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Simulation and reconstruction of particle trajectories in the CEPC drift chamber

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Nuclear Science and Techniques 2024年第8期35卷 9-22页

作者： Meng‑Yao liu wei‑dong li Xing‑Tao Huang Yao Zhang Tao lin Ye Yuan Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China Institute of High Energy Physics Beijing 100049China University of Chinese Academy of Sciences Beijing 100049China

The circular electron-positron collider(CEPC)is designed to precisely measure the properties of the Higgs boson,study electroweak interactions at the Z-boson peak,and search for new physics beyond the Standard *** a component of the 4th conceptual CEPC detector,the drift chamber facilitates the measurement of charged *** study implemented a Geant4-based simulation and track reconstruction for the drift *** the simulation,detector construction and response were implemented and added to the CEPC simulation *** development of track reconstruction involves track finding using the combinatorial Kalman filter method and track fitting using the tool of *** the simulated data,the tracking performance was *** results showed that both the reconstruction resolution and tracking efficiency satisfied the requirements of the CEPC experiment.

关键词： CEPC Drift chamber Detector simulation Track reconstruction

Targeting colorectal cancer with Herba Patriniae and Coix seed:Network pharmacology,molecular docking,and in vitro validation

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3539-3558页

作者： Cheng-Lei Wang Bing-wei Yang Xin-Yan Wang Xue Chen wei-dong li Hao-Yu Zhai Ying Wu Mu-YaoCui Jia-He Wu Qing-Hui Meng Nan Zhang Department of Oncology Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing 100053China The First Clinical Medical College Shaanxi University of Chinese MedicineXianyang 712046Shaanxi ProvinceChina Department of Scientific Research Management Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing 100053China School of Clinical Medicine Qinghai University Xining 810000Qinghai ProvinceChina School of Chinese Materia Medica Beijing University of Chinese MedicineBeijing 100029China

BACKGROUND Herba Patriniae and Coix seed(HC)constitute a widely utilized drug combination in the clinical management of colorectal cancer(CRC)that is known for its diuretic,anti-inflammatory,and swelling-reducing *** its efficacy has been demonstrated in a clinical setting,the active compounds and their mechanisms of action in CRC treatment remain to be fully *** To identify the active,CRC-targeting components of HC and to elucidate the mechanisms of action *** Active HC components were identified and screened using *** for each component were ***-related targets were obtained from human gene *** targets between HC and CRC were identified.A“drug-ingredient-target”network was created to identify the core components and targets *** Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analyses were conducted to elucidate the key pathways *** docking between core targets and key components was *** vitro experiments validated core *** Nineteen active components of HC were identified,with acacetin as the primary active *** predictive analysis identified 454 targets of the active compounds in *** mapping with 2685 CRC-related targets yielded 171 intervention targets,including 30 core *** and KEGG analyses indicated that HC may influence the phosphoinositide 3-kinase(PI3K)/Akt signaling *** docking showed that acacetin exhibited an optimal interaction with AKT1,identifying PI3K,AKT,and P53 as key genes likely targeted by HC during CRC *** inhibited HT-29 cell proliferation and migration,as well as promoted apoptosis,in *** blotting analysis revealed increased p53 and cleaved caspase-3 expression and decreased levels of p-PI3K,p-Akt,and survivin,which likely contributed to CRC *** Acacetin,the principal active compound in the HC pair,inhibited the proliferati

关键词： Colorectal cancer Baijiangcao(Herba Patriniae) Yiyiren(Coix seed) Acacetin Proliferation Migration Apoptosis Network pharmacology

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谷神星一号运载火箭的时变模态参数辨识

振动工程学报 2024年第5期37卷 729-736页

作者：马志赛丁千刘百奇刘建设张军锋董威利天津大学机械工程学院天津300350 天津市非线性动力学与控制重点实验室天津300350 北京星河动力装备科技有限公司北京100176

针对运载火箭这一大型复杂系统,单纯依靠机理分析难以建立能够精确描述其时变特征的动力学模型,借助模态辨识技术获取其在飞行状态下的时变动力学特性尤为必要。面向运载火箭的飞行模态辨识需求,发展基于时变自回归滑动平均模型的仅输... 详细信息

针对运载火箭这一大型复杂系统,单纯依靠机理分析难以建立能够精确描述其时变特征的动力学模型,借助模态辨识技术获取其在飞行状态下的时变动力学特性尤为必要。面向运载火箭的飞行模态辨识需求,发展基于时变自回归滑动平均模型的仅输出递推辨识方法,引入指数加权遗忘机制进行时变特性跟踪,能够在激励未知的情况下仅基于响应数据准确快速辨识运载火箭的时变模态。以谷神星一号运载火箭为例,开展飞行遥测数据的快速处理,准确辨识发射准备阶段和飞行阶段的关键低阶时变模态,辨识结果与有限元分析结果的变化规律相互吻合,验证了所提时变模态仅输出递推辨识方法是有效可行的,服务了运载火箭有限元模型修正和姿控系统设计的实际工程需求。

关键词：运载火箭时变模态参数谷神星一号递推辨识

Current–phase relations of a ring-trapped Bose–Einstein condensate with a weak link

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Chinese Physics B 2019年第1期28卷 218-222页

作者： Xiu-Rong Zhang wei-dong li Institute of Theoretical Physics and Department of Physics State Key Laboratory of Quantum Optics and Quantum Optics DevicesCollaborative Innovation Center of Extreme OpticsShanxi UniversityTaiyuan 030006China

The current–phase relations of a ring-trapped Bose–Einstein condensate interrupted by a rotating rectangular barrier are extensively investigated with an analytical solution. A current–phase diagram, single and multi-valued relation, is presented with a rescaled barrier height and width. Our results show that the finite size makes the current–phase relation deviate a little bit from the cosine form for the soliton solution in the limit of a vanishing barrier, and the periodic boundary condition selects only the plane wave solution in the case of high barrier. The reason for multi-valued current–phase relation is given by investigating the behavior of soliton solution.

关键词： ring-trapped Bose–Einstein condensate weak link current–phase relation analytical solution

Radar target recognition based on micro-Doppler effect

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Optoelectronics Letters 2008年第6期4卷 456-459页

作者： dong wei-guang li Yan-jun College of Astronautics Northwestern Polytechnical University Xi ＇an 710072 China

Mechanical vibration of target structures will modulate the phase function of radar backscattering,and will induce the frequency modulation of returned signals from the target. It generates a side bands of the target body Doppler frequency shift,which is helpful for target recognition. Based on this,a micro-Doppler atomic storehouse is built for the target recognition,and four kinds of common classifiers are used separately to perform the classified recognition. The simulation experimental results show that this method has high recognition rate above 90%.

关键词：雷达目标显微多普勒效应信息处理后向散射

Prediction of blast furnace gas generation based on data quality improvement strategy

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Journal of Iron and Steel Research International 2023年第5期30卷 864-874页

作者： Shu-han liu Wen-qiang Sun wei-dong li Bing-zhen Jin Department of Energy Engineering School of MetallurgyNortheastern UniversityShenyang 110819LiaoningChina State Environmental Protection Key Laboratory of Eco-Industry(Northeastern University) Ministry of Ecology and EnvironmentShenyang 110819LiaoningChina State Key Laboratory of Metal Material for Marine Equipment and Application Anshan 114009LiaoningChina Ansteel Iron and Steel Research Institute Ansteel Group Corporation LimitedAnshan 114009LiaoningChina General Heavy Section Mill Angang Steel Company LimitedAnshan 114021LiaoningChina

The real-time energy flow data obtained in industrial production processes are usually of low *** is difficult to accurately predict the short-term energy flow profile by using these field data,which diminishes the effect of industrial big data and artificial intelligence in industrial energy *** real-time data of blast furnace gas(BFG)generation collected in iron and steel sites are also of low *** order to tackle this problem,a three-stage data quality improvement strategy was proposed to predict the BFG *** the first stage,correlation principle was used to test the sample *** the second stage,the original sample set was rectified and *** the third stage,Kalman filter was employed to eliminate the noise of the updated sample *** method was verified by autoregressive integrated moving average model,back propagation neural network model and long short-term memory *** results show that the prediction model based on the proposed three-stage data quality improvement method performs *** short-term memory model has the best prediction performance,with a mean absolute error of 17.85 m3/min,a mean absolute percentage error of 0.21%,and an R squared of 95.17%.

关键词： Blast furnace gas Iron and steel industry Data quality improvement Artificial intelligence Gas generation prediction

Dienone-phenol Rearrangement of C-9 Oxygenated Decalinic Dienone and Analogs through B-Ring Cleavage

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Chinese Chemical Letters 2003年第7期14卷 689-692页

作者： Jing Chun CHEN Gang ZHOU wei dong li Yu lin li National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry Lanzhou UniversityLanzhou 730000

Dehydrogenation of 9-hydroxy decalinic enones and analogs with DDQ resulted in a formal dienone-phenol type rearrangement via B-ring cleavage, while the corresponding dienone acetates underwent base-catalyzed formal d... 详细信息

关键词： Dienone-phenol rearrangement decalinic dienone dehydrogenation DDQ.

Auto-parametric resonance of a continuous-beam-bridge model under two-point periodic excitation:an experimental investigation and stability analysis

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 445-454页

作者： li Yuchun Shen Chao liu wei li dong Department of Hydraulic Engineering College of Civil EngineeringTongji UniversityShanghai 200092China

The auto-parametric resonance of a continuous-beam bridge model subjected to a two-point periodic excitation is experimentally and numerically investigated in this *** auto-parametric resonance experiment of the test model is conducted to observe and measure the auto-parametric resonance of a continuous beam under a two-point excitation on *** parametric vibration equation is established for the test model using the finite-element *** auto-parametric resonance stability of the structure is analyzed by using Newmark's method and the energy-growth exponent *** effects of the phase difference of the two-point excitation on the stability boundaries of auto-parametric resonance are studied for the test *** with the experiment,the numerical instability predictions of auto-parametric resonance are consistent with the test phenomena,and the numerical stability boundaries of auto-parametric resonance agree with the experimental *** a continuous beam bridge,when the ratio of multipoint excitation frequency(applied to the columns)to natural frequency of the continuous girder is approximately equal to 2,the continuous beam may undergo a strong auto-parametric *** with the present experiment and analysis,a hypothesis of Volgograd Bridge's serpentine vibration is discussed.

关键词： auto-parametric resonance continuous beam bridge model two-point excitation experimental investigation stability analysis vibration of Volgograd Bridge

Overexpression of a Foreign Bt Gene in Cotton Affects the Low-Molecular-weight Components in Root Exudates

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Pedosphere 2007年第3期17卷 324-330页

作者： YAN wei-dong SHI wei-Ming li Bao-Hai ZHANG Min State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences Nanjing210008 （China）

Most research in the past using genetically modified crops (GM crops) has focused on the ecological safety of foreign gene (i.e., the gene flow), gene products (for example, Bt (Bacillus thuringiensis) protein), and the safety of transgenic food for humans. In this study, changes in both the species and amounts of low-molecular-weight components in cotton (Gossypium hirsutum L.) root exudates after foreign Bt gene overexpression were investigated under different nutritional conditions. Transgenic cotton containing Bt (Bt-cotton), supplemented with all the mineral nutrients, secreted more organic acids than the wild-type cotton (WT). When nitrogen was removed from the full-nutrient solution, the amount of organic acids secretion of Bt-cotton was lesser than that of WT. The roots of the transgenic cotton secreted lesser amounts of amino acids and soluble sugars than the WT roots in the full-nutrient solution. Deficiencies of P and K caused a large increase in the total amino acid and soluble sugar secretions of both Bt-cotton and WT, with larger increases observed in Bt-cotton. Because transferring the foreign Bt gene into cotton can result in alterations in the components of the root exudates, with the effect varying depending on the nutritional status, the cultivation of genetically modified crops, such as Bt-cotton, in soil environments should be more carefully assessed, and the possible effects as a result of the alterations in the root exudate components should be considered.

关键词： gene overexpression low-molecular-weight components nutritional status root exudates transgenic cotton