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18例成人重症水痘临床分析

中国麻风皮肤病杂志 2025年第1期41卷 43-47页

作者：杜清陈红赵玄冉启惠邓超赵本南成都市公共卫生临床医疗中心重症二科四川成都610061 成都市公共卫生临床医疗中心内一科四川成都610061

目的:分析成人重症水痘患者的临床特征,提高对该病的认识。方法:回顾性分析我院重症二科2018年1月至2024年3月收治的18例成人重症水痘患者的临床资料。结果:18例患者中男12例、女6例,平均年龄32.1岁(18~50岁),9例(50.0%)因器官移植、类... 详细信息

目的:分析成人重症水痘患者的临床特征,提高对该病的认识。方法:回顾性分析我院重症二科2018年1月至2024年3月收治的18例成人重症水痘患者的临床资料。结果:18例患者中男12例、女6例,平均年龄32.1岁(18~50岁),9例(50.0%)因器官移植、类风湿关节炎等基础疾病长期使用免疫抑制药物。异常实验室结果主要包括血小板计数降低12例(66.7%)、肝酶升高15例(83.3%)、心肌酶升高18例(100%)、N氨基末端脑钠肽升高15例(83.3%)、D-二聚体升高16例(88.9%)、降钙素原升高14例(77.8%)。6例(33.3%)因治疗效果不佳自动出院(3例)或死亡(3例)。15例(83.3%)合并肺部感染,其中11例合并Ⅰ型呼吸衰竭。结论:成人重症水痘患者以男性居多,死亡率较高。免疫抑制个体是成人重症水痘的高发人群。成人重症水痘合并肺部感染患者Ⅰ型呼吸衰竭发生率高。

关键词：重症水痘成年人水痘-带状疱疹病毒肺炎

Relay-intercropping soybean with maize maintains soil fertility and increases nitrogen recovery efficiency by reducing nitrogen input

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The Crop Journal 2020年第1期8卷 140-152页

作者： qing du Li Zhou Ping Chen Xiaoming Liu Chun Song Feng Yang Xiaochun Wang Weiguo Liu Xin Sun Junbo du Jiang Liu Kai Shu Wenyu Yang Taiwen Yong College of Agronomy Sichuan Agricultural UniversityChengdu 611130SichuanChina College of Environment Sichuan Agricultural UniversityChengdu 611130SichuanChina Sichuan Engineering Research Center for Crop Strip Intercropping System/Key Laboratory of Crop Ecophysiology and Farming System in Southwest Ministry of AgricultureChengdu 611130SichuanChina Yibing Academy of Agricultural Sciences Yibing 644000SichuanChina Shehong Farm Bureau Suining 629200SichuanChina

Optimized nitrogen(N)management can increase N-use efficiency in intercropping ***-nonlegume intercropping systems can reduce N input by exploiting biological N fixation by *** of N utilization can help in dissecting the mechanisms underlying N uptake and utilization in legume-nonlegume intercropping *** experiment was performed with three planting patterns:monoculture maize(MM),monoculture soybean(SS),and maize-soybean relay intercropping(IMS),and three N application levels:zero N(NN),reduced N(RN),and conventional N(CN)to investigate crop N uptake and utilization characteristics.N recovery efficiency and 15N recovery rate of crops were higher under RN than under CN,and those under RN were higher under intercropping than under the corresponding *** with MM,IMS showed a lower soil N-dependent rate(SNDR)in ***,the SNDR of MM rapidly declined from 86.8%in 2012 to 49.4%in 2014,whereas that of IMS declined slowly from 75.4%in 2012 to 69.4%in *** interspecific N competition rate(NCRms)was higher under RN than under CN,and increased *** nodule dry weight and nitrogenase activities were respectively 34.2%and 12.5%higher under intercropping than in monoculture at the beginning seed *** amount(Ndfa)and ratio(%Ndfa)of soybean N2 fixation were significantly greater under IS than under *** conclusion,N fertilizer was more efficiently used under RN than under CN;in particular,the relay intercropping system promoted N fertilizer utilization in comparison with the corresponding *** intercropping system helps to maintain soil fertility because interspecific N competition promotes biological N fixation by soybean by reducing N ***,a maize-soybean relay intercropping system with reduced N application is sustainable and environmentally friendly.

关键词： Maize-soybean relay intercropping Reduced nitrogen Biological nitrogen fixation Nitrogen recovery efficiency Soil nitrogen dependent rate

Early enteral nutrition vs parenteral nutrition following pancreaticoduodenectomy: Experience from a single center

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World Journal of Gastroenterology 2016年第14期22卷 3821-3828页

作者： Jian-Wen Lu Chang Liu Zhao-qing du Xue-Min Liu Yi Lv Xu-Feng Zhang Department of Hepatobiliary Surgery and Institute of Advanced Surgical Technology and Engineering the First Affiliated Hospital of Xi'an Jiaotong University Xi'an 710061 Shaanxi Province China Shaanxi Provincial Regenerative Medicine and Surgical Engineering Research Center Xi'an 710061 Shaanxi Province China Department of Health Statistics the First Affiliated Hospital of Xi'an Jiaotong University Xi'an 710061 Shaanxi Province China

AIM: To analyze and compare postoperative morbidity between patients receiving total parenteral nutrition (TPN) and early enteral nutrition supplemented with parenteral nutrition (EEN + PN).METHODS: Three hundred and forty patients receiving pancreaticoduodenectomy (PD) from 2009 to 2013 at our center were enrolled retrospectively. Patients were divided into two groups depending on postoperative nutrition support scheme: an EEN + PN group (n = 87) and a TPN group (n = 253). Demographic characteristics, comorbidities, preoperative biochemical parameters, pathological diagnosis, intraoperative information, and postoperative complications of the two groups were ***: The two groups did not differ in demographic characteristics, preoperative comorbidities, preoperative biochemical parameters or pathological findings (P > 0.05 for all). However, patients with EEN + PN following PD had a higher incidence of delayed gastric emptying (16.1% vs 6.7%, P = 0.016), pulmonary infection (10.3% vs 3.6%, P = 0.024), and probably intraperitoneal infection (18.4% vs 10.3%, P = 0.059), which might account for their longer nasogastric tube retention time (9 d vs 5 d, P = 0.006), postoperative hospital stay (25 d vs 20 d, P = 0.055) and higher hospitalization expenses (USD10397 vs USD8663.9, P = 0.008), compared to those with ***: Our study suggests that TPN might be safe and sufficient for patient recovery after PD. Postoperative EEN should only be performed scrupulously and selectively.

关键词： Pancreaticoduodenectomy Postoperative complications Enteral nutrition Parenteral nutrition Delayed gastric emptying

Marketing　of　Libraries　and　Information　Centers　in　China:A　Case　Study

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情报理论与实践 1997年第2期20卷 35-41页

作者：Ｄｕ　Ｙｕａｎ　ｑｉｎｇＩｎｓｔｉｔｕｔｅ　ｆｏｒ　Ａｓｔｒｏｎａｕｔｉｃｓ　Ｉｎｆｏｒｍａｔｉｏｎ

ＭａｒｋｅｔｉｎｇｏｆＬｉｂｒａｒｉｅｓａｎｄＩｎｆｏｒｍａｔｉｏｎＣｅｎ┐ｔｅｒｓｉｎＣｈｉｎａ：ＡＣａｓｅＳｔｕｄｙ●ＤｕＹｕａｎｑｉｎｇ（ＩｎｓｔｉｔｕｔｅｆｏｒＡｓｔｒｏｎａｕｔｉｃｓＩｎｆｏｒｍａｔｉｏｎＢ... 详细信息

ＭａｒｋｅｔｉｎｇｏｆＬｉｂｒａｒｉｅｓａｎｄＩｎｆｏｒｍａｔｉｏｎＣｅｎ┐ｔｅｒｓｉｎＣｈｉｎａ：ＡＣａｓｅＳｔｕｄｙ●ＤｕＹｕａｎｑｉｎｇ（ＩｎｓｔｉｔｕｔｅｆｏｒＡｓｔｒｏｎａｕｔｉｃｓＩｎｆｏｒｍａｔｉｏｎＢｅｉｊｉｎｇ１０００１３）Ａｂｓｔ...

关键词： library Information center Marketing Information service China

Preparation of FeCoNi medium entropy alloy from Fe^(3+)-Co^(2+)-Ni^(2+)solution system

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 92-101页

作者： Zongyou Cheng qing Zhao Mengjie Tao Jijun du Xingxi Huang Chengjun Liu Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) Northeastern UniversityShenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China Engineering Research Center of Frontier Technologies for Low-carbon Steelmaking(Ministry of Education) Shenyang 110819China

In recent years,medium entropy alloys have become a research hotspot due to their excellent physical and chemical *** controlling reasonable elemental composition and processing parameters,the medium entropy alloys can exhibit similar properties to high entropy alloys and have lower *** this paper,a FeCoNi medium entropy alloy precursor was prepared via sol-gel and coprecipitation methods,respectively,and FeCoNi medium entropy alloys were prepared by carbothermal and hydrogen *** phases and magnetic properties of FeCoNi medium entropy alloy were *** showed that FeCoNi medium entropy alloy was produced by carbothermal and hydrogen reduction at 1500℃.Some carbon was detected in the FeCoNi medium entropy alloy prepared by carbothermal *** alloy prepared by hydrogen reduction was uniform and showed a relatively high ***,the hydrogen reduction product exhibited better saturation magnetization and lower coercivity.

关键词： medium entropy alloy sol-gel co-precipitation carbothermal hydrogen reduction

Linear porokeratosis of the foot with dermoscopic manifestations: A case report

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World Journal of Clinical Cases 2022年第31期10卷 11585-11589页

作者： Jing Yang Yi-qing du Xiao-Ya Fang Bo Li Zhi-Qin Xi Wen-Li Feng Department of Dermatology The Second Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Dermatology Gaoping City People’s HospitalGaoping 048400Shanxi ProvinceChina

BACKGROUND Porokeratosis(PK)is a common autosomal dominant chronic progressive dyskeratosis with various clinical *** on clinical manifestations,porokeratosis can be classified as porokeratosis of mibelli,disseminated superficial porokeratosis,disseminated superficial actinic porokeratosis,linear porokeratosis(LP),porokeratosis palmaris et plantaris disseminata,porokeratosis punctata,popular PK,hyperkeratosis PK,inflammatory PK,verrucous PK,and mixed *** report a case of LP in a child and describe its dermoscopic *** SUMMARY Linear porokeratosis is a rare *** patient presented with unilateral keratinizing maculopapular rash of the foot in *** patient underwent skin pathology and dermoscopy,and was treated with liquid nitrogen freezing and topical *** From this case we take-away that LP is a rare disease,by the dermoscopic we can identify it.

关键词： Porokeratosis Dermoscope Linear porokeratosis Genetic disease Chromosome Case report

Binding of PLCδ1PH-GFP to Ptdlns(4,5)P2 prevents inhibition of phospholipase C-mediated hydrolysis of Ptdlns(4,5)P2 by neomycin

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Acta Pharmacologica Sinica 2005年第12期26卷 1485-1491页

作者： Chuan WANG Xiao-na du qing-zhong JIA Hai-lin ZHANG~2 Department of Pharmacology Hebei Medical University,Shijiazhuang 050017,China Department of Pharmacology Hebei Medical University Shijiazhuang China

Aim:To investigate the effects of the pleckstrin homology(PH)domain of phos-pholipase Cδ1(PLCδ1PH)on inhibition of phospholipase C(PLC)-mediated hy-drolysis of phosphatidylinositol 4,5-bisphosphate[PtdIns(4,5)P2]by ***:A fusion construct of green fluorescent protein(GFP)and PLCδ1PH(PLCδ1PH-GFP),which is known to bind PtdIns(4,5)P2specifically,together withlaser-scanning confocal microscopy,was used to trace PtdIns(4,5)***:Stimulation of the type 1 muscarinic receptor and the bradykinin 2 recep-tor induced a reversible PLCδ1PH-GFP translocation from the membrane to thecytosol in COS-7 *** inhibitor U73122 blocked the ***,a known PtdIns kinase inhibitor,did not affect the translocationinduced by ACh,but blocked recovery after translocation,indicating thatPtdIns(4,5)P2hydrolysis occurs through receptor-mediated PLC ***,a commonly used phospholipase C blocker,failed to block the recep-tor-induced PLCδ1PH-GFP translocation,indicating that neomycin is unable toblock PLC-mediated Ptdlns(4,5)Pe ***,in the absence of PLCδ1PH-GFP expression,neomycin abolished the receptor-induced hydrolysis ofPtdIns(4,5)P2 by ***:Although PLCδ1PH and neomycin bind toPtdIns(4,5)P2 in a similar way,they have distinct effects on receptor-mediatedactivation of PLC and PtdIns(4,5)P2 hydrolysis.

关键词： phosphatidylinositol 4,5-bisphosphate neomycin phospholipase C pleckstrin homology domains competitive binding acetylcholine green fluorescent proteins

Optimized nitrogen application methods to improve nitrogen use efficiency and nodule nitrogen fixation in a maize-soybean relay intercropping system

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Journal of Integrative Agriculture 2018年第3期17卷 664-676页

作者： YONG Tai-wen CHEN Ping DONG Qian du qing YANG Feng WANG Xiao-chun LIU Wei-guo YANG Wen-yu College of Agronomy Sichuan Agricultural University/Key Laboratory of Crop Eco-physiology and Farming System in Southwest Ministry of Agriculture Chengdu 611130 P.R. China Shehong Farm Bureau Suining 629200 PR.China

In China, the abuse of chemical nitrogen （N） fertilizer results in decreasing N use efficiency （NUE）, wasting resources and causing serious environmental problems. Cereal-legume intercropping is widely used to enhance crop yield and improve resource use efficiency, especially in Southwest China. To optimize N utilization and increase grain yield, we conducted a two-year field experiment with single-factor randomized block designs of a maize-soybean intercropping system （IMS）. Three N rates, NN （no nitrogen application）, LN （lower N application： 270 kg N ha-1）, and CN （conventional N application： 330 kg N ha-1）, and three topdressing distances of LN （LND）, e.g., 15 cm （LND1）, 30 cm （LND2） and 45 cm （LND3） from maize rows were evaluated. At the beginning seed stage （R5）, the leghemoglobin content and nitrogenase activity of LND3 were 1.86 mg plant-1 and 0.14 mL h-1 plant-1, and those of LND1 and LND2 were increased by 31.4 and 24.5%, 6.4 and 32.9% compared with LND3, respectively. The ureide content and N accumulation of soybean organs in LND1 and LND2 were higher than those of LND3. The N uptake, NUE and N agronomy efficiency （NAE） of IMS under CN were 308.3 kg ha-1, 28.5%, and 5.7 kg grain kg-1 N, respectively; however, those of LN were significantly increased by 12.4, 72.5, and 51.6% compared with CN, respectively. The total yield in LND1 and LND2 was increased by 12.3 and 8.3% compared with CN, respectively. Those results suggested that LN with distances of 15-30 cm from the topdressing strip to the maize row was optimal in maize-soybean intercropping. Lower N input with an optimized fertilization location for IMS increased N fixation and N use efficiency without decreasing grain yield.

关键词： relay intercropping lower nitrogen nitrogen use efficiency nitrogen fixation nitrogen uptake

Characterization and Differentiation into Adipocytes and Myocytes of Porcine Bone Marrow Mesenchymal Stem Cells

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Journal of Integrative Agriculture 2014年第4期13卷 837-848页

作者： du Min-qing HUANG Yue-qin LU Nai-Sheng SHU Gang ZHU Xiao-tong WANG Li-na GAO Ping XI Qian-yun ZHANG Yong-liang WANG Song-bo JIANG qing-yan College of Animal Sciences South China Agricultural University

Bone marrow mesenchymal stem cells （BMSCs） could differentiate into various cell types including adipocytes and myocytes, which had important scientific significance not only in the field of tissue regeneration, but also in the field of agricultural science. In an attempt to exhibit the characterization and differentiation into adipocytes and myocytes of porcine BMSCs, we isolated and purified porcine BMSCs by red blood cell lysis method and percoll gradient centrifugation. The purified cells presented a stretched fibroblast-like phenotype when adhered to the culture plate. The results of flow cytometry analysis and immunofluorescence staining demonstrated that the isolated cells were positive for mesenchymal surface markers CD29, CD44 and negative for hematopoietic markers CD45 and the adhesion molecules CD31. Cells were induced to differentiate into adipocytes with adipogenic medium containing insulin, dexamethasone, oleate and octanoate. Oil Red O staining demonstrated that the porcine BMSCs successfully differentiated to adipocytes. Moreover, the findings of real-time PCR and Western blotting indicated that the induced cells expressed adipogenic marker genes （PPAR-y, C/EBP-c~, perilipin, aP2） mRNA or proteins （PPAR-3,, perilipin, aP2）. On the other hand, porcine BMSCs were induced into myoctyes with myogenic medium supplemented with 5-azacytidine, basic fibroblast growth factor, chick embryo extract and horse serum. Morphological observation by hochest 33342 staining showed that the induced cells presented as multi-nucleus muscular tube structure. And myogenic marker genes （Myf5, desmin） mRNA or proteins （MyfS, MyoD, myogenin, desmin） were found in the induced cells. In addition, the results of immunofluorescence staining revealed that myogenic marker （Myf5, MyoD, myogenin, desmin, S-MyHC） proteins was positive in the induced cells. Above all, these results suggested that the isolated porcine BMSCs were not only consistent with the characterization of mesenchyma

关键词： porcine bone marrow mesenchymal stem cell adipocyte myocyte