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Antioxidant efficiency of lycopene on oxidative stress-induced damage in bovine spermatozoa

Journal of Animal Science and Biotechnology 2017年第1期8卷 67-79页

作者： Eva Tvrdá Anton Kovácik Eva Tusimová dusan paál Alica Mackovich Jakhongir Alimov Norbert lukác Department of Animal Physiology Faculty of Biotechnology and Food Sciences Slovak University of Agriculture in Nitra Tr. A. Hlinku 2 Nitra 94976 Slovakia AgroBioTech Research Centre Slovak University of Agriculture in Nitra Tr. A. Hlinku 2 Nitra 94976 Slovakia Department of Botany and Genetics Faculty of Natural Sciences Constantine the Philosopher University in Nitra Nabbrezie mladeze 91 Nitra 94974 Slovakia Department of General Biology Faculty of Natural Sciences Gulistan State University 4th Microrayon Guliston 120100 Syrdarya Uzbekistan.

Background： lycopene（lYC） is a natural carotenoid with powerful reactive oxygen species（ROS） scavenging activities. The aim of this study was to investigate if lycopene has the ability to reverse ROS-mediated alterations to the motility, viability and intracellular antioxidant profile of bovine spermatozoa subjected to ferrous ascorbate（Fe AA）. Spermatozoa were washed out of fresh bovine semen, suspended in 2.9 % sodium citrate and subjected to lYC treatment（0.25, 0.5, 1 or 2 mmol/l） in the presence or absence of Fe AA（150 μmol/l Fe SO4 and 750 μmol/l ascorbic acid） during a 6 h in vitro culture. Spermatozoa motion characteristics were assessed using the Sperm Vision？computer-aided sperm analysis（CASA） system. Cell viability was examined with the metabolic activity（MTT） assay,ROS generation was quantified via luminometry and the nitroblue-tetrazolium（NBT） test was applied to quantify the intracellular superoxide formation. Cell lysates were prepared at the end of the in vitro culture to investigate the intracellular activity of superoxide dismutase（SOD）, catalase（CAT）, glutathione peroxidase（GPx） as well as the concentrations of glutathione（GSH） and malondialdehyde（MDA）.Results： FeA A treatment led to a reduced spermatozoa motility（P 〈 0.001）, viability（P 〈 0.001） and a decline of the antioxidant capacity of spermatozoa（P 〈 0.001） but increased the ROS generation（P 〈 0.001）, superoxide production（P 〈 0.001） and lipid peroxidation（P 〈 0.001）. lYC administration resulted in a preservation of the spermatozoa motion parameters（P 〈 0.001）, mitochondrial activity（P 〈 0.001） and antioxidant characteristics（P 〈 0.001 with respect to SOD;P 〈 0.01 in relation to CAT; P 〈 0.05 as for GPx and GSH） with a concentration range of 1 and 2 mmol/l lYC revealed to be the most ***： Our results suggest that lYC exhibits significant ROS-scavenging and antioxidant properties which may prevent spermatozoa alterations caused by oxidative stress, and preserve the functional

关键词： Antioxidants Bulls Ferrous ascorbate lycopene Oxidative stress Spermatozoa

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Natural high-porous diatomaceous-earth based self-floating aerogel for efficient solar steam power generation

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Green Energy & Environment 2024年第2期9卷 378-389页

作者： Aitang Zhang Kai Wang Md Julker Nine Mengyu Cao Hanwen Zong Zhiqiang liu Hanwen Guo Jingquan liu dusan losic College of Materials Science and Engineering Institute for Graphene Applied Technology InnovationCollaborative Innovation Center for Marine Biomass Fibers Materials and Textiles of Shandong ProvinceQingdao UniversityQingdao266071China The University of Adelaide School of Chemical Engineering and Advanced MaterialsARC Graphene Research HubNorth Engineering BuildingN206 AdelaideSA 5005Australia

The application of solar steam generation in seawater desalination is an effective way to solve the shortage of fresh water *** present,many kinds of photothermal conversion materials have been developed and used as evaporators in seawater ***,some evaporators need additional thermal insulation or water supply devices to achieve efficient photothermal *** addition,their complex,time consuming and no scalable preparation process,high cost of raw materials and poor salt resistance hinder the practical application of these *** to its distinctive nanoporous structure,diatomite as fossilized single-cells algae diatoms is a promising natural silica-based material for seawater *** are taken from sea and that makes true sense to use them in the ***,we report the first example of synthesis robust three-dimensional(3D)natural-diatomite composite by assembling polyaniline nanoparticles covered diatomite into the polyvinyl alcohol pre-treated melamine foam frameworks and demonstrate its application as new evaporator for seawater *** porous framework does not only improve the sunlight scattering efficiency,but also offer large network of channels for water *** inherent mechanism behind salt desalination process involves the absorption of water molecules on the surface of the internal silica micro-nano pores,and evaporation under the heat induced by the polyaniline absorbed ***,the metal ions are segregated by many available pores and channels to achieve the self-desalting *** developed evaporator possesses the superiority of multi-stage pore structure,strong hydrophilicity,low thermal conductivity,excellent light absorption,fast water transportation and salt-resistant crystallization as well as good *** evaporation rate without an additional device is found to be 1.689 kg m^(-2)h^(-1)under 1-Sun irradiation,and the energy conversion efficiency is as

关键词： Diatomite Micro/nanopores Polyaniline Three-dimensional composite Solar steam generation

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Constipation and colonoscopy

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World Journal of Gastrointestinal Endoscopy 2024年第5期16卷 244-249页

作者： dusan Dj Popovic Branka Filipovic Faculty of Medicine University of BelgradeBelgrade 11000Serbia Department of Gastroenterology and Hepatology Clinic for Internal MedicineUniversity Clinical Hospital Center“Dr.Dragisa Misovic-Dedinje”Belgrade 11000Serbia

Constipation is a significant sociomedical problem,which can be caused by various *** the diagnostic approach to patients with constipation,the following data are usually sufficient:History,complete physical examination(including rectal examination),and additional diagnostic tests.A colonoscopy is not a necessary diagnostic method for all patients with ***,if patients have alarm symptoms/signs,that suggest an organic reason for constipation,a colonoscopy is *** most important alarm symptoms/signs are age>50 years,gastrointestinal bleeding,new-onset constipation,a palpable mass in the abdomen and rectum,weight loss,anemia,inflammatory bowel disease,and family history positive for colorectal *** endoscopists do not like to deal with patients with *** are two reasons for this,namely the difficulty of endoscopy and the adequacy of *** are adversely affected by *** improve the quality of colonoscopy in these patients,good examination techniques and often more extensive preparation are *** colonoscopy technique implies adequate psychological preparation of the patient,careful insertion of the endoscope with minimal insufflation,and early detection and resolution of *** preparation for colonoscopy often requires prolonged preparation and sometimes the addition of other laxatives.

关键词： Constipation Functional constipation Colonoscopy Bowel preparation Polyethylene glycol

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Fast and scalable routing protocols for data center networks

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Digital Communications and Networks 2023年第6期9卷 1340-1350页

作者： Mihailo Vesovic Aleksandra Smiljanic dusan Kostic School of Electrical Engineering University of Belgrade11120BelgradeSerbia Amazon Web Services(AWS) ZurichSwitzerland

Data center networks may comprise tens or hundreds of thousands of nodes,and,naturally,suffer from frequent software and hardware failures as well as link *** are routed along the shortest paths with sufficient resources to facilitate efficient network utilization and minimize *** such dynamic networks,links frequently fail or get congested,making the recalculation of the shortest paths a computationally intensive *** routing protocols were proposed to overcome this problem by focusing on network utilization rather than ***,the design of fast shortest-path algorithms for data centers was largely neglected,though they are universal components of routing ***,parallelization techniques were mostly deployed for random network topologies,and not for regular topologies that are often found in data *** aim of this paper is to improve scalability and reduce the time required for the shortest-path calculation in data center networks by parallelization on general-purpose *** propose a novel algorithm that parallelizes edge relaxations as a faster and more scalable solution for popular data center topologies.

关键词： Routing protocols Data center networks parallel algorithms Distributed algorithms Algorithm design and analysis Shortest-path problem Scalability

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On Some Novel Fixed Point Results for Generalized F-Contractions in b-Metric-like Spaces with Application

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Computer Modeling in Engineering & Sciences 2023年第4期135卷 673-686页

作者： Kastriot Zoto Ilir Vardhami dusan Bajovic Zoran D.Mitrovic Stojan Radenovic Department of Mathematics and Computer Sciences Faculty of Natural SciencesUniversity of GjirokastraGjirokastra6001Albania Department of Mathematics Faculty of Natural SciencesUniversity of TiranaTirana1001Albania Faculty of Electrical Engineering University of Banja LukaBanja Luka78000Bosnia and Herzegovina Department of Mathematics Faculty of Mechanical EngineeringUniversity of BelgradeBeograd11120Serbia

The focusofourwork is on themost recent results infixedpoint theoryrelated *** variants of(s,q,φ,F)-contractions that expand,supplement and unify an important work widely discussed in the literature,based on existing classes of interpolative and *** particular,a large class of contractions in terms of s,q,φand F for both linear and nonlinear contractions are defined in the framework of b-metric-like *** main result in our paper is that(s,q,φ,F)-g-weak contractions have a fixed point in b-metric-like spaces if function F or the specified contraction is *** an application of our results,we have shown the existence and uniqueness of solutions of some classes of nonlinear integral equations.

关键词： (φ,F)-contraction (s,q,φ,F)-contraction b-metric-like space fixed point

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Gallium containing bioactive materials: A review of anticancer, antibacterial, and osteogenic properties

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Bioactive Materials 2022年第11期7卷 125-146页

作者： Fatih Kurtuldu Nurshen Mutlu Aldo R.Boccaccini dusan Galusek FunGlass Alexander Dubcek University of TrencínStudentska 291150TrencínSlovakia Institute of Biomaterials Department of Material Science and EngineeringUniversity of Erlangen-Nuremberg91058ErlangenGermany Joint Glass Centre of the IIC SAS TnUAD and FChFT STUStudentska 291150TrencínSlovakia

The incorporation of gallium into bioactive materials has been reported to enhance osteogenesis,to influence blood clotting,and to induce anti-cancer and anti-bacterial ***-doped biomaterials prepared by various techniques include melt-derived and sol-gel-derived bioactive glasses,calcium phosphate bioceramics,metals and *** this review,we summarize the recently reported developments in antibacterial,anti-cancer,osteogenesis,and hemostasis properties of Ga-doped biomaterials and briefly outline the mechanisms leading to Ga biological *** key finding is that gallium addition to biomaterials has great potential for treating bone-related diseases since it can be efficiently transferred to the desired region at a controllable ***,it can be used as a potential substitute for antibiotics for the inhibition of infections during the initial and advanced phases of the wound healing *** is also used as an anticancer agent due to the increased concentration of gallium around excessive cell proliferation(tumor)***,we highlight the possibility to design different therapeutic approaches aimed at increasing the efficiency of the use of gallium containing bioactive materials for multifunctional applications.

关键词： Antibacterial Bioactive materials Cancer treatment Hemostasis Osteogenesis

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3D printing interface-modified PDMS/MXene nanocomposites for stretchable conductors

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Journal of Materials Science & Technology 2022年第22期117卷 174-182页

作者： Mathias Aakyiir Brayden Tanner Pei lay Yap Hadi Rastin Tran Thanh Tung dusan losic Qingshi Meng Jun Ma UniSA STEM and Future Industries Institute University of South AustraliaSouth Australia 5095Australia ARC Hub for Graphene Enabled Industry Transformation School of Chemical Engineering and Advanced MaterialsThe University of AdelaideAdelaideSouth Australia 5005Australia Commonwealth Scientific and Industrial Research Organisation(CSIRO)Manufacturing ClaytonVictoria 3168Australia College of Aerospace Engineering Shenyang Aerospace UniversityShenyangLiaoning 110136China

Additive manufacturing has rapidly evolved over recent years with the advent of polymer inks and those inks containing novel *** compatibility of polymer inks with nanomaterial inks remains a great *** yet effective methods for interface improvement are highly sought-after to significantly enhance the functional and mechanical properties of printed polymer *** this study,we developed and modified a Ti_(3)C_(2) MXene ink with a siloxane surfactant to provide compatibility with a polydimethylsiloxane(PDMS)*** rheology of all the inks was investigated with parameters such as complex modulus and viscosity,confirming a self-supporting ink behaviour,whilst Fourier transform infrared spectroscopy exposed the inks’reaction *** modified MXene nanosheets have displayed strong interactions with PDMS over a wide strain *** electrical conductivity of 6.14×10^(−2) S cm^(−1) was recorded for a stretchable nanocomposite conductor containing the modified MXene *** nanocomposite revealed a nearly linear stress-strain relationship and a maximum stress of 0.25 *** 5%strain,the relative resistance change remained below 35%for up to 100 cycles,suggesting high flexibility,conductivity and mechanical *** study creates a pathway for 3D printing conductive polymer/nanomaterial inks for multifunctional applications such as stretchable electronics and sensors.

关键词： 3D printing MXene Nanocomposites Stretchable conductors

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Spontaneous liver rupture following SARS-CoV-2 infection in late pregnancy:A case report

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World Journal of Clinical Cases 2022年第15期10卷 5042-5050页

作者： Radek Ambroz Martin Stasek Ján Molnár Petr Spicka dusan Klos Jozef Hambálek Daniela Skanderová Department of Surgery I University Hospital Olomouc and Faculty of Medicine and DentistryPalacky UniversityOlomouc 77900Czech Republic Department of Obstetrics and Gynecology University Hospital Olomouc and Faculty of Medicine and DentistryPalacky UniversityOlomouc 77900Czech Republic Department of pathology University Hospital Olomouc and Faculty of Medicine and DentistryPalackýUniversityOlomouc 77900Czech Republic

BACKGROUND Coronavirus disease-2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is characterized by systemic inflammatory response syndrome and ***-CoV-2 associated mortality ranges from 2%to 6%.liver dysfunction was observed in 14%-53%of COVID-19 cases,especially in moderate severe ***,no cases of spontaneous hepatic rupture in pregnant women with SARS-CoV-2 have been *** SUMMARY A 32-year-old pregnant patient(gestational age:32 wk+4 d)without any remarkable medical history or long-term medication presented with ***,non-infectious,and pregnancy-related hepatopathies were *** onset of right subcostal pain with D-dimer and liver enzyme elevation was followed by shock with *** performing an emergency cesarean section,hemoperitoneum was observed,and the patient delivered a stillbirth.A 6-cm liver rupture at the edges of segments V and VI had occurred,which was sutured and ***-CoV-2 positivity on reverse transcriptionpolymerase chain reaction was *** revisions for intrahepatic hematoma with hemorrhagic shock and abdominal compartment syndrome were ***,the patient developed hemoptysis,which was treated using bronchoscopic therapy and non-invasive *** tissue biopsy revealed hemorrhagic foci and necrosis with an irregular centrilobular *** syndrome and autoimmune hepatitis were also ruled *** death was caused by acute intrauterine *** This case reveals that pregnant women with SARS-CoV-2 infection may be predisposed to liver parenchyma disease with liver rupture.

关键词： liver rupture SARS-CoV-2 Pregnancy Abortion HEllP Case report

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Gazeau–Klauder coherent states examined from the viewpoint of diagonal ordering operation technique

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Chinese Physics B 2016年第7期25卷 114-123页

作者： dusan Popov Romeo Negrea Miodrag Popov Politehnica University Timisoara Department of Physical Foundations of Engineering 300223 Timisoara Romania Politehnica University of Timisoara Department of Mathematics 300006 Timisoara Romania politehnica University Timisoara Department of Architecture and Urban Planning 300223 Timisoara Romania

In this paper we investigate the Gazeau–Klauder coherent states using a newly introduced diagonal ordering operation technique, in order to examine some of the properties of these coherent states. The results coincide with those obtained from other purely algebraic methods, but the calculations are greatly simplified. We apply the general theory to two cases of Gazeau–Klauder coherent states： pseudoharmonic as well as the Morse oscillators.

关键词： coherent states operator technique density operator

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parameter estimation and reliable fault detection of electric motors

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Control Theory and Technology 2014年第2期12卷 110-121页

作者： dusan PROGOVAC le Yi WANG George YIN Delphi Corporation 3000 University Drive Auburn Hills MI 48326 U.S.A. Department of Electrical and Computer Engineering Wayne State University Detroit MI 48202 U.S.A. Department of Mathematics Wayne State University Detroit MI 48202 U.S.A.

Accurate model identification and fault detection are necessary for reliable motor control. Motor-characterizing parameters experience substantial changes due to aging, motor operating conditions, and faults. Consequently, motor parameters must be estimated accurately and reliably during operation. Based on enhanced model structures of electric motors that accommodate both normal and faulty modes, this paper introduces bias-corrected least-squares （lS） estimation algorithms that incorporate functions for correcting estimation bias, forgetting factors for capturing sudden faults, and recursive structures for efficient real-time implementation. Permanent magnet motors are used as a benchmark type for concrete algorithm development and evaluation. Algorithms are presented, their properties are established, and their accuracy and robustness are evaluated by simulation case studies under both normal operations and inter-turn winding faults. Implementation issues from different motor control schemes are also discussed.

关键词： Electric machine parameter estimation Fault detection Brushless direct current (BlDC) motor Bias correction Forgetting factor

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