检索结果-南通市图书馆

Asse.sme.t of soil e.osion in a tropical mountain rive. basin of the.southe.n We.te.n Ghats,India using RUSLe.and GIS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ge.scie.ce.Frontie.s 2018年第3期9卷 893-906页

作者： Jobin Thomas Sabu joseph K.P.Thrivikramji e.Re Department of Civil EngineeringIndian Institute of Technology MadrasChennai600036Tamil NaduIndia De.artme.t of e.vironme.tal Scie.ce. University of KeralaThiruvananthapuram695581KeralaIndia Ce.te. for e.vironme.t and De.e.opme.t Thiruvananthapuram695013KeralaIndia

Re.ise. Unive.sal Soil Loss e.uation(RUSLe. mode. couple. with transport limite. se.ime.t de.ive.y(TLSD) function was use. to pre.ict the.longtime.ave.age.annual soil loss, and to ide.tify the.critical e.osion-/de.osition-prone.are.s in a tropical mountain rive. basin, viz., Muthirapuzha Rive. Basin(MRB; are.=271.75 km^2), in the.southe.n We.te.n Ghats, India. Me.n gross soil e.osion in MRB is 14.36 t ha^(-1) yr^(-1), whe.e.s me.n ne. soil e.osion(i.e., gross e.osion-de.osition) is only 3.60 t ha^(-1) yr^(-1)(i.e., roughly 25% of the.gross e.osion). Majority of the.basin are.(~86%) e.pe.ie.ce. only slight e.osion(e.rly 3% of the.are. functions as de.ositional e.vironme.t for the.e.ode. se.ime.ts(e.g., the.te.race. of stre.m re.che., the.ge.tle.plains as we.l as the.foot slope. of the.plate.u scarps and the.te.rain with concordant summits). Although me.n gross soil e.osion rate. in the.natural ve.e.ation be.ts are.re.ative.y highe., compare. to agriculture. se.tle.e.t/built-up are.s and te. plantation, the.se.ime.t transport e.ficie.cy in agricultural are.s and te. plantation is significantly high,re.le.ting the.role.of human activitie. on acce.e.ate. soil e.osion. In MRB, on a me.n basis, 0.42 t of soil organic carbon(SOC) conte.t is be.ng e.ode. pe. he.tare.annually, and SOC loss from the.4th orde. subbasins shows conside.able.diffe.e.ce., mainly due.to the.spatial variability in the.gross soil e.osion rate. among the.sub-basins. The.quantitative.re.ults, on soil e.osion and de.osition, mode.le. using RUSLe.and TLSD, are.e.pe.te. to be.be.e.icial while.formulating compre.e.sive.land manage.e.t strate.ie. for re.ucing the.e.te.t of soil de.radation in tropical mountain rive. basins.

关键词： Soil e.osion RUSLe Transport limite. se.ime.t de.ive.y Muthirapuzha rive. basin We.te.n Ghats Ke.ala

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

自由市场的坠落

Affinity Crosslinking of Y1036 to Ne.ve.Growth Factor Ide.tifie. Pharmacological Targe.ing Domain for Small Mole.ule.Ne.rotrophin Antagonists

作者： (美)约瑟夫 e. 斯蒂格利茨(joseph e. Stiglitz)

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Ne.roscie.ce.& Me.icine 2013年第4期4卷 290-298页

作者： joseph K. e.bl Zoule.ka Abdallah Allison e. Ke.ne.y John A. Scott Gre.ory M. Ross Biology De.artme.t Laurentian University Sudbury Canada Northe.n Ontario School of Me.icine Sudbury Canada Northe.n Ontario School of Me.icine Sudbury Canada Biology De.partme.t Laurentian University Sudbury Canada

Classically, small mole.ule.antagonists have.targe.e. me.brane.bound re.e.tors and intrace.lular e.zyme.targe.s. While.this drug discove.y strate.y is e.tre.e.y succe.sful, the.numbe. of ne. che.ical e.titie. in the.pharmace.tical pipe.ine.is diminishing and comple.e.tary strate.ie. are.in ne.d. A particularly attractive.the.ape.tic strate.y is to ne.tralize.soluble.signalling prote.ns using small mole.ule.. Small mole.ule.base. te.hnologie. have.the.pote.tial to sufficie.tly alte. the.mole.ular topology of a give. ligand and inhibit ligand/re.e.tor inte.actions—e.fe.tive.y ne.tralizing the.ligand’s signalling capacity. Re.e.t te.hnical advance. in the.fie.d of structural biology have.e.able. the.e.ucidation of ligand/re.e.tor comple.e. at atomic re.olution e.abling a de.aile. appre.iation of the.mole.ular inte.actions gove.ning ligand-me.iate. re.e.tor activation. e.ploiting mole.ular mode.ing te.hnique. to study the.e.signalling comple.e. allows for a paradigm shift from “re.e.torce.tric” to “ligandce.tric” scre.ning strate.ie.. Ne.ve.growth factor (NGF) is a prototypical prote.n signalling ligand, which binds two re.e.tors, TrkA and p75NTR. We.first e.plore.the.mole.ular landscape.gove.ning the.ligand/re.e.tor inte.actions of NGF/TrkA and NGF/p75 structure.. Ne.t, we.use.the.re.e.tly re.orte. NGF ne.tralizing small-mole.ule. Y1036, as an affinity probe.to de.e.mine.re.idue. in proximity to the.pharmacological targe.ing domain of NGF and pe.form the.re.ical docking e.pe.ime.ts to pre.ict the.re.idue. which comprise.distinct pharmacological targe.ing domains on the.surface.of NGF. e.ploiting such strate.ie. may facilitate.“ligandce.tric” drug discove.y and could furthe. the.de.e.opme.t of a trophic-factor-se.e.tive.compound such as a BDNF-se.e.tive.antagonist.

关键词： NGF BDNF Inhibitor Antagonist Pain

Biologic Augme.te. Microdrilling Surge.y for Multiple.and Large.Full-Thickne.s Cartilage.Le.ions in the.Kne.: e.rly Clinical and Radiological Re.ults

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Scie.ce 2017年第2期8卷 102-117页

作者： joseph e. Broyle. M. Adaire.O’Brie. Ste.hanie.T. Broyle. M. Patrick Stagg Bone.and Joint Clinic of Baton Rouge Baton Rouge Louisiana USA Pe.nington Biome.ical Re.e.rch Ce.te. Baton Rouge Louisiana USA Me.ical Oncology OLOL Physician Group Baton Rouge Louisiana USA

Background: Various biologic tre.tme.ts are.available.for articular cartilage.le.ions in the.kne., but no one.e.ists that is applicable.to the.full range.of chondral dise.se.and that is compliant with Unite. State. Food and Drug Administration re.ulations. The.aim of this study was to e.aluate.outcome. following microdrilling surge.y augme.te. with postope.ative.inje.tions of bone.marrow aspirate.conce.trate.(BMAC), plate.e. rich plasma (PRP) and hyaluronic acid (HA). Me.hods: e.ghte.n patie.ts with at le.st one.symptomatic, full-thickne.s chondral le.ion unde.we.t arthroscopic microdrilling surge.y. Imme.iate.y following surge.y, patie.ts re.e.ve. an intra-articular inje.tion of fre.h BMAC, PRP, and HA. This inje.tion was re.e.te. once.pe. we.k for 5 conse.utive.we.ks. At 4 and 12 months postope.ative.y, patie.ts re.e.ve. 3 additional we.kly inje.tions for a total of 12 inje.tions. Outcome.Me.sure.: IKDC (Inte.national Kne. Docume.tation Committe.) score., KS (Kne. Socie.y) score. and plain radiographs. Re.ults: The.me.n tre.te. are. was 6.2 ± 4.5 (range. 0.6 - 14.7) cm2. The.me.n pre.pe.ative.IKDC and KS score. (±Se. we.e.43.0 ± 3.2 and 68.3 ± 3.6 re.pe.tive.y. At 24 months postope.ative.y, IKDC and KS score. improve. to 85.3 ± 4.2 and 94.7 ± 4.4, re.pe.tive.y;both change. from base.ine.we.e.significant (p p = 0.05). This change.was gre.te. in patie.ts with pre.pe.ative.JS p for the.diffe.e.ce.be.we.n groups = 0.1). Conclusions: Microdrilling of cartilage.le.ions augme.te. with BMAC, PRP, and HA may be.a viable.tre.tme.t for a range.of chondral dise.se.with good e.rly clinical and radiological re.ults.

关键词： Cartilage Microdrilling Ste. Ce.ls Joint Space

Dire.t radiative.forcing of urban ae.osols ove. Pre.oria(25.75°S, 28.28°e. using Ae.ONe. Sunphotome.e. data:First scie.tific re.ults and e.vironme.tal impact

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of e.vironme.tal Scie.ce. 2014年第12期26卷 2459-2474页

作者： Ayode.e.joseph Ade.ina Kanike.Raghave.dra Kumar Ve.kataraman Sivakumar De.e. Griffith Discipline.of Physics School of Chemistry and Physics College of Agriculture Engineering and Science Westville CampusUniversity of Kwa Zulu–Natal Durban 4000 South Africa Ke. Laboratory for Ae.osol-Cloud-Pre.ipitation of China Me.e.rological Administration School of Atmospheric PhysicsNanjing University of Information Science and Technology Optronic Se.sor Syste.s Council for Scientific and Industrial Research (CSIR)–DPSS Pretoria 0001 South Africa

The.pre.e.t study use. the.data colle.te. from Cime. Sunphotome.e. of Ae.osol Robotic Ne.work（Ae.ONe.） for the.pe.iod from January to De.e.be., 2012 ove. an urban site.Pre.oria（PTR; 25.75°S, 28.28°e. 1449 m above.se. le.e.）, South Africa. We.found that monthly me.n ae.osol optical de.th（AOD, τa） e.hibits two maxima that occurre. in summe.（Fe.ruary） and winte.（August） having value. of 0.36 ± 0.19 and 0.25 ± 0.14,re.pe.tive.y, high-to-mode.ate.value. in spring and the.e.fte., de.re.se. from autumn with a minima in e.rly winte.（June. 0.12 ± 0.07. The.Angstrom e.pone.ts（α440–870） like.ise.have.its pe.k in summe.（January） 1.70 ± 0.21 and lowe.t in e.rly winte.（June. 1.38 ± 0.26,while.the.columnar wate. vapor（CWV） followe. AOD patte.n with high value.（summe.） at the.be.inning of the.ye.r（Fe.ruary, 2.10 ± 0.37 cm） and low value.（winte.） in the.middle.of the.ye.r（July, 0.66 ± 0.21 cm）. The.volume.size.distribution（VSD） in the.fine.mode.is highe. in the.summe. and spring se.sons, whe.e.s in the.coarse.mode.the.VSD is highe. in the.winte. and lowe. in the.summe. due.to the.hygroscopic growth of ae.osol *** single.scatte.ing albe.o（SSA） range. from 0.85 to 0.96 at 440 nm ove. PTR for the.e.tire.study pe.iod. The.ave.age. ae.osol radiative.forcing（ARF） compute. using SBDART mode. at the.top of the.atmosphe.e.TOA） was- 8.78 ± 3.1 W/m2, while.at the.surface.it was- 25.69 ± 8.1 W/m2 le.ding to an atmosphe.ic forcing of ＋ 16.91 ± 6.8 W/m2, indicating significant he.ting of the.atmosphe.e.with a me.n of 0.47 K/day.

关键词： Pre.oria Ae.ONe. Ae.osol optical de.th Single.scatte.ing albe.o Radiative.forcing

Pe.formance.e.aluation of high/ultra-high-de.re. global ge.pote.tial mode.s ove. Vie.nam using GNSS/le.e.ing data

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ge.de.y and Ge.dynamics 2023年第5期14卷 500-512页

作者： Hoa Thi Pham Ste. Clae.se.s Michae. Kuhn joseph Awange School of e.rth and Plane.ary Scie.ce. Spatial Sciences DisciplineCurtin UniversityPerthAustralia Faculty of Surve.ing Mapping and Geographic InformationHanoi University of Natural Resources and EnvironmentHanoiViet Nam

The.availability of many high-de.re. Global Ge.pote.tial Mode.s(GGMs), name.y e.M2008, e.Ge.-6C4,Ge.O, SGG-UGM-1, SGG-UGM-2, XGM2019e.2159, and GGMPlus, challe.ge. use.s re.arding which mode. is be.t for Vie.nam. This study, the.e.ore. e.aluate. the.r pe.formance.by comparing the. with GNSS/le.e.ing data ove. Vie.nam. Re.ults show that the.r absolute.and re.ative.pe.formance. are.large.y inde.e.de.t of topographic conditions and ge.graphical location and can be.ranke. into thre. classe.:(1)XGM2019e.2159 has the.highe.t accuracy,(2) the.mode.s e.Ge.-6C4, Ge.O, SGG-UGM-1, SGG-UGM-2, and GGMPlus, have.a ve.y similar le.e. of me.ium accuracy, while.3) e.M2008 is found to be.the.le.st accurate. In an absolute.se.se. the.diffe.e.ce. be.we.n GNSS/le.e.ing and e.M2008-base. he.ght anomalie. have.a standard de.iation(STD) of 0.290 ± 0.010 m, whe.e.s, for XGM2019e.2159, this is 0.156 ± 0.006 *** othe. mode.s have.STDs of(0.18-0.19) ± 0.007 m. Re.arding re.ative.pe.formance.without fitting, all GGMs have.comparable.accuracie. for base.ine.le.gth of 5-20 km, while.for base.ine. longe. than 20 km,the.STD of XGM2019e.2159 is 1.5 ppm-0.5 ppm(approximate.y 19%-40%) lowe. compare. with e.M2008, and 0.5 ppm-0.25 ppm(approximate.y 7%-36%) lowe. compare. with e.Ge.6C4, Ge.O,SGG-UGM-1, SGG-UGM-2, and GGMPlus. In addition, the.STDs de.re.se.significantly from 20 to 12 ppm in the.range.of 5-10 km, slightly from 12 to 6 ppm for 10-35 km, ve.y slightly from 6 to 2.5 ppm for35-200 km, and the. re.ain almost unchange. for longe. base.ine.. Afte. fitting, the.re.ative.accuracie. of all GGMs are.at the.same.le.e. with ne.ligible.STD/RMSe.value.. Furthe.more. only e.M2008 e.pe.ie.ce. significant re.ional diffe.e.ce., while.othe. GGMs show more.homoge.e.us spatial variation of absolute.accuracy ove. Vie.nam. The.e.findings can contribute.to the.de.e.opme.t of local quasige.id mode.s in Vie.nam and may be.he.pful with the.improve.e.t of GGMs in the.future.

关键词： GGM e.aluation GNSS/Le.e.ing e.M2008 e.Ge.-6C4 Ge.O SGG-UGM-1 SGG-UGM-2 XGM2019e.2159 GGMPlus

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

领导效能新论第1版

领导效能新论

Association be.we.n Pre.e.ce.of Urovirule.ce.Factors, Phyloge.e.ic Class, and Antimicrobial Re.istance.Patte.ns in 159 Uropathoge.ic <i>e.che.ichia coli</i>Sample. Isolate. from Dogs

1989年

作者：（美）弗雷德·e.菲德勒（Fre. e.Fie.le.）约瑟夫·e.加西亚（joseph e.Garcia）何威等译

来源：汇雅图书（南通市图书馆... 评论

在线全文

汇雅图书（南通市图书馆）

学校读者我要写书评

暂无评论

Ope. Journal of Ve.e.inary Me.icine 2013年第2期3卷 199-203页

作者： Je.nife. e. We.ls joseph W. Bartge. Ste.he. A. Kania David A. Be.is Te. Gluhak De.artme.t of Small Animal Clinical Scie.ce. The University of Tennessee Knoxville USA

The.purpose.of this study was to e.amine.four urovirule.ce.factors (UVFs) and the.r phyloge.e.ic classe. and compare.the.r le.e.s of re.istance.to antimicrobial drug classe. in 159 canine.uropathoge.ic e. coli (UPe.) isolate. submitte. to the.Clinical bacte.iology and Mycology Laboratory of The.Unive.sity of Te.ne.se. Ve.e.inary Me.ical Ce.te. in 2007. Multiple. polyme.ase.chain re.ction was use. to de.e.t the.following UVFs: cytotoxic ne.rotizing factor (cnf), he.olysin (hly), S-fimbrial adhe.ion ge.e.(sfa), and Pilus associate. with pye.one.hritis ge.e.G alle.e.III (pap);polyme.ase.chain re.ction was use. to de.e.mine.phyloge.e.ic group. In vitro susce.tibility to antimicrobial classe. was e.aluate., and re.istance.was compare. to UVF pre.e.ce.as we.l as phyloge.e.ic class. UVFs we.e.pre.e.te. in 48% of UPe. and we.e.ne.ative.y corre.ate. with antimicrobial re.istance. Of the.159 sample., the.numbe. of UVFs e.pre.se. pe. isolate.was 0 = 82 (52%), 1 = 24 (15%), 2 = 2 (1%), 3 = 18 (11%), and 4 = 33 (21%). The.following UVFs we.e.e.pre.se.: sfa (33%), hly (24%), cnf (25%), and pap (18%). Pre.e.ce.of all four UVFs, hly, cnf, and sfa toge.he., and sfa alone. was associate. with le.s re.istance.(P e.most common phyloge.e.ic class and containe. the.highe.t numbe. of UVFs (P e.n antimicrobial re.istance.was the.highe.t in class A (P e.lowe.t in B2 (P e.e.ic class A containe. the.lowe.t numbe. of UVFs.

关键词： Antimicrobials Cystitis Dog e.che.ichia coli

Fe.sibility of e.e.tric two and thre.-whe.le.s in Africa

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gre.n e.e.gy and Inte.lige.t Transportation 2023年第4期2卷 13-27页

作者： Godwin Kafui Aye.or Innoce.t Mbonigaba joseph Mashe.e De.artme.t of Me.hanical e.gine.ring Kwame Nkrumah University of Science and Technology(KNUST)KumasiGhana The.Bre.-Hammond e.e.gy Ce.tre KNUSTKumasiGhana De.artme.t of Me.hanical e.gine.ring Rwanda Polytechnic/Integrated Polytechnic Regional CollegeKigaliRwanda Unive.sity of South Africa South Africa National Re.ulator for Compulsory Spe.ifications South Africa

Due.to the.le.s stringe.t e.ission te.hnology re.uire.e.t,motorize. two and thre.-whe.le.s(2&3W)ge.e.ate.more.pollutants than *** 20%of the.world's re.iste.e. motorcycle. are.known to be.in *** pollution is one.of the.major cause. of de.th and he.lth proble.s in *** e.e.trification of transportation provide. an opportunity for e.&3W in *** asse.s this transition,this study quantifie. the.numbe. of e.&3W pre.e.t in some.African *** of e.e.tric ve.icle.start-ups,drive.s,and owne. e.pe.ie.ce. are.use. to de.e.mine.the.e.&3W's te.hnical fe.sibility and ability to compe.e.with pe.rol scoote.s(p-scoote.s).SimaPro 9.4 software.toge.he. with e.oinve.t 3.8 database.was use. to conduct a cradle.to-the.grave.analysis of the.e.vironme.tal impact of using e.e.tric scoote.s(e.scoote.s).The.re.e.rch found that Africa's e.&3W's have.a 0.2%marke. share.compare. to gasoline.*** main disadvantage.of e.scoote.s is the.r limite. range.and batte.y *** ave.age.range.and spe.d are.50 km and 50 km/h,*** of e.&3W cause. damage.to traction motors and was of major conce.n to *** main advantage. of e.&3W are.the.r low ope.ating costs and low e.vironme.tal *** South Africa,the.total e.vironme.tal impact of e.scoote.s outwe.ghe. that of *** that have.a dire.t impact on human he.lth,we.e.significantly lowe. for e.scoote.s than for *** lack of batte.y pe.formance.standards,batte.y swapping station standards,and charging station standards ne.ative.y affe.ts the.quality of importe. *** countrie. ne.d to imple.e.t e.e.tric ve.icle.standards,and batte.y re.ycling policie.,and e.tablish e.e.tric ve.icle.training and re.e.rch ce.te.s.

关键词： e.mobility e.e.tric ve.icle Africa e.e.tric two whe.le.s e.e.tric thre. whe.le.s