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Inflammatory bowel diseases and spondyloarthropathies: From pathogenesis to treatment

World Journal of Gastroenterology 2019年第18期25卷 2162-2176页

作者： George e Fragoulis Christina Liava Dimitrios Daoussis euangelos Akriviadis Alexandros Garyfallos Theodoros Dimitroulas First Department of Propaedeutic Internal Medicine National and Kapodistrian University of Athens"Laiko" General Hospital Institute of Infection Immunity & Inflammation University of Glasgow 4~(th) Department of Internal Medicine Hippokration Hospital School of Medicine Aristotle University of Thessaloniki Department of Internal Medicine Division of Rheumatology Patras University Hospital

Spondyloarthropathies(SpA) include many different forms of inflammatory arthritis and can affect the spine(axial SpA) and/or peripheral joints(peripheral SpA) with Ankylosing spondylitis(AS) being the prototype of the former. extraarticular manifestations, like uveitis, psoriasis and inflammatory bowel disease(IBD) are frequently observed in the setting of SpA and are, in fact, part of the SpA classification criteria. Bowel involvement seems to be the most common of these manifestations. Clinically evident IBD is observed in 6%-14% of AS patients, which is significantly more frequent compared to the general population. Besides, it seems that silent microscopic gut inflammation, is evident in around 60% in AS patients. Interestingly, occurrence of IBD has been associated with AS disease activity. For peripheral SpA, two different forms have been proposed with diverse characteristics. Of note, SpA(axial or peripheral) is more commonly observed in Crohn's disease than in ulcerative colitis. The common pathogenetic mechanisms that explain the link between IBD and SpA are still ill-defined. The role of dysregulated microbiome along with migration of T lymphocytes and other cells from gut to the joint("gut-joint" axis) has been recognized, in the context of a genetic background including associations with alleles inside or outside the human leukocyte antigen system. Various therapeutic modalities are available with monoclonal antibodies against tumour necrosis factor, interleukin-23 and interleukin-17, being the most effective. Both gastroenterologists and rheumatologists should be alert to identify the coexistence of these conditions and ideally follow-up these patients in combined clinics.

关键词： Spondyloarthropathies Axial spondyloarthropathies Peripheral spondyloarthropathies Ankylosing spondylitis Inflammatory bowel disease

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Finite-time Control of Linear Singular Systems with Parametric Uncertainties and Disturbances

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自动化学报 2005年第4期31卷 634-637页

作者： FeNGJun-e WUZhen SUNJia-Bing SchoolofMathematicsandSystemSciences ShandonoUniversityJinan250100 DepartmentofInformationScienceandControlengineering ShandongUniversityWeihai264209

The concept of finite-time stability for linear singular system is induced in this ***-time control problem is considered for linear singular systems with time-varying parametricuncertainties and exogenous disturbances. The disturbance satisfies a dynamical system with para-metric uncertainties. A su?cient condition is presented for robust finite-time stabilization via statefeedback. The condition is translated to a feasibility problem involving restricted linear matrix in-equalities (LMIs). A detailed solving method is proposed for the restricted linear matrix ***, an example is given to show the validity of the results.

关键词：有限时间控制线性单一系统稳定性不确定参数外因扰动

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Behavioral and Neurogenomic Responses to Acoustic and Visual Sexual Cues are Correlated in Female Torrent Frogs

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Asian Herpetological Research 2021年第1期12卷 88-99页

作者： Longhui ZHAO Jichao WANG Yanlin CAI Jianghong RAN Steven e.BRAUTH Yezhong TANG Jianguo CUI Chengdu Institute of Biology Chinese Academy of SciencesChengdu 610041SichuanChina Key Laboratory of Bio-Resource and eco-environment of Ministry of education College of Life SciencesSichuan UniversityChengdu 610041SichuanChina University of the Chinese Academy of Sciences Beijing 100049China Key Laboratory for Tropical Plant and Animal ecology of Ministry of education College of Life SciencesHainan NormalUniversityHaikou 571158HainanChina Department of Psychology University of MarylandCollege ParkMaryland 27042USA

Diverse a nimal species use multimodal communica tion signals to coordina te reproductive *** active research in this field,the brain mechanisms underlying multimodal communication remain poorly *** to humans and many mammalian species,anurans often produce auditory signals accompanied by conspicuous visual cues(e.g.,vocal sac inflation).In this study,we used video playbacks to determine the role of vocal-sac inflation in little torrent frogs(Amolops torrentis).Then we exposed females to blank,visual,auditory,and audiovisual stimuli and analyzed whole brain tissue gene expression changes using *** results showed that both auditory cues(i.e.,male advertisement calls)and visual cues were attractive to female frogs,although auditory cues were more attractive than visual *** preferred simultaneous bimodal cues to unimodal *** hierarchical clustering of differentially expressed genes showed a close relationship between neurogenomic states and momentarily expressed sexual *** also found that the Gene Ontology terms and KeGG pathways involved in energy metabolism were mostly increased in blank contrast versus visual,acoustic,or audiovisual stimuli,indicating that brain energy use may play an important role in response to these *** sum,behavioral and neurogenomic responses to acoustic and visual cues are correlated in female little torrent frogs.

关键词： energy metabolism multimodal communication little torrent frogs neurogenomic states sexual traits

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Soil fungal and prokaryotic community structure exhibits differential short-term responses to timber harvest in the Pacific Northwest

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Pedosphere 2020年第1期30卷 109-125页

作者： Rachel e.DANIeLSON Megan L.MCGINNIS Scott M.HOLUB David D.MYROLD Department of Crop and Soil Science Oregon State UniversityCorvallis OR 97331-7306(USA) United State Forest Service Helena-Lewis and Clark National Forest2880 Skyway DriveHelena MT 59602(USA) Weyerhaeuser Company PO Box 275Springfield OR 97477(USA) Department of Land Airand Water ResourcesUniversity of CaliforniaDavis CA 95616USA

Conventional clear-cut timber harvest is a widespread industrial practice across the Pacific Northwest;however,information regarding how these practices impact soil microbial community structure at the regional scale is *** evidence of consistent and substantial impact of harvest on soil microbial functional profiles across the region(despite a range of environmental conditions),the objective of this study was to determine the extent to which harvest also influences the structure of prokaryotic and fungal soil microbial communities,and how generalized these trends are throughout the geographic *** soil samples were collected one year before and after harvest across nine second-growth Douglas-fir forests in the Pacific *** community DNA was extracted from the soils,and high-throughput targeted gene sequencing of the 16 S r RNA gene for prokaryotes and the internal transcribed spacer(ITS)gene for fungi was *** diversity was consistently and significantly higher after harvest;it was moderately so for fungal communities(+14.6%),but only marginally so for prokaryotic communities(+2.0%).Similarly,on average,a greater proportion of the variation in the community structure of fungi(20.1%)at each site was associated with forest harvest compared to that of prokaryotes(13.2%).Overall,the greatest influence of timber harvest on soil microbial communities appeared to be a relative depletion of ectomycorrhizal fungi,with a concomitant enrichment of saprotrophic *** the short-term responses of soil microbial communities across the region,particularly those of tree root-associated symbionts,may aid our understanding of the role soil microbial communities play in ecological succession.

关键词： clear-cut Douglas-fir forest ectomycorrhizal fungi forest soil microbial community microbial diversity root-associated symbiont saprotrophic fungi

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Study of micro-elongated thermoelastic medium loaded with a piezoelectric layer under the influence of gravity using the dual-phase-lag model

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International Journal of Mechanical System Dynamics 2023年第2期3卷 136-145页

作者： Mohamed I.A.Othman ebtesam e.M.eraki Mohamed F.Ismail Department of Mathematics Faculty of ScienceZagazig UniversityZagazigEgypt Department of engineering Mathematics and Physics Higher Institute of EngineeringShorouk AcademyAl-Shorouk CityEgypt

This paper aims to examine the influence of gravity on a thermoelastic microelongated layer when a piezoelectric layer is above it,utilizing the theory of Lord–Shulman(L–S)and also the model of dual‐phase‐lag(DPL).A partial differential equation was transformed into an ordinary differential equation using the normal mode *** epoxy numerical computations are carried out,and the results are presented in graphical *** L–S theory and the model of DPL are compared in the presence and absence of gravity and it is found that gravity has quite a massive influence on all the physical quantities.

关键词： piezoelectrics normal mode analysis gravity micro‐elongated thermoelastic DPL model

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Imperfect mimicry of host begging calls by a brood parasitic cuckoo:a cue for nestling rejection by hosts?

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Current Zoology 2021年第6期67卷 665-674页

作者： Hee-Jin NOH Ros GLOAG Ana V.LeITAO Naomi e.LANGMORe Research School of Biology Australian National UniversityCanberra ACT 0200Australia School of Life and environmental Sciences University of SydneySydneyNSW 2006Australia School of Biosciences University of MelbourneParkville VIC 3010Australia

Coevolutionary interactions between avian brood parasites and their hosts often lead to the evolution of discrimination and rejection of parasite eggs or chicks by hosts based on visual cues,and the evolution of visual mimicry of host eggs or chicks by brood *** may also base rejection of brood parasite nestlings on vocal cues,which would in turn select for mimicry of host begging calls in brood parasite *** cuckoos that exploit multiple hosts with different begging calls,call structure may be plastic,allowing nestlings to modify their calls to match those of their various hosts,or fixed,in which case we would predict either imperfect mimicry or divergence of the species into host-specific *** our study of the little bronze-cuckoo(LBC)Chalcites minutillus and its primary host,the large-billed gerygone Gerygone magnirostris,we tested whether:(1)hosts use nestling vocalizations as a cue to discriminate cuckoo chicks;(2)cuckoo nestlings mimic the host begging calls throughout the nestling period;and(3)the cuckoo begging calls are plastic,thereby facilitating mimicry of the calls of different *** found that the begging calls of LBCs are most similar to their gerygone hosts shortly after hatching(when rejection by hosts typically occurs)but become less similar as cuckoo chicks get *** call structure may be used as a cue for rejection by hosts,and these results are consistent with gerygone defenses selecting for age-specific vocal mimicry in cuckoo *** found no evidence that LBC begging calls were plastic.

关键词： begging call bronze-cuckoo brood parasitism coevolution gerygone

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THeOReTIC SOLUTION OF TRANSIeNT FLOW OF LIQUID IN THe PIPe WITH FLUID MACHINeRY

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Journal of Hydrodynamics 1992年第4期4卷 119-126页

作者： Chen Jin-e Shanghai Institute of electric Power,Shanghai 200090,P.R.China

The transient flow of liquid in the pipe with fluid machinery is analysed in this pa- *** theoretic solution of the transient flow produced due to the regulation of fluid machin- ery is found by use of the method of t... 详细信息

关键词： transient flow liquid fluid machinery

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Bilateral same-session intravitreal injections of antivascular endothelial growth factors

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International Journal of Ophthalmology(english edition) 2014年第6期7卷 1017-1021页

作者： Nakhleh e.Abu-Yaghi Ahmed N Shokry Rami H Abu-Sbeit Department of Ophthalmology Faculty of Medicinethe University of Jordan

AIMTo document the indications, safety and possible complications of bilateral same-session intravitreal anti-vascular endothelial growth factor (VeGF) injections performed in the ophthalmic operating room.

关键词： anti-vascular endothelial growth factor diabetic macular edema age-related macular degeneration endophthalmitis visual acuity

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Prediction of protein and amino acid composition and digestibility in individual feedstuffs and mixed diets for pigs using near-infrared spectroscopy

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Animal Nutrition 2021年第4期7卷 1242-1252页

作者： Samantha J.Noel Henry J.Høgh Jørgensen Knud e.Bach Knudsen Department of Animal Science AU FoulumAarhus UniversityDK 8830TjeleDenmark

Knowledge of the amounts and digestibility of amino acids in pig feedstuffs is essential for calculating the appropriate inclusion level in a complete *** chemical analysis and in vivo digestibility trials are time-consuming and costly and cannot be used for routine ***-infrared spectroscopy(NIRS)offers a rapid,cost effective and environmentally friendly method for evaluating *** models were developed using NIRS to predict the content of crude protein and 18 amino acids from a wide range of feedstuffs used in pig production(n=607).The samples ranged from single feed ingredients(containing amino acids from 0.3 to 129.8 g/kg of dry matter)to feed mixtures(containing amino acids from 1.2 to 53.2 g/kg of dry matter).The predictive ability of the calibrations was tested with an independent dataset(n=150)and with ***,we compare these calibrations with calibrations developed on more narrowly defined groups of samples and with predictions from regression analysis of crude *** models were able to predict the concentrations of crude protein and 18 amino acids with good levels of precision and high coefficients of determination for calibration(RSQ^(CAL))from 0.91 to 0.99 and validation(RSQ^(VAL))from 0.87 to *** models were able to predict all amino acids except tryptophan and valine with greater accuracy than those from protein *** also developed calibration models to predict the apparent ileal and total tract digestibility of protein and amino *** the exception of tryptophan,RSQ values(>0.7)and standard error of cross validation(SeCV)values(ere obtained for the digestibility of most of the amino *** conclusion,NIRS can be used to predict crude protein and amino acid concentrations from a wide range of single ingredients and feed mixtures used for pig diets without separate models for each *** digestibility of protein and amino acids can be predicted with an

关键词： Near-infrared spectroscopy Amino acids Protein Apparent ileal digestibility Total tract digestibility Swine

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Influence of Skidding Operation on Forest Soil Respiration for Small Four-wheeled Tractors

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Journal of Harbin Institute of Technology(New Series) 2013年第1期20卷 97-100页

作者： De-Ling Yang Li-Hai Wang Wen-Shu Lin Shu-e Ji College of engineering and Technology Northeast Forestry University College of Automobile and Traffic engineering Heilongjiang Institute of Technology

The TJSD-750-Ⅱ type compactness measurement instrument and Li-8100 soil carbon flux automatic measurement system are used to measure soil compactness and soil respiration rate at different skidding roads. A regression model is established to analyze the correlation between soil respiration and its influencing factors. The results shows that the soil compaction on the main skidding road and sub skidding roads are larger than the control points, and the soil compaction on the main skidding road is larger than that on sub skidding roads. The higher the soil compactness is, the lower the rate of soil respiration is. This also leads to the lower sensitivity of soil respiration rate influenced by temperature and humidity.

关键词： skidding road soil compaction soil respiration

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