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Soluble CD4 effectively prevents excessive TLR activation of resident macrophages in the onset of sepsis

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Signal Transduction and Targeted Therapy 2023年第7期8卷 3498-3511页

作者： Sheng-yuan zhang Qiu-ping Xu Li-na Shi Shih-wen Li Wei-hong Wang Qing-qing Wang Liao-xun Lu Hui Xiao Jun-hong Wang Feng-ying Li Yin-ming Liang Si-tang Gong Hao-ran Peng zheng zhang Hong Tang CAS Key Laboratory of Molecular Virology and Immunology Institut Pasteur of ShanghaiChinese Academy of SciencesShanghai 210031China The Third People’s Hospital of Shenzhen Shenzhen 518112China University of Chinese Academy of Sciences Beijing 100101China The Laboratory of Genetic Regulators in The Immune System Xin-xiang Medical UniversityXin-xiangHenan Province 453003China The Joint Center of Translational Medicine Guangzhou Women and Children’s Medical Center and Institut Pasteur of ShanghaiGuangzhou 510623China Department of Microbiology Naval Medical UniversityShanghai 200433China State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Centre for Infectious DiseasesCollaborative Innovation Centre for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

T lymphopenia,occurring in the early phase of sepsis in response to systemic inflammation,is commonly associated with morbidity and mortality of septic *** have previously shown that a sufficient number of T cells is required to constrain Toll-like receptors(TLRs)mediated ***,the underlying mechanisms remains ***,we unveil that CD4^(+)T cells engage with MHC II of macrophages to downregulate TLR pro-inflammatory signaling.

关键词： CD4 TLR infections

Ionic liquids produce heteroatom-doped Pt/TiO2 nanocrystals for efficient photocatalytic hydrogen production

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Nano Research 2019年第8期12卷 1967-1972页

作者： Xiuniang Tan Jianling zhang Dongxing Tan Jinbiao Shi Xiuyan Cheng Fanyu zhang Lifei Liu Bingxing zhang zhuizhui Su Buxing Han Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of ColloidInterface and Chemical ThermodynamicsCAS Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China School of Chemical Sciences University of Chinese Academy of SciencesBeijing 100049China Physical Science Laboratory Huairou National Comprehensive Science CenterBeijing 101400China

It is of great importance to develop facile strategies to synthesize catalysts with desirable compositions and structures for high-performance photocatalytic hydrogen generation. In this work, we put forward an ionic liquid assisted one-pot route for the synthesis of heteroatom-doped Pt/TiO2 composite material. This route is simple, environmentally benign and adjustable owing to the designable properties of ionic liquids. The as-synthesized Pt/TiO2 nanocrystals exhibit high activity and stability for the photocatalytic hydrogen generation under simulated solar irradiation. This method can be easily applied to the synthesis of various kinds of metal/TiO2 composites doped with desirable heteroatoms (e.g., F, Cl, Br, etc).

关键词： ionic liquid titanium dioxide platinum heteroatom photocatalyst

Survival of a patient who received extracorporeal membrane oxygenation due to postoperative myocardial infarction: A case report

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World Journal of Clinical Cases 2022年第32期10卷 11861-11868页

作者： Qian-Qian Wang Yi Jiang Jian-Gang zhu Ling-Wei zhang Hong-Jie Tong Peng Shen Department of Intensive Care Unit The First Hospital of JiaxingJiaxing 314001Zhejiang ProvinceChina Department of Osteology The First Hospital of JiaxingJiaxing 314001Zhejiang ProvinceChina Department of Intensive Care Unit Affiliated Jinhua Hospital Zhejiang University School of MedicineJinhua 321000Zhejiang ProvinceChina

BACKGROUND Cardiac arrest after noncardiac surgery is a dangerous complication that may contribute to *** of the high mortality rate and many complications of cardiac arrest,it is very important to identify and correct a reversible etiology *** reporting the treatment process of this case,we aimed to broaden the diagnosis and treatment of cardiac arrest after noncardiac surgery and describe how cardiopulmonary resuscitation using extracorporeal membrane oxygenation(ECMO)can improve a patient’s chance of *** SUMMARY A 69-year-old man visited our hospital complaining of low back pain on July 12,*** resonance imaging showed lumbar disc *** hours after lumbar disc herniation surgery,the patient developed cardiac *** resuscitation was performed,and ECMO was started 60 min after the initiation of cardiopulmonary *** the etiology of early cardiac arrest after surgery,acute myocardial infarction and pulmonary embolism were considered *** on ultrasound evaluation,acute myocardial infarction appeared more *** angiography confirmed occlusion of the left anterior descending branch,and coronary artery stenting was *** artery angiography was performed to exclude pulmonary *** to heparinization during ECMO and coronary angiography,there was a large amount of oozing blood in the surgical ***,heparinfree ECMO was performed in the early stage,and routine heparinized ECMO was performed after hemorrhage ***,the patient was discharged and made a full neurologic *** For early postoperative cardiac arrest,acute myocardial infarction should be considered first,and heparin should be used with caution.

关键词： Noncardiac surgery Extracorporeal membrane oxygenation Cardiopulmonary resuscitation Postoperative myocardial infarction No heparinization Case report©The Author(s)2022.Published by Baishideng Publishing Group Inc.All rights reserved.

Bulk metallic glass rings prepared by a modified water quenching method

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International Journal of Minerals,Metallurgy and Materials 2009年第1期16卷 108-111页

作者： Xing-chao zhang Yong zhang Xiao-hua Chen Guo-liang Chen State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing Beijing 100083 China

Bulk metallic glass rings have the potential applications as annular gasket and active solder in special fields. The bulk metallic glass ring of zГ41.2Ti13.8Cu12.5Ni10.0Be22.5 with the outer diameter, the inner diameter, and the thickness of 38, 36, and 5 mm, respectively, was prepared by using a special shaped quartz tube water quenching method. The mechanical properties along the whole cross section were investigated by a nanoindentation method, and no evident variation of the Young＇s modulus and hardness was found, further indicating the single amorphous structure. Amorphous ring and tube-shape parts with different dimensions can be produced by this method.

关键词： bulk metallic glass machine parts water quenching mechanical properties

“胡焕庸线”两侧高中生健康素养与静坐时长态势特征调查研究

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中国全科医学 2024年第18期27卷 2233-2242页

作者：景涛戴永梅罗健英罗维季烨林凡彭驰张翠军曹彦俊郑清黄玉沈鹤军南京体育学院运动健康学院康复治疗学系江苏省南京市210014 江苏省南京市妇幼保健院南京医科大学附属妇产医院营养科210004 江苏省苏北人民医院扬州大学附属苏北人民医院临床营养科江苏省扬州市225001 北京体育大学运动医学与康复学院北京市100084 江苏省扬州市宝应县妇幼保健院营养科 225800 江苏省扬州市妇幼保健院营养科 225002 上海中医药大学附属上海市中西医结合医院上海市200082 江苏省邗江中学体育教研部江苏省扬州市225009 江苏省溧阳中学体育教研部江苏省溧阳市213300 南京体育学院体育教育与人文学院江苏省南京市210014

背景目前“胡焕庸线”的学术价值已经延伸至其他相关学科,考虑到我国人口众多且分布差异较为明显的特点,本研究借鉴人口地理学的研究成果,旨在探索按照“胡焕庸线”的人口密度分布界定标准,深入研究了“胡焕庸线”两侧城乡高中生的健康... 详细信息

背景目前“胡焕庸线”的学术价值已经延伸至其他相关学科,考虑到我国人口众多且分布差异较为明显的特点,本研究借鉴人口地理学的研究成果,旨在探索按照“胡焕庸线”的人口密度分布界定标准,深入研究了“胡焕庸线”两侧城乡高中生的健康素养和静坐时长的态势特征。目的调查分析“胡焕庸线”两侧东南半壁与西北半壁的城乡高中生健康素养与静坐时长的现状态势特征,为改善我国高中生的身心健康水平提供依据。方法采用分层整群随机抽样方法,于2019年1—3月对我国31个省(直辖市、自治区)在内的62所学校高一、高二学生进行健康素养与静坐时长的调研(统一提前邮寄配发健康素养调查问卷与静坐时间调查问卷各12400份)。采用多元线性回归模型分析方差膨胀系数,校正混杂因素后分析“胡焕庸线”两侧东南半壁与西北半壁高中生静坐时长的影响因素。结果最后纳入健康素养调查问卷9057份,其中东南半壁7489份(82.7%),西北半壁1568份(17.3%);纳入静坐时间调查问卷8031份,其中东南半壁6614份(82.4%),西北半壁1417份(17.6%)。东南半壁高中生健康素养评分、静坐时长均高于西北半壁(z=-4.009、-9.198,P10万元,家庭人口数为1、3、7、9、≥10人的高中生健康素养评分均高于西北半壁(P10万元,家庭人口数为3、4、5、6人的高中生静坐时长均长于西北半壁(P母亲学历(0.131)>父亲学历(-0.056)>健康素养评分(-0.050)。西北半壁高中生静坐时长与健康素养评分(β=0.017)、父亲学历(β=0.789)、母亲学历(β=0.540)均呈正相关(P母亲学历(0.111)>健康素养评分(0.056)。结论东南半壁高中生健康素养评分、静坐时长均高于西北半壁。东南半壁高中生静坐时长与家庭年收入和母亲学历呈正相关,但与健康素养评分和父亲学历呈负相关;西北半壁高中生静坐时长与健康素养评分父母亲学历均呈正相关。家庭年收入对东南半壁高中生静坐时长影响的权重最高,父亲学历对西北半壁高中生静坐时长影响的权重最高。

关键词：胡焕庸线东南半壁西北半壁高中生健康素养静坐时长

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Observations of the step-like accelerating processes of cold ions in the reconnection layer at the dayside magnetopause

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Science Bulletin 2018年第1期63卷 31-37页

作者： Qinghe zhang Michael Lockwood John C.Foster Qiugang zong Malcolm W.Dunlop Shunrong zhang Joran Moen Beichen zhang Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment Institute of Space SciencesShandong UniversityWeihai 264209China Department of Meteorology University of ReadingReading RG6 6BBUK MIT Haystack Observatory WestfordMA 01886USA School of Earth and Space Sciences Peking UniversityBeijing 100087China Space Sciences Division SSTDRutherford Appleton LaboratoryDidcot OX11 OQXUK Department of Physics University of OsloBlindern 0316OsloNorway SOA Key Laboratory for Polar Science Polar Research Institute of ChinaShanghai 200136China

Cold ions of plasmaspheric origin have been observed to abundantly appear in the magnetospheric side of the Earth's magnetopause. These cold ions could affect the magnetic reconnection processes at the magnetopause by changing the Alfvén velocity and the reconnection rate, while they could also be heated in the reconnection layer during the ongoing reconnections. We report in situ observations from a partially crossing of a reconnection layer near the subsolar magnetopause. During this crossing, step-like accelerating processes of the cold ions were clearly observed, suggesting that the inflow cold ions may be separately accelerated by the rotation discontinuity and slow shock inside the reconnection layer.

关键词： Cold ions Magnetic reconnection Ion accelerations Magnetopause

基于InSe/MoTe_(2)异质结构的超灵敏宽光谱光电探测器

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红外与毫米波学报 2024年第3期43卷 314-321页

作者：邢艳辉贺雯馨韩梓硕关宝璐马海鑫马晓辉韩军时文华张宝顺吕伟明曾中明北京工业大学微电子学院光电子技术教育部重点实验室北京100124 长春理工大学高功率半导体激光国家重点实验室吉林长春130022 中国科学院苏州纳米技术与纳米仿生研究所纳米加工平台江苏苏州215123

基于光栅效应的二维材料垂直结构可实现高灵敏度和宽光谱光探测器。本文报告了一种基于硒化铟(InSe)/二碲化钼(MoTe_(2))垂直异质结构的高灵敏度光电探测器,该探测器在365~965 nm波长范围内具有出色的宽光谱探测能力。顶层的InSe用作调... 详细信息

基于光栅效应的二维材料垂直结构可实现高灵敏度和宽光谱光探测器。本文报告了一种基于硒化铟(InSe)/二碲化钼(MoTe_(2))垂直异质结构的高灵敏度光电探测器,该探测器在365~965 nm波长范围内具有出色的宽光谱探测能力。顶层的InSe用作调节沟道电流的光栅层,MoTe_(2)则用作传输层。通过结合两种材料的优势,该光电探测器的响应时间为21.6 ms,比探测率在365 nm光照下可以达到1.05×10^(13)Jones,在965 nm光照下也可达到109 Jones数量级。外量子效率可达1.03×10^(5)%,显示出强大的光电转换能力。

关键词：二维材料宽带光电探测器光栅效应超灵敏

Synthesis and Crystal Structure of the Copper Complex {[Cu(CH_3COO)_2(bbtz)](H_2O)_2}_n

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Chinese Journal of Structural Chemistry 2005年第10期24卷 1129-1132页

作者： zhang Yong zhang Yu-Mei LIU Xun-Gao LI Bao-Long Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry and Chemical Engineering Suzhou University Suzhou 215123 China

The new copper complex { [Cu（CH3COO）2（bbtz）]（H2O）2 }, 1 （bbtz = 1,4-bis（ 1,2,4- triazol-1-ylmethyl）benzene） was synthesized and the structure was determined by single-crystal X-ray diffraction. Crystal data： C16H22CuN6O6, monoclinic, space group P21/n, a = 12.589（5）, b = 6.455（2）, c = 12.677（5） A, β= 98.748（9）°, V= 1018.2（7） A^3, Mr = 457.95, z = 2, Dc= 1.494 g/cm^3, F（000） = 474, μ = 1.118 mm^-1, R = 0.0463 and wR = 0.0939 for 1971 observed reflections with I 〉 2σ（I）. The crystal structure of 1 is a one-dimensional chain via the bridging flexible ligand bbtz.

关键词： crystal structure copper complex triazole ligand synthesis

Indoor channel characteristics based on wideband MIMO measurements at 5.25 GHz

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The Journal of China Universities of Posts and Telecommunications 2008年第4期15卷 46-50页

作者： GAO Xin-ying zhang Jian-hua zhang Ping Key Laboratory of Universal Wireless Communications Ministry of Education Wireless Technology Innovation Institute Beijing University of Posts and Telecommunications Beijing 100876 China

Extensive indoor channel measurements were conducted in Beijing with wideband multiple-input multiple-output （MIMO） sounder at 5.25 GHz. Both line-of-sight （LOS） and non-line-of-sight （NLOS） propagation were measured in the indoor office and hotspot scenarios. On the basis of measured data, statistical channel characteristics are presented in this article, including the empirical path loss （PL） models, three excess delay parameters, circular azimuth spread （CAS）, and circular elevation spread （CES）. Comparative analysis of different propagation mechanisms in two scenarios is conducted. These values are significant for indoor coverage and technical research of MIMO and orthogonal frequency division multiplexing （OFDM） for the international mobile telecommunications-advanced （IMT-Advanced） system.

关键词： channel measurement wideband MIMO path loss excess delay circular azimuth spread circular elevation spread IMT-Advanced