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Open Journal of Modern Neurosurgery 2014年第4期4卷 163-168页

作者： Ramón Navarro edison J. Cano Leonardo B. C. Brasiliense Guilherme Dabus Ricardo A. Hanel Department of Neurosurgery Mayo Clinic Jacksonville FL USA Interventional Neuroradiology Baptist Cardiac and Vascular Institute Miami USA

Purpose: Flow diversion is a relatively novel technique to treat some intracranial aneurysms. With new techniques, unusual complications can occur. We described a case of Pipeline Embolization Device (PED) migration, strategy for its recognition, and a technical point to prevent its occurrence. Publication of these rare events is important to make physicians aware of potential complications. Methods: A patient with a previously coiled giant superior cerebellar aneurysm presented with brainstem compression symptoms. Imaging verified progressive aneurysm growth. A decision was made to treat the aneurysm with PED. Results: Development of new neurologic symptoms prompted a computed tomography that showed hydrocephalus. An angiogram also showed recanalization of the aneurysm secondary to upward migration/retraction of the flow diverter. A ventriculo-peritoneal shunt was implemented and planning for placement of a second flow diverter was made. Unfortunately, the patient expired while waiting for the endovacular intervention. Conclusions: PED migration may occur even after correct placement of the device. Early recognition of this complication is essential. When clinical changes occur, it is paramount that this uncommon, but potentially deadly, complication is suspected. Appropriate sizing and deployment technique are important for the long-term stability of the device.

关键词： Giant Intracranial Aneurysm Endovascular Treatment Flow Diverter Complication Migration

<i>FAS</i>-670 Gene Promoter Region Polymorphism in Cervical Intraepithelial Neoplasia Grade 3 (CIN 3) and Invasive Cervical Cancer

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Journal of Cancer Therapy 2015年第5期6卷 434-445页

作者： edison Fedrizzi Flavio Zucchi Sylvia Brenna Cristina Valletta de Carvalho Fabricio Silva Ana Massad Costa Ismael Guerreiro da Silva Federal University of Santa Catarina Florianópolis Brazil

The human papillomavirus (HPV) is the etiologic agent of genital cancer, but alone it is incapable of inducing oncogenesis. Rather, progression to invasive lesions is associated with host immunity and interference in the process of cellular apoptosis. Among the several genes involved in cell death, theFAS gene appears to be an important factor. The aim of this study was to evaluate whether there is an association between polymorphisms of the FAS-670 gene promoter region and preinvasive and invasive lesions of the cervix. The FAS gene was evaluated for the presence of polymorphisms using polymerase chain reaction and restriction fragment length polymorphism techniques in 225 blood samples for the control group, as well as cervical tissue from patients with cervical intraepithelial neoplasia grade 3 (CIN 3;75 cases) or invasive carcinoma (214 cases). The AG genotype of the FAS-670 gene promoter region was significantly more frequent in women with CIN 3, with an estimated risk of three times (OR = 3.0). No difference, however, was observed in the control group and women with cervical cancer. In women with cancer, the genotypes were similar in the different histological types and degree of tumor differentiation. Assessing allelic distribution (A or G), we observed no difference in frequency of genotypes in studied groups. These data suggest that polymorphism of the promoter region of the FAS-670 gene is associated with increased risk of CIN 3, but not for invasive cancer of the cervix.

关键词： FAS Genetic Polymorphism CIN 3 Uterine Cervical Neoplasms Apoptosis

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展场花絮

微型计算机 2008年第13期28卷 9-9页

作者： edison

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针对未来世界而准备的“概念”技术

微型计算机 2008年第13期28卷 8-8页

作者： edison

感知计算与自动互联在展会现场，英特尔演示了一个可自动感知用户需求，自动搜索和识别周边无线设备的虚拟家居环境（基于Cliffside技术）。它由无线DC，迅驰笔记本电脑，无线打印机，无线投影机，无线遥控器等部分组成。当用户手拿DC... 详细信息

感知计算与自动互联在展会现场，英特尔演示了一个可自动感知用户需求，自动搜索和识别周边无线设备的虚拟家居环境（基于Cliffside技术）。它由无线DC，迅驰笔记本电脑，无线打印机，无线投影机，无线遥控器等部分组成。当用户手拿DC拍照，或者从屋外回到室内时，

关键词：技术迅驰笔记本电脑用户需求自动感知无线设备无线打印机无线投影机

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β-片层结构中一个错误的延续

生命的化学 1991年第4期 33-34页

作者： Arthur S. edison 杨忠慧

在Linus Pauling著的《化学键的本质》一书中,我发现里面关于β-片层结构的模型错了,无论是平行结构还是反平行结构都有错误,而这一错误竟通过各大专院校普遍使用的教科书得以延续30年之久! 在威斯康辛大学学习时,我曾把Creighton

关键词：片层结构氨基酸氨基羧酸《化学键的本质》片层结构模型

Hematology and blood serum chemistry reference intervals for children in Iganga district of Uganda

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Health 2013年第8期5卷 1261-1267页

作者： Fred Kironde Musa Sekikubo Halima Naiwumbwe Fatuma Namusoke William Buwembo Steven Kiwuwa Brenda Oketch Ramadhani Noor Roma Chilengi edison Mworozi Mark Kaddumukasa African Malaria Network Trust Dar-es Salaam Tanzania Centre for Infectious Disease Research in Zambia (CIDRZ) Lusaka Zambia Makerere University College of Health Sciences Kampala Uganda

In this study, normal ranges for hematology and serum biochemistry in children aged 1 to 5 years inUgandawere determined. By a cross-sectional study, 1168 children from Iganga, a prospective site for clinical trials in Uganda, were screened. From 1168 households, 460 children were selected for enrollment, while 600 (58%) were excluded because of either a history of fever in the previous 24 hours, presence of asexual malaria parasites in the peripheral blood or presence of fever. Accordingly, 460 children (39.4%) of median age = 3 years were enrolled in the baseline study. While the lower limits of hemoglobin, hematocrit levels, mean corpuscular volume and platelet counts for the Ugandan children were found to be less than conventional reference values of Caucasisan children, the white blood cell count reference values were higher than the international intervals. On the other hand, the upper limits of the reference intervals for serum transaminases, bilirubin, creatinine, urea, total protein and albumin in sera of the Ugandan children were higher than the corresponding values for a Caucasian pediatric population. This study showed that, if hematology test results of the Ugandan children were assessed against “imported” international reference values, up to 44.6% of the study participants would have been excluded from clinical trials or would have been reported as adverse events in such trials. The present study was not only the first report of serum biochemistry reference ranges for children aged one to five years in Uganda but also one of very few such studies in Africa.

关键词： Normal Intervals Reference Uganda Children Hematology Serum Biochemistry Iganga

Changes in Soil Carbon Stocks under Integrated Crop-Livestock-Forest System in the Brazilian Amazon Region

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Agricultural Sciences 2017年第9期8卷 904-913页

作者： Marcela C.G.da Conceicao Eduardo S.Matos edison D.Bidone Renato de A.R.Rodrigues Renato C.Cordeiro Universidade Federal Fluminense NiteróiBrazil Embrapa Agrossilvipastoril SinopBrazil Embrapa Solos Rio de JaneiroBrazil

Several studies indicate that the use of integrated production systems, such as integrated crop-livestock-forest systems (ICLF), improves the quality of the soil and consequently the sequestration of organic carbon in the soil. In this way, this work aims to evaluate the carbon stocks in soil under different management systems in the Cerrado/Amazonia transition zone, namely: ICLF, no-tillage, pasture and eucalyptus plantation. For this, two soil samplings were done in 2011 and 2014, in the 0 - 5, 5 - 10 and 10 - 30 cm layers. Soil carbon and nitrogen stocks were analyzed. ICLF system was the treatment that obtained the highest percentage of carbon gain (7.8%) after three years of establishment which represents to an increase of 5.5 Mg·ha-1. Management systems, such as ICLF, with minimal soil disturbance combined with crop rotations that contribute to the quantity and quality of residues input, increase soil organic matter content. Carbon stock data show the potential of ICLF systems to increase soil carbon stocks.

关键词： Agriculture Soil Carbon ICLF Soil Management

Impact of cytomegalovirus reactivation just before liver transplantation:A prospective cohort study

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World Journal of Gastrointestinal Pathophysiology 2021年第3期12卷 51-58页

作者： Claudio Marcel B Stadnik Cassia Ferreira B Caurio edison M Rodrigues-Filho Wagner L Nedel Guido PC Cantisani Maria L Zanotelli Alessandro C Pasqualotto Infection Control Department Santa Casa de Misericordia de Porto AlegrePorto Alegre 90075075RSBrazil Molecular Biology Laboratory Santa Casa de Misericordia de Porto AlegrePorto Alegre 90075075RSBrazil Intensive Care Santa Casa de Misericordia de Porto AlegrePorto Alegre 90075075RSBrazil Liver Transplant Unit Santa Casa de Misericordia de Porto AlegrePorto Alegre 90075075RSBrazil Infectious Diseases Unit Universidade Federal de Ciencias da Saude de Porto AlegrePorto Alegre 90035075RSBrazil

BACKGROUND Cytomegalovirus(CMV)is the most common viral pathogen after liver transplantation(LT).Although reactivation of CMV infection is generally described in the context of immunosuppression,it has also been described in critically ill immunocompetent patients including cirrhotic *** To determine the incidence of reactivated CMV prior to *** This was a prospective cohort study evaluating adult patients who underwent LT between 2014 and 2016.A plasma sample was obtained from all patients for CMV quantitative real-time PCR testing right before *** were followed for at least 1 year to assess the following outcomes:Incidence of CMV infection,organ rejection and overall *** A total of 72 patients were *** patients died before transplantation,thus 68 patients were followed up for a median of 44 mo(20-50 mo).In 23/72 patients(31.9%)CMV was reactivated before ***-transplantation,16/68(23.5%)patients had CMV infection and that was significantly associated with the recipient being CMV negative and a CMV-positive *** CMV reactivation was not associated with overall mortality(log rank:0.9).CONCLUSION This study shows that CMV infection is common in patients with chronic liver disease just before LT,but the clinical impact of this infection seems to be negligible.

关键词： Liver transplantation Cytomegalovirus infection Quantitative real-time PCR Risk factors Liver cirrhosis Molecular biology

为自动驾驶搭建精准数据平台——访北京冲浪科技有限公司CEO贺纯洁

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中国商界 2019年第8期 118-121页

作者：陈平贺纯洁不详北京冲浪科技有限公司

打开贺纯洁的朋友圈,其中一条是在5月30日晚22时18分,动感的图片上标记着"10KM",还配了留言best season comes。这个热爱运动、热爱生活、来自大连的商界新锐为自己的公司起名叫冲浪科技,寓意乘风破浪去实现社会价值的最大化。

关键词：数据平台纯洁公司科技冲浪 CEO 北京驾驶

Highly Efficient and Stable Hydrogen Production in All pH Range by Two-Dimensional Structured Metal-Doped Tungsten Semicarbides

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Research 2019年第1期2019卷 991-1004页

作者： edison H.Ang Khang N.Dinh Xiaoli Sun Ying Huang Jun Yang Zhili Dong Xiaochen Dong Wei Huang Zhiguo Wang Hua Zhang Qingyu Yan Energy Research Institute Interdisciplinary Graduate SchoolNanyang Technological University637553Singapore Centre for Programmable Materials School of Materials Science and EngineeringNanyang Technological University639798Singapore Institute of Advanced Materials Nanjing Tech UniversityNanjing 210000China School of Physical Electronics University of Electronic Science and Technology of ChinaChengdu 610054China Department of Chemistry City University of Hong KongKowloonHong Kong

Transition-metal-doped tungsten semicarbide nanosheets(M-doped W_(2)C NSs,M=Fe,Co,and Ni)have been synthesized through carburization of the mixture of tungsten trioxide,polyvinylpyrrolidone,and metal *** nanosheets grow directly on the W mesh and have the lateral dimension of several hundreds of nm to a few�m with a thickness of few tens *** is demonstrated that the M-doped W_(2)C NSs exhibit superior electrocatalytic activity for hydrogen evolution reaction(HER).Impressively,the Nidoped W_(2)C NSs(2 at%Ni)with the optimized HER activity show extremely low onset overpotentials of 4,9,and 19 mV and modest Tafel slopes of 39,51,and 87 mV dec−1 in acidic(pH=0),neutral(pH=7.2),and basic(pH=14)solutions,respectively,which is close to the commercial Pt/C *** functional theory(DFT)calculations also demonstrate that the Gibbs free energy for H adsorption of Ni-W_(2)C is much closer to the optimal valueG_(H∗)=-0.073 eV as compared to-0.16 eV of W_(2)***,nearly 100%Faradaic efciency and long-term stability are obtained in those *** realization of highly tolerant metal semicarbide catalyst performing on par with commercial Pt/C in all range of pH ofers a key step towards industrially electrochemical water splitting.

关键词： Highly closer realization