectively 51.4%, 36.7% and 11.9%.

关键词： Fire GIS Remote Sensing Vulnerability Forest Hazard Khoudida Risk

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