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A Natural Catalytic Converter^® for Continuously Inactivating Air and Surface Pathogens with More Effect than Ventilation and Filtration

2005年

作者： duffy Daniel J.

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Open Journal of Applied Sciences 2024年第5期14卷 1353-1363页

作者： Margaret Scarlett Brett duffy CAPT. (Ret.) US Public Health Service Centers for Disease Control and Prevention Atlanta GA United States of America ASHRAE (62.1 Standard Committee) Atlanta GA United States of America

Study Objective: The purpose of the study is to present independent laboratory testing for a novel technology in air and on surfaces. Since 2020, public health goals have focused on improving indoor air quality. This includes protection from airborne pathogens, such as tuberculosis, RSV, SARS-CoV-2, common cold or influenza viruses, measles, and others. Engineering controls are highly effective at reducing hazardous pathogens found in indoor air and from recontamination of surfaces. This occurs from a continuous cycle of settling of small, sustained airborne pathogens, which may become dehumidified, becoming airborne again, carried by room air currents around indoor spaces, then repeating the cycle. Methods: The novel technology utilizes a catalytic process to produce safe levels of hydrogen peroxide gas that are effective in reducing pathogens in the air and on surfaces. Air testing was performed with the MS2 bacteriophage, the test organism for ASHRAE standard 241, and methicillin-Resistant Staphylococcus aureus (MRSA). Surface testing was performed with SARS-COV-2 (Coronavirus COVID-19) and H1N1 (Influenza). Typical ventilation and filtration does not effectively remove disbursed pathogens from the entire facility, due to inconsistent air circulation and surface deposits of pathogens. Results: MS2 was reduced by 99.9%;MRSA was reduced by 99.9%;SARS-CoV-2 was reduced by 99.9%;H1N1 was reduced by 99.9%. Conclusion: This novel catalytic converter reduces a variety of pathogens in the air (99%) and on surfaces (99%), by actively disinfecting with the introduction of gaseous hydrogen peroxide. This active disinfection provides a strong solution for protecting the entire facility and its occupants.

关键词： Pathogen Bacteria Virus Reduction Gaseous Hydrogen Peroxide Disinfection Indoor Air Quality Surface

A review of integrated surface-subsurface numerical hydrological models

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Science China Earth Sciences 2024年第5期67卷 1459-1479页

作者： Lele SHU Hao CHEN Xianhong MENG Yan CHANG Litang HU Wenke WANG Longcang SHU Xuan YU Christopher duffy Yingying YAO Donghai ZHENG Key Laboratory of Cryospheric Science and Frozen Soil Engineering Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China College of Water Sciences Beijing Normal UniversityBeijing 100038China School of Water and Environment Chang’an UniversityXi’an 710064China College of Hydrology and Water Resources Hohai UniversityNanjing 210098China State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China Department of Civil and Environmental Engineering Pennsylvania State UniversityState CollegePA 16801USA Department of Earth and Environmental Science School of Human Settlements and Civil EngineeringXi’an Jiaotong UniversityXi’an 710049China Institute of Tibetan Plateau Research Chinese Academy of SciencesBeijing 100101China

Hydrological modeling,leveraging mathematical formulations to represent the hydrological cycle,is a pivotal tool in representing the spatiotemporal dynamics and distribution patterns inherent in *** models serve a dual purpose:they validate theoretical robustness and applicability via observational data and project future trends,thereby bridging the understanding and prediction of natural *** rapid advancements in computational methodologies and the continuous evolution of observational and experimental techniques,the development of numerical hydrological models based on physicallybased surface-subsurface process coupling have *** in micro-scale conservation principles and physical equations,these models employ numerical techniques to integrate surface and subsurface hydrodynamics,thus replicating the macro-scale hydrological responses of *** hydrological models have emerged as a leading and predominant trend in hydrological modeling due to their explicit representation of physical processes,heightened by their spatiotemporal resolution and reliance on interdisciplinary *** article focuses on the theoretical foundation of surface-subsurface numerical hydrological *** includes a comparative and analytical discussion of leading numerical hydrological models,encompassing model architecture,numerical solution strategies,spatial representation,and coupling ***,this paper contrasts these models with traditional hydrological models,thereby delineating the relative merits,drawbacks,and future directions of numerical hydrological modeling.

关键词： Numerical Hydrological Models Surface-Subsurface Process Coupling Numerical Methods Hydrological Modeling

Implementation and evaluation of Exercise is Medicine in primary care clinics within a large academic health system

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Family Medicine and Community Health 2024年第1期12卷 16-27页

作者： John Kevin Ong Dayao Caroline E L duffy Amalia M Cristiano Gene'Rusty'Kallenberg Sarah E Linke University of California San Diego School of Medicine La JollaCaliforniaUSA Milken Institute of Public Health The George Washington UniversityWashingtonDistrict of ColumbiaUSA The University of Texas Medical Branch at Galveston School of Medicine GalvestonTexasUSA Scripps Family Medicine Residency Scripps Mercy Hospital Chula VistaChula VistaCaliforniaUSA Herbert Wertheim School of Public Health&Human Longevity Science University of California San DiegoLa JollaCaliforniaUSA Department of Family Medicine University of California San DiegoLa JollaCaliforniaUSA Omada Health San FranciscoCaliforniaUSA

Objective Exercise is Medicine(EIM)is a global initiative encouraging healthcare providers to routinely assess and promote physical activity(PA)among *** objective of this study was to evaluate the feasibility,adoption,implementation and effectiveness of EIM from patient,clinician and healthcare staff perspectives using a combination of electronic health record(EHR),survey and interview *** This study used a combination of the Practical Robust Implementation and Sustainability Model(PRISM)and the Learning Evaluation model to implement *** captured from the EHR,including Physical Activity Vital Sign(PAVS)scores,and data collected from qualitative surveys and interviews were used to evaluate the programme’s Reach,Effectiveness,Adoption,Implementation,Maintenance(RE-AIM,which is embedded within PRISM)from provider,staff and patient *** Five primary care clinics within a large academic health *** A total of 24443 patients from all participating clinics had at least one PAVS score during the study period.A total of 17 clinicians completed surveys,and 4 clinicians,8 medical assistants and 9 patients completed *** Implementation fidelity metrics varied widely between components and across clinics but were generally consistent over time,indicating a high degree of programme *** was highest during the first 6 months of the COVID-19 pandemic when most visits were *** PAVS scores increased from 57.7(95%CI:56 to 59.4)to 95.2(95%CI:91.6 to 98.8)min per week at 6 months for patients not meeting PA guidelines at baseline and decreased from 253.84(95%CI:252 to 255.7)to 208.3(95%CI:204.2 to 212.4)min per week at 6 months for patients meeting PA guidelines at *** EIM implementation,clinician-estimated time spent discussing PA with patients increased for 35%of providers and stayed the same for 53%.Conclusion Overall,this study established EIM’s feasibility,adoption,implementation

关键词： routine qualitative completed

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地表-地下过程耦合的数值水文模型综述

中国科学：地球科学 2024年第5期54卷 1484-1505页

作者：舒乐乐陈昊孟宪红常燕胡立堂王文科束龙仓俞烜 Christopher duffy 姚莹莹郑东海中国科学院西北生态环境资源研究院冰冻圈科学与冻土工程重点实验室兰州730000 北京师范大学水科学研究院北京100875 长安大学水利与环境学院西安710054 河海大学水文水资源学院南京210098 中国科学院南京土壤研究所土壤与农业可持续发展国家重点实验室南京210008 Pennsylvania State University State CollegePA 16801USA 西安交通大学地球环境科学系西安710054 中国科学院青藏高原研究所北京100101

水文模型是利用数学公式对水文循环过程的描述,是理解自然界水的时空运动和分布规律的重要工具;它不仅可以利用观测数据来验证理论的可靠性与适宜性,还能预测水文变量未来趋势,实现理解自然与预测自然的目的.随着计算方法的快速发展、... 详细信息

水文模型是利用数学公式对水文循环过程的描述,是理解自然界水的时空运动和分布规律的重要工具;它不仅可以利用观测数据来验证理论的可靠性与适宜性,还能预测水文变量未来趋势,实现理解自然与预测自然的目的.随着计算方法的快速发展、观测与试验手段的持续更新,目前基于物理过程的地表-地下过程耦合的数值水文模型快速发展.这种模型以微观尺度的守恒原理和物理公式为基础,利用数值方法将地表和地下水流进行耦合计算,从而模拟流域尺度水文响应过程.由于其物理过程明确、时空分辨率高且利于学科耦合,数值水文模型已成为水文模型发展的前沿和主流方向之一.本文阐述了地表-地下过程耦合数值水文模型的理论基础,从模型框架、数值求解方法、空间表达和耦合算法等方面对比和分析了当前主流数值水文模型,同时与传统水文模型比较,厘清了数值水文模型的优劣势,探讨了未来数值水文模型发展的方向.

关键词：数值水文模型地表-地下过程耦合数值方法水文模型

Oxidative Stress in Collegiate Cross Country Skiers in Mid- and Post-Seasons

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Journal of Biosciences and Medicines 2024年第5期12卷 99-110页

作者： Scott P. Jerome Kriya L. Dunlap Ava M. Parrish Matthew L. Lowman Emily M. Shipman Lawrence K. duffy Arleigh J. Reynolds Department of Chemistry & Biochemistry University of Alaska Fairbanks Fairbanks AK USA Institute of Arctic Biology University of Alaska Fairbanks Fairbanks AK USA Department of Biology & Wildlife University of Alaska Fairbanks Fairbanks AK USA Department of Veterinary Medicine University of Alaska Fairbanks Fairbanks AK USA

Purpose: The oxidative stress (OS) hypothesis of overtraining syndrome argues that increased production of free radicals through exercise cause muscle fatigue and damage resulting in lower athletic performance. Several studies have investigated OS immediately before and after exercise bouts in a training macrocycle. Our study aimed to compare OS of endurance athletes between a competition macrocycle and the immediate post-season recovery macrocycle. In addition, we aimed to identify athletes who experienced an unexplainable drop in athletic performance during the competition season in order to compare their OS to those who experienced no drop in performance. Methods: Fifteen members of the University of Alaska Fairbanks cross country ski team volunteered for this study. Blood samples were taken in early February (“mid-season”) and late April (“post-season”). Participants completed questionnaires regarding physical activity and athletic performance at the time of the blood draws. Plasma was analyzed for 4-hydroxynonenal (HNE), nitrotyrosine, nitric oxide (NOX), and superoxide dismutase (SOD). Significance was determined by Wilcoxon and Mann-Whitney tests. Results: Participants displayed significantly higher (p Conclusion: Signs of oxidative stress and mitigation during the post-season recovery macrocycle were higher in athletes who reported experiencing a drop in athletic performance during the competition season macrocycle.

关键词： Oxidative Stress 4-Hydroxynonenal Superoxide Dismutase Athletic Performance Training Macrocycle

Introduction to C++ for Financial Engineers : An Object-oriented Approach

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Computer-based Creativity Enhanced Conceptual Design Model for Non-routine Design of Mechanical Systems

丛书名： Wiley finance series

2006年

作者： duffy Daniel J.

ISBN: (纸本)9780470015384;9780470058893

This book introduces the reader to the C++ programming language and how to use it to write applications in quantitative finance (QF) and related areas. No previous knowledge of C or C++ is required -- experience with VBA, Matlab or other programming language is sufficient. The book adopts an incremental approach; starting from basic principles then moving on to advanced complex techniques and then to real-life applications in financial engineering. There are five major parts in the book: C++ fundamentals and object-oriented thinking in QF Advanced object-oriented features such as inheritance and polymorphism Template programming and the Standard Template Library (STL) An introduction to GOF design patterns and their applications in QF Applications The kinds of applications include binomial and trinomial methods, Monte Carlo simulation, advanced trees, partial differential equations and finite difference methods. This book includes a companion website with all source code and many useful C++ classes that you can use in your own applications. Examples, test cases and applications are directly relevant to QF. This book is the perfect companion to Daniel J. duffy''s book Financial Instrument Pricing using C++ (Wiley 2004, 0470855096 / 9780470021620)

关键词： Financial engineering

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Chinese Journal of Mechanical Engineering 2014年第6期27卷 1083-1098页

作者： LI Yutong WANG Yuxin duffy Alex H B Department of Mechanical & Electrical Engineering China University of Petroleum Design Manufacture and Engineering ManagementUniversity of Strathclyde

Computer-based conceptual design for routine design has made great strides, yet non-routine design has not been given due attention, and it is still poorly automated. Considering that the function-behavior-structure（FBS） model is widely used for modeling the conceptual design process, a computer-based creativity enhanced conceptual design model（CECD） for non-routine design of mechanical systems is presented. In the model, the leaf functions in the FBS model are decomposed into and represented with fine-grain basic operation actions（BOA）, and the corresponding BOA set in the function domain is then constructed. Choosing building blocks from the database, and expressing their multiple functions with BOAs, the BOA set in the structure domain is formed. Through rule-based dynamic partition of the BOA set in the function domain, many variants of regenerated functional schemes are generated. For enhancing the capability to introduce new design variables into the conceptual design process, and dig out more innovative physical structure schemes, the indirect function-structure matching strategy based on reconstructing the combined structure schemes is adopted. By adjusting the tightness of the partition rules and the granularity of the divided BOA subsets, and making full use of the main function and secondary functions of each basic structure in the process of reconstructing of the physical structures, new design variables and variants are introduced into the physical structure scheme reconstructing process, and a great number of simpler physical structure schemes to accomplish the overall function organically are figured out. The creativity enhanced conceptual design model presented has a dominant capability in introducing new deign variables in function domain and digging out simpler physical structures to accomplish the overall function, therefore it can be utilized to solve non-routine conceptual design problem.

关键词： conceptual design non-routine design creative enhance model computer-based approach mathematical expression

Monte Carlo Frameworks: Building Customisable High-performance C++ Applications 1

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Investigation of a ship resonance through numerical simulation

丛书名： Wiley Finance 406

2009年

作者： Daniel J. duffy Joerg Kienitz

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Journal of Hydrodynamics 2020年第5期32卷 969-983页

作者： S.S.Kianejad Hossein Enshaei Jonathan duffy Nazanin Ansarifard Australian Maritime College University of TasmaniaLauncestonAustralia

Understanding dynamic stability of a ship on a resonance frequency is important because comparatively smaller external forces and moments generate larger *** roll motion is most susceptible because of smaller restoring *** studies related to the failure modes such as parametric roll and dead ship condition,identified by second generation of intact stability criteria(SGISC)are performed at a resonance ***,the nature of resonance,where the model experiences an incremental roll motion,has not been well *** this study,nonlinear unsteady computational fluid dynamics(CFD)simulations were conducted to investigate the resonance phenomenon using a containership under a sinusoidal roll exciting *** capture the complexity of the phenomenon,simulations were conducted over a range of frequencies to cover the resonance frequency including lower and higher *** addition to the resonance frequency,the phase shift between roll exciting moment and roll angle,as well as the phase difference between acceleration and roll angle,were found to have significant effects on the occurrence of resonance.

关键词： Resonance harmonic excited roll motion natural frequency phase shift phase difference