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nanomotion of bacte.ia to de.e.mine.me.abolic profile

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nanote.hnology and Pre.ision e.gine.ring 2024年第1期7卷 1-9页

作者： S.n.Ple.kova e.V.Lazare.ko n.A.Be.rukov R.n.Kriukov A.V.Boryakov M.e.Dokukin S.I.Surodin Re.e.rch Laboratory of Scanning Probe.Microscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia De.artme.t of nanote.hnology and Biote.hnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics and Te.hnology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to the.r visible.motion such as swimming(e.g.,with the.he.p ofﬂage.la),bacte.ia can also e.hibit nanomotion that is de.e.table.only with highly se.sitive.instrume.ts,and this study shows that it is possible.to de.e.t bacte.ial nanomotion using an AFM de.e.tion *** re.ults show that the.nanomotion characte.istics de.e.d on the.bacte.ial strain,and that nanomotion can be.use. to se.se.the.me.abolic activity of bacte.ia be.ause.the.oscillations are.se.sitive.to the.food pre.e.e.ce. of the.bacte.ia and the.type.of surrounding me.ium.

关键词： nanomotion Bacte.ia Cantile.e. Oscillation Atomic force.microscopy Me.abolism

In vivo astrocyte.re.rogramming following spinal cord injury

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ne.ral Re.e.e.ation Re.e.rch 2024年第3期19卷 487-488页

作者： Yannick n.Ge.be. Flore.ce.e.Pe.rin MMDn University of MontpellierEPHEINSERMMontpellierFrance Institut Unive.sitaire.de.France.IUF) ParisFrance

Harmful and he.pful role. of astrocyte. in spinal cord injury(SCI):SCI induce.gradable.se.sory,motor and autonomic impairme.ts that corre.ate.with the.le.ion se.e.ity and the.rostro-caudal location of the.injury *** abse.ce.of spontane.us axonal re.e.e.ation afte. injury re.ults from ne.ron-intrinsic and ne.ron-e.trinsic ***,not only adult ne.rons display limite. capability to re.row axons but also the.injury e.vironme.t contains inhibitors to axonal re.e.e.ation and a lack of growth-promoting *** othe. ce.l populations that re.pond to the.le.ion,re.ctive.astrocyte. we.e.first conside.e. as only de.rime.tal to spontane.us axonal ***,astrocyte..

关键词： injury impairme.t programming

RBC aggre.ation,de.ormation and adhe.ion to e.dothe.ium:Role.of nitric oxide.de.ive. from L-Arginine.and sodium nitroprusside

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Journal of Innovative.Optical He.lth Scie.ce. 2024年第5期17卷 53-65页

作者： M.K.Maksimov P.B.e.molinskiy O.n.Sche.lovitova n.n.Sklyankina A.V.Muravyov A.e.Lugovtsov A.V.Prie.zhe. Faculty of Physics M.V.Lomonosov Moscow State University bld.1subbuilding.2Leninskie goryMoscow 11991Russia n.F.Gamale.a national Re.e.rch Ce.te. for e.ide.iology and Microbiology 18 Gamaleya StreetMoscow 123098Russia K.D.Ushinsky Yaroslavl State.Pe.agogical Unive.sity 108/1 Respublikanskaya StreetYaroslavl 150000Russia

Re. blood ce.ls(RBCs)are.the.most abundant human blood *** aggre.ation and de.ormation strongly de.e.mine.blood viscosity which impacts he.orhe.logy and *** turn,RBC prope.tie. de.e.d on di®e.e.t e.doge.ous and e.oge.ous *** such factor is nitric oxide.nO),which is mainly produce. by e.dothe.ial ce.ls(e.)from L-arginine.amino acid in the.circulatory *** the.me.hanisms of the.RBC-e.dothe.ium inte.play are.not cle.r up to date.and conside.ing its possible.clinical importance.the.aims of this study are.to inve.tigate.in vitro:(1)The.e.e.t of L-arginine.induce. nO on RBC aggre.ation and adhe.ion to e.dothe.ium;(2)the.nO e.e.t on RBC aggre.ation and de.ormation induce. by L-arginine.and sodium nitroprusside.without the.pre.e.ce.of e.dothe.ium in the.*** RBC aggre.ation and adhe.ion to a monolaye. of e. we.e.studie. using optical twe.ze.s(OT).The.RBC de.ormability and aggre.ation without e.dothe.ium in the.sample. we.e.studie. using the.ow chambe. me.hod and Myre.ne.*** con¯rme. that nO incre.se. de.ormability and de.re.se. aggre.ation of *** showe. that the.soluble.guanylate.cyclase.pathway appe.rs to be.the.only nO signaling pathway *** the.sample. with the.e.dothe.ium,the.be.l-shape."de.e.de.ce.of RBC aggre.ation force.on L-arginine.conce.tration was obse.ve.,which improve. our knowle.ge.about the.proce.s of nO production by ***,data re.ate. to L-arginine.accumulation by e.dothe.ium we.e.obtaine.:ne.e.sity of the.pre.e.ce.of e.trace.lular L-arginine.state. by othe. authors was put unde. *** our study,nO de.re.se. the.RBC-e.dothe.ium adhe.ion,howe.e.,the.te.de.cy appe.re. to be.we.k and was not con¯rme. in anothe. se. of *** our knowle.ge.this is the.rst atte.pt to me.sure.the.force. of RBC adhe.ion to e.dothe.ium monolaye. with OT.

关键词： Re. blood ce.ls aggre.ation L-arginine e.dothe.ium optical twe.ze.s Myre.ne flow chambe.

Che.yshe. polynomial-base. Ritz me.hod for the.mal buckling and fre. vibration be.aviors of me.al foam be.ms

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Applie. Mathe.atics and Me.hanics(e.glish e.ition) 2024年第5期45卷 891-910页

作者： n.D.nGUYe. T.n.nGUYe. Faculty of Civil e.gine.ring Ho Chi Minh City University of Technology and EducationHo Chi Minh City 71309Viet Nam Faculty of e.gine.ring and Te.hnology Kien Giang UniversityChau Thanh 92000Viet Nam

This study pre.e.ts the.Che.yshe. polynomials-base. Ritz me.hod to e.amine.the.the.mal buckling and fre. vibration characte.istics of me.al foam *** analyse. include.thre. mode.s for porosity distribution and two sce.arios for the.mal *** mate.ial prope.tie. are.asse.se. unde. two conditions,i.e.,te.pe.ature.de.e.de.ce.and te.pe.ature.*** the.re.ical frame.ork for the.be.ms is base. on the.highe.-orde. she.r de.ormation the.ry,which incorporate. she.r de.ormations with highe.-orde. *** gove.ning e.uations are.e.tablishe. from the.Lagrange.e.uations,and the.be.m displace.e.t fie.ds are.approximate. by the.Che.yshe. *** simulations are.pe.forme. to e.aluate.the.e.fe.ts of the.mal load,sle.de.ne.s,boundary condition(BC),and porosity distribution on the.buckling and vibration be.aviors of me.al foam *** findings highlight the.significant influe.ce.of te.pe.ature.de.e.de.t(TD)mate.ial prope.tie. on me.al foam be.ms'buckling and vibration re.ponse..

关键词： Ritz me.hod Che.yshe. function buckling vibration me.al foam be.m highe.-orde. be.m the.ry(HOBT)

Landau quantization e.fe.ts on damping Kawahara solitons in e.e.tron–positron–ion plasma in rotating ionize. me.ium

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Communications in The.re.ical Physics 2024年第10期76卷 143-152页

作者： e.I e.-Awady S Hussain n Akhtar De.artme.t of Physics Faculty of Science Port Said University The.re.ical Physics Division (TPD) PINSTECH

For the.dynamics of thre.-dime.sional e.e.tron–positron–ion plasmas, a fluid quantum hydrodynamic mode. is propose. by conside.ing Landau quantization e.fe.ts in de.se.***–ne.tral collisions in the.pre.e.ce.of the.Coriolis force.are.also conside.e.. The.application of the.re.uctive.pe.turbation te.hnique.produce. a wave.e.olution e.uation re.re.e.te. by a dampe. Korte.e.–de.Vrie. e.uation. This e.uation, howe.e., is insufficie.t for de.cribing wave. in our syste. at ve.y low dispe.sion coe.ficie.ts. As a re.ult, we.conside.e. the.highe.t-orde. pe.turbation, which re.ulte. in the.dampe. Kawahara e.uation. The.e.fe.ts of the.magne.ic fie.d, Landau quantization, the.ratio of positron de.sity to e.e.tron de.sity, the.ratio of positron de.sity to ion de.sity, and the.dire.tion cosine.on line.r dispe.sion laws as we.l as soliton and conoidal solutions of the.dampe. Kawahara e.uation are.e.plore.. The.unde.standing from this re.e.rch can contribute.to the.broade. fie.d of astrophysics and aid in the.inte.pre.ation of obse.vational data from white.dwarfs.

关键词： Coriolis force Kawahara e.uation Landau quantization magne.oplasmas quantum plasma solitary and cnoidal wave.

ne. tre.ds in diagnosis and manage.e.t of gallbladde. carcinoma

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World Journal of Gastrointe.tinal Oncology 2024年第1期16卷 13-29页

作者： e.stathios T Pavlidis Ioannis n Galanis The.doros e.Pavlidis ^(nd)Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladde.(GB)carcinoma,although re.ative.y rare.is the.most common biliary tre. cholangiocarcinoma with aggre.sive.e.s and poor *** is close.y associate. with chole.ithiasis and long-standing large.>3 cm)gallstone. in up to 90%of *** othe. main pre.isposing factors for GB carcinoma include.mole.ular factors such as mutate. ge.e.,GB wall calcification(porce.ain)or mainly mucosal microcalcifications,and GB polyps≥1 cm in *** is made.by ultrasound,compute. tomography(CT),and,more.pre.ise.y,magne.ic re.onance.imaging(MRI).Pre.pe.ative.staging is of gre.t importance.in de.isionmaking re.arding the.ape.tic *** staging is base. on MRI findings,the.le.ding te.hnique.for live. me.astasis imaging,e.hance. thre.-phase.CT angiography,or magne.ic re.onance.angiography for major ve.se. *** is also ne.e.sary to use.positron e.ission tomography(Pe.)-CT or ^(18)F-FDG Pe.-MRI to more.accurate.y de.e.t me.astase. and any othe. occult de.osits with active.me.abolic *** laparoscopy may de.e.t disse.ination not othe.wise.found in 20%-28.6%of *** tre.tme.t is ne.de.,including surgical re.e.tion,targe.e. the.apy by biological age.ts according to mole.ular te.ting ge.e.mapping,che.othe.apy,radiation the.apy,and *** is of gre.t importance.to unde.stand the.update. guide.ine. and curre.t tre.tme.t *** e.te.t of surgical inte.ve.tion de.e.ds on the.dise.se.stage.ranging from simple.chole.yste.tomy(T1a)to e.te.de. re.e.tions and including e.te.de. chole.yste.tomy(T1b),with wide.lymph node.re.e.tion in e.e.y case.or IV-V se.me.te.tomy(T2),he.atic trise.me.te.tomy or major he.ate.tomy accompanie. by he.aticoje.unostomy Roux-Y,and adjace.t organ re.e.tion if ne.e.sary(T3).Laparoscopic or robotic surge.y shows fe.e. postope.ative.complications and e.uivale.t oncological outcome. whe. compare. to ope. surge.y,but much atte.tion must be.paid to avoiding *** addition to surge.y,nove. targe

关键词： Biliary tract ne.plasms e.trahe.atic cholangiocarcinoma Gallbladde. carcinoma Gallbladde. dise.se. Biliary tre. dise.se. Gastrointe.tinal malignancie.

Manage.e.t of obstructe. colore.tal carcinoma in an e.e.ge.cy se.ting:An update

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World Journal of Gastrointe.tinal Oncology 2024年第3期16卷 598-613页

作者： e.stathios T Pavlidis Ioannis n Galanis The.doros e.Pavlidis 2nd Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colore.tal carcinoma is common,particularly on the.le.t *** 20%of patie.ts,obstruction and ile.s may be.the.first clinical manife.tations of a carcinoma that has advance.(stage.II,III or e.e. IV).Diagnosis is base. on clinical pre.e.tation,plain abdominal radiogram,compute. tomography(CT),CT colonography and positron e.ission tomography/*** be.t manage.e.t strate.y in te.ms of short-te.m ope.ative.or inte.ve.tional and long-te.m oncological outcome. re.mains *** the.most common le.t-side. obstruction,the.first choice.should be.e.the. e.e.ge.cy surge.y or e.doscopic de.ompre.sion by se.f-e.pe.-dable.me.al ste.ts or *** ope.ative.plan should be.e.the. one.stage.or two-stage.***-stage.re.e.tion with on-table.bowe. de.ompre.sion and irrigation can be.accompanie. or not accompanie. by proximal de.unctioning stoma(colostomy or ile.stomy).Primary anastomosis is more.conve.ie.t but has incre.se. risks of anastomotic le.kage.and ***-stage.re.e.tion(Hart-mann’s proce.ure.is safe. and the.most wide.y use. de.pite.te.porally affe.ting quality of *** control surge.y in high-risk frail patie.ts is le.s fre.ue.tly pe.forme. since.it can be.succe.sfully substitute. with e.doscopic ste.ting or *** the.le.s common right-side. obstruction,one.stage.surgical re.e.tion is more.be.e.icial than e.doscopic *** role.of minimally invasive.surge.y(laparoscopic or robotic)is a subje.t of *** laparoscopic-assiste. manage.e.t is advantage.us to some.e.te.t but re.uire. much e.pe.tise.due.to inhe.e.t difficultie. in disse.ting the.diste.de. colon and the.risk of rup-ture.and subse.ue.t se.tic *** de.ompre.sing ste.t as a bridge.to e.e.tive.surge.y more.substantially de.re.se. the.risks of morbidity and mortality than e.e.ge.cy surge.y for de.ompre.sion and has e.uivale.t me.ium-te.m ove.all survival and dise.se.fre. survival *** combination with ne.adjuvant che.othe.apy or radiation may have.a p

关键词： Acute.abdome. Obstructive.ile.s Colore.tal carcinoma e.e.ge.cy surge.y Cole.tomy Intraluminal me.al ste.ts

First re.ults of turbule.ce.inve.tigation on Globus-M2 using radial corre.ation Dopple. re.le.tome.ry

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Plasma Scie.ce.and Te.hnology 2024年第10期26卷 49-55页

作者： A.POnOMARe.KO A.YASHIn V.GUSe. e.KISe.e. G.KURSKIe. V.MInAe. Y.Pe.ROV n.SAKHAROV P.SHCHe.OLe. e.TKACHe.KO n.ZHILTSOV Pe.e. the.Gre.t St.Pe.e.sburg Polyte.hnic Unive.sity St.Petersburg 195251Russia Ioffe.Institute St.Petersburg 194064Russia

The.first re.ults of inve.tigation of the.turbule.ce.structure.using Dopple. backscatte.ing(DBS)on the.Globus-M2 tokamak are.pre.e.te..A one.channe. DBS syste. with a variable.probing fre.ue.cy within the.18–26 GHz range.was installe. to inve.tigate.the.e.ge.plasma at normalize. minor radiiρ=0.9–*** corre.ation Dopple. re.le.tome.ry was use. to study the.change. in turbule.ce.e.die. afte. the.LH *** analysis was applie. to the.phase.de.ivative.of comple. in-phase.and quadrature.IQ)signals of the.DBS diagnostic as it contains information about the.poloidal plasma rotation *** L-mode.the.radial corre.ation le.gth L_(r)is e.timate. to be.3 cm and afte. transition to H-mode.re.uce. to approximate.y 2 *** mode.ling in a line.r local approximation using code.Ge.e.indicate. that the.instability with positive.growth rate.at the.normalize. minor radiusρ=0.75 in L-mode.and H-mode.on Globus-M2 was the.ion te.pe.ature.gradie.t(ITG)mode.

关键词： tokamak turbule.ce Dopple. backscatte.ing corre.ation re.le.tome.ry

Curre.t conside.ations on intraductal papillary ne.plasms of the.bile.duct and pancre.tic duct

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World Journal of Gastroe.te.ology 2024年第10期30卷 1461-1465页

作者： e.stathios T Pavlidis Ioannis n Galanis The.doros e.Pavlidis 2^(nd) Prope.e.tic De.artme.t of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Pancre.tobiliary intraductal papillary ne.plasms(IPns)re.re.e.t pre.ursors of pancre.tic cance. or bile.duct cholangiocarcinoma that can be.de.e.te. and *** advance. in diagnostic me.hods,ide.tifying the.e.pre.alignant le.ions is still challe.ging for tre.tme.t *** imaging,biomarke.s and mole.ular te.ts for ge.omic alte.ations can be.use. for diagnosis and *** inte.ve.tion in combination with ne. che.othe.ape.tic age.ts is conside.e. the.optimal tre.tme.t for malignant *** balance.be.we.n the.risk of malignancy and any risk of re.e.tion guide. manage.e.t policy;the.e.ore.tre.tme.t should be.individualize. base. on a me.iculous pre.pe.ative.asse.sme.t of high-risk *** of the.bile.duct is more.aggre.sive.thus,e.rly diagnosis and surge.y are.*** conse.vative.manage.e.t of low-risk pancre.tic branch-duct le.ions is safe.and e.fe.tive.

关键词： Biliary tre. dise.se. Pancre.tic cystic ne.plasms Biliary tract ne.plasms e.trahe.atic cholangiocarcinoma Pancre.tic ade.ocarcinoma