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Response of primiparous and multiparous buffaloes to yeast culture supplementation during early and mid-lactation

Animal Nutrition 2017年第4期3卷 411-418页

作者： Hanne H.Hansen Nasr e.el-Bordeny Hossam M.ebeid Department of Veterinary and Animal Sciences Center for Herd-Oriented EducationResearch and DevelopmentUniversity of Copenhagen Animal Production Department Faculty of AgricultureAin Shams University Department of Dairy Sciences National Research Centre

Strains of live Saccharomyces cerevisiae yeast have exhibited probiotic effects in ruminants. This study investigated the effects of the dietary yeast supplement, S. cerevisiae(Yea-Sacc^(1026)), on primiparous(PP)and multiparous(MP) egyptian buffaloes in early to mid-lactation. Lactating buffaloes were fed either a basal total mixed ration(TMR, control; 4 PP and 8 MP) or the basal TMR plus 10 g Yea-Sacc^(1026) per buffalo cow per day(yeast; 4 PP and 8 MP). The feeds were given from 15 days prepartum to 180 days postpartum. Feed intake, body weight, and milk yields(MY) were recorded, and milk and blood samples were collected for analyses. Feces were collected from days 45 to 47 during early lactation and from days 90 to92 during mid-lactation to determine apparent digestibility of dry matter(DM), organic matter(OM),crude protein(CP) and crude fiber(CF). energy corrected milk yield(eCM), feed conversion, and energy and nitrogen conversion efficiency were calculated. Yeast treated MP buffaloes consumed more DM(P e untreated control group. Apparent digestibility of DM and OM were significantly greater at mid-lactation for treated versus control group(P = 0.001). Crude fiber digestibility was greater in MP than in PP buffaloes(P = 0.049), and yeast supplemented MP cows had a greater CF digestibility than control MP buffaloes at mid-lactation(P = 0.010). Total blood lipids decreased after yeast supplementation(P= 0.029). Milk yields, eCM, fat and protein yields increased for yeast treated MP buffaloes(P e study concluded that the response to yeast supplementation in buffalo cows is parity dependent. Multiparous buffaloes respond to yeast supplementation with an increased DM intake and CF digestibility without significant weight gains, allowing a greater eCM yield with less fat mobilization. Supplementing buffaloes with yeast culture may increase milk production in early lactation and results in a more persistent milk production during mi

关键词： Multiparous buffalo cows Yeast Saccharomyces cerevisiae Feed additive Primiparous buffalo cows

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Aggregation-induced emission of copper nanoclusters

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Aggregate 2021年第6期2卷 28-42页

作者： Yu-e Shi Jinzhu Ma Anrui Feng Zhenguang Wang Andrey L.Rogach Key Laboratory of Chemical Biology of Hebei Province Key Laboratory of Medicinal Chemistry and Molecular DiagnosisMinistry of EducationCollege of Chemistry&Environmental ScienceHebei UniversityBaodingP.R.China Department of Materials Science and engineering&Centre for Functional Photonics(CFP) City University of Hong KongKowloonHong KongS.A.R.P.R.China

Copper nanoclusters(Cu NCs)have recently emerged as promising luminophores,featuring ultra-small size,reasonable photostability,large Stokes shift,and long emission ***-induced emission(AIe)has been often used to further improve both the emission intensity and stability of these clusters,with plenty of potential applications in the fields of chemical sensing and *** review starts with a summary of the current understanding of emission mechanisms of Cu NCs and proceeds with the analysis of contributions from the Cu metal core and the organic *** summarize the recent research progress on the design of ligands,and the ways on how to induce aggregation of the Cu NCs through electrostatic charge neutralization,host-guest interactions,and the use of *** also discuss the current understanding of emission mechanisms of Cu NCs experiencing AIe,such as the often-cited restriction of intramolecular motion and contributions from Cu(I)molecular *** finish this review by providing concluding remarks and offering our own perspective on the active field of AIe of Cu NCs,with a hope to further promote the research on the fundamental aspects of this useful phenomenon.

关键词： aggregation-induced emission copper nanoclusters surface ligands

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Polarization reversal via a transient relaxor state in nonergodic relaxors near freezing temperature

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Journal of Materiomics 2019年第4期5卷 634-640页

作者： Chang-Hyo Hong Hanzheng Guo Xiaoli Tan John e.Daniels Wook Jo School of Materials Science and engineering Ulsan National Institute of Science and TechnologyUlsan44919Republic of Korea Department of Materials Science and engineering Iowa State UniversityAmesIA50011USA School of Materials Science and engineering University of New South WalesNew South Wales2052Australia

Among the unresolved issues in the study of relaxor ferroelectrics is the role of freezing temperature,across which the dynamics of polarization reversal in relaxor ferroelectrics *** presence of this freezing temperature is best manifested by the appearance of a double polarization hysteresis loop just above the freezing *** that the polarization pinching evolving into a double hysteresis starts well below the freezing temperature,there exists a transient temperature regime between the nonergodic and the ergodic relaxor *** clarify the role of the freezing temperature on the pinching,the polarization reversal near the freezing temperature of relaxor(Pb_(1-x)La_(x))(Zr_(1-y)T_(y))_(1-x/4)O_(3)(PLZT)was monitored using three in situ electric field methods:electrocaloric effect,neutron diffraction,and transmission electron *** demonstrate that the pinching results from a two-step process,1)domain detexturization in the ferroelectric state and 2)miniaturization of *** observation explains the recently reported gap between the depolarization temperature T_(d) and the ferroelectric-torelaxor transition temperature T_(F-R) in lead-free *** further show that T_(d) and T_(F-R),which have long been considered identical in lead-based relaxors,are not the *** current study suggests that the mismatch between T_(d) and TF-R is an inherent feature in both lead-based and lead-free relaxor ferroelectrics.

关键词： Relaxor Nanodomains In situ Neutron diffraction Transmission electron microscopy

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A co-infection model for HPV and syphilis with optimal control and cost-effectiveriess analysis

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International Journal of Biomathematics 2021年第7期14卷 1-44页

作者： A.Omame D.Okuonghae U.e.Nwafor B.U.Odionyenna Department of Mathematics Federal University of Technology OwerriNigeriai Department of Mathematics University of Benin Benin CityNigeria

A co-infection model for human papillomavirus(HPV)and syphilis with cost-effectiveness optimal control analysis is developed and *** full co-infectionmodel is shown to undergo the phenomenon of backward bifurcation when a certain con-dition is *** global asymptotic stability of the disease-free equilibrium of thefull model is shown not to exist when the associated reproduction number is less *** existence of endemic equilibrium of the syphilis-only sub-model is shown toexist and the global asymptotic stability of the disease-free and endemic equilibria of thesyphilis-only sub-model was established,for a special *** analysis is alsocarried out on the parameters of the *** the syphilis associated reproductionnumber,R_(0s),as the response function,it is observed that the five-ranked parametersthat drive the dynamics of the co-infection model are the demographic parameter μ,the efective contact rate for syphilis transmission,β_(s),the progression rate to late stage ofsyphilis σ2,and syphilis treatment rates:τ1 and τ2 for co-infected individuals in com-partments Hi and Hl,***,when the HPV associated reproductionnumber,R0h,is used as the response function,the five most dominant parameters thatdrive the dynamics of the model are the demographic parameter μ,the effective contactrate for HPV transinission,β_(h),the fraction of HPV infected who develop persistent HPV p1,the fraction of individuals vaccinated against incident HPV infection φ and the HPVvaccine eflicacy π*** simulations of the optimal control model showed that theoptimal control strategy which implements syphilis treatment controls for singly infectedindividuals is the most cost-effective of all the control strategies in reducing the burdenof HPV and syphilis co-infections.

关键词： Human papillomavirus syphilis co-infection optimal control cost-effectiveness analysis

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Cluster size distribution of cancer cells in blood using stopped-flow centrifugation along scale-matched gaps of a radially inclined rail

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Microsystems & Nanoengineering 2015年第1期1卷 97-105页

作者： Macdara Glynn Charles Nwankire Kate Lemass David J.Kinahan Jens Ducrée Biomedical Diagnostics Institute National Centre for Sensor ResearchSchool of Physical SciencesDublin City UniversityIreland

There is increasing evidence that,in addition to their presence,the propensity of circulating tumour cells to form multi-cellular clusters bears significant information about both cellular resistance to chemotherapy and overall *** present a novel two-stage,stopped-flow,continuous centrifugal sedimentation strategy to measure the size distributions of events(defined here as cells or clusters thereof)in a blood *** off-chip removal of red blood cells,healthy white blood cells are sequestered by *** purified events are then resolved along a radially inclined rail featuring a series of gaps with increasing width,each connected to a designated outer collection *** isolation of candidate events independent of targetspecific epitopes is successfully demonstrated for HL60(epCAM positive)and sk-mel28(epCAM negative)cells using identical protocols and *** propensity to form clusters was quantified for a number of cell lines,showing a negligible,moderate or elevated tendency towards cluster *** show that the occupancy distribution of the collection bins closely correlates with the range of cluster sizes intrinsic to the specific cell line.

关键词： centrifugal microfluidics lab-on-a-disc cancer diagnostics cellular clustering

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Development of collagenous colitis in inflammatory bowel disease:two case reports and a review of the literature

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Gastroenterology Report 2019年第3期7卷 218-222,I0003页

作者： Rahoma e.Saad Rima M.Shobar Shriram Jakate ece A.Mutlu Graduate College Rush UniversityChicagoILUSA Department of Pathology Rush UniversityChicagoILUSA Department of Medicine Division of Gastroenterology and NutritionRush UniversityChicagoILUSA

The occurrence of collagenous colitis(CC)in patients with pre-existing inflammatory bowel diseases(IBD)is rare,with only seven cases reported in the ***,we report two IBD cases who developed CC after successful treatment of their IBD with two different tumor necrosis factor(TNF)-a inhibitors,which have been previously reported to successfully treat refractory *** report highlights the need to do random biopsies of the colon for CC diagnosis in IBD patients with symptoms of diarrhea after complete mucosal *** report also reviews plausible mechanisms as to how CC may develop,including the role of multiple medications.

关键词： Collagenous colitis inflammatory bowel disease tumor necrosis factor-a inhibitors infliximab adalimumab

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Assessment of alternated cooling and heating treatment by US combined CeUS in the VX2 rabbit liver tumor model

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Chinese Science Bulletin 2014年第9期59卷 865-873页

作者： Cong Wei e.Shen Di Sun Aili Zhang Jianqi Sun Bing Hu Department of Ultrasound in Medicine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai Institute of Ultrasound in Medicine Department of Biomedical engineering and Med-X Research Institute Shanghai Jiao Tong University

Inoperable liver tumors are often treated by thermal ablation that destroys the tumor in situ and spares the adjacent hepatic ***–physical treatment has many advantages,but treatment by freezing or heating alone has some *** taking the advantages and disadvantages of cryosurgery and thermotherapy into consideration,a new thermal technique that combines cryosurgery and radio frequency ablation has been proposed,thereby overcoming the disadvantages of each treatment strategy and improving therapeutic *** new approach remains to be systematically studied in the liver;therefore,this study was performed to estimate survival after alternated cooling and heating ablation therapy in a VX2 rabbit liver tumor *** days after VX2 carcinoma implantation into the rabbit liver,tumors were treated with alternated cooling and heating ablation *** were monitored for 6 months after treatment and assessed with ultrasound(US)and computed tomography at 1,7,14,and 30 days *** tumor-bearing animals served as the control *** results show that alternate freezing and heating ablation therapy resulted in a good recovery of VX2 *** with the control group,treated rabbits lived significantly longer(P\0.05),with 70%of treated animals surviving to 196 days posttreatment without metastasis or recurrence,while none of the controls did *** was no local recurrence in the treatment *** rabbits in the control group developed metastasis,while metastasis was only observed in 30% of treated *** results suggest that alternate cooling and heating ablation therapy can prolong the survival time of rabbits with VX2 liver tumors and is an effective method for tumor ***,we also showed in this model that contrast enhanced US is a valid follow-up approach to assess treatment effectiveness.

关键词：物理治疗肿瘤模型肝肿瘤后评估兔肝加热美国超声

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effects of Root Cutting on Morphological Characteristics and endogenous Hormone Levels of Quercus variabilis Seedlings

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国际实验植物学杂志(英文) 2023年第10期92卷 2907-2920页

作者： Ruoyi Ni Hao Dou Shuwen Bi Tiantian Wang Jin’e Quan Xitian Yang College of Forest Henan Agricultural UniversityZhengzhou450002China

The objective of this study was to investigate the effects of root cutting stress on the dynamic changes of endogenous hormone content and growth characteristics of Quercus variabilis roots,and to explore the physiological role of endogenous hormones in regulating root-crown interactions in the short *** morphological characteristics and endogenous hormone contents of normal roots(no root cutting,CK)and cut roots(cut by 1/3 of the length of the main root,RP)were determined by liquid chromatography,which was combined with mass spectrometry at different levels of different developmental *** results showed that the root growth indexes and root endogenous hormones in the RP group were superior to those in the CK *** comprehensive analysis of endogenous hormones,it was found that the crosstalk of IAA,JA,ABA and SA could activate the root growth *** the root cutting treatment,the root growth of Quercus variabilis seedlings could compensate for the inhibition of taproot growth by promoting lateral root *** growth and development of compensatory lateral roots contribute to the increase the total root length of plants,thus promoting the absorption of water and *** is speculated that plant hormones may be the key factors affecting their development,but this is not only related to the content of a single hormone,but more importantly,it is the interaction between various hormones.

关键词： Quercus variabilis root cutting injury endogenous hormones root morphology

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Advances in healthcare wearable devices

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npj Flexible electronics 2021年第1期5卷 73-86页

作者： Sheikh M.A.Iqbal Imadeldin Mahgoub e Du Mary Ann Leavitt Waseem Asghar Department of Computer and electrical engineering&Computer Science Florida Atlantic UniversityBoca RatonFLUSA Asghar-Lab Micro and Nanotechnology in MedicineCollege of Engineering and Computer ScienceBoca RatonFLUSA Department of Ocean and Mechanical engineering Florida Atlantic UniversityBoca RatonFLUSA Christine e.Lynn College of Nursing Florida Atlantic UniversityBoca RatonFLUSA Department of Biological Sciences(Courtesy appointment) Florida Atlantic UniversityBoca RatonFLUSA

Wearable devices have found numerous applications in healthcare ranging from physiological diseases,such as cardiovascular diseases,hypertension and muscle disorders to neurocognitive disorders,such as Parkinson’s disease,Alzheimer’s disease and other psychological *** types of wearables are used for this purpose,for example,skin-based wearables including tattoobased wearables,textile-based wearables,and biofluidic-based ***,wearables have also shown encouraging improvements as a drug delivery system;therefore,enhancing its utility towards personalized *** wearables contain inherent challenges,which need to be addressed before their commercialization as a fully personalized healthcare *** paper reviews different types of wearable devices currently being used in the healthcare *** also highlights their efficacy in monitoring different diseases and applications of healthcare wearable devices(HWDs)for diagnostic and treatment ***,current challenges and limitations of these wearables in the field of healthcare along with their future perspectives are also reviewed.

关键词： wear healthcare challenges

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God, belief, and perplexity

God, belief, and perplexity

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作者： William e. Mann.

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