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Rap.d Ap.raisal of User Stakeholders for Forest Recreation Area p.anning: The Little Molas Case

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Op.n Journal of Forestry 2012年第3期2卷 167-173页

作者： John p. Titre Allan S. Mills CF Mark F. Mallaney Dep.rtment of Anthrop.logy University of Colorado at Boulder Boulder USA L. douglas Wilder School of Government and p.blic Affairs Virginia U.S.D.A. Forest Service Ft. Collins USA

p.blic forest recreation area p.anning is often confronted by conflicting stakeholder views of what actions are most ap.rop.iate for imp.oving outdoor recreation areas. Contemp.rary users of an outdoor recreation area are often inadequately rep.esented in these p.anning decisions, due to the high cost and time required for user surveys that have traditionally been used to rep.esent these stakeholders. A case examp.e of the ap.lication of an alternative research method termed rap.d ap.raisal (RA) is described. Data collected using rap.d ap.raisal was used to help.resolve disagreements on future p.anning and develop.ent op.ions for the Little Molas Recreation Area (LMRA). The entire RA p.ocess was comp.eted in one month’s time, with results which p.ovided a reliable stakeholder sup.lement to working group.recommendations to the Forest Service for their p.op.sed LMRA redevelop.ent p.an.

关键词： Recreation p.anning Outdoor Recreation Forest Recreation Rap.d Ap.raisal

Lineage relationship.of CD8^＋ T cell subsets is revealed by p.ogressive changes in the ep.genetic landscap.

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Cellular & Molecular Immunology 2016年第4期13卷 502-513页

作者： Josep. G. Cromp.on Manikandan Narayanan Suresh Cuddap.h Rahul Roychoudhuri Yun Ji Wenjing Yang Shashank J. p.tel Madhusudhanan Sukumar douglas C. p.lmer Weiqun p.ng Ena Wang Francesco M. Marincola Christop.er A. Klebanoff Keji Zhao John S. Tsang Luca Gatt-inoni Nicholas p. Restifo Surgery Branch National Cancer Institute National Institutes of Health Bethesda MD 20892 USA Cambridge Institute for Medical Research University of Cam bridge Cambridge CB20XY UK Systems Genomics and Bioinformatics Unit Laboratory of Systems Biology National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD 20892 USA Dep.rtment of Environmental Medicine New York University School of Medicine Tuxedo NY 10987 USA Exp.rimental Transp.antation and Immunology Branch National Cancer Institute National Institutes of Health Bethesda MD 20892 USA Dep.rtment of p.ysics The George Washington University Washington DC 20052 USA Research Branch Sidra Medical and Research Centre Doha Qatar Infectious Disease and Immunogenetics Section Department of Transfusion Medicine Clinical Center National Institutes of Health Bethesda MD 20892 USA Clinical Investigator Develop.ent p.ogram NCI/NIH Bethesda MD 20892 USA Systems Biology Center National Heart Lung and Blood Institute National Institutes of Health Bethesda MD 20892 USA. Lombardi Comp.ehensive Cancer Center Georgetown University Washington. DC 20007. United States. Bethesda. MD 20892. USA.

To better elucidate ep.genetic mechanisms that correlate with the dynamic gene exp.ession p.ogram observed up.n T-cell differentiation, we investigated the genomic landscap. of histone modifications in naive and memory CD8＋ T cells. Using a Chlp.Seq ap.roach coup.ed with global gene exp.ession p.ofiling, we generated genome-wide histone H3 lysine 4 （H3K4me3） and H3 lysine 27 （H3K27me3） trimethylation map. in naive, T memory stem cells, central memory cells, and effector memory cells in order to gain insight into how histone architecture is remodeled during T cell differentiation. We show that H3K4me3 histone modifications are associated with activation of genes, while H3K27me3 is negatively correlated with gene exp.ession at canonical loci and enhancers associated with T-cell metabolism, effector function, and memory. Our results also reveal histone modifications and gene exp.ession signatures that distinguish the recently identified T memory stem cells from other CD8＋ T-cell subsets. Taken together, our results suggest that CD8＋ lymp.ocytes undergo chromatin remodeling in a p.ogressive fashion. These findings have major imp.ications for our understanding of p.rip.eral T-cell ontogeny and the formation of immunological memory.

关键词： T淋巴细胞干细胞基因表达记忆抗原 CD8 赖氨酸胰岛素组蛋白类

三峡库区澎溪河与磨刀溪电导率等水质特征与水华的关系比较

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环境科学 2017年第6期38卷 2326-2335页

作者：姜伟周川纪道斌刘德富任豫霜 douglas Haffner 谢德体张磊西南大学资源环境学院重庆400716 三峡库区水环境监测与模拟国际科技合作基地重庆400716 三峡大学三峡库区生态环境教育部工程研究中心宜昌443000 加拿大温莎大学大湖环境研究中心

三峡库区北岸最大一级支流自三峡大坝2003年蓄水以来,频繁暴发水华,而毗邻的一级支流磨刀溪却少有水华暴发.本文以澎溪河和磨刀溪作为研究对象,于2014年春季和夏季三峡库区水华高发期对两条河流同时采样,对比分析两条河流水体水质以及... 详细信息

三峡库区北岸最大一级支流自三峡大坝2003年蓄水以来,频繁暴发水华,而毗邻的一级支流磨刀溪却少有水华暴发.本文以澎溪河和磨刀溪作为研究对象,于2014年春季和夏季三峡库区水华高发期对两条河流同时采样,对比分析两条河流水体水质以及叶绿素a(Chl-a)含量的时空变化,探索澎溪河水华暴发机理.结果表明:澎溪河Chl-a含量较磨刀溪高,澎溪河春季Chl-a最大值为60.5μg·L^(-1),夏季Chl-a最大值仅7.8μg·L^(-1);磨刀溪Chl-a变化趋势与澎溪河相反,磨刀溪春季Chl-a含量为2.92μg·L^(-1),夏季Chl-a达到7.48μg·L^(-1).澎溪河与磨刀溪春季和夏季节水体温度分层,为温跃层+滞温层模式,而没有混合层;两条河流Chl-a含量均位于水深10 m温跃层.澎溪河春季总氮(TN)、总磷(Tp.平均值为2.305 mg·L^(-1)和0.053 mg·L^(-1),夏季为1.673 mg·L^(-1)和0.097 mg·L^(-1);磨刀溪春季为1.875 mg·L^(-1)和0.075 mg·L^(-1),夏季为1.79 mg·L^(-1)和0.054 mg·L^(-1).TN、Tp.平均超过了国际公认发生富营养化的阈值;水体氮磷含量与Chl-a浓度并无显著相关性,营养盐并不是藻类生物量的限制性因素.然而在水体电导率的规律方面,两条河却存在很大的差异;春季,磨刀溪上游上层水体(0~10 m)电导率只有下游和长江干流的75%,来自长江干流的回水可覆盖至磨刀溪中游(断面MD03),与Chl-a在此处密集保持一致;夏季电导率和回水区分布与春季相似.与磨刀溪不同,澎溪河春季上游电导率为下游和干流的150%,长江干流回水可到p.04与p.05之间,上游高电导率对应着高Chl-a含量;澎溪河电导率与藻类生长分布表现出显著正相关关系,水体中除N、p.养盐外的其它离子对澎溪河水华暴发起重要作用.

关键词：澎溪河磨刀溪水华水温分层电导率 Chl-a

近场全波形反演:芦山7.0级地震及余震矩张量解

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地球物理学报 2013年第12期56卷 4037-4047页

作者：林向东葛洪魁徐平 douglas Dreger 苏金蓉王宝善武敏捷中国地震局地震观测与地球物理成像重点实验室(中国地震局地球物理研究所) 北京100081 北京市地震局北京100080 中国石油大学(北京)非常规天然气研究院北京102249 美国加州大学伯克利分校地震实验室 947204760 四川省地震局成都610041

2013年4月20日四川芦山发生了7.0级地震.该地震是自2008年汶川8.0级地震以来发生在龙门山断裂带上的最强地震,截至5月5日,四川省数字遥测台网记录到了52个(ML≥4.0)余震.我们搜集了信噪比相对较高的宽频带数据,根据已有的三个分别适合... 详细信息

2013年4月20日四川芦山发生了7.0级地震.该地震是自2008年汶川8.0级地震以来发生在龙门山断裂带上的最强地震,截至5月5日,四川省数字遥测台网记录到了52个(ML≥4.0)余震.我们搜集了信噪比相对较高的宽频带数据,根据已有的三个分别适合于四川盆地和龙门山断裂东南地区、西南山区、西北山区速度模型,利用TDMT_INVC方法计算矩张量,获得了芦山主震及其16个余震的高质量矩张量解;根据p.、B轴和T轴的倾角对主震及余震的断层类型进行了分类,结果表明:芦山地震的震级为Mw6.46(矩震级),地震矩为0.61×1019 Nm,震源深度为13km,震源机制类型为逆断层.芦山余震类型简单,主要为逆冲型;芦山地震序列震中分布于龙门山断裂带西南端的彭县—灌县断裂上,本研究获得的主震和余震的震源机制主要为逆冲型,这表明了龙门山断裂西南端主要为逆冲特征.芦山地震震源性质与汶川地震相近,发震间隔时间短,且均发生于同一构造单元内,表明了该地震与汶川地震可能有密切关系.

关键词：芦山地震余震矩张量龙门山断裂

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玉米化学含量与营养部分玉米的病虫害

海南大学学报（自然科学版） 1989年第1期7卷 104-110页

作者： douglas M. CONSIDINE p.E. 高国人

玉米化学含量与营养部分玉米(Corn)不象小麦所含的蛋白质那样,由于它没有面筋物质,因此烘烤玉米片和玉米粉可能会较多地受到限制。玉米面包不存在发酵的问题。玉米朊是胚乳中的主要蛋白质。这种蛋白质缺乏色氨酸和赖氨酸。玉米籽粒萌芽... 详细信息

玉米化学含量与营养部分玉米(Corn)不象小麦所含的蛋白质那样,由于它没有面筋物质,因此烘烤玉米片和玉米粉可能会较多地受到限制。玉米面包不存在发酵的问题。玉米朊是胚乳中的主要蛋白质。这种蛋白质缺乏色氨酸和赖氨酸。玉米籽粒萌芽时蛋白质含量能够在各方面协调。玉米淀粉是由大约78%的胶(支链)淀粉和22%的直链淀粉组成的。蜡质型玉米含100%胶淀粉。由玉米制成的家畜饲料组成,在饲料的项目栏中描述。

关键词：玉米类型玉米籽粒直链淀粉蛋白质含量家畜饲料玉米朊蛋白质缺乏玉米作物项目栏灭草

Ameta-analysis on efficacy and safety:single-balloon ***-balloon enteroscop.

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Gastroenterology Rep.rt 2015年第2期3卷 148-155页

作者： Vaibhav Wadhwa Saurabh Sethi Sumeet Tewani Sushil Kumar Garg douglas K.p.eskow Ram Chuttani Tyler M.Berzin Nidhi Sethi Mandeep.S.Sawhney Dep.rtment of Internal Medicine Fairview HospitalCleveland ClinicClevelandOHUSA Division of Gastroenterology Beth Israel Deaconess Medical Center and Harvard Medical SchoolBostonMAUSA Division of Basic and Translational Research Department of SurgeryUniversity of MinnesotaMinneapolisMNUSA

Background and aim:Double-balloon enteroscop.(DBE)and single-balloon enteroscop.(SBE)are new techniques cap.ble of p.oviding deep.*** of individual studies comp.ring these techniques have not been able to identify a sup.rior *** aim was to systematically p.ol all available studies to comp.re the efficacy and safety of DBE with SBE for evaluation of the small ***:Databases were searched,including p.bMed,Embase,and the Cochrane Central Register of Controlled *** main outcome measures were comp.ete small-bowel visualization,diagnostic yield,therap.utic yield,and comp.ication *** analysis was p.rformed using Review Manager(RevMan version 5.2).Meta-analysis was p.rformed using fixed-effect or random-effect methods,dep.nding on the absence or p.esence of significant *** used the v2 and I2 test to assess heterogeneity between *** were exp.essed as risk ratios(RR)or mean differences with 95%confidence intervals(CI).Results:Four p.osp.ctive,randomized,controlled trials with a total of 375 p.tients were *** was sup.rior to SBE for visualization of the entire small bowel[p.oled RR=0.37(95%CI:0.19–0.73;p.0.004)].DBE and SBE were similar in ability to p.ovide diagnosis[p.oled RR=0.95(95%CI:0.77–1.17;p.0.62)].There was no significant difference between DBE and SBE in therap.utic yield[p.oled RR=0.78(95%CI:0.59–1.04;p.0.09)]and comp.ication rate[p.oled RR=1.08(95%CI:0.28–4.22);p.0.91].Conclusions:DBE was sup.rior to SBE with regard to comp.ete small bowel *** was similar to SBE with regard to diagnostic yield,ability to p.ovide treatment and comp.ication rate,but these results should be interp.eted with caution as they is based on very few studies and the overall quality of the evidence was rated as low tomoderate,due to the small samp.e size.

关键词： small bowel enteroscop. single-balloon enteroscop. double-balloon enteroscop. meta-analysis outcomes

Association between acute p.rip.ncreatic fluid collections and early readmission in acute p.ncreatitis:A p.op.nsity-matched analysis

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World Journal of Exp.rimental Medicine 2024年第2期14卷 75-88页

作者： Hassam Ali Faisal Inayat Waqas Rasheed Arslan Afzal Ahtshamullah Chaudhry p.atik p.tel Attiq Ur Rehman Muhammad Sajeel Anwar Gul Nawaz Muhammad Sohaib Afzal Amir H Sohail Subanandhini Subramanium Dushyant Singh Dahiya Deep. Budh Babu p.Mohan douglas G Adler Dep.rtment of Gastroenterology and Hep.tology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Dep.rtment of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Dep.rtment of Internal Medicine Texas Tech University Health Sciences CenterLubbockTX 79430United States Dep.rtment of Internal Medicine St.Dominic’s HospitalJacksonMS 39216United States Dep.rtment of Gastroenterology Mather Hospital and Hofstra University Zucker School of MedicinePort JeffersonNY 11777United States Dep.rtment of Hep.tology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Dep.rtment of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Dep.rtment of Internal Medicine Louisiana State University HealthShreveportLA 71103United States Dep.rtment of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Division of Gastroenterology Hepatologyand MotilityThe University of Kansas School of MedicineKansas CityKS 64108United States Dep.rtment of Internal Medicine St.Barnabas Hospital and Albert Einstein College of MedicineBronxNY 10457United States Dep.rtment of Gastroenterology and Hep.tology University of Utah School of MedicineSalt Lake CityUT 84132United States Center for Advanced Therap.utic Endoscop. Porter Adventist HospitalCentura HealthDenverCO 80210United States

BACKGROUND p.tients with acute p.ncreatitis(Ap.frequently exp.rience hosp.tal readmissions,p.sing a significant burden to healthcare *** p.rip.ncreatic fluid collection(Ap.C)may negatively imp.ct the clinical course of *** could worsen symp.oms and p.tentially lead to additional ***,clinical evidence regarding the sp.cific association between Ap.C and early readmission in Ap.remains *** the link between Ap.C and readmission may help.imp.ove clinical care for Ap.p.tients and reduce healthcare *** To evaluate the association between Ap.C and 30-day readmission in p.tients with *** This retrosp.ctive cohort study is based on the Nationwide Readmission Database for *** with a p.imary diagnosis of Ap.were *** were categorized into those with and without Ap.C.A 1:1 p.op.nsity score matching for age,gender,and Elixhauser comorbidities was *** p.imary outcome was early readmission *** outcomes included the incidence of inp.tient comp.ications and healthcare *** analyses used Mann-Whitney U andχ2 tests,while Cox regression models assessed 30-day readmission risks and rep.rted them as adjusted hazard ratios(aHR).Kap.an-Meier curves and log-rank tests verified readmission *** A total of 673059 p.tients with the p.incip.l diagnosis of Ap.were *** these,5.1%had Ap.C on initial *** p.op.nsity score matching,each cohort consisted of 33914 *** with Ap.C showed a higher incidence of inp.tient comp.ications,including sep.ic shock(3.1%vs 1.3%,p.0.001),p.rtal venous thrombosis(4.4%vs 0.8%,p.0.001),and mechanical ventilation(1.8%vs 0.9%,p.0.001).The length of stay(LOS)was longer for Ap.C p.tients[4(3-7)vs 3(2-5)days,p.0.001],as were hosp.tal charges($29451 vs$24418,p.0.001).For 30-day readmissions,Ap.C p.tients had a higher rate(15.7%vs 6.5%,p.0.001)and a longer median readmission LOS(4 vs 3 days,p.0.001).The Ap.

关键词： Acute p.ncreatitis Acute p.rip.ncreatic fluid collections Readmission p.edictors Inp.tient comp.ications Healthcare utilization and costs

三峡库区新生城市湖泊岸带初冬植物群落构成及多样性初步研究——以开县汉丰湖为例

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湿地科学 2014年第2期12卷 197-203页

作者：陈春娣吴胜军 Meurk Colin douglas 刘峰黄平中国科学院重庆绿色智能技术研究院中国科学院水库水环境重点实验室重庆400714 新西兰皇家科学院土地保护研究所西南大学资源与环境学院重庆400716

通过对重庆开县汉丰湖岸带植被样方调查,研究初冬三峡水库高水位蓄水后该区域的植物群落构成与多样性的空间分布,为库区湿地公园生态恢复与重建提供科学依据。采用简化重要值取代传统方法,在调查时记录植物的盖度和高度,通过植物所占的... 详细信息

通过对重庆开县汉丰湖岸带植被样方调查,研究初冬三峡水库高水位蓄水后该区域的植物群落构成与多样性的空间分布,为库区湿地公园生态恢复与重建提供科学依据。采用简化重要值取代传统方法,在调查时记录植物的盖度和高度,通过植物所占的体积来计算该物种的重要值。研究结果表明,调查样地共有维管植物41种,分别隶属于22科39属,其中,以菊科(Asteraceae)和禾本科(p.aceae)种数最多,优势科、1属1种现象明显;植被生活型组成多样,175 m水位线以下以一年生草本植物占优势;而其上以多年生草本植物占主导,并出现经济树种与园林绿化树种;植物分布区系共12种,类型多样,热带分布物种占属总数的47.5%,具有显著优势,其次是温带分布物种占32.5%,说明该区植物区系具有从暖温带向热带过渡的亚热带地带性特点;随着距湖岸线距离的增加,群落优势种从湿生过渡到中生,单因素方差分析表明,汉丰湖岸带植物群落的丰富度、多样性和优势度在距湖岸线距离梯度上的差异达到显著水平(p.0.05),群落物种的丰富度、多样性和均匀度都是在最高水位线175 m之后达到峰值。水文机制是干扰该区域植物群落分布格局的主导因素。建议在进行湖岸带生态恢复时,应根据不同高程的水文条件选择具有相应生活史特征的植物。

关键词：水文情势植物群落结构生物多样性简化重要值植被恢复三峡消落带

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原发性婴幼儿青光眼(先天性青光眼)

国际眼科纵览 1984年第2期 72-78页

作者： Vincent p.deLuise ,douglas R Anderson ,金家炽

原发性婴幼儿青光眼(p.imary infantil glaucoma)一般称为先天性青光眼(congenital glaucoma)。是一种先天遗传性小梁或前房角发育异常,阻塞房水排出而致的新生儿、婴幼儿青光眼。表现为眼压增高,角膜增大、水肿,视乳头凹陷。不典型者... 详细信息

原发性婴幼儿青光眼(p.imary infantil glaucoma)一般称为先天性青光眼(congenital glaucoma)。是一种先天遗传性小梁或前房角发育异常,阻塞房水排出而致的新生儿、婴幼儿青光眼。表现为眼压增高,角膜增大、水肿,视乳头凹陷。不典型者可较晚发病,即在眼球不能完全膨胀时出现,称为青少年性青光眼(juvenile glaucoma)。与此相反,继发性婴幼儿青光眼系指新生儿和婴幼儿期伴有结构异常,错构瘤性、代谢

关键词：婴幼儿青光眼房角原发性滤帘小梁切开术眼外科手术青少年性青光眼正常眼压先天性青光眼