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Pain in Non-Athlete Patients Undergoing Hip Arthroscopy for Femoroacetabular Impingement and Hip Labral Tears: A Longitudinal Study

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Health 2023年第9期15卷 990-1002页

作者： Kaori sano Yuko Uesugi Hidetsugu Ohara Graduate School of Health Sciences Kobe University Kobe Japan Department of Nursing Kinjo Gakuin University Nagoya Japan Department of Orthopedic Surgery Hirakata City Hospital Hirakata Japan

Background: Pain in patients with orthopedic problems is an important aspect of surgical evaluation. However, the effect on the quality of life depends not only on the degree of pain but also on its type. Hip arthroscopy has been performed for hip joint symptoms caused by femoroacetabular impingement (FAI) and hip labrum tears. However, the degree and type of pain after hip arthroscopy remains unknown. Objective: This study aimed to clarify the degree and type of pain during 6 months after hip arthroscopy. Methods: Non-athlete patients aged 20 - 65 years who underwent hip arthroscopy between December 2018 and October 2019 participated in a questionnaire survey before hospitalization and at 1, 3, and 6 months after surgery. The questionnaire comprised the Japanese Orthopaedic Association Hip-Disease Evaluation Questionnaire (JHEQ) for quality of life, International Physical Activity Questionnaire (IPAQ) for activities, and the Short-Form McGill Pain Questionnaire (SF-MPQ-2) for pain. Results: The analysis included 10 patients (men: 4, women: 6, mean age: 38 ± 8.6 years, FAI: 6 cases, hip labrum tears: 4 cases). The average time from symptom onset to surgery was 26.9 ± 19.0 months. The analysis from before surgery to 6 months after surgery showed improvement over time in all scale scores (JHEQ, IPAQ, and SF-MPQ-2). The degree of pain was significantly improved based on the JHEQ visual analog scale evaluation (P = 0.019) 3 months after surgery. Significant improvement in intermittent pain (P = 0.011) based on SF-MPQ-2 was noted 3 months after surgery;however, no significant improvement in continuous pain was noted. Conclusions: Patients who underwent hip arthroscopy showed significant improvements in the degree of pain and type of intermittent pain from before surgery to 3 months after surgery, however, no change was observed in continuous pain.

关键词： Hip Arthroscopy Orthopedic Quality of Life Type of Pain

Controlled synthesis of magnetic carbon nanoparticles via glycerol/ferrocene co-pyrolysis with magnetic induction

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Particuology 2018年第2期16卷 9-16页

作者： Konrat Kerdnawee Noriaki sano Hajime Tamon Tawatchai Charinpanitkul Center of Excellence in Particle Technology Department of Chemical Engineering Faculty of Engineering Chulalongkorn University Bangkok Thailand Department of Chemical Engineering Graduate School of Engineering Kyoto University Kyoto Japan

We performed a controlled synthesis of magnetic carbon nanoparticles （M-CNPs） via co-pyrolysis of glycerol and ferrocene with magnetic induction. The morphology of the synthesized M-CNPs was confirmed by transmission electron microscopy, and thermogravimetric analysis was used to analyze the carbon and Fe contents. M-CNPs that responded to magnetic stimulation were also examined with an AC-magnetic susceptibility analyzer. Our investigations on the influence of synthesis temperature in the range 700-1000℃ suggested that for an initial glycerol to ferrocene weight ratio of 3：1 and a temperature of 800 ℃ gave the highest yield of M-CNPs. Comparing the synthesis with and without magnetic induction, the controlled synthesis under the influence of magnetic induction shows promise as a method for producing high quality M-CNPs in high yields.

关键词： Carbon nanoparticle Glycerol Co-pyrolysis Magnetic induction

Optimal resection of gastric bronchogenic cysts based on anatomical continuity with adherent gastric muscular layer: A case report

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World Journal of Gastrointestinal Surgery 2023年第6期15卷 1216-1223页

作者： Masayoshi Terayama Koshi Kumagai Hiroshi Kawachi Rie Makuuchi Masaru Hayami Satoshi Ida Manabu Ohashi Takeshi sano Souya Nunobe Department of Gastroenterological Surgery Gastroenterological CenterCancer Institute HospitalJapanese Foundation for Cancer ResearchTokyo 135-8550Japan Department of Pathology Cancer Institute HospitalJapanese Foundation for Cancer ResearchTokyo 135-8550Japan

BACKGROUND Bronchogenic cysts are congenital lesions requiring radical resection because of malignant ***,a method for the optimal resection of these cysts has not been completely *** SUMMARY Herein,we presented three patients with bronchogenic cysts that were located adjacent to the gastric wall and resected *** cysts were detected incidentally with no symptoms and the preoperative diagnosis was challenging to obtain via radiological *** on laparoscopic findings,the cyst was attached firmly to the gastric wall and the boundary between the gastric and cyst walls was difficult to ***,resection of cysts alone caused cystic wall injury in Patient ***,the cyst was resected completely along with a part of the gastric wall in Patient *** examination revealed the final diagnosis of bronchogenic cyst and revealed that the cyst wall shared the muscular layer with the gastric wall in Patients 1 and *** Patient 3,the cyst was located adjacent to the gastric wall but histopathologically originated from diaphragm rather than *** the patients were free from *** The findings of this study state that a safe and complete resection of bronchogenic cysts required the adherent gastric muscular layer or full-thickness dissection,if bronchogenic cysts are suspected via pre-and/or intraoperative findings.

关键词： Bronchogenic cysts Laparoscopic resection Gastric wall Muscular layer Case report

Sporadic fundic gland polyps with dysplasia or carcinoma:Clinical and endoscopic characteristics

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World Journal of Gastrointestinal Oncology 2021年第7期13卷 662-672页

作者： Wataru sano Fumihiro Inoue Daizen Hirata Mineo Iwatate Santa Hattori Mikio Fujita Yasushi sano Gastrointestinal Center Sano HospitalKobe 655-0031HyogoJapan

Fundic gland polyps(FGPs)are the most common gastric polyps and have been regarded as benign lesions with little malignant potential,except in the setting of familial adenomatous ***,in recent years,the prevalence of FGPs has been increasing along with the widespread and frequent use of proton pump inhibitors(PPIs).To date,several cases of FGPs with dysplasia or carcinoma(FGPD/CAs)have been *** this review,we evaluated the clinical and endoscopic characteristics of sporadic FGPD/*** of the patients with sporadic FGPD/CAs were middle-aged women receiving PPI therapy and without Helicobacter pylori(***)*** of the sporadic FGPD/CAs occurred in the body of the stomach and were sessile and small with a mean size of 5.4 *** sporadic FGPs with carcinoma showed redness,irregular surface structure,depression,or erosion during white light observation and irregular microvessels on the lesion surface during magnifying narrow-band *** addition,sporadic FGPs,even with dysplasia,are likely to progress to cancer ***,frequent endoscopy is not required for patients with sporadic ***,histopathological evaluation is necessary if endoscopic findings different from ordinary FGPs are observed,regardless of their *** the future,the prevalence of FGPs is expected to further increase along with the widespread and frequent use of PPIs and decreasing infection rate of ***,it is unclear whether FGPD/CAs will also increase in the same way as ***,the trends of these lesions warrant further attention in the future.

关键词： Sporadic Fundic gland polyp Dysplasia Carcinoma Proton pump inhibitor Helicobacter pylori

Serrated polyps of the colon and rectum:Remove or not?

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World Journal of Gastroenterology 2020年第19期26卷 2276-2285页

作者： Wataru sano Daizen Hirata Akira Teramoto Mineo Iwatate Santa Hattori Mikio Fujita Yasushi sano Gastrointestinal Center Sano HospitalHyogo 655-0031Japan

In recent years,the serrated neoplasia pathway where serrated polyps arise as a colorectal cancer has gained considerable attention as a new carcinogenic *** serrated polyps are histopathologically classified into hyperplastic polyps(HPs),sessile serrated lesions,and traditional serrated adenomas;in the serrated neoplasia pathway,the latter two are considered to be *** western countries,all colorectal polyps,including serrated polyps,apart from diminutive rectosigmoid HPs are ***,in Asian countries,the treatment strategy for colorectal serrated polyps has remained ***,in this review,we described the clinicopathological features of colorectal serrated polyps and proposed to remove HPs and sessile serrated lesions≥6 mm in size,and traditional serrated adenomas of any size.

关键词： Hyperplastic polyp Sessile serrated adenoma/polyp Sessile serrated lesion Traditional serrated adenoma Cytological dysplasia Cryptal dysplasia

Melatonin Enhances Object Recognition Memory through Melatonin MT1 and MT2 Receptor-Mediated and Non-Receptor-Mediated Mechanisms in Male Mice

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Journal of Behavioral and Brain Science 2022年第12期12卷 640-657页

作者： Masahiro sano Hikaru Iwashita Atsuhiko Hattori Atsuhiko Chiba Department of Materials and Life Sciences Faculty of Science and Technology Sophia University Tokyo Japan Department of Biology College of Liberal Arts and Sciences Tokyo Medical and Dental University Chiba Japan

Melatonin (MEL) has been reported to have acute enhancing effects on some aspects of cognition. Recently, we revealed that N1-acetyl-5-methoxyquinuramine (AMK), a brain metabolite of MEL, is much more potent than MEL in converting short-term memory (STM) to long-term memory (LTM) with a single administration immediately after the acquisition trial of the novel object recognition (NOR) task. These data suggest that the memory-enhancing effects of MEL may be mediated by mechanisms independent of the activation of MEL MT1 and MT2 receptors. In the present study, we examined the contribution of MT1 and MT2 receptor-mediated and non-receptor-mediated mechanisms to the acute memory-enhancing effects of MEL using NOR task. Mice were administered with either MEL, AMK, or a highly selective MT1/MT2 receptor agonist ramelteon (RAM) immediately after the acquisition trial and the effects of varying doses of these drugs on both STM and LTM performance were compared. We found that both AMK and RAM were more potent than MEL in both facilitating STM and promoting LTM formation. We also found that pretreatment with luzindole, a MT1/MT2 receptor antagonist, markedly suppressed only the effects of RAM. These results suggest that acutely administered MEL enhances NOR memory through both MT1 and MT2 receptor-mediated and non-receptor-mediated mechanisms.

关键词： Melatonin N1-Acetyl-5-Methoxykynuramine Ramelteon Novel Object Recognition Memory Melatonin Receptors

Smart Processing in Materials Tectonics:Fabrication of Photonic Crystals for Terahertz Wave Control by Using Micro-Stereolithography

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Tsinghua Science and Technology 2009年第S1期14卷 160-163页

作者： Soshu Kirihara Daisuke sano Masaru Kaneko Smart Processing Research Center Joining and Welding Research Institute Osaka University Osaka 567-0047 Japan Smart Processing Research Center Joining and Welding Research Institute Osaka University Division of Sustainable Energy and Environmental Engineering Graduate School of Engineering Osaka University

Photonic crystals with three-dimensional dielectric structures were fabricated to control terahertz waves effectively by using micro-stereolithography of a CAD/CAM process. The photonic crystals with a diamond structure composed of acrylic lattice with nanosized alumina particles were fabricated. Dense alumina structures were obtained by successive dewaxing and sintering in an air atmosphere. The electromagnetic wave properties of these samples were measured by using a terahertz spectroscopy device. The micro periodic structures exhibited perfect band gaps in the terahertz range. To control terahertz waves, micrometer sized electromagnetic devices for cavities, filters, and antennas will be necessary.

关键词： diamond photonic crystal band gap micro-stereolithography terahertz wave

New application of endocytoscope for histopathological diagnosis of colorectal lesions

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World Journal of Gastrointestinal Endoscopy 2022年第8期14卷 495-501页

作者： Fumihiro Inoue Daizen Hirata Mineo Iwatate Santa Hattori Mikio Fujita Wataru sano Tamotsu Sugai Hiroshi Kawachi Kazuhito Ichikawa Yasushi sano Gastrointestinal Center and Institute of Minimally-invasive Endoscopic Care(i-MEC) Sano HospitalKobe 655-0031HyogoJapan Molecular Diagnostic Pathology Iwate Medical University School of MedicineShiwa-gun 028-3694IwateJapan Department of Pathology Cancer Institute Hospital of Japanese Foundation for Cancer ResearchKoto 135-8550TokyoJapan Department of Pathology Noda HospitalNoda 270-0237ChibaJapan

BACKGROUND The endocytoscope with ultra-high magnification(x 520)allows us to observe the cellular structure of the colon epithelium during colonoscopy,known as virtual *** hypothesized that the endocytoscope could directly observe colorectal histopathological specimens and store them as endocyto-pathological images by the endoscopists without a microscope,potentially saving the burden on *** To assess the feasibility of endocyto-pathological images taken by an endoscopist as adequate materials for histopathological *** Three gastrointestinal pathologists were invited and asked to diagnose 40 cases of endocyto-pathological images of colorectal *** case contained seven endocyto-pathological images taken by an endoscopist,consisting of one loupe image,three low-magnification images,and three ultra-high magnification *** participants chose hyperplastic polyp or low-grade adenoma for 20 cases of endocyto-pathological images(10 hyperplastic polyps,and 10 Low-grade adenomas in conventional histopathology)in study 1 and high-grade adenoma/shallow invasive cancer or deep invasive cancer for 20 cases[10 tumor in situ/T1a and 10 T1b]in study *** investigated the agreement between the histopathological diagnosis using the endocyto-pathological images and conventional histopathological *** Agreement between the endocyto-pathological and conventional histopathological diagnosis by the three gastrointestinal pathologists was 100%(95%CI:94.0%–100%)in studies 1 and *** interobserver agreement among the three gastrointestinal pathologists was 100%,and theκcoefficient was 1.00 in both *** Endocyto-pathological images were adequate and reliable materials for histopathological diagnosis.

关键词： Cancer Colon Endocytoscopy Histopathology Specimen

Usefulness of Detailed Analysis with Operative Procedure of Total Laparoscopic Hysterectomy (TLH) Done a Single Surgeon, to Master the Surgical Technique of TLH and Gain Higher Proficiency

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Open Journal of Obstetrics and Gynecology 2022年第11期12卷 1183-1190页

作者： Tsutomu Muramoto Shin Takenaka Ryo Koike Megumi sano Kyosuke Kamijo Reproductive Center Nagano Municipal Hospital Nagano Japan Department of Obstetrics and Gynecology Showa University Fujigaoka Hospital Yokohama Japan

Objective: To analyze the relationship between the numbers of cases experienced and the operation time for a single surgeon aiming to master the TLH surgical technique. Material and Methods: Retrospective data analysis of women who underwent TLH for benign diseases between April, 2014 and March, 2016 was conducted by a single surgeon in a single hospital (Showa University of Fujigaoka Hospital). We divided the main procedures of the TLH operation into five sections, and measured the time required for each section. These cases were divided into three groups, group 1, 2, and 3. Results: There were 54 cases of TLH over two years for a single surgeon, and 21 cases that included essential operative procedures were divided into three groups of seven cases each. The average duration of the surgery (min.) was 178.3 ± 48.2 in the group 1, 128.3 ± 15.6 in the group 2, and 111.3 ± 15.9 in the group 3. A significant reduction in the required time was observed between group 1, 2, and 3 groups. As the number of cases increased, the operation time became statistically significantly shorter for every section except B and D. The skill growth rate was different at each section. Conclusion: For a single surgeon, as the number of surgical cases increased, we recognized the increased skill with the procedure in every section and the rate of skill growth differed for different sections. The difference of growth rate for each section implied that the number of operative cases required for a surgeon in each section was different.

关键词： Total Laparoscopic Hysterectomy on the Job Training Learning Curve Surgical Technique of TLH