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国际医学放射学杂志 2021年第5期 604-605页

作者： N.Y.Shin M.Bang S.W.yoo j.S.Kim e.Yun Ui.yoon 宋瑞瑞

摘要组间比较结果显示皮质变薄与帕金森病(PD)痴呆(PDD)相关联,但其在临床上的应用受限。目的基于机器学习的模型,研究MRI影像上皮质厚度是否有助于在个体水

关键词：

Measurements of dihadron correlations relative to the event plane in Au+Au collisions at√^(S)NN=200 GeV

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Chinese Physics C 2021年第4期45卷 198-241页

作者： H.Agakishiev M.M.Aggarwal Z.Ahammed A.V.Alakhverdyants I.Alekseev j.Alford B.D.Anderson C.D.Anson D.Arkhipkin G.S.Averichev j.Balewski D.R.Beavis N.K.Behera R.Bellwied M.j.Betancourt R.R.Betts A.Bhasin A.K.Bhat H.Bichsel j.Bieleik j.Bielcikova B.Biritz L.C.Bland W.Borowski j.Bouchet e.Braidot A.V.Brandin A.Bridgeman S.G.Brovko e.Bruna S.Bueltmann I.Bunzarov T.P.Burton X.Z.Cai H.Caines M.Calderon de la Barca Sanchez D.Cebra R.Cendejas M.C.Cervantes Z.Chajecki P.Chaloupka S.Chattopadhyay H.F.Chen j.H.Chen j.Y.Chen L.Chen j.Cheng M.Cherney A.Chikanian K.e.Choi W.Christie P.Chung M.j.M.Codrington R.Corliss j.G.Cramer H.j.Crawford S.Dash A.Davila Leyva L.C.De Silvat R.R.Debbe T.G.Dedovich A.A.Derevschikov R.Derradi de Souza L.Didenko P.Djawotho S.M.Dogra X.Dong j.L.Drachenberg j.e.Draper j.C.Dunlop L.G efimov M.elnim j.engelage G eppley M.estienne L.eun O.evdokimov R.Fatemi j.Fedorisin A.Feng R.G.Fersch P.Filip e.Finch V.Fine Y.Fisyak C.A.Gagliardi D.R.Gangadharan A.Geromitsos F.Geurts P.Ghosh Y.N.Gorbunov A.Gordon O.Grebenyuk D.Grosnick S.M.Guertin A.Gupta W.Guryn B.Haag O.Hajkova A.Hamed L-X.Han j.W.Harris j.P.Hays-Wehle M.Heinz S.Heppelmann A.Hirsch e.Hjort G.W.Hoffmann D.j.Hofiman B.Huang H.Z.Huang T.j.Humanic L.Huo G.Igo P.jacobs W.W.jacobs C.jena F.jin j.joseph e.G.judd S.Kabana K.Kang j.Kapitan K.Kauder H.Ke D.Keane A.Kechechyan D.Kettler D.P.Kikola j.Kiryluk A.Kisiel V.Kizka A.G.Knospe D.D.Koetke T.Kollegger j.Konzer I.Koralt L.Koroleva W.Korsch L.Kotchenda V.Kouchpil P.Kravtsov K.Krueger M.Krus L.Kumar P.Kurnadi M.A.C.Lamont j.M.Landgraf S.LaPointe j.Lauret A.Lebedev R.Lednicky j.H.Lee W.Leight M.j.LeVine C.Lil L.Li N.Li W.Li X.Li X.Li Y.Li Z.M.Li M.A.Lisa F.Liu H.Liu j.Liu T.Ljubicic W.j.Llope R.S.Longacre W.A.Love Y.Lu e.V.Lukashov X.Luo G.L.Ma Y.G.Mai D.P.Mahapatra R.Majka O.I.Mall L.K.Mangotra R.Manweiler S.Margetis C.Markert H.Masui H.S.Matis Yu.A.Matulenko D.MeDonald T.S.McShane A.Meschanin R.Milner N.G.Minaev S.Mioduszewski A.Mischke M.K.Mitrovski B.Mohanty M.M.Mondal B.Morozov D.A.Morozov M.G.Munhoz M Argonne National Laboratory Argonnellinois 60439USA Brookhaven National Laboratory UptonNew York 11973USA University of Califomia BerkeleyCaliformnia 94720USA University of California DavisCalifornia 95616USA University of Califormnia Los AngelesCalifomia 90095USA Universidade estadual de Campinas Sao PauloBrazil University of Illinois at Chicago ChicagoIlinois 60607USA Creighton University OmahaNebraska 68178USA Czech Technical University in Prague FNSPEPrague11519Czech Republic Nuclear Physics Institute AS CR 25068 Rez/PragueCzech Republic University of Frankfurt FrankfurtGermany Institute of Physics Bhubaneswar 751005India Indian Institute of Technology MumbaiIndia Indiana University BloomingtonIndiana 47408USA Alikhanov Instiute for Theoretical and experimental Physics MoscowRussia University of jammu Jammu 180001India joint Institute for Nuclear Research Dubna141980Russia Kent State University KentOhio 44242USA University of Kentucky LexingtonKentucky40506-0055USA Institute of Modern Physics LanzhouChina Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720USA Massachusetts Institute of Technology CambridgeMA 02139-4307USA Mx-Planck-Institut fir Physik MunichGermany Michigan State University East LansingMichigan 48824USA Moscow engineering Physics Institute Moscow Russia NIKHeF and Utrecht University AmsterdamThe Netherlands Ohio State University ColumbusOhio 43210USA Old Dominion University NorfolkVA23529USA Panjab University Chandigarh 160014India PennsyIvania State University University ParkPennsylvania 16802USA Institute of High energy Physics ProtvinoRussia Purdue University West LafayetteIndiana 47907USA Pusan National University PusanRepublic of Korea University of Rajasthan Jaipur 302004India Rice University HoustonTexas 77251USA Universidade de Sao Paulo Sao PauloBrazil University of Science&Technology of China Hefei 230026.China Shandong University JinanShandong 250100China Shanghai Institute of Applied Physics Shanghai 201800Chi

Dihadron azimuthal correlations containing a high transverse momentum(pr)trigger particle are sensit-ive to the properties of the nuclear medium created at RHIC through the strong interactions occurring between the traversing parton and the medium,*** measurements revealed a strong modification to di-hadron azimuthal correlations in Au+Au collisions with respect to ptp and d+Au *** modification in-creases with the collision centrality,suggesting a path-length or energy density dependence to the je-quenching *** paper reports STAR measurements of dihadron azimuthal correlations in mid-central(20%-60%)Au+Au collisions at√^(S)NN=200 GeV as a function of the trigger particle's azimuthal angle relative to the event plane,Ф_(s)=|Ф_(t)-ψ_(ep)|.The azimuthal correlation is studied as a function of both the trigger and associated particle *** subtractions of the combinatorial background and anisotropic flow,assuming Zero Yield At Minimum(ZYAM),are *** correlation results are first discussed with subtraction of the even harmonic(elliptic and quadrangu-lar)flow *** away-side correlation is strongly modifed,and the modification varies withФ_(s),with a double-peak structure for out-of-plane trigger *** near-side ridge(long range pseudo-rapidity△_(η)correla-tion)appears to drop with increasingФ_(s)while the jet-like component remains approximately *** correla-tion functions are further studied with the subtraction of odd harmonic triangular flow background arising from *** is found that the triangular flow,while responsible for the majority of the amplitudes,is not sufficient to explain theφs-dependence of the ridge or the away-side double-peak *** dropping ridge withФ_(s)could be attributed to aФ_(s)-dependent lliptie anisotropy;however,the physics mechanism of the ridge remains an open *** with aФ_(s)-dependent elliptic flow,the away-side correlation structure

关键词： relativistic heavy ion collisions dihadron correlations jet-medium interactions anisotropic flow background event plane

Pharmacological characterizationof synthetic cannabinoid MAM-2201：radioligand binding and abuse-related effects

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中国药理学与毒理学杂志 2017年第10期31卷 1016-1017页

作者： William e FANTeGROSSI Aaron jANOWSKY Amy j eSHLeMAN Lauren N RUSSeLL Saki FUKUDA jyoti GOGOI Cassandra PRIOLeAU Ambuja S BALe Srihari R TeLLA Merle G PAULe Takato HIRANITA Department of Pharmacology and Toxicology College of Medicine University of Arkansas for Medical Sciences AR 72207 Division of Neurotoxicology National Center for Toxicological Research Food and Drug Administration AR 72079 Departments of Psychiatry and Behavioral Neuroscience Oregon Health & Science University Portland OR 97239-3098 VA Portland Health Care System Portland OR 97239 Drug and Chemical evaluation Section Drug Enforcement Administration

OBjeCTIVe Over 30% of all new psychoactive substances identified by the UN Office on Drugs and Crime in 2016 were synthetic *** recent emergence of MAM-2201 on the illicit market is troubling because this drug has no precedent in either the scientific or patent literature,and appears to be a novel compound developed specifically as a "graymarket" drug of abuse bystructurally combining the known synthetic cannabinoids jWH-122 and *** is currently no published information regarding the pharmacology of *** The present studies characterized cannabinoid-like effects of MAM-2201 in vitro(interactions with cannabinoid type 1 receptors[CB1 Rs]) and in vivo(in mice and rats).ReSULTS In a radioligand binding assay using [3 H]CP55,940 in HeK cell membranes transfected with the CB1 R,MAM-2201(K i=5.4 nmol·L^(-1)),had higher binding affinity than win 55,212-2(K i=80 nmol·L^(-1)),and D9-THC(K i=8.3 nmol·L^(-1)).The e max values for MAM-2201 and win 55,212-2 in an assay of agonist inhibition of forskolin-stimulated c AMP were 85%(eC50=0.45 nmol·L^(-1)) and 95%,respectively,as compared with the D9-THC e max of 74%.In mice,MAM-2201(0.003-1.0 mg·kg^(-1),IP) produced dose-dependent cannabimimetic effects which were both more potent and more effective than those of ***-2201 and D9-THC dose-dependently produced hypothermia:eD50=0.287 and 25.4 mg·kg^(-1),analgesia:eD50=0.125 and 29.4 mg·kg^(-1),and catalepsy:eD50=0.301 and18.9 mg·kg^(-1) in adult male CD1 ***,MAM-2201 also elicited convulsant effects at a dose of 1.0 mg·kg^(-1) in 8/8 murine *** rats,MAM-2201 produced dose-dependent D9-THC-like interoceptive effects in subjects trained to discriminate 3.0 mg·kg^(-1)(IP) D9-THC from *** MAM-2201 binds CB1 Rs with high affinity and agonist efficacy,and functions as a potent cannabinoid agonist in vivo across several complementary measures of cannabinoid activity in two rodent species.

关键词： cannabinoid CB1 receptor behavior abuse liability

术前动态对比增强MRI预测γ刀治疗前庭神经鞘瘤治疗反应的前瞻性研究

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国际医学放射学杂志 2022年第4期 492-492页

作者： I.Hwang S.H.Choi j.W.Kim e.K.Yeon j.Y.Lee R.e.yoo 张晓涵

摘要目的目前对前庭神经鞘瘤（VS）γ刀放疗（GKRS）治疗反应的预测因素了解甚少。本研究探讨γ刀治疗前的动态增强（DCe）-MRI指标预测散发性VS治疗反应的价值。方

关键词：

对比增强MRI T1映射用于定量评估睡眠-觉醒状态下人脑中假定的动态胶质淋巴活动

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国际医学放射学杂志 2021年第6期 732-732页

作者： S.Lee R.e.yoo S.H.Choi S.H.Oh S.ji j.Lee 何博

鞘内注射对比剂对淋巴系统的评估在临床上应用有限。目的探讨使用连续静脉内对比增强T1映射定量评估不同脑区假定的动态胶质淋巴活动的可行性,并证明睡眠对

关键词：

薄层双反转恢复MRI上Brodmann 4区三层结构的表现

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国际医学放射学杂志 2009年第2期32卷 190-190页

作者： e.Y.Kim D.H.Kim e.yoo j.W.Lee H.j.Park 高欣 Department of Radiology Research Institute of Radiological ScienceYonsei University College of Medicine

目的探讨3．0T的薄层轴向双反转恢复（DIR）MRI能否根据“三层结构”的显示与否区分初级运动皮质（PMC或Brodmann 4区）与其他所选皮质区域包括初级感觉皮质（PSC或Brodmann 1-3区）。方法该前瞻性研究获机构审查委员会批准和病人... 详细信息

目的探讨3．0T的薄层轴向双反转恢复（DIR）MRI能否根据“三层结构”的显示与否区分初级运动皮质（PMC或Brodmann 4区）与其他所选皮质区域包括初级感觉皮质（PSC或Brodmann 1-3区）。方法该前瞻性研究获机构审查委员会批准和病人知情同意。研究包括3．0T MRI表现正常的191例病人（女94例，年龄5～80岁；男97例，年龄5～76岁）。

关键词： MRI表现反转恢复三层结构薄层初级运动皮质感觉皮质病人知情皮质区

High temperature co-firing of 3D-printed AleZnO/Al_(2)O_(3) multimaterial two-phase flow sensor

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journal of Materiomics 2022年第3期8卷 710-718页

作者： Danwei Zhang win jonhson Tun Seng Herng Xi Xu Xiaojing Liu Liang-ming Pan Hui He jun Ding Department of Materials Science and engineering Faculty of EngineeringNational University of Singapore9 Engineering Drive 1117576Singapore Institute of Materials Research and engineering Agency for ScienceTechnology and Research2 Fusionopolis Way138635Singapore Institute of Flexible electronics Xi'an Key Laboratory of Flexible ElectronicsNorthwestern Polytechnical UniversityXi'an710072China School of Nuclear Science and engineering Shanghai Jiao Tong UniversityShanghai200240China Key Laboratory of Low-Grade energy Utilization Technologies and Systems(Chongqing University) Ministry of EducationChongqing400044China

Sensors are crucial in the understanding of machines working under high temperatures and highpressure *** devices utilize polymeric materials as electrical insulators which pose a challenge in the device's ***,on the other hand,is robust and able to withstand high temperature and *** such applications,a co-fired ceramic device which can provide both electrical conductivity and insulation is beneficial and acts as a superior candidate for sensor *** this paper,we propose a novel fabrication technique of complex multi-ceramics structures via 3D *** fabrication methodology increases both the geometrical complexity and the device's shape *** ceramics(alumina)was employed as the electrical insulator whilst providing mechanical rigidity while a functional ceramic(alumina-doped zinc oxide)was employed as the electrically conductive *** addition of sintering additives,tailoring the printing pastes'solid loadings and heat treatment profile resolves multi-materials printing challenges such as shrinkage disparity and densification *** high-temperature co-firing of ceramics(HTCC)technology,dense high quality functional multi-ceramics structures are *** proposed fabrication methodology paves the way for multi-ceramics sensors to be utilized in high temperature and pressure systems in the near future.

关键词： 3D printing Multi-material Robocasting Sensors Ceramics

Redesigning crop varieties to win the race between climate change and food security

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Molecular Plant 2023年第10期16卷 1590-1611页

作者： Kevin V.Pixley jill e.Cairns Santiago Lopez-Ridaura Chris O.Ojiewo Maryam Abba Dawud Inoussa Drabo Taye Mindaye Baloua Nebie Godfrey Asea Biswanath Das Happy Daudi Haile Desmae Benoit joseph Batieno Ousmane Boukar Clare T.M.Mukankusi Stanley T.Nkalubo Sarah j.Hearne Kanwarpal S.Dhugga Harish Gandhi Sieglinde Snapp ernesto Adair Zepeda-Villarreal International Maize and Wheat Improvement Center(CIMMYT) TexcocoMexico International Maize and Wheat Improvement Center(CIMMYT) HarareZimbabwe International Maize and Wheat Improvement Center(CIMMYT) NairobiKenya Lake Chad Research Institute(LCRI) MaidiguriNigeria International Maize and Wheat Improvement Center(CIMMYT) DakarSenegal ethiopian Institute of Agricultural Research(eIAR) Addis AbabaEthiopia National Agricultural Research Organization(NARO) KampalaUganda Tanzania Agricultural Research Institute(TARI) NaliendeleTanzania Institut de l'environnement et de Recherches Agricoles(INeRA) OuagadougouBurkina Faso International Institute of Tropicl Agriculture(IITA) KanoNigeria Alliance of Bioversity International and CIAT KampalaUganda

Climate change poses daunting challenges to agricultural production and food *** temperatures,shifting weather patterns,and more frequent extreme events have already demonstrated their effects on local,regional,and global agricultural *** varieties that withstand climate-related stresses and are suitable for cultivation in innovative cropping systems will be crucial to maximize risk avoidance,productivity,and profitability under climate-changed *** surveyed 588 expert stakeholders to predict current and novel traits that may be essential for future pearl millet,sorghum,maize,groundnut,cowpea,and common bean varieties,particularly in sub-Saharan *** then review the current progress and prospects for breeding three prioritized future-essential traits for each of these *** predict that most current breeding priorities will remain important,but that rates of genetic gain must increase to keep pace with climate challenges and consumer ***,the predicted future-essential traits include innovative breeding targets that must also be prioritized;for example,(1)optimized rhizosphere microbiome,with benefits for P,N,and water use efficiency,(2)optimized performance across or in specific cropping systems,(3)lower nighttime respiration,(4)improved stover quality,and(5)increased early *** further discuss cutting-edge tools and approaches to discover,validate,and incorporate novel genetic diversity from exotic germplasm into breeding populations with unprecedented precision,accuracy,and *** conclude that the greatest challenge to developing crop varieties to win the race between climate change and food security might be our innovativeness in defining and boldness to breed for the traits of tomorrow.

关键词： climate change food security crop breeding cropping systems expert survey sub-Saharan Africa

非牛顿流体在圆管湍流流动中管径对传热及摩擦系数的影响

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油气储运 1980年第2期 79-85页

作者： j.P.哈耐特 K.S.恩哥 j.e.栾生江体乾徐英农上海化工学院

本文对 Carbopol 溶液和 Attagel 的水溶液,在流经内径为2.21厘米和1.30厘米的圆管作湍流流动时的传热和压降,获得了实验结果。供实验的溶液是纯粘性非牛顿流体,其流动特性指数在0.4～1.0之间变化。发现管径对无因次热传递以及摩擦因子... 详细信息

本文对 Carbopol 溶液和 Attagel 的水溶液,在流经内径为2.21厘米和1.30厘米的圆管作湍流流动时的传热和压降,获得了实验结果。供实验的溶液是纯粘性非牛顿流体,其流动特性指数在0.4～1.0之间变化。发现管径对无因次热传递以及摩擦因子无影响,压强降数据与 Dotge 和Metzner 的预测值非常吻合,同时所测得的热传递数据与 yoo 和 Hartnett 的关联式非常一致。对于纯粘性非牛顿流体,其流体动力学和热进口段的长度和牛顿流体的量级相同。

关键词：雷诺数预测值实验值 ReYNOLDS数湍流流动紊流流动粘性流动热传递流动特性指数管径圆管金属管关联式流体动力学圆管流动摩擦系数

Attribution of PM_(2.5) exposure in Beijing-Tianjin-Hebei region to emissions:implication to control strategies

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Science Bulletin 2017年第13期62卷 957-964页

作者： Xin Li Qiang Zhang Yang Zhang Lin Zhang Yuxuan Wang Qianqian Zhang Meng Li Yixuan Zheng Guannan Geng Timothy j.Wallington Weijian Han Wei Shen Kebin He Ministry of education Key Laboratory for earth System Modeling Department of Earth System ScienceTsinghua University Department of Marine Earthand Atmospheric SciencesNorth Carolina State University Collaborative Innovation Center for Regional environmental Quality Laboratory for Climate and Ocean-Atmosphere Sciences Department of Atmospheric and Oceanic SciencesSchool of PhysicsPeking University Department of Marine Sciences Texas A&M University at Galveston Department of Atmospheric Sciences Texas A&M UniversityCollege Station National Satellite Meteorological Center China Meteorological Administration Research and Advanced engineering Ford Motor Company Asia Pacific Research Ford Motor Company State Key joint Laboratory of environment Simulation and Pollution Control School of EnvironmentTsinghua University

The Beijing-Tianjin-Hebei （BTH） region is one of the most heavily polluted regions in China, with both high PM2.5 concentrations and a high population density. A quantitative source-receptor relationship can provide valuable insights that can inform effective emission control strategies. Both source appor- tionment （SA） and source sensitivity （SS） can provide such information from different perspectives. In this study, both methods are applied in northern China to identify the most significant emission cate- gories and source regions for PMz5 exposure in BTH in 2013. Despite their differences, both models show similar distribution patterns for population and simulated PM2.5 concentrations, resulting in overall high PM2.5 exposure values （approximately 110 Ixg/m3） and particularly high exposure values during the.win- ter （approximately 200 ktg/m3）. Both methods show that local emissions play a dominant role （70%）, with some contribution from surrounding provinces （e.g., Shandong） via regional transport. The two methods also agree on the priority of local emission controls： both identify industrial, residential, and agricultural emissions as the top three categories that should be controlled locally. In addition, the effect of control- ling agricultural ammonia emissions is approximately doubled when the co-benefits of reducing nitrate are considered. The synthesis of SA and SS for addressing specific categories of emissions provides a quantitative basis for the development of emission control strategies and policies for controlling PM2.5 in China.

关键词： PM2.5 exposureSource apportionmentSource sensitivityControl priorityChina