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Liquid encapsulation in a freezing sessile drop

第十二届全国流体力学学术会议

作者：曾昊吕思佳 dominique legendre 孙超清华大学能源与动力工程系燃烧能源中心图卢兹流体力学研究所图卢兹大学清华大学航空航天学院工程力学系

固体表面上的液滴凝固是在自然环境和工业生产中的一种常见现象。重力的存在使液滴的形状在不同表面场景下可能出现复杂的变化,这为我们预测液滴凝固形貌变化与动态特性带来了挑战。我们通过实验和理论模型研究了不同Bo数下的悬垂液滴... 详细信息

固体表面上的液滴凝固是在自然环境和工业生产中的一种常见现象。重力的存在使液滴的形状在不同表面场景下可能出现复杂的变化,这为我们预测液滴凝固形貌变化与动态特性带来了挑战。我们通过实验和理论模型研究了不同Bo数下的悬垂液滴与水平固着液滴的凝固特征。我们发现,不同方向的重力会影响液滴凝固前的形状如液滴高度、接触角等几何特征,受影响的程度主要与液滴Bo数有关。在液滴凝固过程中剩余液滴的形状依然受到重力影响,重力通过这种方式继续影响液滴凝固后的最终形状。对比不同重力方向下液滴凝固过程中固液界面演化曲线,我们发现由于重力导致的液滴高度差别,悬垂液滴明显具有更长的凝固时间,但在相同的时间范围内,悬垂液滴与水平固着液滴具有相似的固液界面演化规律。通过对液滴凝固过程中的重要参数进行无量纲化,我们发现不同重力方向下液滴凝固过程中的固液界面演化过程依然具有自相似性。不同Bo数下液滴凝固时间与液滴高度的关系基本满足平方标度率关系,说明在液滴凝固过程中竖直方向上的导热占据主导。理论模型预测结果与实验测量结果吻合良好。

关键词：多相流表面液滴凝固过程重力

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Droplet 2023年第4期2卷 120-126页

作者： Sijia Lyu Xun Zhu dominique legendre Chao Sun Center for Combustion Energy Key Laboratory for Thermal Science and Power Engineering of Ministry of EducationDepartment of Energy and Power EngineeringTsinghua UniversityBeijingChina Institut de Mécanique des Fluides de Toulouse(IMFT) Universitéde ToulouseCNRS‐ToulouseFrance Department of Engineering Mechanics School of Aerospace EngineeringTsinghua UniversityBeijingChina

During the solidification of a sessile drop,the effect of heat exchange from the gaseous environmental medium is generally ***,by combining experimental observations,direct numerical simulations,and a theoretical model,we have demonstrated that the environmental medium,particularly one with high thermal conductivity such as a liquid,has nonnegligible heat exchange with both the drop and the substrate,leading to accelerated cooling of the outer surface of the sessile ***,it causes alterations in the geometry of the freezing front and ultimately results in the formation of a solidified shell that encloses the ***,the encapsulated liquid continues to solidify,which induces volume change and consequently changes the final outcome of the freezing *** study highlights the importance of considering the properties of the environmental medium and provides novel strategies to manipulate the freezing rate and reshape the morphology of the solidified drop.

关键词： solidification freezing outer

Going straight for the gut:gut-brain axis pathology and treatment of Parkinson's disease

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Neural Regeneration Research 2024年第10期19卷 2111-2112页

作者： dominique Ebedes Cesar V.Borlongan University of South Florida Morsani College of Medicine TampaFLUSA Center of Excellence for Aging and Brain Repair Department of Neurosurgery and Brain RepairUniversity of South Florida Morsani College of MedicineTampaFLUSA

This perspective focuses on the recent literature regarding the role of the gut-brain axis(GBA) in fecal microbiota transplantation(FMT) and stem cell therapy(SCT) in Parkinson's disease(PD).PD is the second most common neurodegenerative disease in the United States,yet therapies remain *** research suggests that the GBA may play a role in the pathogenesis of *** FMT as well as SCT offer promising new avenues for PD *** bing the interactions between FMT and SCT with the GBA may reveal novel therapeutics for PD.

关键词： straight pathology pathogenesis

一种结合VoF与IBM的计算方法:可用于模拟液膜和液滴的结冰过程

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一种结合VoF与IBM的计算方法:可用于模拟液膜和液滴的结冰过程

Numerical study of convective heat transfer in static arrangements of particles with arbitrary shapes:A monolithic hybrid lattice Boltzmann-finite difference-phase field solver

第十一届全国流体力学学术会议

作者：吕思佳王珂张震桐 Anna?g Pedrono 孙超 dominique legendre 清华大学能源与动力工程系热科学与动力工程教育部重点实验室燃烧能源中心图卢兹大学图卢兹流体力学研究所

这项工作致力于开发一种新的结合VoF与IBM的计算方法,可用于模拟液膜和液滴的结冰问题。利用VoF和IBM方法与温度方程耦合,能够得到结冰界面的位置和形状随时间的演化,并且在该模拟中考虑了由于水与冰之间的密度差造成的体积膨胀,且考虑... 详细信息

这项工作致力于开发一种新的结合VoF与IBM的计算方法,可用于模拟液膜和液滴的结冰问题。利用VoF和IBM方法与温度方程耦合,能够得到结冰界面的位置和形状随时间的演化,并且在该模拟中考虑了由于水与冰之间的密度差造成的体积膨胀,且考虑了由于表面张力和重力平衡引起的实时的液体部分的变形问题。理论解与实验结果均证实了此计算方法的有效性和准确性。我们研究了Stefan数、固液密度比等因素对液膜和液滴结冰界面演化的影响。针对液滴结冰,我们还研究了液滴与冷却板之间的接触角、液滴所受重力和表面张力对结冰过程的影响。该模拟方法能很好地展现液滴内部的温度场,结冰界面的实时形状,凝固时间。并且由于计算的毫米级液滴的Weber数和Capillary数均很小,CSF-VoF杂散电流被证实不会影响液滴的结冰过程。且模拟结果表明液滴的形状,尤其是完全凝结时冰滴顶部的尖角以及结冰界面与液滴轮廓的实时夹角都与实验结果相符。了解液膜和液滴的结冰过程及其控制参数,可以很好地调控生产和生活中的液体结冰问题。

关键词：结冰液膜液滴结合VoF与IBM计算方法

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Particuology 2024年第2期85卷 186-197页

作者： Reza Namdar Mohammadhassan Khodsiani Hesameddin Safari Tanya Neeraj Seyed Ali Hosseini Frank Beyrau Benoit Fond dominique Thevenin Fathollah Varnik Interdisciplinary Centre for Advanced Materials Simulation(ICAMS) Ruhr-University BochumBochum44801Germany Laboratory of Technical Thermodynamics University of Magdeburg"Otto von Guericke"Magdeburg39106Germany Laboratory of Fluid Dynamics and Technical Flows University of Magdeburg"Otto von Guericke"MagdeburgD-39106Germany Department of Mechanical and Process Engineering ETH ZurichZurich8092Switzerland ONERA The French Aerospace Lab Department of AerodynamicsAeroelasticity and Acoustics(DAAA)Paris-Saclay UniversityMeudon92190France

A compressible lattice Boltzmann-finite difference method is extended by the phase-field approach into a monolithic scheme to study fluid flow and heat transfer through regular arrangements of solid bodies of circular,elliptical and irregular *** advantage of using the phase-field method is demon-strated both in its simplicity of accounting for flow and thermal boundary conditions at solid surfaces with irregular shapes and in the capability of generating such complex-shaped *** an array of discs,numerical results for the overall solid-to-gas heat transfer rate are validated via experiments on flow through arrays of hot *** thus validated compressible LB-FD-PF hybrid scheme is used to study the dependence of heat transfer on flow and thermal boundary conditions(Reynolds number,temperature difference between the hot solid bodies and the inlet gas),porosity as well as on the shape of solid *** are rationalized in terms of the residence time of the gas close to the solid body and downstream variations of gas velocity and *** for further applications of the proposed methodology are also discussed.

关键词： Lattice Boltzmann method Finite difference scheme Convective heat transfer Diffuse interface Thermal compressible flow

Health Systems Strengthening to Tackle the Global Burden of Pediatric and Congenital Heart Disease: A Diagonal Approach

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Congenital Heart Disease 2024年第2期19卷 131-138页

作者： dominique Vervoort Amy Verstappen Sreehari Madhavankutty Nair Chong Chin Eu Bistra Zheleva Institute of Health Policy Management and EvaluationUniversity of TorontoTorontoCanada Division of Cardiac Surgery University of TorontoTorontoCanada Global Alliance for Rheumatic and Congenital Hearts PhiladelphiaUSA Department of Health Services Government of KeralaKeralaIndia Ministry of Health PutrajayaMalaysia Children’s HeartLink MinneapolisUSA

1 Background Congenital heart disease(CHD)is the most common major congenital anomaly,affecting approximately one in every 100 live births[1].Among congenital anomalies,66%of preventable deaths are due to CHD,and 58%of the avertable morbidity and mortality due to congenital anomalies would result from scaling congenital heart surgery services[2].Every year,nearly 300,000 children and adults die from CHD,the majority of whom live in low-and middle-income countries(LMICs)[3].Approximately 49%of all individuals with CHD will require surgical or interventional care at some point in their lifetime[4];as a result of advances in access to and the delivery of such services,over 95%of children born with CHD in high-income countries now live into adulthood[3].Here,adults have surpassed children in the number of CHD cases at a ratio of 2:1[5].

关键词： Congenital heart disease pediatric heart disease global health health systems health policy

Protein-S-100-beta is increased in patients with decompensated cirrhosis admitted to ICU

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Journal of Intensive Medicine 2024年第2期4卷 222-230页

作者： Nicolas Weiss Simona Tripon Maxime Mallet Françoise Imbert-Bismut Mehdi Sakka dominique Bonnefont-Rousselot Philippe Sultanik Sarah Mouri Marika Rudler dominique Thabut Sorbonne Université AP-HP.Sorbonne UniversitéHôpital de la Pitié-SalpêtrièreDépartement de NeurologieUnitéde Médecine Intensive RéanimationàOrientation NeurologiqueParisFrance Brain Liver Pitié-Salpêtrière(BLIPS)Study Group INSERM UMR_S 938Centre de recherche Saint-AntoineMaladies métaboliquesBiliaires et Fibro-Inflammatoire du FoieInstitute of Cardiometabolism and Nutrition(ICAN)ParisFrance Groupe de Recherche Clinique en REanimation et Soins intensifs du Patient en Insuffisance Respiratoire aiguE(GRC-RESPIRE)Sorbonne Université ParisFrance Assistance Publique-Hôpitaux de Paris AP-HP.Sorbonne UniversitéHôpital de la Pitié-SalpêtrièreService d'hépato-GastroentérologieUnitéde Soins Intensifs d'HépatologieParisFrance Assistance Publique-Hôpitaux de Paris AP-HP.Sorbonne UniversitéService de Biochimie MétaboliqueHôpitaux Universitaires Pitié-Salpêtrière-Charles FoixDMU BioGeMParis F-75013France UniversitéParis Cité UFR de PharmacieCNRSInsermUTCBSParisFrance

Background Hepatic encephalopathy(HE)is highly prevalent in patients with liver *** pathophysiology of HE is centered on the synergic role of hyperammonemia and systemic ***,some data suggest altered functioning of the blood–brain barrier(BBB).Assessing BBB function is challenging in clinical practice and at the ***-S-100 Beta(PS100-Beta)could be a useful peripheral marker of BBB permeability in *** study aimed to assess plasmatic PS100-Beta levels in a prospective cohort of patients admitted to the intensive care unit(ICU)with decompensated cirrhosis with and without overt *** We retrospectively evaluated a prospective cohort of cirrhotic patients admitted to the ICU from October 2013 to September 2015 that had an available plasmatic PS100-Beta *** with previous neurological impairment or limitation of intensive or resuscitative measures were *** HE was defined as West-Haven grades 2 to *** patients were compared to a control cohort of outpatient clinic cirrhotic and non-cirrhotic patients explored for isolated elevation of liver *** ICU discharge,the patients were followed for at least 3 months for the occurrence of overt *** outcomes(liver transplantation or death)were *** ability of PS100-Beta–in combination with other factors–to predict overt HE was evaluated in a multivariate analysis using logistic *** ratios were used to determine the effects and calculate odds ratios(OR).Survival analysis was performed by using the Kaplan–Meier method and survival between groups was compared using a Log-rank *** A total of 194 ICU patients and 207 outpatients were included in the *** levels of plasmatic PS100-Beta were detected in the ICU decompensated cirrhotic patients compared with the outpatients([0.15±0.01]mg/L vs.[0.08±0]mg/L,P<0.001).ICU patients with overt HE had higher levels of PS100-Beta([0.19±0.03]mg/L)compared with the

关键词： Cirrhosis Hepatic encephalopathy Blood-brain barrier PS100-Beta Liver disease

The Impact of the Inclusion of MgO Nano-Fillers in a Polyethylene Matrix on Dielectric Strength and Resistance to Partial Discharges

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Open Journal of Applied Sciences 2024年第3期14卷 626-634页

作者： Virginie Griseri dominique Mary David Malec Eric David Laboratoire Plasma et Conversion d’énergie Université de Toulouse CNRS UPS INPT Route de Narbonne Toulouse France É cole de Technologie Supérieure de Montréal Rue Notre-Dame Ouest Montréal Canada

One commonly used strategy to enhance polymers specific properties such as the resistance to partial discharges erosion is the incorporation into the polymeric matrix of inorganic micro or nanoparticles. This study focused on the dielectric properties of Low-Density Polyethylene (LDPE) filled with nano-sized Magnesium Oxide (MgO) particles compounded by thermo-mechanical process and one of the purposes was to establish appropriate processing parameters in order to reach the desired dielectric properties. LDPE was used as a matrix and was reinforced by MgO particles having a nominal average size of 30 nm. The MgO nanoparticles were treated with a silane coupling agent (3-Glycidyloxypropyl Trimethoxysilane). The samples were initially prepared in a melt-mixing chamber with a MgO content of 1% wt. These pre-mixed samples were further treated by the means of thermo-mechanical mixing in a conical co-rotating twin-screw extruder in order to improve the dispersion and distribution of the MgO particles. In this report, both lifetime under a PD activity and AC dielectric strength of pure and nano-filled LDPE samples have been measured and compared. Nano-filled LDPE samples were found to exhibit an improve lifetime, without any detrimental impact on their short-term dielectric strength. This suggests that nano-filled LDPE may be for electric applications for which the dielectric materials may be exposed to partial discharge activities. This is significant result for the use of MgO-reinforced PE as an insulating material for HV cables since the resistance to PD is closely related to treeing resistance which is the main electrical degradation mechanism that leads to failure for shielded extruded power cables.

关键词： Low Density Polyethylene MgO Nanofillers Dielectric Strength Partial Discharges Resistance

Finding biomarkers of experience in animals

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Journal of Animal Science and Biotechnology 2024年第3期15卷 925-944页

作者： Sarah Babington Alan J.Tilbrook Shane K.Maloney Jill N.Fernandes Tamsyn M.Crowley Luoyang Ding Archa H.Fox Song Zhang Elise A.Kho Daniel Cozzolino Timothy J.Mahony dominique Blache School of Agriculture and Environment The University of Western AustraliaCrawleyWA 6009Australia Centre for Animal Science The Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandSt LuciaQLD 4072Australia School of Veterinary Science The University of QueenslandGattonQLD 4343Australia School of Human Sciences The University of Western AustraliaCrawleyWA 6009Australia School of Medicine Deakin UniversityGeelongVIC 3217Australia Poultry Hub Australia University of New EnglandArmidaleNSW 2350Australia College of Animal Science and Technology Yangzhou UniversityYangzhou 225009China Centre for Nutrition and Food Sciences The Queensland Alliance for Agriculture and Food InnovationThe University of QueenslandSt LuciaQLD 4072Australia

At a time when there is a growing public interest in animal welfare,it is critical to have objective means to assess the way that an animal experiences a *** is critical to ensure appropriate animal welfare *** behavioural,physiological,and neurobiological indicators that are used to assess animal welfare can verify the absence of extremely negative *** welfare is more than an absence of negative outcomes and an appropriate indicator should reflect the full spectrum of experience of an animal,from negative to *** this review,we draw from the knowledge of human biomedical science to propose a list of candidate biological markers(biomarkers)that should reflect the experiential state of non-human *** proposed biomarkers can be classified on their main function as endocrine,oxidative stress,non-coding molecular,and thermobiological *** also discuss practical challenges that must be addressed before any of these biomarkers can become useful to assess the experience of an animal in real-life.

关键词： Animal experience Animal welfare Biomarker Stress Welfare assessment