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Reviewing Stability Criteria for Positive Homogeneous Systems and Adding One for Discrete-Time Cases with Degree Less Than One

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Circuits and Systems 2024年第1期15卷 1-11页

作者： Nguyen quang tuan Faculty of Information Technology Nha Trang University Khanh Hoa Vietnam

The article synthesizes and presents the results regarding the stability of positive homogeneous systems that have been researched and published in recent years. Next, we provide a sufficient condition for global exponential stability in the case of discrete-time positive homogeneous systems with an order less than one with time-varying delays.

关键词： Exponential Stability Homogeneous Systems Positive Systems Positive Homogeneous Systems

Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical management

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Journal of Pharmaceutical Analysis 2024年第1期14卷 16-38页

作者： Nguyen quang Thu Nguyen Tran Nam Tien Nguyen Thi Hai Yen Thuc-Huy duong Nguyen Phuoc Long Huy Truong Nguyen Department of Pharmacology and PharmacoGenomics Research Center Inje University College of MedicineBusan47392Republic of Korea Department of Chemistry University of EducationHo Chi Minh City700000Viet Nam Faculty of Pharmacy Ton Duc Thang UniversityHo Chi Minh City700000Viet Nam

The spread of tuberculosis(TB),especially multidrug-resistant TB and extensively drug-resistant TB,has strongly motivated the research and development of new anti-TB *** strategies to facilitate drug combinations,including pharmacokinetics-guided dose optimization and toxicology studies of first-and second-line anti-TB drugs have also been introduced and *** chromatography-mass spectrometry(LC-MS)has arguably become the gold standard in the analysis of both endo-and exo-genous *** technique has been applied successfully not only for therapeutic drug monitoring(TDM)but also for pharmacometabolomics *** improves the effectiveness of treatment,reduces adverse drug reactions,and the likelihood of drug resistance development in TB patients by determining dosage regimens that produce concentrations within the therapeutic target *** on TDM,the dose would be optimized individually to achieve favorable *** is essential in generating and validating hypotheses regarding the metabolism of anti-TB drugs,aiding in the discovery of potential biomarkers for TB diagnostics,treatment monitoring,and outcome *** article highlighted the current progresses in TDM of anti-TB drugs based on LC-MS bioassay in the last two ***,we discussed the advantages and disadvantages of this technique in practical *** pressing need for non-invasive sampling approaches and stability studies of anti-TB drugs was ***,we provided perspectives on the prospects of combining LC-MS-based TDM and pharmacometabolomics with other advanced strategies(pharmacometrics,drug and vaccine developments,machine learning/artificial intelligence,among others)to encapsulate in an all-inclusive approach to improve treatment outcomes of TB patients.

关键词： Tuberculosis Therapeutic drug monitoring LC-MS MIPD Pharmacometabolomics Precision medicine

Wedelolactone from Eclipta prostrata(L)*** inflammation and improves insulin resistance

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Asian Pacific Journal of Tropical Biomedicine 2024年第6期14卷 253-258页

作者： Trinh Tat Cuong duong Duc Thien Hoang Hai Yen Nguyen Anh Duc Trinh quang Nam Do Viet Khanh Key Laboratory for Enzyme and Protein Technology Vietnam National University University of ScienceHanoiVietnam Faculty of Biology Vietnam National University University of ScienceHanoiVietnam Hanoi University of Pharmacy HanoiVietnam Vinschool HanoiVietnam

Objective:To evaluate the effects of wedelolactone,a major flavonoid from Vietnamese Eclipta prostrata(L)L.,on inflammation and insulin ***:Wedelolactone was extracted from the leaves of Vietnamese Eclipta prostrata(L.)*** methanol by *** effects of wedelolactone on lipopolysaccharide(LPS)-induced cytokine production,reactive oxygen species(ROS)generation,and nicotinamide adenine dinucleotide phosphate(NADPH)oxidase activities in Raw 264.7 cells were measured by enzyme-linked immunosorbent assay(ELISA),specific immunofluorescent dyes and luminometric analysis,*** addition,its effects on glucose uptake and the protein expression of insulin receptor substrate 1(IRS1)and glucose transporter 4(GLUT4)were examined in 3T3-L1 cells by immunofluorescent dyes and Western ***:Wedelolactone at 30μg/mL significantly inhibited LPS-induced production of tumor necrosis factor-α,interleukin(IL)-6,and IL-8(P<0.01)with no noticeable effects on IL-10 *** also reduced ROS generation and NADPH oxidase activities in LPS-stimulated Raw 264.7 cells(P<0.01).Furthermore,wedelolactone showed anti-insulin resistance activity,as evidenced by improved glucose uptake and the upregulated expression of IRS1 and GLUT4 in 3T3-L1 cells(P<0.01).Conclusions:Wedelolactone exhibits anti-inflammation and anti-insulin resistance effects,which may be used for the treatment of diabetes and inflammation-associated diseases.

关键词： Wedelolactone Eclipta prostrata Inflammatory responses Anti-insulin resistance Diabetes IRS1 GLUT4

Comparison of Treatment Efficacy of Different Number of Botulinum Toxin Type A Injection Sites for Crow’s Feet Lines: A Single-Center Retrospective Clinical Study in Vietnam

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International Journal of Dermatology and Venereology 2024年第3期7卷 131-136页

作者： Minh Nguyen quang Mai Le Thi Hieu duong Phuc Ha Vu Thai Doanh Le Huu Department of Stem Cell Research and Application National Hospital of Dermatology and VenereologyHanoi 100000Vietnam Department of Healthcare Activity Direction National Hospital of Dermatology and VenereologyHanoi 100000Vietnam Department of Dermatology Hanoi Medical UniversityHanoi 100000Vietnam

Objective:Botulinum toxin type A is frequently used to treat crow’s feet ***,the optimal dose and injection sites are still *** objective of this study was to compare the efficacy of different botulinum toxin type A injection patterns for the treatment of crow’s ***:This single-center,retrospective,clinical study was conducted at the National Hospital of Dermatology and Venereology from July 2020 to December *** on 60 patients with crow’s feet were collected and divided into 2 groups(3-or 4-point intramuscular injection)according to the intramuscular injection technique the patients *** treatment efficacy was assessed based on the changes in the Crow’s Feet Grading Scale score at 1,4,and 16 weeks after *** measures analysis of variance was used for the assessment of changes in scores over time between the two ***:After treatment,the average Crow’s Feet Grading Scale score was significantly decreased compared with the pretreatment score at all timepoints(1,4,and 16 weeks)in both states(dynamic:For 3-point intramuscular injection technique,1 week:1.90±0.71 vs.2.97±0.56;4 weeks:1.87±0.68 vs.2.97±0.56;16 weeks:2.60±0.67 vs.2.97±*** 4-point intramuscular injection technique,1 week:1.73±0.83 vs.3.03±0.49;4 weeks:1.73±0.74 vs.3.03±0.49;16 weeks:2.57±0.68 vs.3.03±0.49,all P<*** static:For 3-point intramuscular injection technique,1 week:1.20±0.89 vs.2.20±0.85;4 weeks:1.20±0.89 vs.2.20±0.85;16 weeks:1.87±0.97 vs.2.20±0.85;For 4-point intramuscular injection technique,1 week:1.50±0.86 vs.2.30±0.84;4 weeks:1.33±0.84 vs.2.30±0.84;16 weeks:1.87±0.97 vs.2.30±*** P<0.001).The average subjective patient-rated satisfaction scores after treatment were significantly higher in the 4-point injection group than in the 3-point injection group(P=0.028).The adverse events were post-injection bruising in 3 patients and a feeling of eyelid tightness in 3 ***:Botulinum toxin type A injecti

关键词： botulinum toxin type A crow’s feet lines injection site dose

维普期刊数据库

The topology of foliations formed by the generic K-orbits of a subclass of the indecomposable MD_5-groups

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Science China Mathematics 2009年第2期52卷 351-360页

作者： VU Le Anh HOA duong quang Department of Mathematics and Informations University of Pedagogy Ho Chi Minh CityDistrict 5 Vietnam

The paper is a continuation of the authors' works in 2007. We consider the MD_5-foliations associated to connected and simply connected MD_5-groups such that their Lie algebras have 4-dimensional commutative derived ideals. In this study, we give a topological classification of all considered MD_5-foliations. A description of these foliations by certain fibrations or suitable actions of R2 and the Connes' C*-algebras of the foliations which come from fibrations are also given.

关键词： Lie group Lie algebra MD_5-group MD_5-algebra K-orbits foliation measured foliation

维普期刊数据库

Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study

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贫困所致传染病(英文) 2024年第2期13卷 1-12页

作者： Nguyen Hoa Binh quang Vo Luan Nguyen Forse Rachel Jeanette Wiemers Anja Maria Christine Huynh Huy Ba Dong Thuy Thi Thu Phan Yen Thi Hoang Creswell Jacob Dang Thi Minh Ha Nguyen Lan Huu Shedrawy Jad L?nnroth Knut Nguyen tuan Dinh Van Dinh Luong Annerstedt Kristi Sidney Codlin Andrew James National Lung Hospital Ha Noi Viet Nam Friends for International TB Relief Ha Noi Viet Nam Department of Global Public Health WHO Collaboration Centre On Tuberculosis and Social Medicine Karolinska Institute Stockholm Sweden Stop TB Partnership Geneva Switzerland Pham Ngoc Thach Hospital Ho Chi Minh City Viet Nam

Background In Viet Nam, tuberculosis (TB) represents a devastating life-event with an exorbitant price tag, partly due to lost income from daily directly observed therapy in public sector care. Thus, persons with TB may seek care in the private sector for its flexibility, convenience, and privacy. Our study aimed to measure income changes, costs and catastrophic cost incurrence among TB-affected households in the public and private *** Between October 2020 and March 2022, we conducted 110 longitudinal patient cost interviews, among 50 patients privately treated for TB and 60 TB patients treated by the National TB Program (NTP) in Ha Noi, Hai Phong and Ho Chi Minh City, Viet Nam. Using a local adaptation of the WHO TB patient cost survey tool, participants were interviewed during the intensive phase, continuation phase and post-treatment. We compared income levels, direct and indirect treatment costs, catastrophic costs using Wilcoxon rank-sum and chi-squared tests and associated risk factors between the two cohorts using multivariate *** The pre-treatment median monthly household income was significantly higher in the private sector versus NTP cohort (USD 868 vs USD 578;P=0.010). However, private sector treatment was also significantly costlier (USD 2075 vs USD 1313;P=0.005), driven by direct medical costs which were 4.6 times higher than costs reported by NTP participants (USD 754 vs USD 164;P<0.001). This resulted in no significant difference in catastrophic costs between the two cohorts (Private: 55% vs NTP: 52%;P=0.675). Factors associated with catastrophic cost included being a single-person household [adjusted odds ratio [(aOR=13.71; 95% confidence interval (CI): 1.36–138.14;P=0.026], unemployment during treatment (aOR=10.86; 95%CI: 2.64–44.60;P<0.001) and experiencing TB-related stigma (aOR=37.90; 95%CI: 1.72–831.73;P=0.021).Conclusions Persons with TB in Viet Nam face similarly high risk of catastrophic costs whether treated in the

关键词： Tuberculosis Patient cost Catastrophic cost Private sector Comparative analysis Viet Nam

Effect of Poly-Alkylene-Glycol Quenchant on the Distortion, Hardness, and Microstructure of 65Mn Steel

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Computers, Materials & Continua 2021年第6期67卷 3249-3264页

作者： Thi Xuan Tran Xuan Phuong Nguyen duong Nam Nguyen Dinh Toai Vu Minh quang Chau Osamah Ibrahim Khalaf Anh tuan Hoang Hanoi University of Science and Technology HanoiVietnam Ho Chi Minh City University of Transport Ho Chi Minh CityVietnam Vietnam Maritime University HaiphongVietnam Industrial University of Ho Chi Minh City(IUH) Ho Chi Minh CityVietnam Al-Nahrain Nanorenewable Energy Research Center Al-Nahrain UniversityBaghdadIraq Ho Chi Minh city University of Technology(HUTECH) Ho Chi Minh CityVietnam

Currently,the 65Mn steel is quenched mainly by oil *** though the lower cooling rate of oil compared to water reduces the hardness of steel post quenching,the deforming and cracking of parts are often *** the other hand,the oil media also has the disadvantage of being ammable,creating smoke that adversely affects the *** poly alkylene glycol(PAG)polymer quenchant is commonly used for quenching a variety of steels based on its advantages such as non-ammability and exible cooling rate subjected to varying concentration and stirring *** article examines the effect of PAG polymer quenching solution(with concentrations of 10%and 20%)on deformation,hardness,and microstructure of C-ring samples made of 65Mn ***,the performance of PAG polymer quenchant is also compared with those of two common quenching solutions:Water and *** cooling in water,the C-ring samples had the largest deformation and 2 times higher than the results obtained when a 10%PAG solution was *** particular,similar levels of deformation on the C-ring samples were observed in both cases of 20%PAG solution and oil as the primary quenching ***,the hardness level measured between the sampled parts quenched in the 20%PAG solution appeared to be more uniform than that obtained from the oil-quenched *** study of the microscopic structure of steel by optical microscopy combined with X-ray diffraction showed that the water hardened sample exhibited cracks and comprised of two phases,martensite and retained *** to the results of Electron Back Scattering Diffraction(EBSD)analysis and backscattering electronic image(BSE),the content of austenite residue in the sample when the sample was cooled in PAG 10 and 20%solution was 3.21%and 4.73%,respectively and smaller than the measurements obtained from oil quenching ***,the 65Mn steel is cooled in 20%PAG solution for high hardness and more evenly distributed than when it is q

关键词： Polyethylene glycol electron backscattering diffraction quenching media cooling rate backscattering electronic image

CLS-Miner: efficient and effective closed high-utility itemset mining

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Frontiers of Computer Science 2019年第2期13卷 357-381页

作者： Thu-Lan DAM Kenli LI Philippe FOURNIER-VIGER quang-Huy duong College of Computer Science and Electronic Engineering Hunan University Changsha 410082 China Faculty of Information Technology Hanoi University of Industry Hanoi Vietnam CIC of HPC National University of Defense Technology Changsha 410073 China National Supercomputing Center in Changsha Changsha 410082 China School of Natural Sciences and Humanities Harbin Institute of Technology Shenzhen Graduate School Shenzhen 518055 China Department of Computer Science Norwegian University of Science and Technology Trondheim Norway

High-utility itemset mining (HUIM) is a popular data mining task with applications in numerous domains. However, traditional HUIM algorithms often produce a very large set of high-utility itemsets (HUIs). As a result, analyzing HUIs can be very time consuming for users. Moreover, a large set of HUIs also makes HUIM algorithms less efficient in terms of execution time and memory consumption. To address this problem, closed high-utility itemsets (CHUIs), concise and lossless representations of all HUIs, were proposed recently. Although mining CHUIs is useful and desirable, it remains a computationally expensive task. This is because current algorithms often generate a huge number of candidate itemsets and are unable to prune the search space effectively. In this paper, we address these issues by proposing a novel algorithm called CLS-Miner. The proposed algorithm utilizes the utility-list structure to directly compute the utilities of itemsets without producing candidates. It also introduces three novel strategies to reduce the search space, namely chain-estimated utility co-occurrence pruning, lower branch pruning, and pruning by coverage. Moreover, an effective method for checking whether an itemset is a subset of another itemset is introduced to further reduce the time required for discovering CHUIs. To evaluate the performance of the proposed algorithm and its novel strategies, extensive experiments have been conducted on six benchmark datasets having various characteristics. Results show that the proposed strategies are highly efficient and effective, that the proposed CLS-Miner algorithm outperforms the current state-ofthe- art CHUD and CHUI-Miner algorithms, and that CLSMiner scales linearly.

关键词： utility mining high-utility itemset mining closed itemset mining closed high-utility itemset mining

Thermodynamic Simulation on the Change in Phase for Carburizing Process

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Computers, Materials & Continua 2021年第7期68卷 1129-1145页

作者： Anh tuan Hoang Xuan Phuong Nguyen Osamah Ibrahim Khalaf Thi Xuan Tran Minh quang Chau Thi Minh Hao Dong duong Nam Nguyen Ho Chi Minh city University of Technology(HUTECH) HoVietnam Ho Chi Minh city University of Transport Ho Chi Minh cityVietnam Al-Nahrain University Al-Nahrain Nanorenewable Energy Research CenterBaghdadIraq Hanoi University of Science and Technology HanoiVietnam Industrial University of Ho Chi Minh City(IUH) Ho Chi Minh cityVietnam Vietnam Maritime University HaiphongVietnam

The type of technology used to strengthen the surface structure of machine parts,typically by carbon-permeation,has made a great contribution to the mechanical engineering industry because of its outstanding advantages in corrosion resistance and enhanced mechanical and physical ***,carbon permeation is considered as an optimal method of heat treatment through the diffusion of carbon atoms into the surface of alloy *** study presented research results on the thermodynamic calculation and simulation of the carbon permeability *** Fick’s law,the paper calculated the distribution of carbon concentration in the alloy steel after it is absorbed from the surface into the internal of the *** the SYSWELD software,an analysis was performed on the carbon permeability process to determine the distribution of carbon concentrations in 20CrMo steel that was then followed by a detailed analysis of the microstructure of the sample post the carburizing *** to the calculation results,the surface carbon content was 0.9%and steadily decreased into the *** 3 hours,the depth of the absorbent layer was measured at 0.5 mm for both the cylindrical and cubic *** analyzing the phase,the distribution of martensite phases such as ferrite/pearlite and residual austenite was also determined after the carburizing process.

关键词： Carburizing process 20CrMo steel thermodynamic analysis microstructure formation carbon concentration