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Optimization of Cooperative RelayingMolecular Communications for Nanomedical Applications

Computer Modeling in engineering & sciences 2024年第2期138卷 1259-1275页

作者： e.an s.attia Ashraf A.M.Khalaf Fathi e.Abd el-samie saied M.Abd el-atty Konstantinos A.Lizos Osama Alfarraj Heba M.el-Hoseny Department of electrical engineering Faculty of EngineeringMinia UniversityMinia61111Egypt Department of electronics and electrical Communications engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Department of Informatics Faculty of Mathematics and Natural SciencesUniversity of Oslo(UiO)OsloNorway Computer science Department Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Department of Computer science The Higher Future Institute for Specialized Technological StudiesEl ShoroukEgypt

Recently,nano-systems based on molecular communications via diffusion(MCvD)have been implemented in a variety of nanomedical applications,most notably in targeted drug delivery system(TDDs)***,because the MCvD is unreliable.and there exists molecular noise.and inter symbol interference(IsI),cooperative nano-relays can acquire the reliability for drug delivery to targeted diseased cells,especially if the separation distance between the nano transmitter and nano receiver is *** this work,we propose.an approach for optimizing the performance of the nano system using cooperative molecular communications with a nano relay scheme,while accounting for blood flow effects in terms of drift *** fractions of the molecular drug that should be allocated to the nano transmitter and nano relay positioning are computed using a collaborative optimization problem solved by theModified Central Force Optimization(MCFO)*** the previous work,the probability of bit error is expressed in a closed-form *** is used as an objective function to determine the optimal velocity of the drug molecules and the detection threshold at the nano *** simulation results show that the probability of bit error can be dramatically reduced by optimizing the drift velocity,detection threshold,location of the nano-relay in the proposed nano system,and molecular drug budget.

关键词： Nanomedical system molecular communication cooperative relay optimization

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Climate change induced heat stress impact on workplace productivity in a net zero-carbon timber building towards the end of the century

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Building simulation 2024年第6期17卷 893-906页

作者： Deepak Amaripadath Mattheos santamouris shady attia school of Geographical sciences and Urban Planning Arizona State UniversityTempeAZUSA Urban Climate Research Center Arizona State UniversityTempeAZUSA school of Built environment University of New South Wales2052SydneyAustralia sustainable Building Design Lab Department of UEEFaculty of Applied SciencesUniversity of Liege4000LiegeBelgium

Changing climate intensifies heat stress,resulting in a greater risk of workplace productivity decline in timber office buildings with low internal thermal *** impact of climate change induced heat exposure on indoor workplace productivity in timber office buildings has not been extensively ***,further investigation to reduce the work capacity decline towards the end of the century is ***,heat exposure in a net zero-carbon timber building near Brussels,Belgium,was evaluated using a reproducible comparative approach with different internal thermal mass *** analysis indicated that strategies with increased thermal mass were more effective in limiting the effects of heat exposure on workplace *** medium and high thermal mass strategies reduced workplace productivity loss to 0.1%in the current,0.3%and 0.2%in the midfuture.and 4.9%and 3.9%for future *** comparison,baseline with low thermal mass yielded a decline of 2.3%,3.3%,and 8.2%.The variation in maximum and minimum wet-bulb globe temperatures were also lower for medium and high thermal mass strategies than for low thermal mass *** study findings lead to the formulation of design guidelines,identification of research gaps,and recommendations for future work.

关键词： heat exposure office buildings work capacity thermal mass climate change

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Mitigating diabetes-related complications:empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats

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World Journal of Diabetes 2024年第8期15卷 1778-1792页

作者： Mai s.attia Fadwa Ayman Mohamed s.attia Galal Yahya Mansour H Zahra Magdi Mohamed Ibrahim Khalil Abdel Aziz A Diab Department of Zoology Faculty of ScienceZagazig 44519Egypt Department of Pharmaceutics Faculty of PharmacyZagazig 44519Egypt Department of Microbiology and Immunology Faculty of PharmacyZagazig UniversityZagazig 44519Egypt Department of Biochemistry Faculty of MedicineZagazig 44519Egypt

BACKGROUND Type 2 diabetes is one of the most prevalent chronic diseases worldwide,significantly impacting patients'quality of *** treatment options like metformin(MeT)effectively counteract hyperglycemia but fail to alleviate diabetes-associated complications such as retinopathy,neuropathy,nephropathy,hepatopathy,and cardiovascular *** To propose the supplementation of cholecalciferol(CHO)and taurine(TAU)to enhance MeT efficacy in controlling diabetes while minimizing the risk of associated *** The study involved sixty rats,including ten non-diabetic control rats and fifty experimental rats with type 2 diabetes induced by *** experimental rats were further subdivided into positive control and treatment *** four treatment groups were randomly allocated to a single MeT treatment or MeT combined with supplements either CHO,TAU,or *** Diabetic rats exhibited elevated levels of glucose,insulin,Homeostasis Model Assessment of Insulin Resistance(HOMA-IR),glycated hemoglobin percentage,lipid markers,aspartate aminotransferase.and malondialdehyde,along with reduced levels of antioxidant enzymes(catalase.and superoxide dismutase).The administration of CHO and TAU supplements alongside MeT in diabetic rats led to a noticeable recovery of islet *** antioxidative.anti-inflammatory,and anti-apoptotic properties of the proposed combination therapy significantly ameliorated the aforementioned *** The supplementation of CHO and TAU with MeT showed the potential to significantly improve metabolic parameters and protect against diabetic complications through its antioxidative.anti-inflammatory,and antiapoptotic effects.

关键词： Diabetes complications Metformin Cholecalciferol Taurine Glycated hemoglobin% Antioxidant

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Insulin therapy in type 2 diabetes: Insights into clinical efficacy, patient-reported outcomes, and adherence challenges

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World Journal of Diabetes 2024年第5期15卷 828-852页

作者： Mahmoud emad-eldin Ge.an F Balata e.an A elshorbagy Mona s Hamed Mohamed s.attia Department of Pharmacy Practice Faculty of PharmacyZagazig UniversityZagazig HFQM+872Al-Sharqia GovernorateEgypt Department of Pharmacy Practice Faculty of PharmacyHeliopolis UniversityCairo 44519Egypt Department of Pharmaceutics Faculty of PharmacyZagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt Department of Internal Medicine Faculty of MedicineZagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt Department of Community at Faculty of Medicine Zagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt

Insulin therapy plays a crucial role in the management of type 2 diabetes as the disease *** the past century,insulin formulations have undergone significant modifications and bioengineering,resulting in a diverse range of available insulin *** products show distinct pharmacokinetic and pharmacodynamic ***,various insulin regimens have em-erged for the management of type 2 diabetes,including premixed formulations and combinations of basal and bolus *** utilization of different insulin regimens yields disparate clinical outcomes,adverse events,and,notably,patient-reported outcomes(PROs).PROs provide valuable insights from the patient’s perspective,serving as a valuable mine of information for enhancing healthcare.and informing clinical *** to insulin therapy,a critical patient-reported outcome,significantly affects clinical outcomes and is influenced by multiple *** review provides insights into the clinical effectiveness of various insulin preparations,PROs,and factors impacting insulin therapy adherence,with the aim of enhancing healthcare practices and informing clinical decisions for individuals with type 2 diabetes.

关键词： Adherence Diabetes Insulin Patient-reported outcomes Pharmacokinetic Pharmacodynamic

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Common coupled fixed point theorem for two pairs compatible.and sub-sequentially continuous mapping

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Journal of Ocean engineering and science 2024年第4期9卷 401-407页

作者： H.M.Abu-Donia Mona s.Bakry H.A.Atia Omnia M.A.Khater Raghda A.M.attia Department of Mathematics Faculty of ScienceZagazig UniversityZagazigEgypt Department of Mathematics Faculty of ScienceTanta UniversityTantaEgypt Department of Basic science Zagazig Higher Institute of Engineering and TechnologyZagazigEgypt Department of Basic science Higher Technological Institute 10th of Ramadan CityEl Sharqia 44634Egypt

This study establishes a common coupled fixed point for two pairs of compatible.and sequentially continuous mappings in the intuitionistic fuzzy metric space that satisfy theφ-contractive *** basic definitions and theorems have been used from some recent scientific papers about the binary operator,t-norm,t-conorm,intuitionistic fuzzy metric space.and compatible mapping for reaching to the paper’s purpose.

关键词： Intuitionistic fuzzy metric space φ-contractive mapping Compatible mappings Couple fixed point

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seed Priming with Potassium Nitrate Can enhance salt stress Tole.ance in Maize

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Phyton-International Journal of experimental Botany 2024年第8期93卷 1819-1838页

作者： Bushra Rehman Asma Zulfiqar Houneida attia Re.ana sardar Muneera A.saleh Khalid H.Alamer Ibtisam M.Alsudays Faisal Mehmood Qamar uz Zaman Institute of Botany University of the PunjabLahore54590Pakistan Department of Biology College of ScienceTaif UniversityTaif21944Saudi Arabia Department of Botany Emerson UniversityMultan60000Pakistan Biological sciences Department Faculty of Science and ArtsKing Abdulaziz UniversityRabigh21911Saudi Arabia Department of Biology College of ScienceQassim UniversityBurydah52571Saudi Arabia Department of Chemistry sciences The University of LahoreLahore54590Pakistan Department of environmental sciences The University of LahoreLahore54590Pakistan

salinity is a major abiotic stress that hinders plant development and productivity and influences agricultural *** priming is a technique used to boost germination and seedling growth under abiotic stress.A pot experiment was conducted to evaluate the impact of seed priming with potassium nitrate(KNO_(3))at various levels(0%,0.50%,1.00%and 1.50%)under salt stress(0,75,100 mM NaCl)on two maize verities(MNH360 and 30T60)for the growth,development and metabolic attributes results revealed that in maize variety MNH360,KNO_(3)priming’s significantly enhanced growth parameters than in maize variety 30T60 under control and salt-stressed *** with KNO_(3)enhanced carotenoids and total chlorophyll in the 30T60 variety that protected the maize plants from salt ***,it was shown that priming with 1.00%KNO_(3)acts as safeguarded to protect them from oxidative damage by salt stress minimizing reactive oxygen species(ROs)formation through increased levels of malondialdehyde(MDA),catalase(CAT),peroxidase(POD),ascorbate peroxidase(APX),and total soluble *** findings of the present study confirm that the use of the KNO_(3)seed priming technique is a lowcost,environmentally friendly technique for mitigating adverse impacts of salt stress in maize crops by activating the.antioxidant defense system and improving chlorophyll and osmolyte contents.

关键词： salinity Zea mays antioxidant enzymes growth seedlings oxidative damage

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embedded Coded Relay system for Molecular Communications

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Computers, Materials & Continua 2022年第8期72卷 2729-2748页

作者： e.an s.attia Ashraf A.M.Khalaf Fathi e.Abd el-samie saied M.Abd el-atty Konstantinos A.Lizos Osama Alfarraj Farid shawki Imran Khan Ki-Il Kim Department of electrical engineering Faculty of EngineeringMinia UniversityMiniaEgypt Department of electronics and electrical Communications Faculty of Electronic EngineeringMenoufia UniversityMenoufiaEgypt Department of Informatics Faculty of Mathematics and Natural SciencesUniversity of Oslo(UiO)Norway Computer science Department Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Department of electrical engineering University of Engineering&TechnologyPeshawar814Pakistan Department of Computer science.and engineering Chungnam National UniversityDaejeon34134Korea

With the emergence of the COVID-19 pandemic,the World Health Organization(WHO)has urged scientists and industrialists to exploremodern information and communication technology(ICT)as a means to reduce or even eliminate *** World Health Organization recently reported that the virus may infect the organism through any organ in the living body,such as the respiratory,the immunity,the nervous,the digestive,or the cardiovascular *** the abovementioned goal,we envision an implanted nanosystem embedded in the intra living-body *** main function of the nanosystem is either to perform diagnosis and mitigation of infectious diseases or to implement a targeted drug delivery system(i.e.,delivery of the therapeutic drug to the diseased tissue or targeted cell).The communication among the nanomachines is accomplished via communication-based molecular *** control/interconnection of the nanosystem is accomplished through the utilization of Internet of bio-nano things(IoBNT).The proposed nanosystem is designed to employ a coded relay nanomachine disciplined by the decode.and forward(DF)principle to ensure reliable drug delivery to the targeted ***,both the sensitivity of the drug dose.and the phenomenon of drug molecules loss before delivery to the target cell site in long-distance due to the molecules diffusion process are taken into *** this paper,a coded relay NM with conventional coding techniques such as Rs and Turbo codes is selected to achieve minimum bit error rate(BeR)performance.and high signal-to-noise ratio(sNR),while the detection process is based on maximum likelihood(ML)probability and minimum error probability(MeP).The performance.analysis of the proposed scheme is evaluated in terms of channel capacity and bit error rate by varying system parameters such as relay position,number of released molecules,relay and receiver *** results are validated through simulation and demonstrate that the proposed scheme can

关键词： Molecular communication nanonetwork internet of bio-nano things coded relay scheme coding

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Review on sol-Gel Derived Coatings: Process, Techniques and Optical Applications

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Journal of Materials science & Technology 2002年第3期18卷 211-218页

作者： s.M.attia Jue.anG 等 PohlInstituteofsolidstatePhysics TongjiUniversityShanghai200092China Phys.Dept.Facultyofeducation KaferEl-SheikhEgypt

sol-gel process is one of the simplest techniques to manufacture thin films. The quality of the prepared films depends on the parameters of the sol-gel process and the used technique for deposition. A great variety of the sol-gel derived films have been prepared for different applications. We present a review on the sol-gel derived coatings. The description of the process is introduced in details. Different sol-gel deposition techniques are mentioned. The optical applications of the sol-gel derived coatings are reviewed.

关键词： sol-gel process Coating Thin film

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Fermentation, formulation and evaluation of PGPR Bacillus subtilis isolate as a bioagent for reducing occurrence of peanut soil-borne diseases

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Journal of Integrative Agriculture 2019年第9期18卷 2080-2092页

作者： Abdel-Gayed M.Ahmad Abo-Zaid G.attia Matar s.Mohamed Hafez e.elsayed Onion Garlic and Oil Crops Research DepartmentPlant Pathology Research InstituteAgricultural Research CenterGiza 12619Egypt Bioprocess Development Department Genetic Engineering and Biotechnology Research InstituteCity of Scientific Research and Technological ApplicationsNew Borg El-Arab CityAlexandria 21934Egypt Chemical engineering Department Faculty of EngineeringJazan UniversityJazan 45142Saudi Arabia Plant Protection and Biomolecular Diagnosis Department Arid Lands Cultivation Research InstituteCity of Scientific Research and Technological ApplicationsNew Borg El-Arab CityAlexandria 21934Egypt

Four isolates of Bacillus subtilis coded,B4,B7,B8 and B10 were examined as biocontrol agents for their abilities and antagonistic effect on the in vitro growth of certain phytopathogenic fungi of peanut,Rhizoctonia solani and sclerotium *** subtilis isolate B4(GenBank accession ***150884)was the highly effective one for inhibiting the fungal mycelial *** fermentation of *** isolate B4 was carried out and the maximum biomass achieved was 4.53 g L-1 at 11 *** subtilis isolate B4 was formulated and evaluated as a biofungicide to reduce peanut soil-borne diseases under greenhouse.and field conditions at the side of Rizolex-T(fungicide)as *** by formulated plant growth-promoting rhizobacteria(PGPR)*** B4 and Rizolex-T in a soil infested with ***,*** and mixture of them were more effective in decreasing percentage of damping-off,root and pod rot disease incidence(%)in greenhouse.and open field environment during the two seasons 2015 and *** by PGPR gave highly dry weight and number of healthy pods compared to control of fungi treatment which was nearby to dry weights of healthy pods achieved by treatments by Rizolex-T in a soil infested with ***,*** and mixture of *** PGPR *** B4 gave higher increasing of yield percentage than treatment by Rizolex-T in the two evaluated seasons 2015 and *** can conclude that the produced bioforumlated agent was more efficient as fungicide when compared with the other chemical synthesized fungicides,safe for human and the environment and economy.

关键词： peanut soil-borne diseases Bacillus subtilis biocontrol fermentation formulation

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Rock composition and origin of the Duwi Formation calcareous rocks, Upper egypt

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Chinese Journal Of Geochemistry 2005年第4期24卷 316-326页

作者： Baioumy H.M. attia A.M. Boulis s.N. Hassan M.s. Helmy M.e. Central Metallurgical Research and Development Institute 87 Helwan Cairo EgyptCentral Metallurgical Research and Development Institute 87 Helwan Cairo EgyptCentral Metallurgical Research and Development Institute 87 Helwan Cairo EgyptCentral Metallurgical Research and Development Institute 87 Helwan Cairo EgyptGeology Dept. Faculty of Science Ain Shams University Abbasia Cairo Egypt

Upper Cretaceous phosphorite beds of the Duwi Formation, Upper egypt, are intercalated with limestone, sandy limestone, marl, calcareous shales, and calcareous sandstone. Calcareous intercalations were subjected to field and detailed petrographic, mineralogical and geochemical investigations in order to constrain their rock composition and origin.; Mineralogically, dolomite, calcite, quartz, francolite.and feldspars are the non-clay minerals. smectite, kaolinite.and illite represent the clay minerals. Major and trace elements can be classified as the detrital and carbonate fractions based on their sources. The detrital fraction includes the elements that are derived from detrital sources, mainly clay minerals and quartz, such as si, Al, Fe, Ti, K, Ba, V, Ni, Co, Cr, Zn, Cu, Zr, and Mo. The carbonate fraction includes the elements that are derived from carbonates, maily calcite.and dolomite, such as Ca, Mg and sr. ; Dolomite occurs as being dense, uniform, mosaic, very fine-to-fine, non-ferroan, and non-stoichiometrical, suggesting its early diagenetic formation in a near-shore oxidizing shallow marine environment. The close association and positive correlation between dolomite.and smectite indicates the role of clay minerals in the formation of dolomite as a source of Mge.an-rich solutions.; Calcareous rocks were deposited in marine, oxidizing and weakly alkaline conditions, marking a semi-arid climatic period. The calcareous/argillaceous alternations are due to oscillations in clay/carbonate ratio.

关键词：岩石埃及石灰质白云石成岩作用

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