检索结果-南通市图书馆

Association of severity and sex with vasoactive substance and sexual hormone level in patients with vascular dementia in the type of kidney asthenia and blood stasis syndrome

引用

Neural Regeneration Research 2006年第9期1卷 813-816页

作者： jian du Jing cai Shuanghong Shen Geriatric Institute of Integrated Chinese and Western Medicine Fujian College of Traditional Chinese Medicine Fuzhou 350003 Fujian Province China Geriatric Institute of Integrated Chinese and Western MedicineFujian College of Traditional Chinese Medicine Fuzhou 350003 Fujian Province China Geriatric Institute of Integrated Chinese and Western MedicineFujian College of Traditional Chinese Medicine Fuzhou 350003 Fujian Province China

BACKGROUND: Kidney asthenia is the basic cause of the development of vascular dementia (VD). Kidney asthenia lasting for a long time will result in blood stasis. Also, the cause of VD may have relationships with endothelin (ET), nitric oxide (NO), homocysteine (HCY), estrogen (E2), and testosterone (T). OBJECTIVE: To observed clinical curative effect of the kidney tonic, pancreas tonic, and blood tonic with promoting blood circulation components in treating kidney asthenia with blood stasis syndrome of VD. DESIGN: Case controlled study. SETTING: Geriatric Institute of Integrated Medicine, Fujian College of Traditional Chinese Medicine. PARTICIPANTS: A total of 70 patients, including 39 males and 31 females aged 60-80 years, were selected from Department of Neurology, Pingshan Hospital from May 2000 to September 2002. Diagnostic criteria were used for probable VD of the American Psychiatric Association. Diagnostic and Statistical of Manual of Mental Disorder, 4th ed (DSM-Ⅳ), 1994 revised, mini-mental state examination (MMSE), and criteria of kidney asthenia with blood stasis with mixed weak and sthenia syndrome of Guidelines of Clinical Research of New Chinese Medicine in Treating Dementia. According to score of kidney asthenia with blood stasis syndrome, they were classified to three groups: mild (n =22), moderate (n =33) and severe (n =15). All of them with complete chest X-Ray, ECG, blood chemistry and other related examinations, exclusive of cardiovascular, liver, kidney diseases, homeopathy and psychiatry diseases. And hereby we also select 30 normal people as the comparing group, having no substantial diseases in heart, brain, kidney, liver, lung and other main organic systems after medical examination. Of this group, 11 were males and 19 were females, ranging from 62 years old to 78 years old. There were no obvious differences between the above two groups in sex, age, and education level after statistical analysis. All patients observed in Pingxi Hospital, Fuz

关键词： ET Association of severity and sex with vasoactive substance and sexual hormone level in patients with vascular dementia in the typ type

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Reference genes for quantitative real-time PCR analysis and quantitative expression of P5CS in Agropyron mongolicum under drought stress

引用

Journal of Integrative Agriculture 2016年第9期15卷 2097-2104页

作者： TIAN Qing-song WANG Shu-yan du jian-cai WU Zhi-juan LI Xiao-quan HAN Bing Institute of Grassland Research Chinese Academy of Agricultural Sciences Hohhot 010010 P.R. China gronomy College Inner Mongolia Agricultural University Hohhot 010010 P.R. China College of Life Science Inner Mongolia Agricultural University Hohhot 010010 P.R. China

Reference genes, stably expressing in different tissues and cells, are commonly used as the references in expression analysis. Selecting the optimum reference gene is crucial to the success of experiments. In this study, the expression stabilities of nine common reference genes, including ACT2, 18 S r RNA, APRT, EF-1α, RNA POL II, TUBα, TUBβ, GAPDH and TLF of Agropyron mongolicum, were studied under drought condition. Among them, 18 S r RNA was found to be the most optimum reference gene under drought stress by the analyzing of ge Norm and Norm Finder software. Quantitative expression levels of P5 CS using 18 S r RNA as the reference gene, and proline contents under drought stress in A. mongolicum were further operated, and we found the expression level of P5 CS gene and proline content had a significantly positive relationship（R^2=0.7763, P〈0.05）. This study established and validated 18 S r RNA as the reference genes in A. mongolicum under drought stress, providing a powerful tool for the quantitative expression analysis of drought genes in A. mongolicum.

关键词： reference genes quantitative real-time PCR drought stress proline pyrroline-5-carboxylic acid synthetase Agropyron mongolicum

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Anti-breast cancer effect of quercetin nanoparticles based on MOFs for chemo-phototherapy and heat shock proteins inhibition

引用

Nano Research 2025年第1期18卷 545-558页

作者： Rongyue Zhu Shilang Liao Mengru cai Dongge Yin Tingting Fu Jing Liu Yuji du Jiahui Kong Rongrong Chang jian Ni Xingbin Yin Beijing University of Chinese Medicine Fangshan DistrictBeijing 102488China

Phototherapy, including photodynamic therapy(PDT) and photothermal therapy (PTT), is a promisingmethod of tumor treatment, which has the advantages ofstrong specificity and small side effects. However, PDT willaggravate the hypoxic environment in tumor cells, and PTTwill lead to heat-resistant reaction, both of which will make theorganism quickly produce heat shock proteins (HSPs) toprotect itself, thus seriously hindering the therapeuticefficiency of phototherapy. As a natural HSPs inhibitor,quercetin (QR) provides a feasible way to solve this ***, a kind of metal organic framework (MOF), Fe-TCPP(FT), was used as a delivery material and photosensitizer tobuild a chemo-phototherapy platform, and QR was used as achemotherapy drug and HSPs inhibitor. On this basis, the nanoparticles (NPs) were modified with PEG-CPP30 (a cellpenetratingpeptide that specifically recognizes human breast cancer MCF-7 cells), which showed excellent targetingcapacity and biocompatibility. The combination of chemotherapy and phototherapy significantly improved the anti-cancereffect. At the same time, NPs also showed prominent anti-HSPs effect. The effective connection of the two played acomplementary role in the process of tumor treatment, which provided a new strategy for the accurate and efficienttreatment of tumors in the future.

关键词： quercetin Fe-metal organic frameworks(MOFs) phototherapy anti-cancer heat shock proteins inhibition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A novel method for simultaneous measurement of^(222)Rn and^(220)Rn progeny concentrations measured by an alpha spectrometer

引用

Nuclear Science and Techniques 2025年第1期36卷 127-139页

作者： Zhong-Kai Fan Jia-Le Sun Hao-Xuan Li Xiang-Ming cai Hui Yang Shou-Kang Qiu Yan-Liang Tan jian Shan School of Nuclear Science and Technology University of South ChinaHengyang 421001China College of Physics and Electronic Engineering Hengyang Normal UniversityHengyang 421008China

The accumulation of^(222)Rn and^(220)Rn progeny in poorly ventilated environments poses the risk of natural radiation exposure to the public.A previous study indicated that satisfactory results in determining the^(222)Rn and^(220)Rn progeny concentrations by measuring the total alpha counts at five time intervals within 560 min should be expected only in the case of high progeny concentrations in *** complete the measurement within a relatively short period and adapt it for simultaneous measurements at comparatively lower^(222)Rn and^(220)Rn progeny concentrations,a novel mathematical model was proposed based on the radioactive decay *** model employs a nonlinear fitting method to distinguish nuclides with overlapping spectra by utilizing the alpha particle counts of non-overlapping spectra within consecutive measurement cycles to obtain the concentrations of^(222)Rn and^(220)Rn progeny in *** verification experiments were conducted using an alpha *** experimental results demonstrate that the concentrations of^(222)Rn and^(220)Rn progeny calculated by the new method align more closely with the actual circumstances than those calculated by the total count method,and their relative uncertainties are all within±16%.Furthermore,the measurement time was reduced to 90 min,representing an acceleration of 84%.The improved capability of the new method in distinguishing alpha particles with similar energies emitted from ^(218)Po and^(212)Bi,both approximately 6 MeV,contributed to realizing more accurate *** proposed method has the potential advantage of measuring relatively low concentrations of^(222)Rn and^(220)Rn progeny in air more quickly via air filtration.

关键词： ^(222)Rn ^(220)Rn Progeny concentration Nonlinear fitting method Alpha spectrometer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

国家大剧院空调系统冷冻水变流量控制节能分析

引用

建筑热能通风空调 2017年第12期36卷 64-65,22页

作者：杜建财国家大剧院

本文主要是从国家大剧院中央空调水系统运行特点及运行使用费用上,分析了空调水系统的用电消耗与二次泵变流量系统节能运行之间的关系,并分别计算了冷冻水二次泵变流量系统不同运行频率下的总能耗及节能率。

关键词：变流量变频压差节能

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

宁夏猪暴露人群感染猪流感病毒现况调查

引用

现代预防医学 2015年第4期42卷 717-718+728页

作者：杜建财马江涛段军宁夏疾病预防控制中心中卫市疾病预防控制中心

目的通过调查宁夏猪暴露人群和猪群感染猪流感病毒的感染现况,为人感染猪流感病毒的防控提供科学依据。方法采用现况调查,利用多阶段抽样方法,收集屠宰场、规模养殖厂和散养户猪暴露人群的血清标本和猪鼻拭子标本;采用血凝抑制试验(HI)... 详细信息

目的通过调查宁夏猪暴露人群和猪群感染猪流感病毒的感染现况,为人感染猪流感病毒的防控提供科学依据。方法采用现况调查,利用多阶段抽样方法,收集屠宰场、规模养殖厂和散养户猪暴露人群的血清标本和猪鼻拭子标本;采用血凝抑制试验(HI),检测猪暴露人群感染猪流感病毒的抗体水平;利用real-time PCR的方法,对猪鼻拭子标本进行核酸检测。结果调查了猪暴露人群392名,血清标本未检出H1、H3亚型猪流感病毒抗体阳性标本;检测了408份猪鼻拭子标本,甲型通用猪流感核酸阳性感染率为15.69%(64/408),其中H1亚型阳性感染率为7.35%(30/408),H3、H4和H9亚型阳性检出率均为0。结论该区猪群中H1亚型猪流感病毒感染率相对较高,猪暴露人群中未发现人感染猪流感病毒的病例。

关键词：猪流感病毒猪暴露人群现况调查

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Carboniferous-Early Permian heterogeneous distribution of porous carbonate reservoirs in the Central Uplift of the South Yellow Sea Basin and its hydrocarbon potential analysis

引用

China Geology 2025年第1期8卷 58-76页

作者： Shu-yu Wu Jun Liu jian-wen Chen Qi-liang Sun Yin-guo Zhang Jie Liang Yong-cai Feng School of Engineering China University of GeoscienceWuhan 430074China Yantai Center of Coastal Zone Geological Survey China Geological SurveyMinistry of Natural ResourcesYantai 264001China Key Laboratory of Submarine Geosicences Ministry of Natural ResourcesHangzhou 310012China Chinese Academy of Geological Sciences China Geological SurveyMinistry of Natural ResourcesBeijing 100037China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266061China The Key Laboratory of Gas Hydrate Ministry of Natural ResourcesQingdao Institute of Marine GeologyChina Geological SurveyMinistry of Natural ResourcesQingdao 266071China College of Marine Science and Technology China University of GeoscienceWuhan 430074China

Mesozoic-Palaeozoic marine carbonate rocks are crucial hydrocarbon reservoirs in the Central Uplift area of the South Yellow Sea Basin(SYSB).due to the scarcity of boreholes and the significant heterogeneity of carbonate reservoirs,the distribution of porous carbonate reservoirs and their related key controlling factors remain *** this study,factors affecting the distribution of porous Carboniferous-Early Permian carbonate reservoirs in the SYSB were investigated through seismic inversion and isotope *** log-seismic characteristics of porous carbonate reservoirs,sensitive lithology parameters,and physical property parameters were extracted and *** pre-stack simultaneous inversion technique was applied to predict the lithology and physical properties of porous carbonate ***,the sedimentary of carbonate was analyzed using isotopes of carbon,oxygen,and *** results show that porous carbonate reservoirs are mainly developed in the open platform sediments with porosities of 3%-5%and are mainly distributed in the paleo-highland(Huanglong Formation and Chuanshan Formation)and the slope of paleo-highland(Hezhou Formation).The porous carbonate reservoirs of the Qixia Formation are only locally *** addition,the negativeδ13C excursions indicate a warm and humid tropical climate with three sea-level fluctuations in the study area from the Carboniferous to Early *** favorable conditions for developing porous carbonate rocks include the sedimentary environment and diagenetic *** primary pore tends to form in high-energy environments of the paleo-highland,and the secondary pore is increased by dissolution during the syngenetic or quasi-syngenetic *** to the hydrocarbon potential analysis,the Late Ordovician Wufeng Formation and Lower Silurian Gaojiabian Formation are the source rocks in the high-maturity-over-maturity stage,the Carboniferous-Lower Permian carbonate is the good reservoirs,and th

关键词： Sedimentary Heterogeneous porous carbonate reservoirs C-H-Sr isotope analysis Carboniferous-Early Permian Chuanshan Formation Huanglong Formation Pre-stack simultaneous inversion technique Oil-gas exploration engineering Hydrocarbon accumulation Hydrocarbon potential Central Uplift of the South Yellow Sea Basin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

隆德县7178例40~69岁人群上消化道癌筛查成本效果分析

引用

中华肿瘤防治杂志 2020年第23期27卷 1865-1869页

作者：杜建财杨艺刘红莉赵小丹宁夏回族自治区疾病预防控制中心慢病所宁夏银川750001 隆德县人民医院内镜室宁夏隆德756300 隆德县疾病预防控制中心慢病科宁夏隆德756300

目的分析2012-2018年隆德县上消化道癌筛查项目的成本效果,为制定上消化道癌防治策略提供参考。方法通过整群抽样,采用内镜下碘染(食管癌)和可疑病灶取活检的方式对隆德县40~69岁的居民进行筛查,收集筛查成本资料,计算发现阳性病例成本... 详细信息

目的分析2012-2018年隆德县上消化道癌筛查项目的成本效果,为制定上消化道癌防治策略提供参考。方法通过整群抽样,采用内镜下碘染(食管癌)和可疑病灶取活检的方式对隆德县40~69岁的居民进行筛查,收集筛查成本资料,计算发现阳性病例成本、发现早期病例成本以及发现早期病例成本系数。采用3%进行贴现率计算。结果2012-2018年共筛查目标人群7178例,检出阳性病例136例,早期病例101例。平均每检出1例阳性病例的成本21890元,每检出1例早期病例的成本29476元,早期发现成本系数1.73。结论在隆德县开展上消化道癌筛查具有较好的卫生经济学成本效果。

关键词：上消化道癌内镜筛查成本效果隆德县

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

银川市某体检人群脂肪肝与高尿酸血症、体重指数的相关性研究

引用

现代预防医学 2014年第24期41卷 4451-4453+4456页

作者：赵健郭忠琴陆波王云杜健财宁夏医科大学公共卫生学院流行病与卫生统计学系宁夏医科大学附属医学院

目的调查和评估脂肪肝在体检人群中的流行状况,探讨脂肪肝与高尿酸血症、体重指数之间的关系。方法收集6 984例体检人群相关资料,对1 752例健康体检B超检查确诊脂肪肝的受检者,根据高尿酸血症的诊断标准及体重指数的划分,对其进行相关... 详细信息

目的调查和评估脂肪肝在体检人群中的流行状况,探讨脂肪肝与高尿酸血症、体重指数之间的关系。方法收集6 984例体检人群相关资料,对1 752例健康体检B超检查确诊脂肪肝的受检者,根据高尿酸血症的诊断标准及体重指数的划分,对其进行相关性分析研究。结果本次体检者中脂肪肝的检出率为25.3%,脂肪肝患者中伴发有高尿酸血症的患病率为37.2%,脂肪肝与非脂肪肝患者中高尿酸血症的患病率差异有统计学意义(P<0.05),男性脂肪肝高尿酸血症检出率高于女性。脂肪肝与非脂肪肝患者中体重指数差异有统计学意义(P<0.05),随着体重指数增加,脂肪肝发病率增高。结论 (1)男性是脂肪肝的主要好发人群;(2)脂肪肝患者同时患有高尿酸血症的患病率明显高于非脂肪肝患者,脂肪肝与高尿酸血症有着一定的相关性;(3)体重指数与脂肪肝具有显著相关性。脂肪肝受多种因素影响,脂肪肝的防治不仅要注意肥胖的控制,还应注意高尿酸血症等相关疾病的治疗。

关键词：脂肪肝高尿酸血症体重指数相关性

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

干燥温度对禾本科牧草种子脱水速率和发芽率的影响

引用

中国草地学报 2016年第5期38卷 53-58页

作者：马金星屠德鹏寇建村冯葆昌杜建材全国畜牧总站农业部全国草业产品质量监督检验测试中心北京100125 北京林业大学林学院北京100083 西北农林科技大学动物科技学院陕西杨凌712100 中国农业科学院草原研究所内蒙古呼和浩特010010

为掌握入库前不同干燥温度对禾本科牧草种子的干燥效果,对14种禾本科牧草种子在湿度15±3%、温度分别为15±2℃和21±2℃条件下进行连续干燥,研究不同干燥温度下种子的脱水速率和发芽率。结果表明:(1)在温度15±2℃条件下干燥11d后,只... 详细信息

为掌握入库前不同干燥温度对禾本科牧草种子的干燥效果,对14种禾本科牧草种子在湿度15±3%、温度分别为15±2℃和21±2℃条件下进行连续干燥,研究不同干燥温度下种子的脱水速率和发芽率。结果表明:(1)在温度15±2℃条件下干燥11d后,只有巴哈雀稗种子含水量降至7%以下,达到入库标准;而在温度21±2℃条件下干燥,除匍匐翦股颖、披碱草和小黑麦外,其余11种牧草种子含水量均达到7%以下;(2)在两个温度下干燥后,草地早熟禾、多年生黑麦草、匍匐翦股颖发芽率显著降低(P<0.05),狗牙根、小黑麦、燕麦的发芽率变化不一,其余8种牧草种子发芽率干燥前后无显著变化。综合考虑,巴哈雀稗应在15±2℃干燥,冰草、多花黑麦草、高羊茅、紫羊茅、狗牙根、狼尾草、鸭茅应在21±2℃干燥,其余供试牧草的种子干燥方法还有待进一步研究。

关键词：禾本科种子干燥含水量发芽率

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：