检索结果-南通市图书馆

2019年急性缺血性卒中患者早期管理指南:针对2018年急性缺血性卒中早期管理指南的更新美国心脏协会/美国卒中协会为医疗专业人员制定的指南

在线全文

学校读者我要写书评

暂无评论

国际脑血管病杂志 2020年第1期28卷 1-43页

作者： William J.Powers Alejandro A.Rabinstein Teri Ackerson Opeolu M.Adeoye Nicholas c.Bambakidis Kyra Becker Jose Biller Michael Brown Bart M.Demaerschalk Brian Hoh edward c.jauch chelsea S.Kidwell Thabele M.Leslie-Mazwi Bruce Ovbiagele Phillip A.Scott Kevin N.Sheth Andrew M.Southerl Deborah V.Summers Tirschwell 徐加平(译) 庄圣(译) 郭志良(译) 黄志超(译) 尤寿江(译) 刘慧慧(译) 张霞(译) 石际俊(译) 肖国栋(译) 曹勇军(译) 刘春风(译) 不详苏州大学附属第二医院神经内科卒中中心 215004

背景和目的本指南旨在在单个文件中为治疗急性动脉性缺血性卒中患者的临床医生提供最新的全面系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员以及医院管理人员。本指南将取代2013年版急性缺血性卒中(acute ischemic str... 详细信息

背景和目的本指南旨在在单个文件中为治疗急性动脉性缺血性卒中患者的临床医生提供最新的全面系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员以及医院管理人员。本指南将取代2013年版急性缺血性卒中(acute ischemic stroke,AIS)指南,同时也是对2018年版AIS指南的更新。方法写作组成员由美国心脏协会(American Heart Association,AHA)卒中委员会的科学声明监督委员会任命,代表各领域的医学专家。写作组成员不得对存在企业利益关系的相关议题进行讨论或投票。对2013年版AIS指南的更新最初于2018年1月发表,该版指南已经过AHA科学咨询与协调委员会以及AHA执行委员会批准。2018年4月,在删除部分推荐意见后,该指南的修订版在AHA网站上在线发表。要求写作组审查原始文件并在必要时进行修订。2018年6月,写作组提交了一份经过细微更改并纳入新近发表的重要随机对照试验(受试者数量>100名且具有AIS发病后至少90 d的临床转归)的文件。经过14位专家进行同行评议后,写作组根据同行评议专家的意见进行了适当修改。目前的最终文件已经过写作组全体成员(除非企业利益关系妨碍了成员投票)以及AHA管理机构批准。本指南采用了美国心脏病学学会/AHA 2015年推荐意见分类和证据级别标准以及新版AHA指南格式。结果本指南详细介绍了院前医疗、紧急和急诊评估、静脉和血管内治疗以及院内管理,包括在发病后最初2周内启用的二级预防措施。本指南支持院前和院内卒中医疗系统的一体化概念。结论本指南基于现有证据提供了总体推荐意见,用于指导治疗成年急性动脉性缺血性卒中患者的临床医生。然而,许多情况资料有限,迫切需要对AIS的治疗进行持续研究。

关键词： AHA科学声明重症监护疾病管理急诊医疗服务二级预防卒中治疗

Stroke Patients’ Reintegration into Normal Living Post-Discharge from Inpatient Rehabilitation: An Integrative Review

在线全文

学校读者我要写书评

暂无评论

Open Journal of Therapy and Rehabilitation 2024年第3期12卷 274-300页

作者： Eric F. Tanlaka Omotunmise Agbeyangi Adam Mulcaster edward cruz Faculty of Nursing University of Windsor Windsor ON Canada Leddy Library University of Windsor Windsor ON Canada

Background: Stroke rehabilitation professionals have historically focused rehabilitation on physical functions and overlooked the concept of community reintegration after discharge from inpatient rehabilitation. The lack of focus on psychosocial functions post-stroke may lead to lower levels of satisfaction during community reintegration. Methods: This integrative review synthesized findings from research literature on stroke patients’ reintegration into the community after inpatient rehabilitation to address three research questions: a) What specific physical and psychosocial functions have been identified as predictors of successful reintegration into normal living after stroke?, b) How do physical and psychosocial functions promote successful reintegration into normal living after stroke?, and c) What factors have been identified that hinder stroke patients’ reintegration into normal living after stroke? Results: A systematic search of literature identified sixteen studies that provided significant context for the research questions. What physical and psychosocial functions of stroke patients included, for example, improved mobility, independence in daily activities, reduced disability, psychological well-being, self-efficacy, social support, and personal relationships. How physical and psychosocial functions promote reintegration included, for example, disability management, emotional well-being, self-care independence, sense of purpose, and employment influence. Factors that hinder stroke patients’ reintegration consisted of longer stride time, impaired balance/mobility, activities limitation, severe stroke, presence of comorbidity, depressive symptoms, speech and language challenges, inadequate self-efficacy, fear of falling, older age, low educational level, lack of social support, and social isolation. conclusion: Successful community reintegration after stroke requires a shift of focus from rehabilitation interventions that target physical functions to incl

关键词： Stroke Outpatient Rehabilitation community Reintegration Normal Living Functional Abilities

Diversity and connectedness of brine shrimp viruses in global hypersaline ecosystems

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science china(Life Sciences) 2024年第1期67卷 188-203页

作者： Xuan Dong cixiu Li Yiting Wang Tao Hu Fan Zhang Fanzeng Meng Meirong Gao Xuekai Han Guohao Wang Jiahao Qin Hans Nauwynck edward cHolmes Patrick Sorgeloos Liying Sui Jie Huang Weifeng Shi State Key Laboratory of Mariculture Biobreeding and Sustainable Goods Yellow Sea Fisheries Research InstituteChinese Academy of Fishery SciencesLaboratory for Marine Fisheries Science and Food Production ProcessesLaoshan LaboratoryKey Laboratory of Maricultural Organism Disease ControlMinistry of Agriculture and Rural AffairsQingdao Key Laboratory of Mariculture Epidemiology and BiosecurityQingdao 266071China Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan 250021China Key Laboratory of Emerging Infectious Diseases in Universities of Shandong Shandong First Medical University&Shandong Academy of Medical SciencesTaian 271000China Dalian Ocean University Dalian 116023China Asian Regional Artemia Reference center Tianjin University of Science&TechnologyTianjin 300457China Ghent University Ghent 9000Belgium Sydney Institute for Infectious Diseases School of Medical SciencesThe University of SydneySydney 2006Australia Network of Aquaculture centres in Asia-Pacific Bangkok 10900Thailand School of Public Health Shandong First Medical University&Shandong Academy of Medical SciencesJinan 250117China

Brine shrimp(Artemia)has existed on Earth for 400 million years and has major ecological importance in hypersaline *** a crucial live food in aquaculture,brine shrimp cysts have become one of the most important aquatic products traded ***,our understanding of the biodiversity,prevalence and global connectedness of viruses in brine shrimp is still very limited.A total of 143 batches of brine shrimp(belonging to seven species)cysts were collected from six continents including 21 countries and more than 100 geographic locations worldwide during 1977–*** total,55 novel RNA viruses were identified,which could be assigned to 18 different viral families and related *** viruses were dsRNA viruses,16 were+ssRNA viruses,and 28 were−ssRNA *** analyses of the RNA-directed RNA polymerase(RdRp)showed that brine shrimp viruses were often grouped with viruses isolated from other invertebrates and ***,most brine shrimp viruses were related to those from different hosts that might feed on brine shrimp or share the same ecological niche.A notable case was the novel brine shrimp noda-like virus 3,which shared 79.25%(RdRp)and 63.88%(capsid proteins)amino acid identity with covert mortality nodavirus(cMNV)that may cause losses in *** addition,both virome composition and phylogenetic analyses revealed global connectedness in certain brine shrimp viruses,particularly among Asia and Northern *** highlights the incredible species diversity of viruses in these ancient species and provides essential data for the prevalence of RNA viruses in the global aquaculture *** broadly,these findings provide novel insights into the previously unrecognized RNA virosphere in hypersaline ecosystems worldwide and demonstrate that human activity might have driven the global connectedness of brine shrimp viruses.

关键词： brine shrimp Artemia virus diversity novel virus discovery global connectedness hypersaline ecosystem

cellulosomal hemicellulases:Indispensable players for ensuring effective lignocellulose bioconversion

在线全文

学校读者我要写书评

暂无评论

Green carbon 2024年第1期2卷 57-69页

作者： Min Xiao Ya-Jun Liu edward A.Bayer Akihiko Kosugi Qiu cui Yingang Feng cAS Key Laboratory of Biofuels Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China Shandong Provincial Key Laboratory of Synthetic Biology Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China Shandong Engineering Laboratory of Single cell Oil Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China Shandong Energy Institute Qingdao 266101China Qingdao New Energy Shandong Laboratory Qingdao 266101China University of chinese Academy of Sciences Beijing 100049China Department of Biomolecular Sciences The Weizmann Institute of ScienceRehovot 7610001Israel Department of Life Sciences and the National Institute for Biotechnology in the Negev Ben-Gurion University of the NegevBeer-Sheva 8499000Israel Biological Resources and Post-harvest Division Japan International Research Center for Agricultural Sciences(JIRCAS)1-1 OhwashiTsukubaIbaraki 305-8686Japan

The bioconversion of lignocellulose has attracted global attention,due to the significant potential of agricultural and forestry wastes as renewable zero-carbon resources and the urgent need for substituting fossil *** cellulosome system is a multi-enzyme complex produced by anaerobic bacteria,which comprises cellulases,hemicellulases,and associated enzymatic and non-enzymatic components that promote biomass *** enhance their efficiency in degrading recalcitrant lignocellulosic matrices,cellulosomes have been employed to construct biocatalysts for lignocellulose bioconversion,such as consolidated bioprocessing and consolidated ***,the second most abundant polysaccharides in plant cell walls,hold valuable application potential but can also induce inhibitory effects on cellulose hydrolysis,thus highlighting the indispensable roles of hemicellulases within the cellulosome *** review evaluated current research on cellulosomal hemicellulases,comparing their types,abundance,and regulation,primarily focusing on eight known cellulosome-producing species of different *** also reviewed their growth conditions,their hemicellulose-degrading capabilities,and the inhibitory effects of hemicellulose on cellulosome-based lignocellulose ***,we proposed strategies for targeted enhancement of hemicellulase in cellulosomes to improve lignocellulose bioconversion in future studies.

关键词： cellulosome Lignocellulose Hemicellulase Saccharification Biocatalyst

Six psychotropics for pre-symptomatic ＆ early Alzheimer＇s (McI), Parkinson＇s, and Huntington＇s disease modification

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2016年第11期11卷 1712-1726页

作者： edward c. Lauterbach Psychiatry and Neurology Mercer University School of Medicine Macon GA USA

The quest for neuroprotective drugs to slow the progression of neurodegenerative diseases （NDDs）, including Alzheimer＇s disease （AD）, Parkinson＇s disease （PD）, and Huntington＇s disease （HD）, has been largely unrewarding. Preclinical evidence suggests that repurposing quetiapine, lithium, valproate, fluoxetine, donepezil, and memantine for early and pre-symptomatic disease-modification in NDDs may be promising and can spare regulatory barriers. The literature of these psychotropics in early stage and pre-symptomatic AD, PD, and HD is reviewed and propitious findings follow. Mild cognitive impairment （McI） phase of AD： salutary human randomized controlled trial findings for low-dose lithium and, in selected patients, donepezil await replication. Pre-symptomatic AD： human epidemiological data indicate that lithium reduc- es AD risk. Animal model studies （AMS） reveal encouraging results for quetiapine, lithium, donepezil, and memantine. Early PD： valproate AMS findings show promise. Pre-symptomatic PD： lithium and valproate AMS findings are encouraging. Early HD： uncontrolled clinical data indicate non-progression with lithium, fluoxetine, donepezil, and memantine. Pre-symptomatic HD： lithium and valproate are auspicious in AMS. Many other promising findings awaiting replication （valproate in McI; lithium, valproate, fluoxetine in pre-symptomatic AD; lithium in early PD; lithium, valproate, fluoxetine in pre-symptomatic PD; donepezil in early HD; lithium, fluoxetine, memantine in pre-symptomatic HD） are reviewed. Dose- and stage-dependent effects are considered. Suggestions for signal-enhancement in human trials are provided for each NDD stage.

关键词： drug repositioning neuroprotective agents psychotropic drugs neurodegenerative diseases mildcognitive impairment humans animals animal models

Advancements in prokaryotic systematics and the role of Bergey's International Society for Microbial Systematics in addressing challenges in the meta-data era

在线全文

学校读者我要写书评

暂无评论

National Science Review 2024年第7期11卷 292-304页

作者： Jian-Yu Jiao Rashidin Abdugheni Dao-Feng Zhang Iftikhar Ahmed Mukhtiar Ali Maria chuvochina Svetlana N.Dedysh Xiuzhu Dong Markus G?ker Brian P.Hedlund Philip Hugenholtz Kamlesh Jangid Shuang-Jiang Liu edward R.B.Moore Manik Prabhu Narsing Rao Aharon Oren Ramon Rossello-Mora Bhagwan Narayan Rekadwad Nimaichand Salam Wensheng Shu Iain c.Sutcliffe Wee Fei Aaron Teo Martha E.Trujillo Stephanus N.Venter William B.Whitman Guoping Zhao Wen-Jun Li State Key Laboratory of Biocontrol Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) School of Life Sciences Sun Yat-Sen University State Key Laboratory of Desert and Oasis Ecology Key Laboratory of Ecological Safety and Sustainable Development in Arid LandsXinjiang Institute of Ecology and Geography Chinese Academy of Sciences Jiangsu Province Engineering Research center for Marine Bio-resources Sustainable Utilization&college of Oceanography Hohai University National culture collection of Pakistan(NccP) Land Resources Research Institute(LRRI) National Agricultural Research Centre(NARC) The University of Queensland School of Chemistry and Molecular Biosciences Australian Centre for Ecogenomics Winogradsky Institute of Microbiology Research Center of BiotechnologyRussian Academy of Sciences State Key Laboratory of Microbial Resources Institute of Microbiology Chinese Academy of Sciences Leibniz Institute DSMZ–German collection of Microorganisms and cell cultures School of Life Sciences University of Nevada Nevada Institute of Personalized Medicine University of Nevada Bioenergy Group MACS Collection of Microorganisms Agharkar Research Institute State Key Laboratory of Microbial Technology Shandong University Department of Infectious Disease Institute for Biomedicine and Culture Collection University of Gothenburg(CCUG) Institute for BiomedicineSahlgrenska AcademyUniversity of Gothenburg Instituto de ciencias Aplicadas Facultad de Ingeniería Universidad Autónoma de Chile The Alexander Silberman Institute of Life Sciences The Edmond J.Safra Campus The Hebrew University of Jerusalem Marine Microbiology Group Department of Animal and Microbial Biodiversity Mediterranean Institute for Advanced Studies(IMEDEA CSIC-UIB) MicrobeAI Lab Division of Microbiology and Biotechnology Yenepoya Research Centre Yenepoya(Deemed to be University) National Agri-Food Biotechnology Institute Institute of Ecological Science Sch

Prokaryotes are ubiquitous in the biosphere, important for human health and drive diverse biological and environmental processes. Systematics of prokaryotes, whose origins can be traced to the discovery of microorganisms in the 17th century, has transitioned from a phenotype-based classification to a more comprehensive polyphasic taxonomy and eventually to the current genome-based taxonomic *** transition aligns with a foundational shift from studies focused on phenotypic traits that have limited comparative value to those using genome sequences. In this context, Bergey's Manual of Systematics of Archaea and Bacteria(BMSAB) and Bergey's International Society for Microbial Systematics(BISMiS) play a pivotal role in guiding prokaryotic systematics. This review focuses on the historical development of prokaryotic systematics with a focus on the roles of BMSAB and BISMiS. We also explore significant contributions and achievements by microbiologists, highlight the latest progress in the field and anticipate challenges and opportunities within prokaryotic systematics. Additionally, we outline five focal points of BISMiS that are aimed at addressing these challenges. In conclusion, our collaborative effort seeks to enhance ongoing advancements in prokaryotic systematics, ensuring its continued relevance and innovative characters in the contemporary landscape of genomics and bioinformatics.

关键词： prokaryotic systematics Bergey's Manual of Systematics of Archaea and Bacteria (BMSAB) Bergey's International Society for Microbial Systematics (BISMiS) meta-data era

Redefining pandemic preparedness:Multidisciplinary insights from the cERP modelling workshop in infectious diseases,workshop report

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Infectious Disease Modelling 2024年第2期9卷 501-518页

作者： Marta c.Nunes edward Thommes Holger Fröhlich Antoine Flahault Julien Arino Marc Baguelin Matthew Biggerstaff Gaston Bizel-Bizellot Rebecca Borchering Giacomo cacciapaglia Simon cauchemez Alex Barbier--chebbah carsten claussen christine choirat Monica cojocaru catherine commaille-chapus chitin Hon Jude Kong Nicolas Lambert Katharina B.Lauer Thorsten Lehr cédric Mahe Vincent Marechal Adel Mebarki Seyed Moghadas Rene Niehus Lulla Opatowski Francesco Parino Gery Pruvost Andreas Schuppert Rodolphe Thiébaut Andrea Thomas-Bachli cecile Viboud Jianhong Wu Pascal crépey Pascalcrepey center of Excellence in Respiratory Pathogens(cERP) Hospices Civils de Lyon(HCL)and Centre International de Recherche en Infectiologie(CIRI)Équipe SantéPubliqueÉpidémiologie etÉcologieÉvolutive des Maladies Infectieuses(PHE3ID)Inserm U1111CNRS UMR5308ENS de LyonUniversitéClaude Bernard Lyon 1LyonFrance South African Medical Research council Vaccines&Infectious Diseases Analytics Research UnitFaculty of Health SciencesUniversity of the WitwatersrandJohannesburgSouth Africa New Products and Innovation(NPI) Sanofi Vaccines(Global)TorontoOntarioCanada Department of Mathematics and Statistics University of GuelphGuelphOntarioCanada Fraunhofer Institute for Algorithms and Scientific computing(ScAI) Department of BioinformaticsSchloss BirlinghovenSankt AugustinGermany University of Bonn Bonn-Aachen International Center for IT(b-it)BonnGermany Institute of Global Health Faculty of MedicineUniversity of GenevaGenevaSwitzerland and Swiss School of Public HealthZürichSwitzerland Department of Mathematics University of ManitobaWinnipegManitobaCanada MRc centre for Global Infectious Disease Analysis School of Public HealthImperial College LondonLondonUK centre for Mathematical Modelling of Infectious Diseases Department of Infectious Disease EpidemiologyLondon School of Hygiene&Tropical MedicineLondonUK National center for Immunization and Respiratory Diseases(NcIRD) US Centers for Disease Control and Prevention(CDC)AtlantaGAUSA Departement of computational Biology Departement of Global HealthInstitut PasteurParisFrance Institut de Physique des Deux Infinis de Lyon(IP2I) UMR5822IN2P3/CNRSUniversitéClaude Bernard Lyon 1VilleurbanneFrance Mathematical Modelling of Infectious Diseases Unit Institut PasteurUniversitéParis CitéUMR2000 CNRSParisFrance Decision and Bayesian computation Institut PasteurUniversitéParis CitéCNRS UMR 3571France Fraunhofer-Institute for Translational Medicine and Pharmacology HamburgGermany Institute of Global Health Faculty of MedicineUniversity of

In July 2023,the center of Excellence in Respiratory Pathogens organized a two-day workshop on infectious diseases modelling and the lessons learnt from the covid-19 *** report summarizes the rich discussions that occurred during the *** workshop participants discussed multisource data integration and highlighted the benefits of combining traditional surveillance with more novel data sources like mobility data,social media,and wastewater *** advancements were noted in the development of predictive models,with examples from various countries showcasing the use of machine learning and artificial intelligence in detecting and monitoring disease *** role of open collaboration between various stakeholders in modelling was stressed,advocating for the continuation of such partnerships beyond the pandemic.A major gap identified was the absence of a common international framework for data sharing,which is crucial for global pandemic ***,the workshop underscored the need for robust,adaptable modelling frameworks and the integration of different data sources and collaboration across sectors,as key elements in enhancing future pandemic response and preparedness.

关键词： Modelling covid-19 Infectious diseases Pandemic preparedness Workshop

Extraction of 17β-estradiol in water using non-imprinted polymer submicron particles in membrane filters

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2010年第11期22卷 1820-1825页

作者： Yiyan Li edward P. c. Lai Institute of Environmental Science Carleton University 1125 Colonel By Drive Ottawa Ontario K1S 5B6 Canada. Department of chemistry Carleton University 1125 Colonel By Drive Ottawa Ontario K1S 5B6 Canada

17β-Estradiol （E2） is an endocrine disrupting chemical of harm to both animals and human beings at a low concentration level （ng/L）. It cannot be completely removed by wastewater treatments, and is often detected in both environment and drinking waters. The purpose of this feasibility study, towards environmental engineering in the field of water analysis and treatment, was to remove E2 by extraction using non-imprinted polymer （NIP） submicron particles. Experimental results showed that 0.5 mg/L of E2 could be completely extracted by adding 10 mg of NIP particles directly into 10 mL of water. However, the extraction efficiency decreased to 64% for 100 mL of water. prefilling the NIP particles inside a membrane filter showed a potential for water treatment of a large volume, requiring no effort to distribute the particles uniformly in the water. High extraction efficiency （80 ± 10）% for E2 was achieved for 100 mL of water. A total mass of 0.29 mg E2 was extracted from 1000 mL of water containing 0.8 mg/L E2 （by using only 10 mg of NIP particles）. Both efficiency and mass capacity can be increased, by scaling up the amount of NIP particles, towards environmental engineering applications.

关键词： 17β-estradiol non-imprinted polymer submicron particles membrane filter pollution abatement technology

卒中医疗体系之急诊医疗服务的实施策略美国心脏协会/美国卒中协会急诊医疗服务体系专家组和卒中委员会的政策声明

在线全文

学校读者我要写书评

暂无评论

中华脑血管病杂志（电子版） 2008年第6期2卷 354-370页

作者： Joe E.AckerⅢ Arthur M.Pancioli Todd J.crocco Marc K.Eckstein edward c.jauch Hollynn Larrabee Neil M.Meltzer William c.Mergendahl John W.Munn Susanne M.Prentiss charles Sand Jeffrey L.Saver Brian Eigel Brian R.Gilpin Mark Schoeberl Penelope Solis JoAnne R.Bailey Katie B.Horton Steven K.Stranne 曹勇军李瑞霞刘建芳刘春风苏州大学附属第二医院神经内科 215004

尽管卒中的预防、诊断、治疗和康复已取得一些进展，但卒中在美国仍然是第三大死亡原因和长期残疾的主要原因。每年约有70万人新发或复发卒中。在过去10年里，急性卒中诊治的一些进展，包括纤溶和其他短期疗法的引入，

关键词：美国心脏协会急诊医疗服务体系卒中协会医疗体系委员会专家组死亡原因急性卒中