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Complications of common bile duct stones: A risk factors analysis

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Hepatobiliary & Pancreatic Diseases International 2021年第4期20卷 361-365页

作者： dong Jun Oh Ji Hyung Nam dong Kee jang Jun Kyu Lee Department of Internal Medicine Dongguk University Ilsan HospitalGoyang 10326Korea

Background: The latest guidelines recommended that common bile duct stones(CBDSs) should be removed, preferably endoscopically, regardless of the presence of symptoms or complications. However, the removal of CBDSs may not be feasible in very old patients or those with co-morbidities. In these cases, it is important to understand the risk factors for the development of CBDSs-related complications to decide whether or not to treat high-risk patients. Herein, we aimed to identify the risk factors for the development of complications after the diagnosis of CBDSs. Methods: The medical records of patients with CBDSs between October 2005 and September 2019 were retrospectively analyzed. All patients with radiologically-diagnosed CBDSs, including those who received treatment and those who did not, were analyzed. Results: A total of 634 patients were included and 95(15.0%) patients had CBDS-related complications during the mean follow-up period of 32.6 months. Forty-four(6.9%) high-risk patients remained asymptomatic and did not receive treatment during the follow-up period. In multivariate analyses, size of CBDSs ≥ 5 mm and no treatment within 30 days were independent risk factors for the development of complications. The spontaneous passage of CBDSs was proved radiologically in 9 out of 81(11.1%) patients within 30 days. Conclusions: It is recommended treating CBDSs within 30 days from the diagnosis, even in high-risk patients, especially if the size is larger than 5 mm.

关键词： Common bile duct stone Risk factors Obstructive jaundice Pancreatitis Cholangitis

Influence of CaO on damping capacity and mechanical properties of Mg alloy

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中国有色金属学会会刊：英文版 2009年第B09期19卷 76-79页

作者： dong-in jang Jin-Kyu LEE Dae-Up KIM Shae-K KIM Advanced Material Division Korea Institute of Industrial Technology Hyudai Mobis

For developing cost effective damping Mg alloys with high damping capacity and better mechanical properties, the microstructures, the mechanical properties at room temperature and the damping capacity of Mg alloy adding CaO were investigated and compared with those of K1A alloy. CaO adding into pure Mg maintains the damping capacity and increases the ultimate tensile strength compared with those of pure Mg. Mg-CaO alloy can be regarded as cost-effective damping alloy with high damping and mechanical properties as well as with the advantages of improving oxidation and burning resistances.

关键词：阻尼能力力学性能镁合金氧化钙成本效益微观结构阻尼性能电阻合金

Self-Healing Microcapsule-Thickened Oil Barrier Coatings

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Research 2019年第1期2019卷 1196-1204页

作者： Alane Tarianna OLim Chenlong Cui Hee dong jang Jiaxing Huang Department of Materials Science and Engineering Northwestern UniversityEvanstonIllinois 60208USA Rare Metals Research Center Korea Institute of Geoscience and Mineral ResourcesDaejeon 305-350Republic of Korea

Low-viscosity oils could potentially act as self-healing barrier coatings because they can readily fow and reconnect to heal minor *** the same reason,however,they typically do not form stable coatings on metal *** viscosity helps to stabilize the oil coating,but it also slows down the healing ***,we report a strategy for creating highly stable oil coatings on metal surfaces without sacrifcing their remarkable self-healing ***-viscosity oil flms can be immobilized on metal surfaces using lightweight microcapsules as thickeners,which form a dynamic network to prevent the creep of the *** the coating is scratched,oil around the opening can rapidly fow to cover the exposed area,reconnecting the particle *** of these coatings as anticorrosion barriers is *** coatings can be easily applied on metal surfaces,including those with complex geometries,both in air or under water,and remain stable even in turbulent *** can protect metal in corrosive environments for extended periods of time and can self-heal repeatedly when scratched at the same *** a strategy may ofer efective mitigation of the dangerous localized corrosion aggravated by minor imperfections or damage in protective coatings,which are typically hard to prevent or detect,but can drastically degrade metal properties.

关键词： coating creep corrosion

Effect of thixoextrusion parameters on mechanical properties of 7003 Aluminum wrought alloy

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Rare Metals 2006年第z2期25卷 124-128页

作者： YOON Young-Ok jang dong-In JO Hyung-Ho KIM Young-Jig KIM Shae K Department of Advanced Material Engineering Sungkyunkwan University 300 Chunchun-dong Jangan-gu Suwon Gyunggi-do 440-746 KoreaAdvanced Material Center Korea Institute of Industrial Technology 7-47 Songdo-dong Yeonsu-gu Incheon 406-840 Korea Advanced Material Center Korea Institute of Industrial Technology 7-47 Songdo-dong Yeonsu-gu Incheon 406-840 Korea Department of Advanced Material Engineering Sungkyunkwan University 300 Chunchun-dong Jangan-gu Suwon Gyunggi-do 440-746 Korea

The processing of high strength Al wrought alloys does lead either to restrictions for geometrical complexity or to high production costs due to low productivity and multiple-step processes. Thixoextrusion process to overcome these difficulties has been under investigation. In the present study, the effect of thixoextrusion parameters was investigated on mechanical properties of 7003 Al wrought alloy. The maximum extrusion pressure of the thixoextrusion process is three times lower than that of the hot extrusion process. The elongated grains which have the axisymmetry with extrusion direction are generally observed during hot extrusion process, while the microstructures of the thixoextruded are isotropic. The tensile and yield strengthes of the thixoextruded bar are lower than those of the hot extruded bar, while the elongation value of the thixoextruded bar is higher than that of the hot extruded bar.

关键词： thixoextrusion isotropy 7003 Al wrought alloy

Effect of natural extract eye drops in dry eye disease rats

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International Journal of Ophthalmology(English edition) 2020年第7期13卷 1023-1030页

作者： Soo Youn Choi Youngsub Eom Jee Yong Kim dong Hoon jang Jong Suk Song Hyo Myung Kim Department of Ophthalmology Korea University College of MedicineSeoul 02841Republic of Korea BGN World Tower Eye Clinic Seoul 05551Republic of Korea Department of Ophthalmology Korea University Ansan HospitalKorea University College of MedicineGyeonggi-do 15355Republic of Korea Medical O Co. Ltd.Seoul 06025Republic of Korea

AIM:To investigate the therapeutic effect of natural extract eye drops containing bee venom,musk,and deer antlers in dry eye disease(DED)animal ***:Scopolamine-injected DED rats and lacrimal gland-excised rats were allocated into control,saline,and natural extract groups respectively and a normal group(lacrimal gland excision was not performed)in lacrimal gland-excised *** eye drop instillation 4 times a day for 5 d,corneal fluorescein staining(CFS)scores,tear MUC5AC levels,and tear lactic dehydrogenase(LDH)levels were ***:In scopolamine-injected rats,the natural extract-treated group had significantly lower CFS scores(1.7±0.5,4.7±1.4,3.8±1.9,P=0.006)and tear LDH levels(0.10±0.01,0.19±0.01,0.16±0.08 OD,P=0.014)but higher tear MUC5AC levels(12.9±3.7,7.9±2.0,9.7±3.6 ng/m L,P=0.041)compared with the control and saline-treated *** were no significant differences between the control and saline-treated *** lacrimal gland-excised rats,the natural extract-treated group also had lower CFS scores(4.3±1.2,11.5±2.3,9.0±1.9,P<0.001,P=0.001)and tear LDH levels(0.30±0.08,0.48±0.12,0.39±0.05 OD,P<0.05)but higher tear volume(4.3±0.9,1.9±0.7,2.8±1.1 mm,P=0.005,P=0.124)and tear MUC5 AC levels(8.2±2.0,2.9±1.2,5.4±2.2 ng/m L,P<0.001,P=0.047)compared with the control and saline-treated *** were no significant differences in the CFS scores,tear MUC5AC level,and tear LDH level between the normal and natural extracttreated ***:The natural extract consisting of bee venom,musk,and deer antlers may have effectiveness in DED treatment by restoring the damaged ocular surface,increasing tear volume,and recovering the tear mucin layer in DED rats.

关键词： bee venom musk deer antler natural extract dry eye disease rat

Endoscopic bilateral stent-in-stent placement for malignant hilar obstruction using a large cell type stent

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Hepatobiliary & Pancreatic Diseases International 2016年第6期15卷 633-639页

作者： Jin Myung Park Sang Hyub Lee Kwang Hyun Chung dong Kee jang Ji Kon Ryu Yong-Tae Kim Jae Min Lee Woo Hyun Paik Department of Internal Medicine and Liver Research Institute Seoul National University HospitalSeoul National University College of Medicine Department of Internal Medicine Kangwon National University HospitalKangwon National University School of Medicine Department of Internal Medicine Gyeongsang National University HospitalGyeongsang National University College of Medicine Department of Internal Medicine Inje University Ilsan Paik Hospital

BACKGROUND： Bilateral stent-in-stent （SIS） self-expandable metal stent placement is technically chghallenging for palliation of unresectable malignant hilar obstruction. In the SIS technique, the uniform large cell type biliary stent facilitates contralateral stent deployment through the mesh of the first metallic stent. This study aimed to assess the technical success and clinical effectiveness of this technique with a uniform large cell type biliary stent. METHODS： Thirty-one patients who underwentlbilateral SIS placement using a large cell type stent were reviewed retrospectively. All patients showed malignant hilarl obstruction （Bismuth types Ⅱ, Ⅲ, Ⅳ） with different etiologies. RESULTS： Sixteen （51.6%） patients were male. The mean age of the patients was 67.0±14.0 years. Most patients were diagnosed as having hilar cholangiocarcinoma （58.1%） and gallbladder cancer （29.0%）. Technical success rate was 83.9%. Success was achieved more frequently in patients without masses obstructing the biliary confluence （MOC） than those with MOC （95.2% vs 60.0%, P=0.03）. Functional success rate was 77.4%. Complications occurred in 29.0% of the patients. These tended to occur more frequently in patients with MOC （50.0% vs 19.0%, P=0.11）. Median time to recurrent biliary obstruction was 188 days and median survival was 175 days. CONCLUSIONS： The large cell type stent can be used efficiently for bilateral SIS placement in malignant hilar obstruction. However, the risk of technical failure increases in patients with MOC, and caution is needed to prevent complications for these patients.

关键词： biliary tract disease cholangiocarcinoma endoscopic biliary drainage stent insertion

Comparison of cytological and histological preparations in the diagnosis of pancreatic malignancies using endoscopic ultrasoundguided fine needle aspiration

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Hepatobiliary & Pancreatic Diseases International 2017年第4期16卷 418-423页

作者： dong Kee jang Sang Hyub Lee Jun Kyu Lee Woo Hyun Paik Kwang Hyun Chung Ban Seok Lee Jun Hyuk Son Jae Woo Lee Ji Kon Ryu Yong-Tae Kim Kyoung-Bun Lee Department of Internal Medicine Dongguk University Ilsan Medical CenterGoyang-siGyeonggi-doKorea Department of Internal Medicine and Liver Research Institute Seoul National University HospitalSeoul National University College of MedicineSeoulKorea Department of Internal Medicine Inje University Ilsan Paik HospitalGoyang-siGyeonggi-doKorea Department of Pathology Seoul National University College of MedicineSeoulKorea

BACKGROUND:Endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) has become a crucial diagnostic technique for pancreatic *** specimen obtained by EUS-FNA can be prepared for either cytological or histological *** study was to compare diagnostic performance of cytological and histological preparations using EUSFNA in the same lesions when pancreatic malignancies were ***:One hundred and eighteen patients who underwent EUS-FNA for suspected pancreatic malignancies were consecutively *** procedures were conducted by a single echoendoscopist under the same *** adequate preparations were obtained by 22-gauge needles with 20 to-and-fro movements for each *** 4 preparations included 2 cytological and 2 histological *** pathologic reviews of all specimens were conducted independently by a single experienced ***,specificity,and accuracy of the 2 preparations were ***:The enrolled patients consisted of 62 males(52.5%),with the mean age of 64.6±10.5 *** was performed in 23(19.5%) *** hundred and sixteen(98.3%) lesions were classified as malignant,while 2(1.7%) were *** of cytology and histology were 87.9% and 81.9%,respectively,with no significant difference(P=0.190).Accuracy was also not significantly *** preparation was more sensitive when the size of lesion was <3 cm(86.7% vs 68.9%,P=0.033).CONCLUSIONS:Our results suggested that the diagnostic performances of cytological and histological preparations are not significantly different for the diagnosis of pancreatic ***,cytological preparation might be more sensitive for pancreatic lesions <3 cm.

关键词： endoscopic ultrasound-guided fine needle aspiration pancreatic neoplasms cytology pathology histology

Electroacupuncture for abdominal pain relief in patients with acute pancreatitis:A three-arm randomized controlled trial

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Journal of Integrative Medicine 2023年第6期21卷 537-542页

作者： dong Kee jang Jun Kyu Lee Chan Yung Jung Kyung Ho Kim Ha Ra Kang Yeon Sun Lee Jong Hwa Yoon Kwang Ro Joo Min Kyu Chae Yong Hyeon Baek Byung-Kwan Seo Sang Hyub Lee Chiyeon Lim Department of Internal Medicine Seoul Metropolitan Government Boramae Medical CenterSeoul National University College of MedicineSeoul 07061Republic of Korea Department of Internal Medicine Dongguk University Ilsan HospitalDongguk University College of MedicineGoyang 10326Republic of Korea Department of Acupuncture and Moxibustion Dongguk University Ilsan Oriental HospitalCollege of Korean MedicineDongguk UniversityGoyang 10326Republic of Korea Department of Korean Medicine Dongguk UniversityGoyang 10326Republic of Korea Department of Acupuncture and Moxibustion College of Korean MedicineDongguk UniversityGyeongju 38067Republic of Korea Department of Gastroenterology Kyung Hee University Hospital at GangdongSeoul 05278Republic of Korea Department of Acupuncture and Moxibustion Kyung Hee University Korean Medicine Hospital at GangdongSeoul 05278Republic of Korea Department of Internal Medicine and Liver Research Institute Seoul National University HospitalSeoul National University College of MedicineSeoul 03080Republic of Korea Department of Biostatistics College of MedicineDongguk UniversityGoyang 10326Republic of Korea

Background: Electroacupuncture(EA) may reduce the severity of acute pancreatitis(AP) and provide additional pain relief in patients with chronic pancreatitis. However, the ability of EA to relieve pain in patients with AP has not been well ***: This study was undertaken to compare the pain-relieving effects of EA and conventional treatment in patients with ***, setting, participants and interventions: This study was conducted using a randomized, controlled,three-arm, parallel-group and multi-center design. Patients diagnosed with AP were randomly and equally assigned to EA1, EA2 or control groups. All participants received conventional standard-of-care therapy for AP. Local EA alone was administered in EA1, and local plus distal EA was given in *** EA included two abdominal acupoints, while distal EA included twelve peripheral acupoints. EA groups underwent one session of EA daily for 4 days(days 1–4), or until pain was resolved or *** outcome measures: The primary outcome measure was the change in the visual analogue scale(VAS;0–100) pain score between baseline and day ***: Eighty-nine participants were randomized into EA1, EA2 and control groups, and 88(EA1, 30;EA2, 29;control, 29) were included in the full-analysis set. VAS score change(median [interquartile range]) on day 5 was(12.3 ± 22.5) in the EA1 group,(10.3 ± 21.5) in the EA2 group, and(8.9 ± 15.2) in the control group. There were not significant differences in the change in VAS score among treatments(P = 0.983). However, time to food intake was significantly shorter in the EA group(EA1 + EA2) than in the control group(median 2.0 days vs 3.0 days), with a hazard ratio of 0.581(P = 0.022;95% CI,0.366–0.924). No significant adverse events ***: EA treatment did not significantly reduce pain after 4 days of treatment in patients with AP-associated abdominal pain but significantly reduced time to first food intake.

关键词： Acute pancreatitis Electroacupuncture Pain management Abdominal pain Randomized controlled trial

Winter and spring nighttime warming acclimation improves the grain yield of winter wheat via enhancing the flag leaf photosynthetic performance in the Yangtze River Basin of China

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Winter and spring nighttime warming acclimation improves the...