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journal of Animal Science and Biotechnology 2019年第4期10卷 969-980页

作者： Kwangwook Kim Yijie He Xia Xiong Amy Ehrlich Xunde Li Helen Raybould edward R.Atwill Elizabeth A.Maga jens jΦrgensen Yanhong Liu Department of Animal Science University of CaliforniaDavisCA 95616USA School of Veterinary Medicine University of CaliforniaDavisCA 95616USA Chr.Hansen A/S HoersholmDenmark

Background: There is growing evidence to support the beneficial effects of supplementing direct-fed microbials(DFM) on performance, health status, and immune responses of weaned pigs. Therefore, the objective of this study was to investigate dietary supplementation of Bacillus subtilis(DSM 25841) on growth performance, diarrhea, gut permeability and immunity of weaned pigs experimentally infected with a pathogenic F-18 Escherichia coli(E. coli).Results: The F18 E. coli infection reduced(P jejunum compared with non-challenged control. Supplementation of Bacillus subtilis linearly enhanced average daily gain of E. coli infected pigs from d 0 to 5 post-inoculation(PI)(P jejunal mucosa when pigs were fed with the control diet. Supplementation of Bacillus subtilis linearly up-regulated(P jejunal mucosa of E. coli infected pigs. In addition, E. coli infection increased(P < 0.05) the m RNA expression of several immune genes(IL1 A, IL1 B, and IL7 on d 5 PI, and IL1 B, IL6, IL7, and TNF on d 11 PI) in the ileal mucosa of weaned pigs. Inclusion of Bacillus subtilis to control diet linearly down-regulated gene expression of IL1 A on d 5 PI(P = 0.07) and IL6 on d 11 PI(P < 0.05) in ileal mucosa of E. coli infected ***: Supplementation of Bacillus subtilis(DSM 25841) enhanced growth r

关键词： Bacillus subtilis Growth rate Gut barrier function Intestinal inflammation Pathogenic Escherichia coli Weaned pigs

Response of Nitrous Oxide Flux to Addition of Anecic Earthworms to an Agricultural Field

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Open journal of Soil Science 2013年第2期3卷 100-106页

作者： josé A. Amador edward j. Avizinis Laboratory of Soil Ecology and Microbiology 024 Coastal Institute University of Rhode Island Kingston USA.

The burrowing and feeding activities of earthworms may have a strong effect on the flux of N2O from agricultural soils. As such, shifts to agricultural management practices that increase the number of earthworms require an understanding of the role of earthworms in N2O dynamics. We conducted a field experiment to examine the effects of addition of anecic earthworms (Lumbricus terrestris) on N2O flux in a field previously planted with corn (Zea mays) in southern Rhode Island, USA. Plots were amended with (15NH4)2SO4 and either 0 (CTL) or 48 L. terrestris m-2 (EW). The flux of N2O, 15N2O and 15N2 was measured over 28 days between October and November 2008. The EW treatment had a significantly higher flux of N2O and 15N2O 1 - 3 days after 15NH4 addition. No treatment effects were observed on 15N2 flux. The addition of earthworms significantly increased (Day 1) and decreased (Day 12) the mole fraction of N2O relative to the CTL. Our results suggest that anecic earthworm additions can increase N2O flux from inorganic fertilizer N amendments, but the effects appear to short-lived.

关键词： Lumbricus terrestris Anecic Earthworms Fertilizer Nitrogen Nitrous Oxide Flux Denitrification

Sequencing method comparison and crystal structure of luffaculin 1,a novel type 1 ribosome-inactivating protein

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Sequencing method comparison and crystal structure of luffac...

A New Drug Binding Subsite on Human Serum Albumin and Drug-Drug Interaction Studied by X-Ray Crystallography

中国化学会第五届全国结构化学学术会议

作者： edward j.Meehan Laboratory for Structural Biology Department of ChemistryGraduate Programs of BiotechnologyChemistry and Materials ScienceUniversity of Alabama in HuntsvilleHuntsvilleAL 35899USA

＜正＞A novel type 1 ribosome-inactivating protein designated luffaculin 1 was isolated from the seeds of Luffa *** rRNA N-glycosidase activity,luffaculin 1 also demonstrates activities including inhibiting tumor cell...

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A New Drug Binding Subsite on Human Serum Albumin and Drug-D...

Sleep Disordered Breathing Asian ***

中国化学会第五届全国结构化学学术会议

＜正＞3′-azido-3′-deoxythymidine[1]（AZT）is the first clinically effective drug for the treatment of human immunodeficiency virus *** drug interaction with human serum albumin （HSA）[2]has been an important compon...

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华东地区睡眠医学新进展高级研修班

作者： edward j.Morgan Hawaii School of Sleep Medicine and Technology September 2002

＜正＞Evidence-Based Medicine Residents are not correct unless there is evidence Attendings are not correct unless there is evidence Professors are not correct unless there iS evidence

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星萼金丝桃的化学成分和抗氧化活性研究

中国中药杂志 2018年第18期43卷 3701-3707页

作者：纪圆圆 Adam Negrin edward j Kennelly 龙春林中央民族大学生命与环境科学学院北京100081 Lehman College City University of New YorkNew York 10468 中央民族大学民族医药教育部重点实验室北京100081

星萼金丝桃Hypericum stellatum是中国西南地区特有种,也是当地一种重要的民族药用植物。采用UPLC-Q-TOF-MS分析星萼金丝桃的化学成分,初步鉴定了17个化合物,通过DPPH自由基清除法测定抗氧化活性,Folin-Ciocalteu法测定总酚含量,星萼金... 详细信息

星萼金丝桃Hypericum stellatum是中国西南地区特有种,也是当地一种重要的民族药用植物。采用UPLC-Q-TOF-MS分析星萼金丝桃的化学成分,初步鉴定了17个化合物,通过DPPH自由基清除法测定抗氧化活性,Folin-Ciocalteu法测定总酚含量,星萼金丝桃乙酸乙酯萃取层显示出较强的抗氧化活性和较高的总酚含量。选定抗氧化活性强和总酚含量较高的乙酸乙酯层进行化学成分研究,利用正相硅胶、Sephedex LH-20、循环制备高效液相等多种色谱手段对地上部位提取物进行分离纯化,通过一维,二维核磁共振波谱数据对所得化合物进行结构鉴定,在该层萃取物中分离得到10个化合物,分别鉴定为槲皮素(Ⅰ),槲皮素-3-O-β-D-葡萄糖苷(Ⅱ),1,3,6,7-四羟基口山酮(Ⅲ),1,3,5,6-四羟基口山酮(Ⅳ),1,3,7-三羟基口山酮(Ⅴ),3,6,7-三羟基-1-甲氧基口山酮(Ⅵ),calycinoxanthon D(Ⅶ),咖啡酸酸乙酯(Ⅷ),绿原酸(Ⅸ),绿原酸乙酯(Ⅹ)。该研究首次报道我国特有植物星萼金丝桃的化学成分和生物活性,初步明确星萼金丝桃清除自由基、抗氧化活性的物质基础。

关键词：星萼金丝桃 UPLC—Q-TOF—MS 抗氧化活性总酚含量

The Geology of the Everglades and Adjacent Areas Har/DVD

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Acceptability of an adjunct equine-assisted activities and therapies program for veterans with posttraumatic stress disorder and/or traumatic brain injury

2007年

作者： Petuch, edward j. Roberts, Charles

ISBN: (数字)9781420045598

ISBN: (纸本)9781420045581

Painting a complete picture of the history of the Everglades, The Geology of the Everglades and Adjacent Areas brings together theperspectives of various geoscientists to provides an overview of the geology, paleontology, and paleoceanography of the Everglades region. It emphasizes the upper 300 m of the geologic framework of the area and gi

关键词： Geology

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journal of Integrative Medicine 2020年第2期18卷 169-173页

作者： Louisa Sylvia Emerson West Allyson M.Blackburn Carina Gupta Eric Bui Tara Mahoney Geraldine Duncan edward C.Wright Simon Lejeune Thomas j.Spencer Home Base:A Red Sox Foundation and Massachusetts General Hospital Program Massachusetts General HospitalCharlestownMA 02129USA Harvard Medical School BostonMA 02115USA Dauten Family Center for Bipolar Treatment Innovation Massachusetts General HospitalBostonMA 02114USA Equine Immersion ProgramsTM USA Pediatric Psychopharmacology and Adult ADHD Program Massachusetts General HospitalBostonMA 02114USA

Objective: Equine-assisted activities and therapies(EAATs) have been a growing adjunctive integrative health modality, as they allow participants to practice mindfulness, emotional regulation, and self-mastery or self-esteem building skills. Preliminary evidence suggests that these programs may be helpful in reducing posttraumatic stress disorder(PTSD), anxiety, and depressive symptoms. The current study examines the acceptability of integrating an EAAT program as part of a two-week, intensive clinical program for veterans with PTSD and/or traumatic brain injury(TBI).Methods: A family member or support person could accompany veterans and participate in the *** hundred and six participants(veteran n = 62, family n = 44) left the urban environment in an intensive outpatient program(IOP) to attend a two-day, weekend EAAT in rural New Hampshire. Satisfaction surveys were conducted on the last day of the program and examined using thematic ***: The following themes were reported in the surveys: ability of horses to catalyze emotional rehabilitation, effectiveness of immersion in equine-assisted activities, program’s ability to foster interpersonal relationships and necessity of education about PTSD for staff. Participants also reported enjoying the program as highlighted by qualitative feedback, a mean score of 9.76(standard deviation[SD] = 0.61) as reported by veterans and a mean score of 9.91(SD = 0.29) as reported by family members on a 10-point visual analog scale with higher scores indicating a greater overall ***: These data offer preliminary evidence that an adjunct EAAT program is acceptable for veterans with PTSD and/or TBI participating in an IOP.

关键词： Posttraumatic stress disorder Military personnel Traumatic brain injury Complementary and alternative medicine Equine-assisted therapy

Exploiting a metal wire grating in total internal reflection geometry to achieve achromatic polarization conversion

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Photonics Research 2017年第4期5卷 299-304页

作者： XUDONG LIU XUEQUAN CHEN edward P.j.PARROTT EMMA PICKWELL-MACPHERSON Department of Electronic Engineering Chinese University of Hong Kong

We demonstrate how a metal wire grating can work as a 45° polarization converter, a quarter-wave retarder, and a half-wave retarder over a broadband terahertz range when set up in total internal reflection geometry. Classical electromagnetic theory is applied to understand the mechanism, and equations to calculate the polarization state of reflected light are derived. We use a metal grating with a period of 20 μm and width of 10 μm on a fused silica surface: linearly polarized terahertz light incident from fused silica with a supercritical incident angle of 52° is totally reflected by the metal grating and air. The polarization of the terahertz light is rotated by 45°, 90°, and circularly polarized by simply rotating the wire grating. The performance is achromatic over the measured range of 0.1–0.7 THz and comparable to commercial visible light wave retarders.

关键词： THz

Accelerating materials discovery using artificial intelligence, high performance computing and robotics

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npj Computational Materials 2022年第1期8卷 767-775页

作者： edward O.Pyzer-Knapp jed W.Pitera Peter W.j.Staar Seiji Takeda Teodoro Laino Daniel P.Sanders james Sexton john R.Smith Alessandro Curioni IBM Research Europe-Daresbury DaresburyUK IBM Almaden Research Centre San JoseCAUSA IBM Research Europe Zurich RüschlikonSwitzerland IBM Research Tokyo TokyoJapan IBM Thomas j.Watson Research Centre Yorktown HeightsNYUSA

New tools enable new ways of working,and materials science is no *** materials discovery,traditional manual,serial,and human-intensive work is being augmented by automated,parallel,and iterative processes driven by Artificial Intelligence (AI),simulation and experimental *** this perspective,we describe how these new capabilities enable the acceleration and enrichment of each stage of the discovery *** show,using the example of the development of a novel chemically amplified photoresist,how these technologies’ impacts are amplified when they are used in concert with each other as powerful,heterogeneous workflows.

关键词： artificial computing enable