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Clinical and genetic characteristics of a child with Sotos syndrome and attention-deficit/hyperactivity disorder:A case report

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World Journal of Clinical Cases 2024年第22期12卷 5131-5139页

作者： Ya-Jing Yang Bei-Yi Li Ke-Xin Gan Jing Liu Xiu-Qin Lv dong-mei zhang Hui-Juan Ma Department of Internal Medicine North China University of Science and TechnologyTangshan 063000Hebei ProvinceChina Department of Internal Medicine Hebei Medical UniversityShijiazhuang 050017Hebei ProvinceChina Department of Endocrinology Hebei General HospitalShijiazhuang 050000Hebei ProvinceChina Department of Endocrinology The First Hospital of Hebei Medical UniversityShijiazhuang 050023Hebei ProvinceChina

BACKGROUND Sotos syndrome is an autosomal dominant disorder,whereas attention-deficit/hyperactivity disorder(ADHD)is a neurodevelopmental *** report aimed to summarize the clinical and genetic features of a pediatric case of Soros syndrome and ADHD in a child exhibiting precocious *** SUMMARY The patient presented with accelerated growth and advanced skeletal maturation;however,she lacked any distinct facial characteristics related to specific genetic *** analyses revealed a paternally inherited heterozygous synonymous mutation[c.4605C>T(***1535Arg)].Functional analyses suggested that this mutation may disrupt splicing,and bioinformatics analyses predicted that this mutation was likely *** an initial diagnosis of Sotos syndrome,the patient was diagnosed with ADHD during the follow-up period at the age of 8 years and 7 *** The potential for comorbid ADHD in Sotos syndrome patients should be considered to avoid the risk of a missed diagnosis.

关键词： Sotos syndrome Attention-deficit/hyperactivity disorder Nuclear receptor binding SET domain protein 1 Case report Developmental disabilities Diagnosis Como rbidity Management

Distributed H_∞ PID Feedback for Improving Consensus Performance of Arbitrary-delayed Multi-agent System

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International Journal of Automation and computing 2014年第2期11卷 189-196页

作者： Lin-Lin Ou Jun-Jie Chen dong-mei zhang Lin-zhang Wei-dong zhang Department of Automation Zhejiang University of Technology Department of Automation Shanghai Jiaotong University

The H∞ proportional-integral-differential(PID) feedback for arbitrary-order delayed multi-agent system is investigated to improve the system performance. The closed-loop multi-input multi-output(MIMO) control framework with the distributed PID controller is firstly described for the multi-agent system in a unified way. Then, by using the matrix theory, the prescribed H∞performance criterion of the multi-agent system is shown to be equivalent to several independent H∞ performance constraints of the single-input single-output(SISO) subsystem with respect to the eigenvalues of the Laplacian matrix. Subsequently, for each subsystem,the set of the PID controllers satisfying the required H∞ performance constraint is analytically characterized based on the extended Hermite-Biehler theorem. Finally, the three-dimensional set of the decentralized H∞ PID control parameters is derived by finding the intersection of the H∞ PID regions for all the decomposed subsystems. The simulation results reveal the effectiveness of the proposed method.

关键词： Multi-agent system proportional-integral-differential(PID) controller H∞ performance index parametric space consensus.

A practical ANN model for predicting the excavation-induced tunnel horizontal displacement in soft soils

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Underground Space 2022年第2期7卷 278-293页

作者： Zhong-Kai Huang dong-mei zhang Xiao-Chuang Xie Key Laboratory of Geotechnical and Underground Engineering of Ministry of Education Department of Geotechnical EngineeringTongji UniversityShanghaiChina

The objective of this study is to propose an artificial neural network(ANN)model to predict the excavation-induced tunnel horizontal displacement in soft *** this purpose,a series of finite element data sets from rigorously verified numerical models were collected to be utilized for the development of the ANN *** excavation width,the excavation depth,the retaining wall thickness,the ratio of the average shear strength to the vertical effective stress,the ratio of the average unloading/reloading Young’s modulus to the vertical effective stress,the horizontal distance between the tunnel and retaining wall,and the ratio of the buried depth of the tunnel crown to the excavation depth were chosen as the input variables,while the excavation-induced tunnel horizontal displacement was considered as an output *** results demonstrated the feasibility of the developed ANN model to predict the excavation-induced tunnel horizontal *** proposed ANN model in this study can be applied to predict the excavation-induced tunnel horizontal displacement in soft soils for practical risk assessment and mitigation decision.

关键词： Artificial neural network Excavation Tunnel horizontal displacement Soft soils

Two New Coumarins from Fraxinus chinensis Rexb.

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Journal of Integrative Plant Biology 2007年第2期49卷 218-221页

作者： dong-mei zhang Li-Li Wang Jia Li Li-Hong Hu Shanghai Research Center for Modernization of Traditional Chinese Medicine Shanghai Institute of Materia Medica Shanghai Institute for Biological Sciences the Chinese Academy of Sciences Shanghai 201203 China National Center for Drug Screening Shanghai Institute of Materia Medica Shanghai Institutes for Biological Sciences the Chinese Academy of Sciences Shanghai 201203 China School of Pharmacy East China University of Science and Technology Shanghai 200237 China

The ethanol extract of the stem bark of Fraxinus chinensis Roxb. showed good inhibitory bioactivity against VEGF receptor-1 kinase （IC50：13.8 μg/mL）. In order to find new and bioactive compounds, the chemical constituents of the stem bark of F. chinensis were investigated and two new coumarins, namely 6＇-O-sinapinoyl esculin （compound 1） and 6＇-O-vanillyl esculin （compound 2）, together with eleven known compounds （compounds 3-13） were isolated. The structures of the two new compounds were identified by their physicochemical properties and spectral analysis, particularly one- and two-dimensional nuclear magnetic resonance spectral methods. The known compound, oleuropein （compound 11）, exhibited moderate activity （IC50：（8.7 ± 1.3） μmol/L） to inhibit VEGF receptor- 1 kinase.

关键词： coumarins Fraxinus chinensis VEGF receptor-1 kinase.

Chemistry and Process Optimization of V-Microalloyed N80-Class Seamless Casing Tube

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Journal of Iron and Steel Research International 2010年第3期17卷 72-78页

作者： PAN Tao YANG Cai-fu MA Yue XUE dong-mei zhang Yong-quan Division for Structural Materials Central Iron and Steel Research Institute Beijing 100081 China

The complex effects of different nitrogen （N） contents and thermal routines on the microstructure and mechanical properties of 33Mn2V steels for N80-Class seamless casing tube application were investigated using Gleeble simulation technique. The results showed that the N additions of 0. 014 %- 0. 021 % in the steels for the in-line normalization process （ILNP） increased the strength while the toughngss remained at a high level as compared with the steel with N content of 0. 005 %. It was also revealed that the N addition of 0. 021%could enhance the performance combination of strength and toughness in the steels by using 700 ℃ as the cooling interrupted temperature （CIT） for the non in-line normalizing process （NILNP）. It was further evidenced that the toughness was improved at expense of strength to some degree in all the steels by decreasing reheating temperature for the ILNP, while an increase of CIT for NILNP severely impaired the toughness and slightly improve the strength in the high-N steel with N content of 0. 021%. This can be attributed to the dissolution and precipitation behavior of V（C,N）. The optimization of V （C,N） precipitation could be achieved by enhancing N. The precipitation of V（C, N） in austenite was promoted by cooling to a certain temperature lower than the A,1 for the ILNP. The V（C,N） particles formed in austenite contrib- uted to grain refinement by the VN-induced nucleation of intragranular ferrite, but as a result the effect of precipitation on strengthening would become weaker due to a decrease of the precipitation of V in ferrite.

关键词： seamless tube in-line normalizing V-N microalloying reheating mechanical properties Gleeble simulation

A machine learning-based study of multifactor susceptibility and risk control of induced seismicity in unconventional reservoirs

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Petroleum Science 2023年第4期20卷 2232-2243页

作者： Gang Hui zhang-Xin Chen Hai Wang Zhao-Jie Song Shu-Hua Wang Hong-Liang zhang dong-mei zhang Fei Gu National Key Laboratory of Petroleum Resources and Engineering China University of PetroleumBeijing102249PR China Department of Chemical and Petroleum Engineering University of CalgaryCalgaryABT2N1N4Canada Eastern Institute for Advanced Study Ningbo315200ZhejiangPR China Computer Modeling Group Ltd.Calgary ABT2L2M1Canada CNOOC Research Institute Beijing100028PR China China University of Geoscience(Wuhan) Wuhan430074HubeiPR China Research Institute of Petroleum Exploration and Development Beijing10083PR China

A comprehensive dataset from 594 fracturing wells throughout the Duvernay Formation near Fox Creek, Alberta, is collected to quantify the influences of geological, geomechanical, and operational features on the distribution and magnitude of hydraulic fracturing-induced seismicity. An integrated machine learning-based investigation is conducted to systematically evaluate multiple factors that contribute to induced seismicity. Feature importance indicates that a distance to fault, a distance to basement, minimum principal stress, cumulative fluid injection, initial formation pressure, and the number of fracturing stages are among significant model predictors. Our seismicity prediction map matches the observed spatial seismicity, and the prediction model successfully guides the fracturing job size of a new well to reduce seismicity risks. This study can apply to mitigating potential seismicity risks in other seismicity-frequent regions.

关键词： Induced seismicity Hydraulic fracturing Seismicity susceptibility Risk control Machine learning

Co,K-Supported Hexagonal Mesoporous Silicas for Catalytic Oxidation of 4-t-Butyltoluene

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Chemical Research in Chinese Universities 2010年第4期26卷 622-625页

作者： YU Wei-hua ZHOU Chun-hui TONG dong-shen FANG mei zhang Bo Research Group for Advanced Materials ＆ Sustainable Catalysis（AMSC） College of Chemical Engineering and Materials Science Zhejiang University of Technology Hangzhou 310014 P R. China

Co,K-Supported hexagonal mesoporous silicas（HMS） have been prepared by incipient wetness impregnation with cobalt acetate tetrahydrate and potassium acetate as metal precursors, and ethylene glycol as impregnation solvent. The products have been characterized via powder X-ray diffraction, N2 adsorption-desorption isotherms and diffuse reflectance UV-Vis spectroscopy. The divalent cobalt with a tetrahedral oxygen coordination exists mainly in the calcined samples. The catalytic properties have been tested for the oxidation of 4-t-butyltoluene with dioxygen in liquid phase at mild conditions. The products offered good catalytic activities in the oxidation reactions. Co-K-HMS catalyst with loading 4% Co and 2% K（mass fraction） affords a higher yield（22.4%） of 4-t-butylbenzaldehyde at a conversion of 28.3% under the reaction conditions. Adding a proper amount of potassium in Co-HMS results in an improvement catalytic activity and stability.

关键词： Mesoporous silica Catalyst Cobalt Potassium Oxidation

Minimizing Ratio of Monotone Non-submodular Functions

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Journal of the Operations Research Society of China 2019年第3期7卷 449-459页

作者： Yi-Jing Wang Da-Chuan Xu Yan-Jun Jiang dong-mei zhang Department of Information and Operations Research College of Applied SciencesBeijing University of TechnologyBeijing 100124China School of Mathematics and Statistics Science Ludong UniversityYantai 264025ShandongChina School of Computer Science and Technology Shandong Jianzhu UniversityJinan 250101China

In this paper,we investigate the problem of minimizing the ratio of normalized non-negative monotone non-submodular set function f and normalized non-negative monotone set function *** take advantage of the greedy technique and get a per-formance guarantee depending on the generalized curvature and inverse generalized curvature of f,as well as the submodularity ratio of *** results generalize the works of Bai et al.(Algorithms for optimizing the ratio of submodular ***:Proceedings of the 33rd International Conference on Machine L earning,2016)and Qian et al.(Optimizing ratio of monotone set ***:Proceedings of the 26th International Joint Conference on Artificial Intelligence,2017).

关键词： Non-submodular Set functions Minimizing ratio Greedy algorithm

Observed response of maglev structure undercrossed by three shield tunnels in soft soil

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Underground Space 2022年第4期7卷 636-661页

作者： dong-mei zhang Xiao-Chuang Xie Zhong-Kai Huang Mao-Zhu Peng Hong-Xin Zhu Key Laboratory of Geotechnical and Underground Engineering Ministry of EducationTongji UniversityShanghai 200092China Department of Geotechnical Engineering College of Civil EngineeringTongji UniversityShanghai 200092China Centre for Offshore Foundation Systems University of Western Australia35 Stirling HighwayCrawleyPerthWA 6009Australia Shanghai Municipal Engineering Design Institute(Group)Co. Ltd.China

This paper investigates the response of a maglev structure to three under-crossing tunnels of the Shanghai Metro Line *** minimal distance between the tunnels and pile groups of the maglev structure is only 1.5 m,thus the deformations of the maglev structure are strictly controlled for the serviceability of the operating maglev *** displacements of maglev piers and ground settlements during different tunnelling stages are monitored with an automatic measuring *** on the observed data,the ground settlement trough and displacements of maglev piers caused by the three shield tunnelling procedures are analyzed and *** maximal ground settlement after the completion of the three tunnelling procedures is -43 *** operate the existing maglev safely,practical construction control methods are applied,including synchronous grouting,adjustment of the shield status,shield-advancing speed control,and stabilisation of the soil chamber *** these countermeasures,the tunnel-induced deformations of maglev piers are well below the predefined *** piers heave under the strict deformation criterion of 2.0 *** crossing project is finally completed without interruptions of the maglev operations by monitoring the *** presented project is a valuable example for the evaluation of shield tunnelling effects on the adjacent maglev structures and establishes criteria for similar projects in the future.

关键词： Maglev Multi-crossing Shield tunnelling Ground settlement Pier displacement