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Free perforation of the small intestine in collagenous sprue

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World Journal of Gastroenterology 2009年第35期15卷 4446-4448页

作者： Hugh J Freeman douglas L Webber Departments of Medicine(Gastroenterology) University of British ColumbiaVancouverBC V6T 1W5Canada Departments of Pathology University of British ColumbiaVancouverBC V6T 1W5Canada

A 67-year-old man with celiac disease developed recurrent diarrhea,profound weakness and weight loss, with evidence of marked protein *** clinical course was refractory to a strict gluten-free diet and steroid *** studies led to definition of unrecognized collagenous sprue that caused ulceration and small intestinal *** PCR showed identical monoclonal T-cell populations in antemortem duodenal biopsies and postmortem jejunum,careful pathological evaluation demonstrated no frank ***,overt or even cryptic T-cell lymphoma may complicate collagenous sprue,however, small intestinal ulcers and perforation may also develop *** dramatic findings here may reflect an underlying or early molecular event in the eventual clinical appearance of overt T-cell lymphoma.

关键词： Collagenous sprue Intestinal perforation Celiac disease Refractory sprue Intestinal neoplasms Lymphoma

Honour and Kingship in Herodotus: Status, Role, and the Limits of Self-Assertion

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Frontiers of Philosophy in China 2019年第1期14卷 75-93页

作者： douglas Cairns Department of Classics University of Edinburgh EH8 9AG Scotland UK

The notion of time(Tiμη, normally translated "honour") is a key concept when it comes to thinking about virtues, roles, and duties in ancient Greek ethics and society, both in popular and in philosophical terms. This discussion concentrates on the work of the fifth-century historian, Herodotus, where the idea of time as the fulfilment of a specific role in society takes on particular and interesting inflections. In Herodotus, as in Greek generally, time covers both the esteem that one receives from others and the claim to esteem that the individual him- or herself brings to bear in social interaction. Thus time is both "deference" and "demeanour"(to use Goflman's terminology). As a quality of an individual that commands others' respect, time also encompasses the roles that are bound up with one's status. Roles and offices express, attract, and demand time, but such demands are normally constrained by reciprocal respect for the time of others. The office of the Persian king, however, appears at first sight to involve unconditional claims to recognition respect, powerful drives towards appraisal respect (in DarwalPs terminology), and only limited acknowledgement of either ethical norms or others claims as potential limitations to regal self-assertion. Closer inspection, however, reveals that the values of mutual respect that underpin the freedom enjoyed by citizens of Greek poleis are also felt by Herodotus to ground claims to freedom and in dependence on the part of those poleis themselves, claims that the historian9s narrative suggests are ultimately upheld by the gods and embedded in the structure of the cosmos itself.

关键词： Herodotus honour time Persian wars Xerxes

Donald Trump, Globalization, and Modernity

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Fudan Journal of the Humanities and Social Sciences 2018年第3期11卷 265-284页

作者： douglas Kellner UCLA Los Angeles CA USA

The election of Donald Trump can be partially understood in the context of the rise of authoritarian populist, nationalist, and anti-globalist movements throughout the world. Unlike previous American presidents in the modern era, however, Donald Trump had no previous political experience and emerged from media culture and the business world, rather than the world of party politics. In this paper, I will focus on the assault on globalization in the Trump campaign, look at his administration and actions as president, and raise questions concerning whether or not he has betrayed his anti-globalist followers and is pursing business-as-usual for global, corporate capitalism---or something else. This investigation also leads us into engaging the Trump campaign/administration connections with Russia and the role of Russia and global computer networks in Election 2016, making Election 2016 the first US election deeply shaped by global political forces and the Interuet, new media, and social networking.

关键词： Donald Trump Authoritarian populism US presidentialelection Globalization Modernity

Donald *** memoir—exceptional seismologist,teacher,mentor,friend

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Earthquake Science 2022年第1期35卷 26-28页

作者： douglas Dreger University of California BerkeleyCA 94720USA

Donald *** was an unparalleled observational seismologist,and *** pioneering work in seismic waveform modeling,and the numerical methods he developed to simulate seismograms to study the structure of the Earth and the... 详细信息

关键词： seism earthquake Earth

Arthropods and biofuel production systems in North America

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Insect Science 2010年第3期17卷 220-236页

作者： douglas A. Landis Benjamin P. Werling Department of Entomology and Great Lakes Bioenergy Research Center 204 Center for Integrated Plant Systems Michigan State University East Lansing Michigan USA

Biomass harvest may eventually be conducted on over 100 000 000 ha of US crop and forest lands to meet federally-mandated targets for renewable biofuels. Such largescale land use changes could profoundly impact working landscapes and the arthropod communities that inhabit them. We review the literature on dedicated biofuel crops and biomass harvest from forests to look for commonalities in arthropod community responses. With expanded biofuel production, existing arthropod pests of biofuel crops will likely become more important and new pests will emerge. Beneficial arthropods will also be influenced by biofuel crop habitats, potentially altering the distribution of pollination and pest control services to the surrounding landscape. Production of biofuel crops including initial crop selection, genetic improvement, agronomic practices, and harvest regimes will also influence arthropod communities. In turn, arthropods will impact the productivity and species composition of biomass production systems. Some of these processes have the potential to cause landscape-level changes in arthropod community dynamics and insect- vectored plant diseases. Finally, changes in arthropod populations and their spatiotemporal distribution in the landscape will have impacts on consumers of insects at higher trophic levels, potentially influencing their population and community dynamics and producing feedbacks to arthropod communities. Given that dedicated biofuel crops and intensified biomass harvest from forests are still relatively uncommon in North America, as they increase, we anticipate ＇predictably unpredictable＇ shifts in arthropod communities and the ecosystem services and functions they support. We suggest that research on arthropod dynamics within biofuel crops, their spillover into adjacent habitats, and implications for the sustainability of working landscapes are critical topics for both basic and applied investigations.

关键词： biodiversity land use change pest management

The paternal epigenome and embryogenesis： poising mechanisms for development

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Asian Journal of Andrology 2011年第1期13卷 76-80页

作者： Timothy G Jenkins douglas T Carrell Andrology and IVF Laboratories Department of Surgery University of Utah Salt Lake City UT 84108 USA Department of Obstetrics and Gynecology University of Utah School of Medicine Salt Lake City UT 84108 USA Department of Physiology University of Utah School of Medicine Salt Lake City UT 84108 USA

The scope of paternal contributions during early embryonic development has long been considered limited. Dramatic changes in chromatin structure throughout spermatogenesis have been thought to leave the sperm void of complex layers of epigenetic regulation over the DNA blueprint, thus leaving the balance of that regulation to the oocyte. However, recent work in the fields of epigenetics and male factor infertility has placed this long-held, and now controversial dogma, in a new light. Elegant studies investigating chromatin and epigenetic modifications in the developing sperm cell have provided new insights that may establish a more critical role for the paternal epigenome in the developing embryo. DNA methylation, histone tail modifications, targeted histone retention and protamine incorporation into the chromatin have great influence in the developing sperm cell. Perturbations in the establishment and/or maintenance of any of these epigenetic marks have been demonstrated to affect fertility status, ranging in severity from mild to catastrophic. Sperm require this myriad of chromatin structural changes not only to serve a protective role to DNA throughout spermatogenesis and future delivery to the egg, but also, it appears, to contribute to the developmental program of the future embryo. This review will focus on our current understanding of the epigenetics of sperm. We will discuss sperm-specific chromatin modifications that result in genes essential to development being poised for activation early in embryonic development, the disruption of which may result in reduced fecundity.

关键词： chromatin DNA methylation embryogenesis epigenetics histone modification male infertility

Assessing Potential Earthquake Loss in Me′rida State, Venezuela Using Hazus

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International Journal of Disaster Risk Science 2014年第3期5卷 176-191页

作者： América Bendito Jesse Rozelle douglas Bausch Civil Engineering Department Universidad de Los AndesMe´rida 5101Venezuela Mitigation Division Federal Emergency Management Agency(FEMA)Region VIIIDenverCO 80225USA

The focus of the Hazus earthquake model has been largely U.S. centric due to a lack of standardized building-infrastructure data formats applicable *** a combined effort between FEMA Region VIII and the Universidad de Los Andes, Venezuela, the present study uses the Hazus 2.1 software to simulate earthquake loss estimations for Venezuela. Population totals and demographic distributions were developed using Oak Ridge National Labs Landscan 2008 population data and the census 2011 for Venezuela. The accuracy of the model was further enhanced for Me′rida State, located in western Venezuela, by collecting, incorporating, and developing region and specific inventories including soil maps, liquefaction and landslide susceptibility studies, demographic data, and building inventory information. We used USGS Shake Maps scenarios for two potential earthquake events with peak ground accelerations proposed within Performance Based Seismic Engineering of Buildings, VISION 2000 recommendations. The region has not witnessed an earthquake with a magnitude greater than M 7 in the last120 years. Given the historical record of seismicity and the seismotectonics in the region, it becomes increasingly important to understand the potential implications from moderate to large earthquakes in Me′rida State, Venezuela.

关键词： Disaster loss estimation Earthquake damage Hazus Seismic risk Venezuela

HYERS-ULAM STABILITY OF SECOND-ORDER LINEAR DYNAMIC EQUATIONS ON TIME SCALES

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Acta Mathematica Scientia 2021年第5期41卷 1809-1826页

作者： douglas R.ANDERSON Masakazu ONITSUKA Department of Mathematics Concordia CollegeMoorheadMN 56562 USA Department of Applied Mathematics kayama University of ScienceOkayama700-0005Japan

We investigate the Hyers-Ulam stability(HUS)of certain second-order linear constant coefficient dynamic equations on time scales,building on recent results for first-order constant coefficient time-scale *** particular,for the case where the roots of the characteristic equation are non-zero real numbers that are positively regressive on the time scale,we establish that the best HUS constant in this case is the reciprocal of the absolute product of these two *** for instability are also given.

关键词： stability second order Hyers-Ulam time scales

Rib Osteosynthesis for Sub-Acute Management of a Flail Chest in a Tertiary Centre in a Low-Middle Income Country of Sub-Saharan Africa: Case Report at Douala Laquintinie Hospital

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Open Journal of Thoracic Surgery 2024年第1期14卷 1-16页

作者： Fabrice Stéphane Arroye Betou Nyankoue Mebouinz Ferdinand Guy Aristide Bang Kobe Folkabo Zephany Banga Nkomo douglas Moussa Seck Diop Abdoul Lahad Mbeng Marcella Derboise Christelle Biyouma Noel Essomba Souleyman Diatta Handy Eone Daniel Arthur Essomba Hassan Ndiaye Maurice Aurelien Sosso Department of Surgery and Specialties Faculty of Medicine and Biomedical Sciences (FMBS) University of Yaoundé (UYI) Yaoundé Cameroon Department of Surgery and Affiliated Disciplines Douala Laquintinie Hospital Douala Cameroon Department of Surgery and Specialties Yaoundé General Hospital Yaoundé Cameroon Department of Surgery and Specialties Faculty of Medicine and Pharmaceutical Sciences (FMPS) University of Dschang Dschang Cameroon Service de Chirurgie Thoracique et Cardiovasculaire Centre Hospitalier Universitaire de Fann Faculté de Médecine de Pharmacie et d’Odontologie Université de Cheikh Anta Diop Dakar Sénégal UFR des Sciences de la Santé Ziguinchor Sénégal

Background: Costal fracture surgical is still a debate, therefore we shall select between early and delay surgical management. Case Report: We are reporting two cases of post road traffic clash delay ribs fractures osteosynthesis involving a 63-year-old man with multistage fractures on the left and pulmonary pinning of one of the costal arches, complicated by a homolateral haemothorax and a 41-year-old man with a bilateral flail chest. Conclusion: The simple postoperative course and the immediate postoperative improvement in the patient’s clinical respiratory condition enabled us to discuss the time frame for management, in this case the indication for early or later surgery.

关键词： Flail Chest Fixation Plate Rib Fracture Osteosynthesis