检索结果-南通市图书馆

General Psychiatry 2024年第3期37卷 335-344页

作者： Natasha Yixuan Ong Finn Jing Jie teo Jane Zi Ying ee Chun En Yau Julian Thumboo Hiang Khoon Tan Qin Xiang Ng NUS Yong Loo Lin School of Medicine National University of SingaporeSingapore Health Services Research Unit Singapore General HospitalSingapore SingHealth Duke-NUS Medicine Academic Clinical Programme Duke-NUS Medical SchoolSingapore Singhealth Duke-NUS Global Health Institute Singapore Duke Global Health Institute Duke UniversityDurhamNorth CarolinaUSA Division of Surgery and Surgical Oncology Singapore General HospitalSingapore Saw Swee Hock School of Public Health National University of Singapore and National University Health SystemSingapore

Background Growing evidence attests to the efficacy of mindfulness-based interventions(MBIs),but their effectiveness for healthcare workers remains *** To evaluate the evidence for MBIs in improving healthcare workers’psychological *** A systematic literature search was conducted on Medline,Embase,Cumulative Index for Nursing and Allied Health Literature,PsycINFO and Cochrane Central Register of Controlled Trials up to 31 August 2022 using the keywords‘healthcare worker’,‘doctor’,‘nurse’,‘allied health’,‘mindfulness’,‘wellness’,‘workshop’and‘program’.Randomised controlled trials with a defined MBI focusing on healthcare workers and quantitative outcome measures related to subjective or psychological well-being were eligible for inclusion.R V.4.0.3 was used for data analysis,with the standardised mean difference as the primary outcome,employing DerSimonian and Laird’s random effects *** of Recommendations,Assessment,Development and Evaluation framework was used to evaluate the quality of ***’s Risk of Bias 2 tool was used to assess the risk of bias in the included *** A total of 27 studies with 2506 participants were included,mostly from the USA,involving various healthcare *** such as stress reduction programmes,apps,meditation and training showed small to large effects on anxiety,burnout,stress,depression,psychological distress and job strain outcomes of the *** effects were also seen in self-compassion,empathy,mindfulness and ***,long-term outcomes(1 month or longer postintervention)varied,and the effects were not consistently *** MBIs offer short-term benefits in reducing stress-related symptoms in healthcare *** review also highlights limitations such as intervention heterogeneity,reduced power in specific subgroup analyses and variable study quality.

关键词： nurse sustained workers

Aggregation-induced emission polymers via reversible-deactivation radical polymerization Special Collection:Distinguished Australian Researchers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Aggregate

Aggregate 2024年第1期5卷 16-46页

作者： Nicholas Kai Shiang teo Bo Fan Aditya Ardana San H.Thang School of Chemistry Monash UniversityClaytonVictoriaAustralia

Aggregation-induced emission(AIE)is a unique phenomenon whereby aggregation of molecules induces fluorescence emission as opposed to the more commonly known aggregation-caused quenching(ACQ).AIE has the potential to be utilized in the large-scale production of AIE-active polymeric materials because of their wide range of practical applications such as stimuli-responsive sensors,biological imaging agents,and drug delivery *** is evident from the increasing number of publications over the years since AIE was first *** addition,the evergrowing interest in this field has led many researchers around the world to develop new and creative methods in the design of monomers,initiators and crosslinkers,with the goal of broadening the scope and utility of AIE *** of the most promising approaches to the design and synthesis of AIE polymers is the use of the reversible-deactivation radical polymerization(RDRP)techniques,which enabled the production of well-controlled AIE materials that are often difficult to achieve by other *** this review,a summary of some recent works that utilize RDRP for AIE polymer design and synthesis is presented,including(i)the design of AIE-related monomers,initiators/crosslinkers;the achievements in preparation of AIE polymers using(ii)reversible addition–fragmentation chain transfer(RAFT)technique;(iii)atom transfer radical polymerization(ATRP)technique;(iv)other techniques such as Cu(0)-RDRP technique and nitroxide-mediated polymerization(NMP)technique;(v)the possible applications of these AIE polymers,and finally(vi)a summary/perspective and the future direction of AIE polymers.

关键词： aggregation-induced emission atom transfer radical polymerization nitroxide-mediated polymerization reversible addition–fragmentation chain transfer reversible-deactivation radical polymerization

Understanding Bonding Nature ofα-Keggin Polyoxometalates[XW_(12)O_(40)]^(n−)(X=Al,Si,P,S):A Generalized Superatomic Perspective

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Energy & Environmental Materials 2024年第6期7卷 176-183页

作者： Rui Li Yulei Shi Famin Yu Rui Wang Haitao Yan Boon K.teo Zhigang Wang Department of Physics Capital Normal UniversityBeijing 100048China Key Laboratory of Material Simulation Methods&Software of Ministry of Education College of PhysicsJilin UniversityChangchun 130012China Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012China State Key Laboratory for Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Institute of Theoretical Chemistry College of ChemistryJilin UniversityChangchun 130012China

α-Keggin polyoxometalates(POMs)[XW_(12)O_(40)]^(n−)(X=Al,Si,P,S)are widely used in batteries owing to their remarkable redox ***,the mechanism underlying the applications appears inconsistent with the widely accepted covalent bonding ***,first-principles calculations show that XW_(12)are core–shell structures composed of a shell and an XO_(4)^(n−)core,both are stabilized by covalent ***,owing to the presence of a substantial number of electrons in W_(12)O_(36)shell,the frontier molecular orbitals of XW_(12)are not only strongly delocalized but also exhibit superatomic properties with high-angular momentum electrons that do not conform to the Jellium *** analysis indicates that energetically high lying filled molecular orbitals(MOs)have reached unusually high-angular momentum characterized by quantum number K or higher,allowing for the accommodation of numerous *** attribute confers strong electron acceptor ability and redox activity to XW_(12).Moreover,electrons added to XW_(12)still occupy the K orbitals and will not cause rearrangement of the MOs,thereby maintaining the stability of these *** findings highlight the structure–activity relationship and provide a direction for tailor-made POMs with specific properties at atomic level.

关键词： first principles molecular orbital polyoxometalate redox activity superatom

Will Sustainable Food Sovereignty Research Be Sustainable in the Future?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences 2024年第1期15卷 165-186页

作者： Teck Choon teo School of Business TMC Institute Tashkent Uzbekistan

The article proposes two agricultural paradigms to address global food production sustainability. First, precision agroecology may unite production-oriented and ecological agriculture, but it offers distinct solutions based on data, innovation, and decision-analysis technologies. The author demonstrates how precision technology and agroecological principles can transform agriculture by 1) minimizing inputs with optimization prescriptions, 2) replacing self-sustaining inputs with location variable rate technology, 3) integrating functional ecosystems into agroecosystems with exact preservation technology, 4) hooking up farmers and consumers via value-based food ecosystems, and 5) establishing equitable agroecology. Hence, precision agroecology provides a rare opportunity to integrate indigenous practices and contemporary technologies to revolutionize farming practices. Precision agroecology can tackle agriculture’s most serious sustainability issues in a world in flux.

关键词： Precision Agriculture Agroecology Biodiversity Food Systems

慢性踝关节不稳患者着地时运动模块的结构和组织策略

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

医用生物力学 2024年第S1期 141-141页

作者：揭天乐徐大涛 teo-ee chon Julien S.Baker 顾耀东宁波大学体育学院匈牙利潘诺尼亚大学工程学院新加坡南洋理工大学化学与生物医学工程学院

目的人类运动涉及一组有限模块的协调激活,这些模块被称为肌肉协同,代表了中枢神经系统的运动控制策略。之前的大多数研究都侧重于孤立的肌肉激活,忽略了运动行为的模块组织。因此,为了加强对慢性踝关节不稳定(CAI)患者多关节运动时肌...

目的人类运动涉及一组有限模块的协调激活,这些模块被称为肌肉协同,代表了中枢神经系统的运动控制策略。之前的大多数研究都侧重于孤立的肌肉激活,忽略了运动行为的模块组织。因此,为了加强对慢性踝关节不稳定(CAI)患者多关节运动时肌肉协调动态的理解,有必要探索其着地时的肌肉协同模式。方法共招募了22名单侧CAI患者和22名健康参与者。采用二阶微分方程递归模型处理表面肌电数据,经过滤波预处理后生成肌肉激活矩阵,将其输入非负矩阵分解模型以提取肌肉协同。利用K-means聚类算法和皮尔逊相关系数对肌肉协同进行分类。统计参数映射(SPM)被用于时间模块参数分析。结果CAI组和健康组中发现了4种肌肉协同模式。在肌肉协同1中,与健康对照组相比,臀大肌在CAI中的肌肉权重显著较高(P=0.003 5)。肌肉协同2显示,健康组的股外侧肌肌肉权重显著较高(P=0.018),相反,在肌肉协同4中,CAI患者的股外侧肌的肌肉重量显著较高(P=0.030)。此外,在肌肉协同2中,CAI患者的胫骨前肌肌肉权重显著更高(P=0.042)。结论CAI患者表现出与健康组相似的模块化组织框架。对协同作用空间模块内振幅调整的分析阐明了胫骨前肌和臀大肌如何适应特定的协同以优化控制策略。不同运动模块中股外侧肌的肌肉权重差异产生了CAI中未探索过生物力学适应性,为康复方案提供了新的视角。

关键词：

Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi Yu Faith teo En Ning Chang Liu Yu-Chi Liu Tissue Engineering and Stem Cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

带有头枕的头颈复合有限元模型在追尾碰撞条件下的运动学分析

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

医用生物力学 2024年第S1期 325-325页

作者：王渊蒋瀚慧 teo-En chon 顾耀东宁波大学体育学院宁波大学大健康研究院

目的本研究建立了详细的三维头颈(C0～C7)和头枕的有限元(FE)模型,其目的是预测头颈的每个颈椎节段在生理性载荷和追尾碰撞条件的冲击下的运动学反应。方法为了验证该模型,在静态屈伸环境下进行了测试,在C0上沿矢状解剖面依次施加1.0...

目的本研究建立了详细的三维头颈(C0～C7)和头枕的有限元(FE)模型,其目的是预测头颈的每个颈椎节段在生理性载荷和追尾碰撞条件的冲击下的运动学反应。方法为了验证该模型,在静态屈伸环境下进行了测试,在C0上沿矢状解剖面依次施加1.0 Nm的力矩,模拟头颈椎屈伸运动。在动态研究中,后端冲击脉冲施加于C7,产生4.5 G和8.5 G的加速度。结果在1.0 N·m生理负荷下,预测的头部运动和位移与之前的研究一致。在追尾碰撞条件下,脉冲加速度峰值和头枕角度对头颈复合体运动学的影响表示,在前200 ms内,各颈椎节段旋转运动的增加/减少率不同。各节段屈曲旋转峰值均低于联合的屈曲ROM,所有节段的伸展峰值随加速度和头枕角度的变化而变化。C7加速度越大,下节段的伸展角峰值越大,但其绝对增量受头枕间距的限制。头枕角度从45°～30°的变化导致C5～C6节段下部的伸展变为屈曲,这进一步证明了头部和头枕之间保持距离的有效性。结论现有的C0～C7有限元模型可以有效地模拟人体颈椎在生理静态和模拟碰撞情况下的总体反应。各节段屈伸的快速变化可能导致相关软组织和骨结构经受超出其材料特性极限的耐受性。说明选择合适的头枕位置和角度可以有效预防车祸中颈椎的损伤。

关键词：

Stricture Free Survival after Urethroplasty: A 6-Year Malaysian Referral Centre Experience

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Urology 2024年第8期14卷 474-485页

作者： Jeffrey Jiajian Lee Ley Khim teo Jieling Cheng Hamid Ghazali Urology Department Hospital Tengku Ampuan Afzan Kementerian Kesihatan Malaysia Putrajaya Malaysia Clinical Research Centre Hospital Pulau Pinang Kementerian Kesihatan Malaysia Putrajaya Malaysia Institute for Clinical Research National Institutes of Health Ministry of Health Malaysia Kuala Lumpur Malaysia

Background: Urethroplasty is the gold standard for treatment for urethral strictures. We describe our results of urethroplasty and analyse the risk factors associated with stricture recurrence and stricture-free survival. Methods: A retrospective review of urethroplasty surgery carried out from 2016-2022. Patient records were analysed to obtain demographics, clinical, pathological and outcome data. Success of surgery is defined as postoperative Qmax > 15 ml/s or absence of any instrumentation of urethra such as urethral dilatation, after removal of urethral indwelling catheter. Results: A total of 66 patients who fulfilled the inclusion criteria were selected. Mean age was 43.8. Mean follow up was 27.2 ± 21.8 months. Stricture recurred in 18 patients (27.3%). Estimated stricture free survival time was 59.6 months (95% CI: 50.87 - 68.37). Previous surgical history for stricture was found to be predictive of stricture recurrence. After adjusting for age, BMI, aetiology of stricture and stricture length, previous surgical history had a risk of stricture recurrence approximately three times higher compared to those without. Conclusion: Previous surgical intervention for urethral stricture was found to be the most significant factor for stricture recurrence. We strongly advocate that the first curative surgery done for urethral strictures should be done in high volume centres and by experienced reconstructive urologists.

关键词： Urethroplasty Urethra Stricture Recurrence Factors Survival Reconstructive Urology

The role of melatonin receptor 1B gene(MTNR1B)in the susceptibility to depression and type 2 diabetes comorbidity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第3期11卷 113-115页

作者： Mutaz Amin Benjamin Rafla Rongling Wu teodor T.Postolache Cclaudia Gragnoli INSERM US14-OrphanetParis 75014France Department of Biochemistry and Molecular Biology Faculty of MedicineAl-Neelain UniversityKhartoum 11121Sudan Division of Endocrinology Department of MedicineCreighton University School of MedicineOmahaNE 68124USA Department of Public Health Sciences Penn State College of MedicineHersheyPA 17033USA Department of Statistics Penn State College of MedicineHersheyPA 17033USA Mood and Anxiety Program Department of PsychiatryUniversity of Maryland School of MedicineBaltimoreMD 21201USA Rocky Mountain Mental llness Research Education and Clinical Center(MIRECC) Veterans Integrated Service Network(VISN)19Military and Veteran Microbiome:Consortium for Research and Education(MVM-CoRE)DenverCO 80246USA Mental Ilness Research Education and Clinical Center(MIRECC) Veterans Integrated Service Network(VISN)5VA Capitol Health Care NetworkBaltimoreMD 21090USA Molecular Biology Laboratory Bios Biotech Multi-Diagnostic Health CenterRome00197Italy

Melatonin is an endogenous monoamine hormone secreted by the pineal *** signaling has been shown to play a role in circadian rhythm regulation,lipid and glucose metabolism,and obesity,and it has anti-inflammatory and antioxidant *** melatonin receptor 1B gene(MTNR1B)is expressed in,among other tissues,the brain and pancreatic beta cells,and risk variants for T2D have been reported as impairing early insulin secretion and increasing fasting glucose levels.^(1) Variants in the MTNR1B gene also have been reported in patients with depression(MDD).

关键词： MTNR1B metabolism properties.