检索结果-南通市图书馆

Mapping global research trends: Nutrition associations with nonalcoholic fatty liver disease - a Scopus bibliometric analysis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第24期30卷 3106-3119页

作者： Muna Shakhshir Sa'ed H Zyoud department of Nutrition An-Najah National University HospitalNablus 44839Palestine department of Public Health College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Information Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Several bibliometric analyses have been carried out to identify research hotspots and trends in nonalcoholic fatty liver disease(NAFLD)***,there are still significant knowledge gaps that must be filled to advance our understanding of and ability to treat *** To evaluate,through bibliometric and visual analysis,the current status of related research,related research frontiers,and the developmental trends in the field of diet and *** We retrieved publications about diet and NAFLD published between 1987 and 2022 from ***,we used VOSviewer 1.6.20 to perform bibliometric analysis and *** We found a total of 1905 studies,including 1637(85.93%)original articles and 195(10.24%)reviews,focused on the examination of NAFLD and its correlation with diet that were published between 1987 and *** the remaining five types of documents,38 were letters,notes,editorials,meeting minutes,or brief surveys,representing 1.99%of the total *** countries with the most publications on this topic were China(n=539;28.29%),followed by the United States(n=379;19.90%),Japan(n=133;6.98%),and South Korea(n=127;6.6%).According to the citation analysis,the retrieved papers were cited an average of 32.3 times and had an h-index of 106,with 61014 total *** two main clusters on the map included those related to:(1)Inflammation and oxidative stress;and(2)Dietary interventions for *** This was the first study to use data taken from Scopus to visualize network mapping in a novel bibliometric analysis of studies focused on diet and *** 2017,the two domains that received the most attention were“dietary interventions for NAFL”’and“‘inflammation and oxidative stress implicated in NAFLD and its correlation with diet.”We believe that this study provides important information for academics,dietitians,and doctors,and that additional research on dietary interventions and NAFLD is warranted.

关键词： Dietary Nutrition Bibliometric Nonalcoholic fatty liver Scopus VOSviewer

Perspectives for delivery of therapeutics by extravasation of biodegradable microspheres in the brain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第5期19卷 969-970页

作者： Anne-Eva van der Wijk ed VanBavel Amsterdam UMC location University of Amsterdam Department of Biomedical Engineering and PhysicsAmsterdamThe Netherlands Amsterdam Neuroscience Neurovascular Disorders ProgramAmsterdamThe Netherlands Amsterdam Cardiovascular Sciences Microcirculation ProgramAmsterdamThe Netherlands

development of therapeutics for brain diseases has remained challenging,in particular due to the difficulty of passing the blood-brain *** a result,the current arsenal of therapeutics targeting the brain is limited to small,lipid-soluble drugs and there is a lack of options for treating neuroblastomas,Alzheimer’s disease,and many other devastating *** the advances in strategies for crossing the blood-brain barrier such as the use of nanoparticles(Hersh et al.,2022;Duan et al.,2023),such delivery systems have not yet reached clinical ***,novel platforms for the transport of therapeutics across the blood-brain barrier remain highly *** specifically holds for large molecules such as monoclonal antibodies and recombinant proteins,as well as nucleotide-based therapeutics and cell *** efforts in this field are increasing exponentially,with thousands of publications in the last few years.

关键词： therapeutics holds spite

Co-Optimization of Behind-the-Meter and Front-of-Meter Value Streams in Community Batteries

在线全文

学校读者我要写书评

暂无评论

Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 334-345页

作者： Carmen Bas Domenech Antonella Maria de Corato Pierluigi Mancarella University of Melbourne Parkville 2010VictoriaAustralia department of Electrical and Electronic Engineering The University of ManchesterManchesterU.K. IEEE

Community batteries(CBs)are emerging to support and even enable energy communities and generally help consumers,especially space-constrained ones,to access potential techno-economic benefits from storage and support local grid ***,the economic viability of CB projects is often *** this regard,typical feasibility studies assess CB value for behind-the-meter(BTM)operation or whole-sale market participation,i.e.,front-of-meter(FOM).This work proposes a novel techno-economic operational framework that allows systematic assessment of the different options and introduces a two-meter architecture that co-optimizes both BTM and FOM benefits.A real CB project application in Australia is used to demonstrate the significant two-meter co-optimization opportunities that could enhance the business case of CB and energy communities by multi-service provision and value stacking.

关键词： Behind-the-meter community battery distributed energy resource(deR) energy community front-of-meter value stacking

A Multilayer Perceptron Artificial Neural Network Study of Fatal Road Traffic Crashes

在线全文

学校读者我要写书评

暂无评论

Journal of Data Analysis and Information Processing 2024年第3期12卷 419-431页

作者： ed Pearson III Aschalew Kassu Louisa Tembo Oluwatodimu Adegoke department of Electrical Engineering & Computer Science Alabama A&M University Normal AL USA department of Mechanical Civil Engineering & Construction Management Alabama A&M University Normal AL USA department of Mathematics and Computer Science Alabama State University Montgomery AL USA

This paper examines the relationship between fatal road traffic accidents and potential predictors using multilayer perceptron artificial neural network (MLANN) models. The initial analysis employed twelve potential predictors, including traffic volume, prevailing weather conditions, roadway characteristics and features, drivers’ age and gender, and number of lanes. Based on the output of the model and the variables’ importance factors, seven significant variables are identified and used for further analysis to improve the performance of models. The model is optimized by systematically changing the parameters, including the number of hidden layers and the activation function of both the hidden and output layers. The performances of the MLANN models are evaluated using the percentage of the achieved accuracy, R-squared, and Sum of Square Error (SSE) functions.

关键词： Artificial Neural Network Multilayer Perceptron Fatal Crash Traffic Safety

Mapping the global research landscape on nonalcoholic fatty liver disease and insulin resistance:A visualization and bibliometric study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2024年第6期16卷 951-965页

作者： Sa'ed H Zyoud Omar E Hegazi Samer O Alalalmeh Muna Shakhshir Faris Abushamma Shadi Khilfeh Samah W Al-Jabi department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine College of Pharmacy and Health Sciences Ajman UniversityAjman 346United Arab Emirates department of Nutrition An-Najah National University HospitalNablus 44839Palestine department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine department of Urology An-Najah National University HospitalNablus 44839Palestine department of Gastroenterology Hepatology and EndoscopyAn-Najah National University HospitalNablus 44839Palestine

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic *** it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and *** To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and *** This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to *** search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and *** software was used to visualize research trends,collaborations,and key thematic *** analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited *** This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and *** search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)*** most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflamma

关键词： Nonalcoholic fatty liver disease Insulin resistance Bibliometric Visualization

Geochemical fingerprints and hydrocarbon potential of Paleocene mudrocks in the Tano Basin, Ghana: insights from biomarkers and stable carbon isotopes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Geochimica 2024年第2期43卷 255-279页

作者： Kojo Amoako Nancy Pearl Osei-Boakye Ningning Zhong N’Guessan Francois de Sales Konan Gordon Foli Prince Opoku Appau Clifford Fenyi Ebenezer Apesegah Research Group for Marine Geochemistry(ICBM-MPI Bridging Group) Institute for Chemistry and Biology of the Marine Environment(ICBM)Carl von Ossietzky University OldenburgAmmerlander Heerstr.26129 OldenburgGermany State Key Laboratory of Petroleum Resources and Prospecting College of GeosciencesChina University of PetroleumBeijing 102249China department of Geological Engineering Faculty of Civil and Geo-EngineeringKwame Nkrumah University of Science and TechnologyKumasiGhana Ghana National Gas Company 225 Osibisa CloseAirport WestAccraGhana Petroleum Corporation GNPCPMBPetroleum HouseTemaGhana

The Paleocene mudrocks in Ghana’s Tano Basin have received limited attention despite ongoing efforts to explore hydrocarbon resources.A thorough geochemical analysis is imperative to assess these mudrocks’petroleum generation potential and formulate effective exploration *** this study,a comprehensive geochemical analysis was carried out on ten Paleocene rock cuttings extracted from TP-1,a discovery well within the Tano *** analytical techniques,including total organic carbon(TOC)analysis,Rock–Eval pyrolysis,gas chromatography-mass spectrometry,and isotope ratio-mass spectrometry,were employed to elucidate their hydrocar-bon potential and organic ***ﬁndings in this study were subsequently compared to existing geochemical data on Paleocene source rocks in the South Atlantic marginal *** results indicated that the Paleocene samples have TOC content ranging from 0.68 to 2.93 wt%.The prevalent kerogen types identiﬁed in these samples were Type Ⅱ and Type Ⅲ.Molecular and isotope data suggest that the organic matter found in the Paleocene mudrocks can be traced back to land plants and lower aquatic *** mudrocks were deposited in a transi-tional environment withﬂuctuating water salinity,charac-terized by sub-oxic redox *** indices,both bulk and molecular,indicated a spectrum of maturity levels within the Paleocene mudrocks,spanning from immature to marginally mature,with increasing maturity observed with greater *** comparison,the organic composition and depositional environments of Paleocene source rocks in the Tano Basin closely resemble those found in the Niger delta Basin,Douala,and Kribi-Campo Basins,the Kwanza Formation in Angola,and certain Brazilian marginal ***,it is worth noting that Paleocene source rocks in some of the basins,such as the Niger delta and Brazilian marginal basins,exhibit rela-tively higher thermal maturity levels compared to those observed in the current Paleocene samp

关键词： Paleocene source rocks Source input depositional environment Thermal maturity Hydrocarbon potential Tano Basin West Africa

Autophagy, apoptosis and organelle features during cell exposure to cadmiumč

在线全文

学校读者我要写书评

暂无评论

BIOCELL 2013年第2期37卷 45-54页

作者： CRISTIANE DOS SANTOS VERGILIO edÉSIO JOSÉTENÓRIO de MELO Universidade Estadual do Norte Fluminense Centro de Biociências e BiotecnologiaLaboratório de Biologia Celular e TecidualCampos dos GoytacazesRJBrasil28013-602.

Cadmium(Cd)induces several effects in different tissues,but our knowledge of the toxic effects on organelles is insuffi *** observe the progression of Cd effects on organelle structure and function,HuH-7 cells(human hepatic carcinoma cell line)were exposed to CdCl2 in increasing concentrations(1μM–20μM)and exposure times(2 h–24 h).During Cd treatment,the cells exhibited a progressive decrease in viability that was both time-and *** treated cells displayed progressive morphological changes that included cytoplasm retraction and nuclear condensation preceding a total loss of cell *** with 10μM for 12 h led to irreversible *** these drastic and irreparable damages,treated cells(5μM for 12 h)presented a progressive loss of mitochondrial function and cytoplasm acidifi cation as well as dysfunction and disorganization of microfi laments and endoplasmic *** damages led to the induction of apoptotic events and an increase in autophagic bodies in the *** results revealed that Cd affects multiple intra-cellular targets that induce alterations in the mitochondria,cytoskeleton,endoplasmic reticulum and acidic compartments,ultimately culminating in cell death via apoptotic and autophagic pathways.

关键词： Cd cell death hepatocyte HuH-7 cells mitochondria

Fritz Ackermann:a true and unequalled friend

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geo-Spatial Information Science 2023年第2期26卷 151-152页

作者： ed Mikhail Professor Emeritus&Former Head Geomatics Engineering Purdue UniversityWest LafayetteINUSA

I am certain that several other contributors to this memorial volume have expounded on the many attributes,both professional and personal,of Professor Fritz *** is unquestionable that he was a giant in our field,on whose shoulders current and future practitioners shall stand in order to keep the wheels of progress and advancement moving forward.

关键词： moving Fritz Ackermann

Fragmentation of fuel pellets during transport via a belt conveyor:A design of experiment study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2022年第7期20卷 29-37页

作者： Hamid Gilvari Coen H.H.van Battum Richard Farnish Yusong Pang Wiebren de jong Dingena L.Schott Section of Transport Engineering and Logistics Department of Maritime&Transport TechnologyFaculty of MechanicalMaritime and Materials EngineeringDelft University of TechnologyThe Netherlands Wolfson Centre for Bulk Solids Handling Technology Faculty of Engineering&ScienceUniversity of GreenwichUnited Kingdom Section of Large Scale Energy Storage(LSE) Department of Process&EnergyFaculty of MechanicalMaritime and Materials EngineeringDelft University of TechnologyThe Netherlands

This work investigates the proportion of generated fines in a pilot-scale experiment using a belt conveyor and commercial fuel *** this,a belt conveyor with a length of 3.1 m was used and operated at varying conditions:speeds,percentages of material loading on the belt,two combinations of the inclination angle of the belt and the falling height,and a different number of handling *** considered a design of experiments approach based on response surface methodology to investigate the effect of different conditions on the potential of fines ***,a comparison between the results of the belt conveyor and three common benchmark experimental approaches(tumbling box,rotary impact tester,and mechanical compression test)was *** show that the number of handling steps and the combined effect of drop height and inclination angle directly affected the fines ***,the tested belt speed range and the level of loading were of lower significance.A polynomial quadratic model was derived based on the regression analysis and showed a high accuracy to predict the proportion of ***,the tumbling box method showed good potential to predict the proportion of fines in a belt conveyor when transported several times.

关键词： Fuel pellets Breakage Belt conveyor Transport design of experiment Box–Behnken design