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World Journal of Hepatology 2022年第10期14卷 1899-1906页

作者： Paula K Reine Flavia Feier eduardo antunes da fonseca Rosely G Hernandes Joao Seda-Neto Department of Psychology Hospital Sirio-LibanesSao Paulo 01308901Brazil Department ofLiver Transplantation Santa Casa de Porto AlegrePorto Alegre 90020090Brazil Department of Liver Transplantation Hospital Sirio-LibanesSao Paulo 01308901Brazil

BACKGROUND Living donor liver transplantation is a safe alternative for patients on a liver transplant *** evaluation goes beyond physical variables to include social,emotional,and ethical *** role of pre-donation sociopsychological evaluation of the donor candidate is as important to the success of the procedure as is the medical *** implies recovery from the operation and pro-mpt engagement in pre-transplant professional and social activities,without leading to psychological or physical *** profiling of potential living liver donors(PLLD)and evaluation of quality of life(QOL)can influence *** To evaluate the socio-demographics and psychological aspects(QOL,depression,and anxiety)of PLLD for pediatric liver transplantation in a cohort of 250 *** This was a retrospective cohort study of 250 PLLD who underwent psychological pre-donation evaluation between 2015 and *** the recipients were *** Beck anxiety inventory,Beck depression inventory,and 36-item short-form health survey(SF-36)scores were used to evaluate anxiety(Beck anxiety inventory),depression(Beck depression inventory),and QOL,*** A total of 250 PLLD were *** of them were women(54.4%),and the mean age was 29.2±7.2 years.A total of 120(48.8%)PLLD were employed at the time of evaluation for donation;however,most had low income(57%earneddation for effective and sa

关键词： Liver transplantation Children Outcomes Living donation

Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation

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World Journal of Gastroenterology 2021年第12期27卷 1161-1181页

作者： Karina Gordon Estela Regina Ramos Figueira Joel Avancini Rocha-Filho Luiz Antonio Mondadori eduardo Henrique Giroud Joaquim Joao Seda-Neto eduardo antunes da fonseca Renata Pereira Sustovitch Pugliese Agustin Moscoso Vintimilla Jose Otavio Costa Auler Jr Maria Jose Carvalho Carmona Luiz Augusto Carneiro D'Alburquerque Division of Anesthesiology Hospital das ClínicasUniversity of São Paulo School of MedicineSão Paulo 05403-000Brazil Department of Anesthesiology AC Camargo Cancer CenterSão Paulo 01509-010Brazil Department of Gastroenterology Discipline of Liver and Gastrointestinal TransplantationLaboratory of Medical Investigations LIM37 Hospital das ClinicasUniversity of São Paulo School of MedicineSão Paulo 05402-000Brazil Department of Liver Transplantation AC Camargo Cancer CenterSão Paulo 01525-901Brazil Department of Gastroenterology Division of Liver and Gastrointestinal TransplantHospital das ClinicasUniversity of São Paulo School of MedicineSão Paulo 05402-000Brazil

BACKGROUND The impact of perioperative blood transfusion on short-and long-term outcomes in pediatric living donor liver transplantation(PLDLT)must still be ascertained,mainly among young *** and surgical postoperative complications related to perioperative blood transfusion are well described up to three months after adult liver *** To determine whether transfusion is associated with early and late postoperative complications and mortality in small patients undergoing *** We evaluated the effects of perioperative transfusion on postoperative complications in recipients up to 20 kg of body weight,submitted to PLDLT.A total of 240 patients were retrospectively allocated into two groups according to postoperative complications:Minor complications(n=109)and major complications(n=131).Multiple logistic regression analysis identified the volume of perioperative packed red blood cells(RBC)transfusion as the only independent risk factor for major postoperative *** receiver operating characteristic curve was drawn to identify the optimal volume of the perioperative RBC transfusion related to the presence of major postoperative complications,defining a cutoff point of 27.5 mL/***,patients were reallocated to a low-volume transfusion group(LTr;n=103,RBC≤27.5 mL/kg)and a high-volume transfusion group(HTr;n=137,RBC>27.5 mL/kg)so that the outcome could be *** High-volume transfusion was associated with an increased number of major complications and mortality during hospitalization up to a 10-year follow-up *** a short-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and bleeding complications,with a decrease in rejection complications compared to the *** a long-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and minor neoplastic complications,with a decrease in rejection ***,Cox hazard regr

关键词： Liver transplantation Child Blood transfusion Outcome Liver cirrhosis Mortality

Sharp differentiation on the performance of plant functional groups across natural edges

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Journal of Plant Ecology 2019年第1期12卷 186-198页

作者： Evelyn da fonseca Alecrim Bragion Gabriela Aparecida Oliveira Coelho Flávia Freire de Siqueira Maria Uriarte eduardo van den Berg Department of Forest Engineering Federal University of LavrasCampus UniversitárioCaixa Postal 3037CEP 37200-000LavrasMGBrazil Department of Ecology Evolution and Environmental BiologyColumbia UniversityNew YorkNYUSA

Aims Gallery forests within grasslands have natural edges with open envi-ronments and offer a unique opportunity to examine how species performances vary across environmental ***,we asked if demographic rates of tree functional groups varied along the edge,if we could explain differences in plant strategies and performance through functional traits and which traits increase growth and sur-vival in natural *** We examine mortality and recruitment within the first 10 m of nat-ural edges of eight gallery forests using demographic data from five annual *** defined a priori plant strategies using tree functional groups:light demanding,pioneer and shade *** Findings The shade-tolerant group had the lowest mortality rates and basal area(BA)loss,while pioneer and light-demanding species had similar behavior for these *** survival and growth of functional groups were affected differently by the distance from the *** pioneer group survived more near the edge,while light-demanding and shade-tolerant groups toward the forest *** groups had higher growth in the *** differences could be explained by functional traits since most species have an acquisition strategy:higher specific leaf area and growth,lower leaf dry matter con-tent,lighter stem density,deeper crowns and less slender *** traits enhanced ***,mortality selected both strategies,but in distinct edge’s *** study showed that the high diversity found in natural edges can be explained by a niche and functional perspective,where differences in functional traits lead to differential performance along the environmental gradient.

关键词： edges diversity gradient niche hypothesis SLA LDMC

Ecophysiological acclimatization to cyclic water stress in Eucalyptus

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Journal of Forestry Research 2020年第3期31卷 797-806页

作者： Rogerio de Souza Noia Junior Genilda Canuto Amaral Jose eduardo Macedo Pezzopane Mariana Duarte Silva fonseca Ana Paula Camara da Silva Talita Miranda Teixeira Xavier Department of Biosystems Engineering ESALQ University of Sao PauloPiracicabaSao PauloBrazil Department of Forestry Sciences NEDTEC Federal University of Espirito SantoJero nimo MonteiroEspirito SantoBrazil

Drought is considered the main environmental factor limiting productivity in eucalyptus plantations in Brazil. However, recent studies have reported that exposure to water deficit conditions enables plants to respond to subsequent stresses. Thus, this study investigates the ecophysiological acclimatization of eucalyptus clones submitted to recurrent water deficit cycles. Eucalyptus seedlings were submitted to three recurrent water deficit cycles and anatomical, morphological and physiological changes were analyzed. The results were:(1) Eucalyptus seedlings responded to water deficits by directing carbohydrates to root and stem growth;(2) Size and number of stomata were reduced;(3) Stomatal conductance decreased which allowed the plants to reduce water losses through transpiration,increasing instantaneous water use efficiency;(4) The relationship between gas exchanges and available water contents allowed the seedlings to uptake the retained soil water athigher tensions;and,(5) Physiological recovery from subsequent water deficits became faster. As a result of these changes, the eucalyptus seedlings recovered from the same degree of water stress more rapidly.

关键词： Carbon partition Drought Gas exchange Morpho-physiological changes Photosynthetic apparatus

Mapping of the Use of Waste as Raw Materials for Biogas Production

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Journal of Environmental Protection 2017年第2期8卷 120-130页

作者： Rafaela Lora Grando Fabiana Valeria da fonseca Adelaide Maria de Souza antunes Graduate Program in Chemical and Biochemical Processes School of Chemistry Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Universidade Federal do Rio de Janeiro Rio de Janeiro Brazil Instituto Nacional de Propriedade Industrial (INPI) Rio de Janeiro Brazil

Anthropic methane emissions can largely be prevented or minimized using technologies that are already available. One such technology is anaerobic digestion (AD), which is used commercially around the world, especially in Europe and the United States, where some challenging targets have been set to diversify the energy mix with more renewable energy. This foresight study was designed to identify which technological solutions out of the many options available for biogas production are attracting most interest, for which purpose patent documents and scientific publications were analyzed. The aim is to identify which raw materials are most attractive for AD and biogas production. It was found that the raw materials that have attracted most research and patenting activity are sludge, sewage, and wastewater, livestock waste, and agriculture waste, which together account for 62% of all the patents filed and 74% of all the scientific publications. The countries most engaged in producing biogas from AD plants are China, Germany, and the United States. We also identified a rising trend in the use of biogas around the world, and a steady increase in the number of patents filed on the subject, especially in Japan and South Korea. This growth is driven, amongst other things, by strategic governmental actions, global environmental pacts, and the realization on the part of industry that anaerobic digestion can be used as an efficient method for treating waste and effluents.

关键词： Anaerobic Digestion Biogas Production Investigative Overview Raw Material

Biliary complications after pediatric liver transplantation: Risk factors, diagnosis and management

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World Journal of Hepatology 2015年第18期7卷 2162-2170页

作者： Flavia H Feier eduardo A da fonseca Joao Seda-Neto Paulo Chapchap Hepatology and Liver Transplantation Hospital Sirio Libanes

The expanded indications of partial grafts in pediatric liver transplantation have reduced waiting list mortality. However, a higher morbidity is observed, including an increased rate of biliary complications(BCs). Factors such as the type of graft, the preservation methods applied, the donor characteristics, the type of biliary reconstruction, and the number of bile ducts in the liver graft influences the occurrence of these complications. Bile leaks and strictures comprise the majority of posttransplant BCs. Biliary strictures require a high grade of suspicion, and because most children have a bileoenteric anastomosis, its diagnosis and management rely on percutaneous hepatic cholangiography and percutaneous biliary interventions(PBI). The success rates with PBI range from 70% to 90%. Surgery is reserved for patients who have failed PBI. BCs in children after liver transplantation have a prolonged treatment and are associated with a longer length of stay and higher hospital costs. However, with early diagnosis and aggressive treatment, patient and graft survival are not significantly compromised.

关键词： Outcomes Live-donor Infants Strictures Bile leaks

Review point on neural stem cells and neurogenic areas of the central nervous system

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Open Journal of Animal Sciences 2013年第3期3卷 242-247页

作者： Erika Toledo da fonseca Ana Carolina Furlanetto Mancanares Carlos eduardo Ambrósio Maria Angélica Miglino Department of Surgery School of Veterinary Medicine and Animal ScienceUniversity of Sao PauloSao PauloBrazil Department of Basic Sciences of the School of Animal Science and Food Engineering University of Sao PauloSao PauloBrazil

The potential applications of neural stem cells (NSC) in the therapy of degenerative and traumatic diseases of the central nervous system (CNS) have aroused great scientific interest. NSCs can be recovered from specific areas of the CNS from fetuses, embryos and from adult brain as well, and under appropriate culture conditions, may be induced to differentiate into the three major neural cell types, neurons, astrocytes and oligodendrocytes. The main neurogenic areas of mammals are the subventricular zone (SVZ) and the dentate gyrus (DG) of the hippocampus, yet other areas of neurogenic potential have been identified, including frontal and parietal cortices, hippocampus and lateral wall of the lateral ventricle. Neural stem cells and differentiated neural cells are usually identified by expression of specific markers, proteins that are expressed by different cell types and/or at different stages of differentiation. The main cell markers are nestin and Sox-2 for undifferentiated NSCs, beta-III tubulin (B-III tubulin) for neurons, Galactocerebroside (GalC) for oligodendrocytes and Glial fibrillary acid protein (GFAP) for astrocytes. In general, the main neurogenic areas, the neurogenic potential of NSC and the morphological and biological characteristics of differentiated neural cells are strikingly similar among species, yet some differences have been reported. This article presents a brief review of NSCs, neurogenic areas and techniques used for their identification and characterization in humans and experimental animals.

关键词： Neurogenesis Neural Stem Cells Subventricular Zone Hippocampus

The Reuse of Historic Buildings as a Preservation Practice

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Journal of Civil Engineering and Architecture 2021年第9期15卷 488-495页

作者： Dirceu Piccinato Junior Cira Lira Borges Caixeta Gabriele Severo da Silva Janaina antunes dos Santos Nauana da Costa Reginato Adilson Giglioli eduardo Marmentini Calgaro Michel dalla Costa Stricto Sensu Post-Graduation Program in Architecture and Urbanism Meridional College-IMEDPasso Fundo/RS 99010-150Brazil

This paper aims to discuss the concept of reuse as a preservation practice for historic *** of the inherent characteristics of architecture is *** is among the necessary conditions for its ***,considering cultural assets and the architectural heritage of different historical moments,currently recognized as depository of artistic,social and memory values,worthy of being preserved,the issue of reuse assumes relationships that go beyond pragmatic aspects to become a cultural *** this end,it can be observed the debate about the reuse of heritage buildings has been gaining prominence in the academic and technical sphere of *** May 2018,the 5th International Forum on Architectural Heritage Brazil-Portugal(FIPA)took place in the city of Rio de Janeiro,*** event had as a study dimension the reuse while a preservationist *** is why the methodology used to structure this text is bibliometrics,in other words,this study was based on papers presented at the event in direct dialogue with the concept under *** this context,it is observed the attribution of a new use,compatible with the characteristics of pre-existing structures,which becomes an important preservation tool.

关键词： Preservationist practices reuse historic buildings

Isolated Autoimmune Orchitis Due to IgG4 Hypersecretion Presenting as Tumor-Like Mass: Case Report and Review of Literature

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Open Journal of Urology 2022年第1期12卷 51-56页

作者： Francisco Marcos da Silva Barroso Flavio antunes de Sousa Paloma Menezes de Souza Gustavo Lopes de Castro Katia Ramos Moreira Leite Monique Freire Santana Roger Arthur da Cunha Alves Gabriela Ayumi Owada Borges Juan eduardo Rios Rodriguez Urology Service Getúlio Vargas University Hospital (HUGV) Manaus Amazonas Brazil General Surgery Service Santa Casa de Ribeir&#227 o Preto Ribeir&#227 o Preto Brazil Sã o Paulo University (USP) Ribeir&#227 o Preto Brazil Faculty of Medicine Federal University of Amazonas (UFAM) Manaus Amazonas Brazil Pathology Department Sírio-Libanes Hospital S&#227 o Paulo Brazil Faculty of Medicine S&#227 o Paulo University (USP) S&#227 o Paulo Brazil Patholgy Service Getúlio Vargas University Hospital (HUGV) Manaus Amazonas Brazil Dr. Heitor Vieira Dourado Tropical Medicine Foundation Manaus Amazonas Brazil Teaching and Research Department Oncology Center Control Foundation (FCECON) Manaus Amazonas Brazil Urology Service Hospital Pronto-Socorro 28 de Agosto Manaus Amazonas Brazil General Surgery Service Getúlio Vargas University Hospital (HUGV) Manaus Amazonas Brazil

Background: IgG4-related disease is a rare autoimmune condition that presents with lymphoplasmacytic infiltrate and fibrosis in the organ affected. Isolated testicle involvement is uncommon and there are only a few cases reported in the literature. Case Presentation: We report a case of isolated chronic orchitis due to IgG4 hypersecretion in a 61-year-old patient that evolved with asymptomatic tumor-like mass growth and was treated with left orchiectomy. Histopathological study revealed orchitis related to IgG4 hypersecretion disease. Conclusion: IgG4-related disease can be manifested as a multi or single-organ disorder. Most diagnoses are made after surgery with histopathological analysis. Most of the cases in literature stand out the difficulty in diagnosis and necessity of high suspicion due to this condition’s similarity with neoplasm presentation.

关键词： Orchitis IgG4-Related Disease Autoimmune Testicle Inflammatory

Nutritional Characteristics of <i>Brachiaria brizantha</i>Cultivars Subjected to Different Intensities Cutting

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American Journal of Plant Sciences 2014年第13期5卷 1961-1972页

作者： Kátia Aparecida de Pinho Costa eduardo da Costa Severiano Gustavo André Simon Patrícia Soares Epifanio Alessandro Guerra da Silva Raoni Ribeiro Guedes fonseca Costa Charles Barbosa Santos Carlos Ribeiro Rodrigues Goiano Federal Institute Rio Verde Brazil University of Rio Verde Rio Verde Brazil

This study evaluated the nutritional characteristics of Brachiaria brizantha cultivars subjected to three cutting intensities in the course of one year. The experiment was conducted at the University of Rio Verde. The experiment was performed as a randomized 3 × 3 factorial in complete block design with three replications and repeated measures in the time. Three Brachiaria brizantha cultivars (Marandu palisadegrass, Xaraes palisadegrass, and Piata palisadegrass), were tested at three cutting intensities (10, 20, and 30 cm sward height). The evaluations were conducted on the same plots throughout one year and during all four seasons (autumn, winter, spring, and summer). The results showed that the Piata palisadegrass had the best chemical composition compared to the Marandu palisadegrass and Xaraes palisadegrass. The management of Brachiaria brizantha cultivars at the lowest residual height (10 cm) affected the nutritional value of these feed grasses. Seasonality also influenced the nutritional value of these forages.

关键词： Marandu Palisadegrass Piata Palisadegrass Sward Height Xaraes Palisadegrass