检索结果-南通市图书馆

"反介入"战役及制胜要素——《反介入战争》第四章(三)

在线全文

学校读者我要写书评

暂无评论

兵器 2025年第1期 48-54页

作者： [美]萨姆·j.坦格里迪吴志丹(译) 不详

二战英国战役的胜利与纳粹失败的海狮行动被认为是二战转折点的英国战役,研究成果颇为丰硕。在纳粹对不列颠群岛发动空袭前,尽管德国海军在对英国海军和入侵挪威的战斗中不时会有损失,但德国陆军的“闪电战”从未失败过。

关键词：不列颠群岛英国海军研究成果纳粹转折点战役二战

Maximizing biomass utilization: An integrated strategy for coproducing multiple chemicals

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

j.urnal of Energy Chemistry 2025年第1期100卷 180-191页

作者： Byeongchan Ahn Sua j. j.nggeol Na j.j.y Liu Young-j. Kim Wangyun Won Department of Chemical and Biological Engineering Korea University Department of Chemical Engineering (Integrated process) Kyung Hee University Department of Chemical Engineering and Materials Science Ewha Womans University Department of Chemical Engineering Pukyong National University Resources Engineering Plant Research Department Korea Institute of Geoscience and Mineral Resources

Lignocellulosic biomass is one of the viable solutions to alleviate the global warming. However, the limited utilization of biomass maj.rly focused on cellulose and hemicellulose restricts the economic and environmental feasibilities. To cope with this issue, we proposed an integrated process of co-producing 1,6-hexanediol（1,6-HDO） with tetrahydrofuran and adipic acid from biomass, referred to as Strategy A. To compare the impacts of lignin upgrading and feedstock, Strategy B, which co-produces tetrahydrofuran alone, and Strategy C, which is the traditional route to produce 1,6-HDO from fossil fuels, were used. Heat networks are also designed to reduce operating costs and indirect carbon emissions due to energy consumption, saving 87% and 83% of the heat and cooling requirements, respectively, in Strategy A. The market competitiveness of Strategy A was evaluated by determining the minimum selling price through techno-economic analysis, and sustainability was thoroughly investigated by quantifying the environmental impacts through both midpoint and endpoint life-cycle assessments（LCAs）.Strategy A was found to be the most favorable both economically（USRDSCHARDOLLAR3,402/ton） and environmentally（-26.9 kg CO2eq.）. This indicates that lignin valorization is not only economically but also environmentally preferred. Finally, changes in economic and environmental feasibilities depending on economic, process, and environmental parameters were investigated using sensitivity and uncertainty analyses. The results of these analyses provide valuable insight into bio-based chemical production.

关键词： Carbon capture and utilization

j.ffery-Hamel flow of non-Newtonian fluid with nonlinear viscosity and wall friction

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2017年第6期38卷 815-830页

作者： j. NAGLER Department of Fluid Mechanics and Heat Transfer Faculty of Engineering Tel-Aviv University Ramat-Aviv 69978 Israel

A j.ffery-Hamel （j.H） flow model of the non-Newtonian fluid type inside a convergent wedge （inclined walls） with a wall friction is derived by a nonlinear ordinary differential equation with appropriate boundary conditions based on similarity relationships. Unlike the usual power law model, this paper develops nonlinear viscosity based only on a tangential coordinate function due to the radial geometry shape. Two kinds of solutions are developed, i.e., analytical and semi-analytical （numerical） solutions with suitable assumptions. As a result of the parametric examination, it has been found that the Newtonian normalized velocity gradually decreases with the tangential direction progress. Also, an increase in the friction coefficient leads to a decrease in the normalized Newtonian velocity profile values. However, an increase in the Reynolds number causes an increase in the normalized velocity function values. Additionally, for the small values of wedge semi-angle, the present solutions are in good agreement with the previous results in the literature.

关键词： j.ffery-Hamel (j.H) flow slip condition non-Newtonian fluid friction,nonlinear viscosity analytical solution numerical solution approximate solution

Combinatorial therapies for spinal cord inj.ry repair

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第5期20卷 1293-1308页

作者： Carla S.Sousa Andreia Monteiro António j.Salgado Nuno A.Silva Life and Health Sciences Research Institute(ICVS) School of MedicineUniversity of MinhoCampus de Gualtar-gualtarBragaPortugal ICVS/3B’s Associate Lab PT Government Associated LabCampus de Gualtar-gualtarBragaPortugal

Spinal cord inj.ries have profound detrimental effects on individuals, regardless of whether they are caused by trauma or non-traumatic events. The compromised regeneration of the spinal cord is primarily attributed to damaged neurons, inhibitory molecules, dysfunctional immune response, and glial scarring. Unfortunately, currently, there are no effective treatments available that can fully repair the spinal cord and improve functional outcomes. Nevertheless, numerous pre-clinical approaches have been studied for spinal cord inj.ry recovery, including using biomaterials, cells, drugs, or technological-based strategies. Combinatorial treatments, which target various aspects of spinal cord inj.ry pathophysiology, have been extensively tested in the last decade. These approaches aim to synergistically enhance repair processes by addressing various obstacles faced during spinal cord regeneration. Thus, this review intends to provide scientists and clinicians with an overview of pre-clinical combinatorial approaches that have been developed toward the solution of spinal cord regeneration as well as update the current knowledge about spinal cord inj.ry pathophysiology with an emphasis on the current clinical management.

关键词： electric stimulation neural tissue regeneration neuroprotection polytherapy spinal cord inj.ry

Segmentations of foreland belts and their tectonic mechanism in the Southwest Tarim Basin

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2005年第10期48卷 1585-1598页

作者： j. Canerot j. Deramond Lab. de Bassin Dynamique Sedimentaire Universite Paul Sabatier Toulouse III 39 Allee Jules-Guesde 31062 Toulouse FranceLab. de Bassin Dynamique Sedimentaire Universite Paul Sabatier Toulouse III 39 Allee Jules-Guesde 31062 Toulouse France

Based on lots of field investigations and comprehensive interpretations of seismic profiles with outcrop cross-sections, this paper shows that the foreland belts surrounding the Southwest Tarim Foreland Basin have the regularity of segmentation along the strike of foreland belts. There are many thin-skinned thrusting systems thrusting from mountains to the basin and the arcuate back-thrusting systems to the mountains distributed at intervals in the front of West Kunlun-Pamir and Southern Tianshan. Between thrusting and back-thrusting systems, the strike-slip faults developed. The northeast uplifts and depressions of Southwest Tarim Basin correspond with the segmentation of foreland basin. The thin-skinned thrusting system is formed in the case that the thickness of sedimentary covers is less than 10 km in depth where the basement is an uplift belt in general. The back-thrusting systems and triangle zones are formed in the case that the thickness of sedimentary covers is larger than 8 km in depth where the basement is a depression zone. The main mechanics of segmentation of foreland basin are the difference of mountain uplift and deformation rate along the longitude of the mountains, the huge sedimentary rocks in different depression centers, the uplift belts and depression zones in the basement rocks, and multi-displaced weak layers in the foreland basin. The segmentation of Southwest Tarim Foreland Basin is due to the intra-plate deformation of re-orogenies of West Kunlun-Pamir and Southwest Tianshan and the co-related deformation between mountains and basement of basin since Neocene.

关键词： Southwest Tarim Basin, foreland basin,West Kunlun-Pamir and Tianshan, tectonic segmentation,structure of basement.

Sleep as a window to understand and regulate Alzheimer's disease:emerging roles of thalamic reticular nucleus

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1711-1712页

作者： Haoqi Sun Shiqian Shen Robert j.Thomas M.Brandon Westover Can Zhang Department of Neurology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Center for Translational Pain Research Department of AnesthesiaCritical Care and Pain MedicineMassachusetis General HospitalHarvard Medical SchoolBostonMAUSA Division of Pulmonary Critical Care and Sleep MedicineDepartment of MedicineBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Genetics and Aging Research Unit McCance Center for Brain HealthMass General Institute for Neurodegenerative DiseaseDepartment of NeurologyMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA

Introduction:Alzheimer 's disease(AD) is a common neurodegenerative disorder and the primary cause of dementia. Considerable evidence supports the “amyloid hypothesis,” stating that the pathogenesis of AD is primarily caused by the deposition of amyloid-β(Aβ), which drives tau phosphorylation, neuroinflammation, and neurodegeneration in the brain. The amyloid hypothesis is strengthened by the significant and moderate benefit of lecanemab, a humanized antibody through an anti-amyloid mechanism,showing slowed clinical decline(van Dyck et al.,2023). The recent positive results of anti-amyloid trials have brought back focus on the amyloid hypothesis through biochemical, genetic, and pharmacological approaches(Zhang, 2023).

关键词： Alzheimer inflammation hypothesis

A structural topological optimization method for multi-displacement constraints and any initial topology configuration

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2010年第5期26卷 735-744页

作者： j. H. Rong j. H. Yi School of Automotive and Mechanical Engineering Changsha University of Science and TechnologyChangsha 410076 China

In density-based topological design, one expects that the final result consists of elements either black （solid material） or white （void）, without any grey areas. Moreover, one also expects that the optimal topology can be obtained by starting from any initial topology configuration. An improved structural topological optimization method for multidisplacement constraints is proposed in this paper. In the proposed method, the whole optimization process is divided into two optimization adj.stment phases and a phase transferring step. Firstly, an optimization model is built to deal with the varied displacement limits, design space adj.stments, and reasonable relations between the element stiffness matrix and mass and its element topology variable. Secondly, a procedure is proposed to solve the optimization problem formulated in the first optimization adj.stment phase, by starting with a small design space and advancing to a larger deign space. The design space adj.stments are automatic when the design domain needs expansions, in which the convergence of the proposed method will not be affected. The final topology obtained by the proposed procedure in the first optimization phase, can approach to the vicinity of the optimum topology. Then, a heuristic algorithm is given to improve the efficiency and make the designed structural topology black/white in both the phase transferring step and the second optimization adj.stment phase. And the optimum topology can finally be obtained by the second phase optimization adj.stments. Two examples are presented to show that the topologies obtained by the proposed method are of very good 0/1 design distribution property, and the computational efficiency is enhanced by reducing the element number of the design structural finite model during two optimization adj.stment phases. And the examples also show that this method is robust and practicable.

关键词： Topological optimization Displacement constraint Continuum structure Design space adj.stment Rational approximation material model

NECAB family of neuronal calcium-binding proteins in health and disease

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.E.Schafer Sudena Wang Michael j.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal EF-hand calcium-binding proteins 1–3(NECAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one EF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NECAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NECAB2 interacts with predominantly striatal G-protein-coupled receptors, while NECAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NECAB proteins exhibit distinct subcellular localizations: NECAB1 is found in the nucleus and cytosol, NECAB2 resides in endosomes and the plasma membrane, and NECAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NECAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NECAB proteins by controlling the availability of protein–protein interaction domains situated between the EF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium EF hand mitochondria nervous system signal transduction

Unimodal Sequences of Gorenstein Ideals of Codimension 4

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 1998年第4期14卷 563-568页

作者： Hyoung j. Ko Department of Mathematics. Yonsei University 134 Shinchon-dong Seodaemun-gu. Seoul Korea 120-749

We present Gorenstein ideals of condimension 4 which have unimodal Hilbert functions.

关键词： k-configuration Hilbert function Minimal free resolution Gorenstein ideal of codimension 4