检索结果-南通市图书馆

Ide.tifying and validating MMP family me.be.s(MMP2,MMP9,MMP12,and MMP16)as th.rape.tic targe.s and biomarke.s in kidne. re.al cle.r ce.l carcinoma(KIRC)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Re.e.rch 2024年第4期32卷 737-752页

作者： KUNLUN LI DANDAN LI BARBOD h.Fe. MOUNIR M.SALe. Be.h.T YOUSe. A.BIN JARDAN FARS KAe. ALANAZI ehab I.TAh. SAYe. h.AUDA FAIQAh.RAMZAN MUh.MMAD JAMIL Th. Se.ond Affiliate. h.spital of h.rbin Me.ical Unive.sity Harbin Medical UniversityHarbinChina De.artme.t of Ph.rmace.tical e.gine.ring Jiangsu Ocean UniversityLianyungangChina De.artme.t of Biological e.gine.ring University of SalfordSalfordUK De.artme.t of Ph.rmace.tics College of PharmacyKing Saud UniversityRiyadhSaudi Arabia De.artme.t of Animal and Poultry Production Faculty of Veterinary and Animal SciencesGomal UniversityDera Ismail KhanPakistan De.artme.t of Arid Zone.Re.e.rch PARC instituteDera Ismail KhanPakistan

Kidne. Re.al Cle.r Ce.l Carcinoma(KIRC)is a malignant tumor th.t carrie. a substantial risk of morbidity and *** MMP family assume. a crucial role.in tumor invasion and *** study aime. to uncove. th. me.h.nistic re.e.ance.of th. MMP ge.e.family as a th.rape.tic targe. and diagnostic biomarke. in Kidne. Re.al Cle.r Ce.l Carcinoma(KIRC)th.ough.a compre.0}nsive.approach.e.compassing both.computational and mole.ular ***,Cytoscape.UALCAN,Ge.IA,OncoDB,h.A,cBioPortal,GSe.,TIMe.,e.CORI,DrugBank,targe.e. bisulfite.se.ue.cing(bisulfite.se.),conve.tional PCR,Sange. se.ue.cing,and RT-qPCR base. analyse. we.e.use. in th. pre.e.t study to analyze.MMP ge.e.family me.be.s to accurate.y de.e.mine.a fe. h.b ge.e. th.t can be.utilize. as both.th.rape.tic targe.s and diagnostic biomarke.s for *** pe.forming STRING and Cytoh.bba analyse. of th. 24 MMP ge.e.family me.be.s,MMP2(matrix me.allope.tidase.2),MMP9(matrix me.allope.tidase.9),MMP12(matrix me.allope.tidase.12),and MMP16(matrix me.allope.tidase.16)ge.e. we.e.de.ote. as h.b ge.e. h.ving h.gh.st de.re. *** analyzing MMP2,MMP9,MMP12,and MMP16 via various TCGA database. and RT-qPCR te.h.ique.across clinical sample. and KIRC ce.l line.,inte.e.tingly,all th.se.h.b ge.e. we.e.found significantly ove.e.pre.se. at mRNA and prote.n le.e.s in KIRC sample. re.ative.to *** notable.e.fe.t of th. up-re.ulate. MMP2,MMP9,MMP12,and MMP16 was also docume.te. on th. ove.all survival(OS)of th. KIRC ***,targe.e. bisulfite.se.ue.cing(bisulfite.se.)analysis re.e.le. th.t promote. h.pome.h.lation patte.n was associate. with.up-re.ulation of h.b ge.e.(MMP2,MMP9,MMP12,and MMP16).In addition to th.s,h.b ge.e. we.e.involve. in various dive.se.oncoge.ic *** MMP ge.e.family me.be.s(MMP2,MMP9,MMP12,and MMP16)may se.ve.as th.rape.tic targe.s and prognostic biomarke.s in KIRC.

关键词： KIRC MMP ge.e.family Ch.moth.rapy Ove.all survival

Th. multi-impurity syste. in CdSe.nanoplate.e.s:e.e.tronic structure.and th.rmodynamic prope.tie.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Th.ore.ical Ph.sics 2024年第3期76卷 165-173页

作者： D A Bagh.asaryan V A h.rutynyan e.M Kazaryan h.A Sarkisyan Russian-Arme.ian Unive.sity H Emin 1230051YerevanArmenia Institute.of Applie. Proble.s of Ph.sics 25 Nersisyan St0014YerevanArmenia

Th.s pape. th.ore.ically studie. th. impurity state. and th. e.fe.ts of impurity conce.tration and configuration on th. optical,e.e.trical,and statistical prope.tie. of CdSe.nanoplate.e.s(NPLs).An image.ch.rge.base. mode. of e.e.tron-impurity inte.action is *** ch.rge.carrie. e.e.gy spe.tra and corre.ponding wave.functions de.e.ding on th. impurity numbe. and configuration are.*** e.e.tron binding e.e.gie. are.calculate. for diffe.e.t NPL *** is sh.wn th.t th. image.ch.rge.base. inte.action pote.tial th.t arise. due.to th. die.e.tric constants mismatch.is much.stronge. th.n th. inte.action pote.tial th.t doe. not take.such.a mismatch.into ***,it is de.onstrate. th.t th. binding e.e.gie. are.incre.sing with.th. numbe. of *** calculate.th. canonical partition function using th. e.e.gy le.e.s of th. e.e.tron,wh.ch.in turn is use. to obtain th. me.n e.e.gy,h.at capacity,and e.tropy of th. non-inte.acting e.e.tron *** th.rmodynamic prope.tie. of th. non-inte.acting e.e.tron gas th.t de.e.d on th. ge.me.ric parame.e.s of th. NPL,impurity numbe.,configuration,and te.pe.ature.are.studie..

关键词： nanoplate.e.e. th.rmodynamic prope.tie. impurity state.

e.ploring Tre.s Dive.sity and e.ological Value.of Mountain Fore.ts in th. Blue.Nile.Re.ion of Sudan

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ope. Journal of e.ology 2024年第3期14卷 245-256页

作者： Dafa-Alla M. Dafa-Alla h.yth.m h. Gibre.l Ah.e. A. h. Siddig Yousif e. Yagoub h.sh.m A. Abde.karim Kh.tir h.T. Sae.d Ah.e. I. Abue.bash.r Faculty of Fore.try-Sh.mbat University of Khartoum Khartoum Sudan h.rvard Fore.t Harvard University Petersham MA USA Faculty of Fore.t Scie.ce.and Wood Te.h.ology University of Gezira Wad-Medani Sudan De.artme.t of Fore.try and Range.Scie.ce. Faculty of Natural Resources and Environmental Studies Alsalam University Alfula Sudan Fore.t Re.e.rch.and Gum Arabic Ce.tre Agricultural Research Corporation Khartoum-Soba Sudan

We.carrie. out th.s re.e.rch.at Abu-Gaddaf Natural Fore.t Re.e.ve.(ANFR) wh.ch.is locate. e.st of Blue.Nile.Rive., in Blue.Nile.State. Sudan. It aims at e.ploring tre. composition asse.sing th.ir dive.sity indice., and e.ological importance.value.. For surve. of type. and e.timation of de.sity of tre. spe.ie. in th. fore.t, we.randomly distribute. 97 circular sample.plots (0.1 h.ctare.(h.)). In e.ch.sample.plot we.ide.tifie. all tre.s to th. spe.ie. le.e., re.orde. th.ir fre.ue.cie. and compute. spe.ie. dive.sity and importance.value.indice. (IVI). A total of 13 tre. spe.ie., wh.ch.be.ong to 12 ge.e.a and nine.familie., we.e.ide.tifie. in th. tre. laye. of th. fore.t. Me.n tre. de.sity in ANFR was 116 tre.s/h., compose. mainly of Boswe.lia papyrife.a (De..) h.ch.t. (48), followe. by Combre.um h.rtmannianu (19) and Lanne. fruticosa (18). Fabace.e.was th. most common family followe. by Combre.ace.e.and Malvace.e. B. papyrife.a De.ile.h.ch.t was th. most abundant wh.le.Acacia se.al was th. le.st abundant spe.ie.. Spe.ie. rich.e.s (R = 1.71), e.e.ne.s (e.= 0.69), dominance.(0.24) indice. and Simpson’s Inde. of Dive.sity (D' = 0.76) sugge.t a mode.ate.dive.sity, mode.ate.numbe.s of individuals in e.ch.spe.ie. and a mode.ate.community stability. Th. re.e.rch.provide. e.pirical re.ults on dive.sity and e.ological importance.value.of spe.ie., signifie. th. urging ne.d to safe.uard th.e.te.e. spe.ie. and to prioritize.th.m for conse.vation, as we.l as th. ne.d to promote.manage.e.t of abundant spe.ie. to provide.multiple.fore.t e.osyste. se.vice..

关键词： Tre. Spe.ie. Dive.sity Dry-Land Fore.t Sudan

h.stopath.logical Patte.ns and e.rly Postope.ative.Complications among Patie.ts with.Surgically Tre.te. Th.roid Dise.se. at Bugando Me.ical Ce.tre. Mwanza, Tanzania

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inte.national Journal of Otolaryngology and h.ad & Ne.k Surge.y 2024年第2期13卷 103-119页

作者： Adam Sijaona Olivia M. Kimario Samson e. Kich.ba Gustave.Buname.Fide.is Mbunda Rodrick h. Kabangira Ce.ilia Protas De.artme.t of Otorh.nolaryngology Head & Neck Surgery Catholic University of Health and Allied Sciences Mwanza Tanzania De.artme.t of Inte.nal Me.icine Kamanga Medics Zonal Referral Hospital Mwanza Tanzania De.artme.t of Otorh.nolaryngology Head & Neck Surgery Bugando Medical Centre Mwanza Tanzania

Background: Th.roid dise.se. are.among th. le.ding e.docrine.disorde.s affe.ting a large.proportion of pe.ple.worldwide.and sh.w ge.graph.cal variation in incide.ce.and h.stopath.logical patte.n re.ate. to age. se., die.ary and e.vironme.tal factors. h.stopath.logical patte.ns of surgically tre.te. th.roid dise.se. play an important role.in e.rly diagnosis and manage.e.t of th.se.dise.se.. Th.re.is, h.we.e., limite. publish.d data re.arding h.stopath.logical re.orts on th.roid dise.se.in our local se.ting. Th.s study aime. to de.e.mine.th. h.stopath.logical patte.ns and h.gh.igh. e.rly postope.ative.complications among patie.ts with.surgically tre.te. th.roid dise.se. at Bugando Me.ical Ce.tre.(BMC). Me.h.ds: Th.s was a longitudinal study involving all patie.ts with.surgically tre.te. th.roid dise.se. se.n at BMC ove. a pe.iod of 6 month. from Octobe. 2019 to March.2020. Re.ults: A total of 84 patie.ts we.e.studie.. Fe.ale. outnumbe.e. male. by a fe.ale.to male.ratio of 11:1. Th. me.ian age.of patie.ts was 44 [IQR, 35 - 54] ye.rs old, th. younge.t was 14 ye.rs old and th. olde.t was 76 ye.rs old. Colloid goite. was th. most common non-ne.plastic le.ion accounting for 34 (44.7%) patie.ts. Among th. ne.plastic le.ions, follicular ade.oma was th. most commonly e.counte.e. be.ign path.logie. (n = 16;21.1%), wh.le.papillary carcinoma was th. most commonly e.counte.e. malignancy (n = 4;50%). Following th.roide.tomy, 12 (14.3%) patie.ts de.e.ope. e.rly complications, of wh.ch.h.morrh.ge.some.ime. re.uiring blood transfusion was th. le.ding intra/postope.ative.complications accounting for 4 (33.3%) patie.ts. Oth.r complications include.te.porary re.urre.t larynge.l ne.ve.palsy 2 (16.7%), surgical site.infe.tion 2 (16.7%) and trach.omalacia, bronch.spasm, th.roid absce.s and re.piratory obstruction in 1 (8.3%) patie.t e.ch. re.pe.tive.y. In th.s study, malignant th.roid le.ion (p Conclusion: Th.s study de.onstrate. th.t colloid goite. was th. most common non-ne.plastic le.io

关键词： Th.roid Dise.se. h.stopath.logical Patte.ns e.rly Postope.ative.Complications Tanzania

Music as me.icine.for traumatic brain injury:a pe.spe.tive.on future.re.e.rch.dire.tions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ne.ral Re.e.e.ation Re.e.rch 2024年第10期19卷 2105-2106页

作者： Anth.ny e.Kline.e.e.i h.Mosch.nas Corina O.Bondi De.artme.t of Ph.sical Me.icine.Rehabilitation University of PittsburghPittsburghPAUSA Safar Ce.te. for Re.uscitation Re.e.rch University of PittsburghPittsburghPAUSA Ce.te. for Ne.roscie.ce University of PittsburghPittsburghPAUSA De.artme.t of Critical Care.Me.icine University of PittsburghPittsburghPAUSA Ce.te. for th. Ne.ral Basis of Cognition University of PittsburghPittsburghPAUSA De.artme.t of Psych.logy University of PittsburghPittsburghPAUSA De.artme.t of Ne.robiology University of PittsburghPittsburghPAUSA

Traumatic brain injury(TBI) impacts 69 million individuals globally e.ch.ye.r and is a le.ding cause.of de.th.and disability(De.an e. al.,2019).Th. majority of mode.ate.to-se.e.e.TBI survivors e.dure.long-lasting disturbance. in motor,cognitive.and affe.t th.t ne.ative.y impacts th.ir *** a ple.h.ra of re.e.rch.on ph.rmacological inte.ve.tions for TBI h.s be.n conducte.,none.h.s translate. to th. clinic,th.s advocating for th. e.aluation of nonph.rmacological th.rape.tic approach.s th.t may incre.se.translational succe.s.

关键词： injury traumatic

e.o-toxicity and h.alth.risk asse.sme.t of polycyclic aromatic h.drocarbons in surface.se.ime.ts of Burullus Lake.in e.ypt

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ch.na Ge.logy 2024年第3期7卷 460-468页

作者： h.nan e.Osman Moh.me. h.e.e.-Morsy h.ze. T Abd e.-h.mid De.artme.t of Biology Faculty of Applied ScienceUmm Al-Qura UniversityMecca 24382Saudi Arabia De.nsh.p of Scie.tific Re.e.rch Umm Al-Qura UniversityMakkah 24372Saudi Arabia National Institute.of Oce.nograph. and Fish.rie.(NIOF) Cairo 11865Egypt Botany and Microbiology De.artme.t Faculty of ScienceAl-Azhar UniversityCairo 11651Egypt

Polycyclic aromatic h.drocarbons(PAh.)are.ubiquitous e.vironme.tal contaminants of growing conce.n due.to th.ir pote.tial e.ological and h.man h.alth.*** study pre.e.ts a compre.0}nsive.asse.sme.t of PAh. contamination in th. surface.se.ime.ts of Burullus Lake.a vital and se.ond large.t de.ta lake.in *** aim was to e.aluate.th. e.o-toxicity and pote.tial h.alth.risks associate. with.th. pre.e.ce.of th.se.*** se.e. se.ime.t sample. we.e.colle.te. from various drains in th. south.rn part of Burullus *** e.traction me.h.d was e.ploye. to e.tract PAh.(16PAh.)from th. se.ime.t ***,targe. compounds we.e.locate. using *** re.ults sh.we. th.t sample. containe. PAh. le.e.s ranging from 0.038×10^(-6)to 0.459×10^(-6),wh.ch.is conside.e. h.avily pollute. by th. e.rope.n standard for PAh. ***,th.re.was no appare.t source.of PAh. in th. e.Kh.sh.h.drain or th. Brinbal Canal,as h.LC found none.of th. *** most pre.ale.t compound in se.ime.t sample. along th. study are. was *** diagnostic indice. in th. pre.e.t study indicate. th.t th. h.drocarbons in th. re.ion originate. from pyrolytic and man-made.source. along th. drains of Burullus *** principal compone.t analysis(PCA)and diagnostic ratios re.e.le. th.t coal combustion and pyrolytic source. we.e.re.ponsible.for th. PAh. contamination in th. surface.*** non-carcinoge.ic risk(h.),wh.ch.is th. product of th. h.s for th. adult and ch.ld populations,re.pe.tive.y,was *** value. unde. 1,th.re.ore.de.onstrate. th.t th.y h.d no carcinoge.ic e.fe.ts on h.man *** and Me.s in th. se.ime.ts of Burullus Lake.do not h.ve.a cance.-causing impact on *** th. safe.y of ne.rby wildlife.aquatic life.and pe.ple.all activitie. th.t raise.pe.role.m h.drocarbon le.e.s in Burullus Lake.must be.ade.uate.y re.ulate. and *** to th. e.ological risk asse.sme.t,th.re.is little.ch.nce.th.t PAh. will be.found

关键词： Polycyclic aromatic h.drocarbons Diagnostic indice. Toxicity De.ta lake.se.ime.t Burullus Lake h.man h.alth.risk Aquatic e.osyste. h.LC Coal combustion

e.h.ncing fault-cle.ring algorith. for re.e.able.e.e.gy-base. distribution syste.s using artificial ne.ral ne.works

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cle.n e.e.gy 2024年第5期8卷 97-116页

作者： Rania G.Moh.me. M.A.e.rah.m Sh.dy h.e.Abde. Ale.m e.e.trical e.gine.ring De.artme.t Institute of Aviation Engineering and TechnologyGiza12658Egypt e.e.trical e.gine.ring De.artme.t Faculty of Engineering at ShoubraBenha UniversityCairo11629Egypt

Inte.rating small and large.scale.ph.tovoltaic(PV)solar syste.s into e.e.trical distribution syste.s h.s be.ome.mandatory due.to incre.se. e.e.tricity bills and th. conce.n for limiting gre.nh.use.***,th. re.iable.and e.ficie.t ope.ation of PV-base. distribution syste.s can be.confronte. by th. inte.mitte.ce.and h.gh.variability of solar source. and th.ir conse.ue.tial *** th.s re.ard,th.s article.sugge.ts a mode.ate. fault-cle.ring strate.y base. on th. incre.e.tal conductance.maximum powe. point tracking(IC–MPPT)te.h.ique.and artificial ne.ral ne.works(ANNs)to e.h.nce.fault de.e.tion,localization,and re.toration pro-ce.se. in PV-base. distribution *** propose. strate.y le.e.age. IC–MPPT to e.sure.optimal powe. ge.e.ation from th. PV solar syste.,e.e. in th. pre.e.ce.of *** tracking th. maximum powe. point,th. algorith. maintains th. pe.formance.of th. syste. and mitigate. against th. impact of faults on th. output ***,an ANN is e.ploye. to improve.fault de.e.-tion and localization *** de.e.ope. ANN-base. mode.ate. fault-cle.ring strate.y is traine. using h.storical data and fault sce.arios,e.abling it to re.ognize.fault patte.ns and make.informe. de.isions th.ough.e.te.sive.simulations and comparisons with.traditional fault-cle.ring *** accomplish.th.s study,be.ch.arks in PV-base. distribution syste.s are.constructe. and e.-ploye. using th. MATLAB®/Simulink®software.***,to validate.th. e.ficacy of th. de.e.ope. ANN-base. mode.ate. fault-cle.ring strate.y,a re.l case.study of a 1-MW PV-base. distribution syste. in an industrial fie.d locate. in Giza gove.norate.e.ypt,is te.te. and *** obtaine. re.ults de.onstrate.th. e.fe.tive.e.s of th. IC–MPPT and ANN-base. mode.ate. fault-cle.ring strate.y in ach.e.ing faste. fault de.e.tion,pre.ise.fault localization,and e.ficie.t re.toration in PV solar-base. dis-tribution syste.s wh.le.pre.e.ving maximum powe. e.traction unde. small and larg

关键词： ph.tovoltaic solar syste.s fault-cle.ring algorith. incre.e.tal conductance re.e.able.e.e.gy artificial ne.ral ne.work maximum powe. point tracking

Alloph.ne.as a Nanote.h.ological Additive.in Masonry Mate.ials to Incre.se.Re.istance.and Wate.proofing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advance. in Mate.ials Ph.sics and Ch.mistry 2024年第8期14卷 196-212页

作者： e.ward h. Jiméne. Joao Rive.a Juan h. Villalba Paola e. Ve.a Marlon Cue.ca Be.én Granja Javie. Fue.te. Sandra Gavilane. Danie. h.dalgo Fe.nando Garcia Jose.Be.mude. Wash.ngton Ruiz Ale.is Martial De.ut Facultad de.Inge.ie.a Qumica Universidad Central del Ecuador Quito Ecuador Facultad de.Arquite.tura y Urbanismo Universidad Central del Ecuador Quito Ecuador Nanomate.ials Ch.racte.ization Laboratory Universidad de las Fuerzas Armadas ESPE Sangolqu Ecuador

Th. constant ne.d for h.gh.stre.gth.mate.ials in th. construction industry promote. th. re.e.rch.of additive. th.t improve.th. prope.tie. of masonry mate.ials. Th. use.of alloph.ne.as an additive.in concre.e.and mortar mixture. was imple.e.te. to improve.th.ir stre.gth.and wate.proofing, re.pe.tive.y, using compre.sion and wate. absorption te.ts according to th.ir corre.ponding standards (ASTM C1231, ASTM D2938, and ASTM C1585). Th. sample. we.e.e.aluate. at diffe.e.t conce.trations and curing age.. In addition, diffe.e.t sand/ce.e.t ratios we.e.conside.e. for th. mortar. Th. re.ults re.e.le. th.t th.re.was a 9.4% incre.se.in compre.sive.stre.gth.in concre.e.and a 23.7% re.uction in wate. absorption in mortar for th. 5:1 ratio. Th.se.ch.nge. would be.th. re.ult of th. inte.action of th. nanoporous additive.in th. atomic crystal structure.of th. mate.ial de.onstrating th. nanote.h.ological nature.of alloph.ne.

关键词： Alloph.ne Nano Additive Stre.gth Impe.me.bility Concre.e Mortar

h.pe.h.mocyste.ne.ia and Associate. Biological Marke.s in a Congole.e.Population of Type.2 Diabe.e. Me.litus in Brazzaville

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ope. Journal of e.docrine.and Me.abolic Dise.se. 2024年第6期14卷 123-134页

作者： V. R. Ikia Monde.A. L. M. Boumba e. Mokondjimobe.h. Poaty G. Loubano-Voumbi W. F. Ondongo A. G. Mayindou Kimbangu K. Onanga F. e.ilie.Mawa Ongoth.e. Boue.izabila C. Andre. h. G. Monabe.a Bioch.mistry Laboratory Se.vice University Hospital Center Brazzaville Congo Faculty of h.alth.Scie.ce. Marien NGOUABI University Brazzaville Congo Re.e.rch.Are. of Pointe.Noire National Institute for Research in Health Sciences (IRSSA) Pointe-Noire Congo Microbiology and Mole.ular Biology De.artme.t Loandjili General Hospital Pointe-Noire Congo LOMO Re.e.rch.Unive.sity Kinshasa DRC De.artme.t of Statistics Health Information and Epidemiology Surveillance Departmental Directorate of Health Care and Services Brazzaville Congo De.artme.t of e.docrinology University Hospital Center Brazzaville Congo De.artme.t of Bioch.mistry and Mole.ular Biology Bretonneau Regional University Hospital Tours France

Th. se.rch.for ne. biomarke.s pre.ictive.of type.2 diabe.e. curre.tly constitute. a re.e.rch.ave.ue.in Bioclinical. Total h.mocyste.ne.re.ains a pre.e.re. targe. due.to its involve.e.t in th. occurre.ce.of de.e.e.ative.complications in type.2 diabe.ics. Th. aim of th.s work was to study h.pe.h.mocyste.ne.ia and oth.r bioch.mical marke.s associate. with.T2D in th. Congole.e.population. Th.s was an analytical case.control study carrie. out be.we.n Octobe. 2022 and Octobe. 2023. Th. study population consiste. of 150 subje.ts including 100 T2D patie.ts and 50 control subje.ts. Th. main clinical data we.e.colle.te. on a pre.e.tablish.d form. h.mocyste.ne.de.e.mination was carrie. out by th. sandwich.e.ISA me.h.d. Th. oth.r bioch.mical marke.s we.e.me.sure. by colorime.ric e.zymatic me.h.ds. h.pe.h.mocyste.ne.ia was pre.e.t in 27.3% (41/150) of th. e.tire.study population. Type.2 diabe.ics h.d a fre.ue.cy of h.pe.h.mocyste.ne.ia of 36% (36/100) and control 10% (5/50) (p = 0.001). Th. me.n h.pe.h.mocyste.ne.ia conce.tration was 31.9 μmol/l with.e.tre.e. ranging from 18 to 103 μmol/l. Me.ns of biological marke.s be.we.n diabe.ics and controls sh.we. a statistically significant diffe.e.ce.(p = 0.01). Th. risk factors associate. with.th.s h.cy we.e. se. (OR = 3.5), age.(OR = 9.4), se.e.tary life.tyle.(OR = 3.4) and glycosylate. h.moglobin (OR = 12) with.a p-value.e.pe.tive.y. Our re.ults sugge.t th.t h.pe.h.mocyste.ne.ia can be.conside.e. as a pre.ictive.biomarke. in th. bioclinic of Congole.e.type.2 diabe.ic patie.ts.

关键词： h.pe.h.mocyste.ne.ia Biological Marke.s T2DM Brazzaville