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Development of a data collection and management system in West Africa:challenges and sustainability

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Infectious Diseases of Poverty 2018年第1期7卷 1300-1313页

作者： j.ffrey G.Shaffer Seydou O.Doumbia Daouda Ndiaye Ayouba Diarra j.les F.Gomis Davis Nwakanma Ismaela Abubakar Abdullahi Ahmad Muna Affara Mary Lukowski Clarissa Valim j.mes C.Welty Frances j.Mather j.seph Keating donald j.Krogstad Departments of Biostatistics(1440 Canal St. Suite 1610)and Tropical Medicine(#83171430 Tulane AvenueJ.B.Johnston BuildingRoom 510)New OrleansLA 70112-2699USA University of the Sciences Techniques and Technologies of BamakoBamakoMali University Cheikh Anta Diop DakarSenegal Medical Research Council Unit FajaraThe Gambia ScienceTRAX LLC MaconGAUSA Harvard T.H.Chan School of Public Health BostonMAUSA

Background:Developing and sustaining a data collection and management system(DCMS)is difficult in malariaendemic countries because of limitations in internet bandwidth,computer resources and numbers of trained *** premise of this paper is that development of a DCMS in West Africa was a critically important outcome of the West African International Centers of Excellence for Malaria *** purposes of this paper are to make that information available to other investigators and to encourage the linkage of DCMSs to international research and Ministry of Health data systems and ***:We designed and implemented a DCMS to link study sites in Mali,Senegal and The *** system was based on case report forms for epidemiologic,entomologic,clinical and laboratory aspects of plasmodial infection and malarial disease for a longitudinal cohort study and included on-site training for Principal Investigators and Data *** on this experience,we propose guidelines for the design and sustainability of DCMSs in environments with limited resources and ***:From 2012 to 2017,we performed biannual thick smear surveys for plasmodial infection,mosquito collections for anopheline biting rates and sporozoite rates and year-round passive case detection for malarial disease in four longitudinal cohorts with 7708 individuals and 918 households in Senegal,The Gambia and *** challenges included the development of uniform definitions and reporting,assessment of data entry error rates,unstable and limited internet access and software and technology *** included entomologic collections linked to longitudinal cohort studies,on-site data centres and a cloud-based data ***:At a time when research on diseases of poverty in low and middle-income countries is a global priority,the resources available to ensure accurate data collection and the electronic availability of those data remain severely limited.

关键词： Data collection Data(database)management system Diseases of poverty Malaria Plasmodium falciparum

Observation and modelling of snow and sea ice mass balance and its sensitivity to atmospheric forcing during spring and summer 2007 in the Central Arctic

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Advances in Polar Science 2021年第4期32卷 312-326页

作者： Bin CHENG Timo VIHMA Timo PALO Marcel NICOLAUS Sebastian GERLAND Laura RONTU j.ri HAAPALA donald PEROVICH Finnish Meteorological Institute Helsinki Fi-00101Finland University of Tartu 50090 TartuEstonia Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research BremerhavenGermany Norwegian Polar Institute Fram CentreTromsøNorway Thayer School of Engineering Dartmouth College HanoverNew HampshireUSA

Snow depth and sea ice thickness were observed applying an ice mass balance buoy(IMB)in the drifting ice station Tara during the International Polar Year in *** in situ observations on meteorological variables and surface fluxes were taken during May to *** this study,the operational analyses and short-term forecasts from two numerical weather prediction(NWP)models(ECMWF and HIRLAM)were extracted for the Tara drift *** compared the IMB,meteorological and surface flux observations against the NWP products,also applying a one-dimensional thermodynamic sea ice model(HIGHTSI)to calculate the snow and ice mass balance and its sensitivity to atmospheric *** modelled snow depth time series,controlled by NWP-based precipitation,was in line with the observed *** reproduced well the snowmelt onset,the progress of the melt,and the first date of snow-free *** performed well also in the late August freezing *** remain to model the“false bottom”observed during the melting *** evolution of the vertical temperature profiles in snow and ice was better simulated when the model was forced by in situ observations instead of NWP *** the melting period,the nonlinear ice temperature profile was successfully modelled with both forcing *** spring and the melting season,total sea ice mass balance was most sensitive to uncertainties in NWP results for the downward longwave radiation,followed by the downward shortwave radiation,air temperature,and wind speed.

关键词： Arctic snow melt sea ice mass balance snow on sea ice NWP models

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采用压缩感知的阵列失效单元诊断方法

西安电子科技大学学报 2018年第2期45卷 160-165页

作者：李玮邓维波杨强索莹 MIGLIORE Marco donald 哈尔滨工业大学电子与信息工程学院黑龙江哈尔滨150001 信息感知技术协同创新中心黑龙江哈尔滨150001 意大利卡西诺大学电信与信息工程学院意大利卡西诺03043

针对现有阵列单元故障诊断方法随阵元数目增多而存在的采样数量大、诊断时间长、计算复杂度高等缺陷,提出了一种采用压缩感知理论的故障诊断方法.该方法基于故障单元数目固有的稀疏性,利用完好阵列和实际阵列激励的差值构造稀疏信号.根... 详细信息

针对现有阵列单元故障诊断方法随阵元数目增多而存在的采样数量大、诊断时间长、计算复杂度高等缺陷,提出了一种采用压缩感知理论的故障诊断方法.该方法基于故障单元数目固有的稀疏性,利用完好阵列和实际阵列激励的差值构造稀疏信号.根据目标方位信息设计测量矩阵的网格划分准则,并通过测量矩阵以随机欠采样方式获取少量测量数据.结合平行坐标下降算法对该稀疏信号进行精确重构,从而实现故障单元的准确诊断.理论分析和仿真实验表明,文中提出的方法不仅明显减少了采样数量,有效缩短了诊断时间,大幅降低了计算复杂度,而且进一步提高了故障信息的重构精度.

关键词：阵列诊断压缩感知傅里叶变换子矩阵稀疏恢复迭代收缩算法

A chromosome-level genome assembly for Chinese plum‘Wushancuili'reveals the molecular basis of its fruit color and susceptibility to rain-cracking

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Horticultural Plant j.urnal 2024年第3期10卷 672-688页

作者： Kun Zhou j.ngwen Wang Lin Pan Fang Xiang Yi Zhou Wei Xiong Ming Zeng donald Grierson Wenbin Kong Lingyu Hu Wanpeng Xi College of Horticulture and Landscape Architecture Southwest UniversityChongqing 400715China Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River(Ministry of Education) Southwest UniversityChongqing 400715China Department of Pomology Chongqing Agricultural Technology Extension StationChongqing 401420China Plant and Crop Sciences Division School of BiosciencesUniversity of NottinghamSutton Bonington CampusLoughborough LE125RDUK Wuxi Economical Crop Technology Extension Station Chongqing 405800China

Chinese plum(Prunus salicina Lindl.)originates from China and makes a large contribution to the global production of *** ***‘Wushancuili'has a green coloration and high fruit quality and is economically important in eliminating poverty and protecting ecology in the Yangtze River Three Gorges ***,rain-induced cracking(rain-cracking,literally skin cracking caused by rain)is a limitation to‘Wushancuili'fruit production and causes severe *** study reported a high-quality‘Wushancuili'genome assembly consisting of a 302.17-Mb sequence with eight pseudo-chromosomes and a contig N50 of 23.59 Mb through the combination of Illumina sequencing,Pacific Biosciences HiFiⅢsequencing,and high-throughput chromosome conformation capture technology.A total of 25109 protein-coding genes are predicted and 54.17%of the genome is composed of repetitive sequences.‘Wushancuili'underwent a remarkable orthoselection during *** identification revealed that loss-of-function in four core MYB10 genes results in the anthocyanin deficiency and absence of red color,revealing the green coloration due to the residual high chlorophyll in fruit ***,the occurrence of cracking is assumed to be closely associated with cell wall modification and frequently rain-induced pathogen enrichment through transcriptomic *** loss of MYB10 genes might render fruit more susceptible to pathogen-mediated cracking by weakening the epidermal strength and reactive oxygen species(ROS)*** findings provided fundamental knowledge regarding fruit coloration and rain-cracking and will facilitate genetic improvement and cultivation management in Chinese plums.

关键词： Chinese plum Fruit coloration Fruit epidermis Genome MYB10 Rain-cracking

N<sup>ω</sup>-Nitro-N<sup>ω’</sup>-Substituted Guanidines: A Simple Class of Nitric Oxide Synthase Inhibitors

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Modern Research in Inflammation 2014年第2期3卷 48-58页

作者： Christophe D. Guillon David D. Wisnoski j.ya Saxena Ned D. Heindel Diane E. Heck donald j. Wolff j.ffrey D. Laskin Department of Chemistry Lehigh University Bethlehem USA Department of Environmental and Occupational Medicine Rutgers University—Robert Wood Johnson Medical School Piscataway USA Department of Environmental Health Science New York Medical College Valhalla USA Department of Pharmacology Rutgers University—Robert Wood Johnson Medical School Piscataway USA

A series of Nω-nitro-Nω’-substituted guanidines has been prepared as potential inhibitors of the human Nitric Oxide Synthase (NOS) isoforms. The reported utility of amino-guanidine and nitroarginine in iNOS inhibition points to a potential similar utility for analogs of nitro-guanidine. The compound library was tested against the three isoforms of Nitric Oxide Synthase (eNOS, iNOS and nNOS). Several candidates showed excellent activity and good selectivity for nNOS. One particular compound even demonstrated good selectivity for iNOS. The potential usefulness of such selective inhibitors is discussed.

关键词： Nitro-Guanidines Nitric Oxide Synthase (NOS) Isoforms Selective Inhibitors

非线性双曲型积分微分方程有限元逼近的误差分析

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山东大学学报（理学版） 2001年第2期36卷 161-170页

作者： MBAZI Donatien donald(窦纳) 山东大学数学与系统科学学院山东济南250100

考虑非线性双曲型积分微分方程半离散有限格式 ,得到H1超收敛和最优阶L∞ 和Wl,∞ 模误差估计 .

关键词：非线性双曲积分微方程半离散有限元超收敛最大模最优阶误差估计

The Cerebral Blood Flow Correlates of Emotional Facial Processing in Mild Alzheimer's Disease

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Neuroscience & Medicine 2011年第1期2卷 6-13页

作者： Roger T. Staff Trevor S. Ahearn Louise H. Phillips Clare Scott donald Mowat Claude Wischik Lawrence j. Whalley Alison D. Murray 不详

Deficits in facial emotion processing are features of mild Alzheimer’s disease (AD). These impairments are often dis-tressing for carers as well as patients. Such non-cognitive symptoms are often cited as a contributing reason for admis-sion into institutionalised care. The ability to interpret emotional cues is crucial to healthy psychological function and relationships and impaired emotional facility may lead to antisocial behavior. Understanding the origins of the non-cognitive aspects of AD may lead to an improvement in the management of sufferers and ease the carer burden. In a cross-sectional study we recorded patients’ facial processing abilities, (emotion and identity recognition) and disease severity (ADAS-cog, Neuropsychiatic Inventory) and investigated the regional cerebral blood flow correlates of facial emotion processing deficits using 99Tcm HMAPO rCBF SPECT. Using statistical parametric mapping (SPM) we iden-tified decreased blood flow in posterior frontal regions specifically associated with emotion perception deficits. Non-emotional facial processing abilities or disease severity. The posterior frontal lobe has been identified in previous stud-ies in the absence of dementia as being important in emotion processing. The results suggest that the cognitive disease severity, in combination with the facial processing ability, do not completely explain facial emotion processing in AD patients and that the posterior frontal lobe mediates such behaviour.

关键词： Alzheimer's Disease Emotion SPECT rCBF Facial Processing Dementia

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土地资源评价信息系统——以延安地区为例

水土保持学报 1989年第1期3卷 1-9页

作者：傅伯杰 donald A. Davidson 北京大学地理系英国Stirling大学环境科学系

土地资源信息系统是在计算机软硬件支撑下,将土地空间信息以一定格式输入、存贮、检索、显示和综合分析应用的技术系统。它是土地评价、土地规划和土地管理的强有力工具。本文以延安地区为例,运用网格数据格式,建立了土地资源评价信息系... 详细信息

土地资源信息系统是在计算机软硬件支撑下,将土地空间信息以一定格式输入、存贮、检索、显示和综合分析应用的技术系统。它是土地评价、土地规划和土地管理的强有力工具。本文以延安地区为例,运用网格数据格式,建立了土地资源评价信息系统,完成了农业、林业、牧业土地评价,为区域土地利用规划和合理利用土地提供了科学依据。

关键词：土地资源信息系统计算机制图系统要素图土地资源评价土地评价土地利用规划土地规划延安陕西

The Influence of Seasonal Changes and Headwaters on Physico-chemical Dynamics of Temengor Reservoir, Malaysia

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湿地科学 2011年第4期9卷 314-321页

作者： Zarul Hazrin Hashim Asmah Patiroi Mashhor Mansor Shahrul Anuar Md. Sah donald C. j.ckson School of Biological Sciences Universiti Sains Malaysia Department of Wildlife Fisheries and Aquaculture Mississippi State University

A study on physico-chemical dynamics of Temengor Reservoir was conducted to determine whether headwaters and seasonal changes play a maj.r role in regulating physico-chemical dynamics of Temengor Reservoir. Temengor Reservoir receives water from its surrounding water catchments and headwaters. Then, the water flows into a series of hydroelectric dams, namely the Bersia, Kenering and Chenderoh dams. Generally, water quality in Temengor Reservoir can be classified as Class I. Physico-chemical trends showed that water quality in euphotic zone of Temengor Reservoir is stable and consistent. Two-way ANOVA analyses showed that seasonal variations only affected water temperature, Secchi disc's depth and nitrate-nitrogen. Based on Tukey's post-hoc test, all three headwaters in this study exert no influence to the reservoir's water quality. These insignificant differences were probably due to water temperature and the size of the headwaters and the reservoir itself. In situ parameters profiling showed that the epilimnion zone in Temengor Reservoir is from the surface to 6 m depth, the metalimnion zone is from 6 m to 12 m depth and the hypolimnion zone is from 12 m depth onwards to the bottom of the reservoir. Thus, continuous water profiling monitoring that covers high and low water levels need to be conducted to determine characteristics of the physico-chemical dynamics in the water column and also to analyse changes in reservoir layers. Through these studies, discontinuity trends in the Perak River could be determined and suggestions to the respective agencies could be made to conserve and to sustain downstream biodiversity.

关键词：湿地物理化学季节变化研究分析