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Regularization of mathematical model for chip flow angle catastrophe

Advances in Manufacturing 2021年第4期9卷 568-579页

作者： shao-Nan Zhang dong-dong Cheng Liang-Shan Xiong School of Mechanical Science and Engineering Huazhong University of Science and TechnologyWuhan 430074People’s Republic of China

The chip flow angle(CFA)catastrophe in double-edged cutting results in a significant reduction in the cutting force,which can benefit the ***,established potential functions(i.e.,cutting power calculation functions)of mathematical models for the CFA catastrophe are presented in the form of transcendental functions with two control parameters and one state parameter,which are extremely complex.A method is proposed herein to realize the regularization of the potential functions and establish mathematical models in a standard form and with complete content for the CFA *** this method,the potential function of the CFA catastrophe is expanded into a k-order Taylor polynomial at each midpoint of N end-to-end equally partitioned intervals of the state parameter using the Taylor function provided in *** potential function after piecewise Taylor expansion is transformed into the same form as the potential function of the standard cusp catastrophe model by truncating the first five terms of the Taylor polynomial and eliminating the third-order term of the state parameter with elementary ***,the regularization of potential function is ***,the regularization of equilibrium surface and bifurcation set can be realized based on the conclusions of the catastrophe *** errors of the potential function,equilibrium surface,and bifurcation set are defined to evaluate the effectiveness of this regularization *** problem of calculating regularization errors is regarded as an optimization ***‘‘simulannealbnd’’function provided in MATLAB is used to solve the *** the proposed method,the regularization of a mathematical model for the CFA catastrophe established by the predecessor is completed;a mathematical model(i.e.,standard cusp catastrophe model)in a standard form and with complete content for the CFA catastrophe is established;and the corresponding regularization errors

关键词： Chip flow angle(CFA)catastrophe Mathematical model Regularization Potential function Catastrophe theory Cusp catastrophe model

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Development of Single-Molecule Magnets

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Chinese Journal of Chemistry 2020年第9期38卷 1005-1018页

作者： dong shao Xin-Yi Wang State Key Laboratory of Coordination Chemistry Collaborative Innovation Center of Advanced MicrostructuresSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjingJiangsu 210023China

Single-molecule magnets(SMMs)are paramagnetic molecules that can be magnetized below a certain temperature and have potential applications in high-density information storage,magnetic-qubits,spintronic devices,*** discovery of the first SMM,Mn12,opened a new era of molecular magnetism and promoted collaborative researches between chemists and physicists for their exotic quantum as well as classical magnetic *** the recent past,great efforts have been madefto develop strategies for constructing new SMMs with high energy barriers(Ueff)and blocking temperatures(Tb), resulting in great and fast development of *** this concise review,we highlight the main synthetic approaches and representative results in the design and synthesis of high *** hope to give the readers a basic understanding of SMMs and a snapshot of the representative researches on SMMs from a perspective of synthetic chemists.

关键词： properties. magnets constructing

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AN ANISOTROPIC NONCONFORMING FINITE ELEMENT WITH SOME SUPERCONVERGENCE RESULTS

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Journal of Computational Mathematics 2005年第3期23卷 261-274页

作者： dong-yangShi Shi-pengMao shao-chunChen DepartmentofMathematics ZhengzhouUniversityZhenzhou450052China

The main aim of this paper is to study the error estimates of a nonconforming finite element with some superconvergence results under anisotropic meshes. The anisotropic interpolation error and consistency error estimates are obtained by using some novel approaches and techniques, respectively. Furthermore, the superclose and a superconvergence estimate on the central points of elements are also obtained without the regularity assumption and quasi-uniform assumption requirement on the meshes. Finally, a numerical test is carried out, which coincides with our theoretical analysis.

关键词： anisotropic meshes nonconforming finite element interpolation error andconsistency error estimates superclose superconvergence

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THREE DIMENSION QUASI-WILSON ELEMENT FOR FLAT HEXAHEDRON MESHES

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Journal of Computational Mathematics 2004年第2期22卷 178-187页

作者： shao-chunChen dong-yangShi Guo-biaoRen DepartmentofMathematics ZhengzhouUniversityZhengzhou450002China

The well known Wilson's brick is only convergent for regular cuboid meshes. In this paper a quasi-Wilson element of three dimension is presented which is convergent for any hexahedron meshes. Meanwhile the element is ... 详细信息

关键词： Anisotropic convergence Nonconforming element Three dimension Quasi-Wilson element

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Interaction of major facilitator superfamily domain containing 2A with the blood-brain barrier

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Neural Regeneration Research 2025年第8期20卷 2133-2152页

作者： Yilun Ma Taiwei dong Fei Luan Juanjuan Yang Feng Miao Peifeng Wei College of Pharmacy and First Clinical Medical College Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina National Drug Clinical Trial Agency The Second Affiliated Hospital of Shaanxi University of Chinese Medicine/Xixian New District Central HospitalXi′anShaanxi ProvinceChina

The functional and structural integrity of the blood-brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms underlying the formation and function of the blood-brain barrier remain poorly *** major facilitator superfamily domain containing 2A has been identified as a key regulator of blood-brain barrier *** plays a critical role in promoting and maintaining the formation and functional stability of the blood-brain barrier,in addition to the transport of lipids,such as docosahexaenoic acid,across the blood-brain ***,an increasing number of studies have suggested that major facilitator superfamily domain containing 2A is involved in the molecular mechanisms of blood-brain barrier dysfunction in a variety of neurological diseases;however,little is known regarding the mechanisms by which major facilitator superfamily domain containing 2A affects the blood-brain *** paper provides a comprehensive and systematic review of the close relationship between major facilitator superfamily domain containing 2A proteins and the blood-brain barrier,including their basic structures and functions,cross-linking between major facilitator superfamily domain containing 2A and the blood-brain barrier,and the in-depth studies on lipid transport and the regulation of blood-brain barrier *** comprehensive systematic review contributes to an in-depth understanding of the important role of major facilitator superfamily domain containing 2A proteins in maintaining the structure and function of the blood-brain barrier and the research progress to *** will not only help to elucidate the pathogenesis of neurological diseases,improve the accuracy of laboratory diagnosis,and optimize clinical treatment strategies,but it may also play an important role in prognostic *** addition,the effects of major facilitator superfamily domain containing 2A on blood-brain barrier lea

关键词： blood-brain barrier(BBB) caveolin-1 central nervous system docosahexaenoic acid endothelial cells lysophosphatidylcholine major facilitator superfamily domain containing 2A(MFSD2A) transcytosis

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Force and impulse multi-sensor based on flexible gate dielectric field effect transistor

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 214-220页

作者： Chao Tan Junling Lü Chunchi Zhang dong Liang Lei Yang Zegao Wang College of Materials Science and Engineering Sichuan UniversityChengdu 610065China The 54th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050081China

Nowadays,force sensors play an important role in industrial production,electronic information,medical health,and many other ***-dimensional material-based filed effect transistor(2D-FET)sensors are competitive with nano-level size,lower power consumption,and accurate ***,few of them has the capability of impulse detection which is a path function,expressing the cumulative effect of the force on the particle over a period of *** we fabricated the flexible polymethyl methacrylate(PMMA)gate dielectric MoS_(2)-FET for force and impulse sensor *** systematically investigated the responses of the sensor to constant force and varying forces,and achieved the conversion factors of the drain current signals(I_(ds))to the detected impulse(I).The applied force was detected and recorded by I_(ds)with a low power consumption of~30 *** sensitivity of the device can reach~8000%and the 4×1 sensor array is able to detect and locate the normal force applied on ***,there was almost no performance loss for the device as left in the air for two months.

关键词： flexible gate dielectric transistor force sensor impulse sensor force sensor array

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Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury

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Neural Regeneration Research 2025年第5期20卷 1416-1430页

作者： Mou Gao Qin dong Dan Zou Zhijun Yang Lili Guo Ruxiang Xu Department of Neurosurgery Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Department of Neurosurgery Chinese PLA General HospitalBeijingChina Department of Neurology Fu Xing HospitalCapital Medical UniversityBeijingChina

Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and *** previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological ***,the mechanism of CXCR4 upregulation in induced neural stem cells remains *** this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 ***,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial *** agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury ***,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head *** conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neura

关键词： Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell microglia neuroinflammation

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Microstructural evolution during the progressive transformation-induced plasticity effect in a Fe-0.1C-5Mnmedium manganese steel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 369-379页

作者： Mei Zhang Wenhao Li Yangfei Chen Yang Jiang Xiaofei Guo Han dong School of Materials Science and Engineering Shanghai UniversityShanghai 200444China State Key Laboratory of Advanced Special Steel Shanghai UniversityShanghai 200444China

The microstructural evolution of a cold-rolled and intercritical annealed medium-Mn steel(Fe-0.10C-5Mn)was investigated during uniaxial tensile ***-situ observations under scanning electron microscopy,transmission electron microscopy,and X-ray diffraction analysis were conducted to characterize the progressive transformation-induced plasticity process and associated fracture initiation *** findings were discussed with the local strain measurements via digital image *** results indicated that Lüders band formation in the steel was limited to 1.5%strain,which was mainly due to the early-stage martensitic phase transformation of a very small amount of the less stable large-sized retained austenite(RA),which led to localized stress concentrations and strain hardening and further retardation of *** small-sized RA exhibited high stability and progressively transformed into martensite and contributed to a stably extended Portevin-Le Chatelier *** volume fraction of RA gradually decreased from 26.8%to 8.2%prior to *** the late deformation stage,fracture initiation primarily occurred at the austenite/martensite and ferrite/martensite interfaces and the ferrite phase.

关键词： medium-Mn steel retained austenite progressive transformation-induced plasticity effect local strain fracture initiation

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Potato late blight caused by Phytophthora infestans:From molecular interactions to integrated management strategies

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Journal of Integrative Agriculture 2022年第12期21卷 3456-3466页

作者： dong Suo-meng ZHOU shao-qun Key Laboratory of Integrated Management of Crop Diseases and Pests Ministry of Education/Department of Plant Pathology and Key Laboratory of Plant ImmunityNanjing Agricultural UniversityNanjing 210095P.R.China Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120P.R.China

Over 170 years after the infamous Irish Potato Famine,potato late blight(PLB)caused by Phytophthora infestans remains the single most devastating disease of global potato production,causing up to 10 billion USD in yield loss and management *** decades of research,growers and agronomists in the field as well as laboratory scientists have made significant progress in understanding the molecular pathogenesis process of this critical pathosystem and effective management strategies to control ***,the need to feed an ever-increasing global population under changing climate demands continued improvement in efficient and sustainable PLB management schemes that can be implemented across a broad economic *** this review,we briefly summarize the current understanding of the molecular interaction between *** and its host plants,highlight the current integrated pest management strategy to control PLB on local and continental scales,and discuss the potential of further improvement of sustainable PLB control through genetic enhancement of crop resistance and emerging crop protection technologies.

关键词： potato late blight Phytophthora infestans integrated pest management

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A SIMPLE ITERATIVE ALGORITHM FOR MAXCUT

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Journal of Computational Mathematics 2024年第5期42卷 1277-1304页

作者： Sihong shao dong Zhang Weixi Zhang CAPT LMAM and School of Mathematical SciencesPeking UniversityBeijing 100871China LMAM and School of Mathematical Sciences Peking UniversityBeijing 100871China

We propose a simple iterative(SI)algorithm for the maxcut problem through fully using an equivalent continuous *** does not need rounding at all and has advantages that all subproblems have explicit analytic solutions,the cut values are monotonically updated and the iteration points converge to a local optima in finite steps via an appropriate subgradient *** experiments on G-set demonstrate the *** particular,the ratios between the best cut values achieved by SI and those by some advanced combinatorial algorithms in[***.,248(2017),365-403]are at least 0.986 and can be further improved to at least 0.997 by a preliminary attempt to break out of local optima.

关键词： Maxcut Iterative algorithm Exact solution Subgradient selection Fractional programming

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