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An efficient Boron Source Activation Strategy for the Low‑Temperature Synthesis of Boron Nitride Nanotubes

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Nano-Micro Letters 2025年第1期17卷 548-558页

作者： Ying Wang Kai Zhang Liping Ding Liyun Wu Songfeng e Qian He Nanyang Wang Hui Zuo Zhengyang Zhou Feng Ding Yue Hu Jin Zhang Yagang Yao National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional Materialsand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093People’s Republic of China School of electronic Information and Artificial Intelligence Shaanxi University of Science&TechnologyXian 710000People’s Republic of China College of Bioresources Chemical and Materials engineering Shaanxi University of Science&TechnologyXian 710000People’s Republic of China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325000People’s Republic of China Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518000People’s Republic of China College of Chemical and Molecular engineering Peking UniversityBeijing 100871People’s Republic of China

Lowering the synthesis temperature of boron nitride nanotubes(BNNTs)is crucial for their *** primary reason for adopting a high temperature is to enable the effective activation of highmelting-point solid *** this study,we developed a novel approach for efficiently activating boron by introducing alkali metal compounds into the conventional MgO–B *** approach can be adopted to form various low-melting-point AM–Mg–B–O growth *** growth systems have improved catalytic capability and reactivity even under low-temperature conditions,facilitating the synthesis of BNNTs at temperatures as low as 850℃.In addition,molecular dynamics simulations based on density functional theory theoretically demonstrate that the systems maintain a liquid state at low temperatures and interact with N atoms to form BN *** findings offer novel insights into the design of boron activation and are expected to facilitate research on the low-temperature synthesis of BNNTs.

关键词： Boron nitride nanotubes Low-temperature Boron activation Density functional theory

Therapeutic potential of exercise-hormone irisin in Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1555-1564页

作者： eunhee Kim Rudolph eTanzi Se Hoon Choi Genetics and Aging Research Unit MassGeneral Institute for Neurodegenerative DiseaseDepartment of NeurologyMassachusetts General HospitalHarvard Medical SchoolCharlestownMAUSA McCance Center for Brain Health Massachusetts General HospitalBostonMAUSA

Irisin is a myokine that is generated by cleavage of the membrane protein fibronectin type Ⅲ domain-containing protein 5(FNDC5) in response to physical exercise. Studies reveal that irisin/FNDC5 has neuroprotective functions against Alzheimer's disease, the most common form of dementia in the elderly, by improving cognitive function and reducing amyloid-β and tau pathologies as well as neuroinflammation in cell culture or animal models of Alzheimer's disease. Although current and ongoing studies on irisin/FNDC5 show promising results, further mechanistic studies are required to clarify its potential as a meaningful therapeutic target for alleviating Alzheimer's disease. We recently found that irisin treatment reduces amyloid-β pathology by increasing the activity/levels of amyloid-β-degrading enzyme neprilysin secreted from astrocytes. Herein, we present an overview of irisin/FNDC5's protective roles and mechanisms against Alzheimer's disease.

关键词： Alzheimer's disease exercise fibronectin typeⅢdomain-containing protein 5(FNDC5) irisin

CHARACTeRIZATION OF eFFICIeNT SOLUTIONS FOR MULTI-OBJeCTIVe OPTIMIZATION PROBLeMS INVOLVING SeMI-STRONG AND GeNeRALIZeD SeMI-STRONG e-CONVeXITY

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Acta Mathematica Scientia 2008年第1期28卷 7-16页

作者： e.A.Youness Tarek emam Department of Mathematics Faculty of ScienceTanta UniversityTantaEgypt Department of Mathematics Faculty of Education in SuezSuez Canal UniversitySuezEgypt

The authors of this article are interested in characterization of efficient solutions for special classes of problems. These classes consider semi-strong e-convexity of involved functions. Sufficient and necessary con... 详细信息

关键词： Multi-objective optimization problems semi-strong e-convex efficient solutions properly efficient solutions

RATIO OF CHARMeD BARYON TO MeSON IN e^(+)e^(-) ANNIHILATION

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Chinese Physics Letters 1990年第3期7卷 109-112页

作者： CHeN e-sheng WU Qian Department of Physics Shandong UniversityJinan 250100

A method to determine the value of the ratio of charmed baryon to meson in e^(+)e^(-) annihilation is *** the data of CLeO,HRS and MARK Ⅱ groups,we obtain f≡B_(c)/M_(c)=0.21±0.05,0.24±0.08 and 0.33±0.05,for √s=5... 详细信息

关键词： annihilation meson charm

e]iomimetic approaches toward smart bio-hybric systems

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Nano Research 2018年第6期11卷 3009-3030页

作者： Zhiqiang Luo Dara e. Weiss Qingyun Liu Bozhi Tian Colleae of Life Science and Technology Huazhong University of Science and Technology Wuhan 430074 China Department of Chemistry The University of Chicago Chicago IL 606d7 USA The James Franck Institute The University of Chicago Chicago IL 60637 USA The Institute for Biophysical Dynamics The University of Chicago Chicago IL 60637 USA

Bio-integrated materials and devices can blur the interfaces between living and artificial systems. Microfluidics, bioelectronics, and engineered nanostructures, with close interactions with biology at the cellular or tissue levels, have already yielded a spectrum of new applications. Many new designs emerge, including of organ-on-a-chip systems, biodegradable implants, electroceutical devices, minimally invasive neuro-prosthetic tools, and soft robotics. In this review, we highlight a few recent advances of the fabrication and application of smart bio-hybrid systems, with a particular emphasis on the three-dimensional （3D） bio-integrated devices that mimic the 3D feature of tissue scaffolds. Moreover, neurons integrated with engineered nanostructures for wireless neuromodulation and dynamic neural output are briefly discussed. We also discuss the progress in the construction of cell-enabled soft robotics, where a tight coupling of the synthetic and biological parts is crucial for efficient function. Finally, we summarize the approaches for enhancing bio-integration with biomimetic micro- and nanostructures.

关键词： bio-integrated device bio-hybrid system biomimetics nano-bio interface

A pharmacologist's journey in medical education:a personal history

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Acta Pharmacologica Sinica 2004年第9期25卷 102-106页

作者： e e DANIeL AB T6G 2H7 Canada Department of Pharmacology Room 9-10 edmonton MSB University of Alberta

My journey as an educator in Pharmacology began in 1949, when, after finishing my MA in Biology at Johns Hopkins, Ⅰ decided that Ⅰ wanted to be involved in science with more relevance to humans. Ⅰhad been chasing f... 详细信息

关键词： ACe A pharmacologist’s journey in medical education

The Flora of Siahrud-e Rudbar Protected Area,Northern Iran

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植物分类与资源学报 2015年第5期37卷 572-576页

作者： Ataei-e jaliseh Somayeh Department of Biology Rasht BranchIslamic Azad University

The vascular flora of the Siahrud-e Rudbar protected area was investigated in the years 2007 and 2008. It is a sylvatic area in the Guilan province with a total area of approximately 28 289 hectares. A total of 711 plant specimens were collected and 616 species,subspecies,and varieties,belonging to 373 genera and 101 families were identified. Of these,14 species( 2. 3%) are endemic to Iran. The documented flora exhibited many typically Hyrcanian species,including Hyrcanian endemics. The global phytogeographical affinities of the species were as follows:euro-Siberian 21. 2%,Iran-Turanian & euro-Siberian 16. 8%,Pluriregional 11. 7%,Iran-Turanian 10. 6%,and Cosmopolite 5. 5%.

关键词：竹亚科宁南方竹香竹云南龙竹果实形态

Validation of CFD-DeM model for iron ore reduction at particle level and parametric study

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Particuology 2020年第4期18卷 163-172页

作者： Dianyu e International Research Institute for Minerals Metallurgy and MaterialsJiangxi University of Science and TechnologyNanchang 330013China Department of Chemical engineering Monash UniversityClaytonVIC 3800Australia

Iron ore reduction is a primary unit operation in current metallurgy processes and dominates the energy consumption and greenhouse gas(GHG)emissions of the iron-making process,Therefore,even a slight improvement of the energy efficiency or GHG emissions of iron ore reduction would yield considerable benefits to the cost of pig iron and,more importantly,to mitigation of the associated carbon *** current study presents a discrete model that describes the iron ore reduction process for a single *** transient reaction progress can be predicted and is validated against experimental measurements under various operating conditions,including different reducing gases and *** effects of pressure,isothermality,gas composition,and flow rate on reduction are *** reduction rate increases significantly with increasing pressure until 5 atm,and the entire reduction process occurs more slowly under non-isothermal conditions than under isothermal *** work provides a solid foundation for the development of a comprehensive particulate system model that considers both heat and mass transfer.

关键词： Iron ore reduction Chemical reaction Blast furnace Discrete element method Computational fluid dynamics

Human papillomavirus 16 e6 is associated with the nuclear matrix of esophageal carcinoma cells

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World Journal of Gastroenterology 2001年第6期7卷 788-791页

作者： S.B.Cheng e.C.Chew Department of Physiology and The Chinese University of Hong Kong ShatinNT.Hong KongChina Department of Anatomy The Chinese University of Hong KongShatinNT.Hong KongChina

AIM: To explore the etiologic role of HPV infection in esophageal carcinoma, and the association of HPV-16 e6with the nuclear metrix of carcinoma cells.MeTHODS: Two esophageal carcinoma cell lines, eC/CUHK1 and eC/CUHK2, were tested for HPV-16 e6subgenetic fragment by polymerase chain reaction amplification of virus DNA associated nuclear matrix. RT-PCR and immunocytochemistry were also used to visualizethe expression of e6 subgene in the cells.ReSULTS: The HPV-16 e6 subgenetic fragment wes found to be present in nuclear metrix-associeted DNA, e6oncoprotein localized in the nucleus where it is tightly associated with nuclear matrix after sequential extraction in eC/CUHK2 cells. It was not detected, however, in eC/CUHK1 cells.CONCLUSION: The interaction between HPV-16 e6 and nuclear matrix may contribute to the virus induced carcinogenesis in esophageal carcinoma.

关键词： esophageal neoplasms/virology esophaheal neoplasms/pathology Tumor cells, cultured Papillomavirus, human Nuclear matrix