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New approaches to diagnostics and treatment of cholangiocellular cancer based on photonics methods

Frontiers of Optoelectronics 2020年第4期13卷 352-359页

作者： dmitry V.yakovlev Dina S.FARRAKHOVA Artem A.SHIRYAEV Kanamat T.EFENDIEV Maxim V.LOSCHENOV Liana M.AMIRKHANOVA dmitry O.KORNEV Vladimir V.LEVKIN Igor V.RESHETOV Victor B.LOSCHENOV Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of SciencesMoscow 117997Russia Prokhorov General Physics Institute of Russian Academy of Sciences Moscow 119991Russia University Clinical Hospital No.1 Oncology CenterI.M.Sechenov First Moscow State Medical University(Sechenov University)Ministry of Health of the Russian FederationMoscow 119991Russia Department of Laser Micro- Nano-and BiotechnologyInstitute of Engineering Physics for BiomedicineNational Research Nuclear University MEPhIMoscow 115409Russia

Cholangiocellular cancer(CCC)is an oncological disease of the bile ducts characterized by a high mortality *** date,the use of standard methods for the diagnosis and treatment of CCC has not been able to reduce mortality from this *** work presents the results of fluorescence diagnostics(FD),which consists in using a modified optical fiber and photodynamic therapy(PDT)using a therapeutic laser instead of a low-intensity *** technique was tested on 43 patients in a clinical *** results obtained indicate a direct correlation between spectroscopic and video FD ***,a direct correlation was found between the photobleaching of a chlorin e6-based photosensitizer,with the commercial names of PhotoIon Radachlorin and Photoran and stricture *** findings demonstrate the possibility of using a therapeutic laser with a wavelength of 660 nm for both diagnosis and treatment of bile ducts cancer,which results in a significant reduction of the operation time without decreasing its effectiveness.

关键词： cholangiocellular cancer(CCC) fluorescent diagnostics(FD) photodynamic therapy(PDT) chlorin e6 PhotoIon spectroscopic method video fluorescent method photobleaching cancer bile ducts tumor intraoperation diagnostics photosensitizer(PS)

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Repeated kimberlite magmatism beneath Yakutia and its relationship to Siberian flood volcanism:Insights from in situ U–Pb and Sr–Nd perovskite isotope analysis

Repeated kimberlite magmatism beneath Yakutia and its relati...

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中国科学院地质与地球物理研究所2014年度（第14届）学术年会

作者： Jing Sun Chuan-Zhou Liu Sebastian Tappe Sergey I.Kostrovitsky Fu-Yuan Wu dmitry yakovlev Yue-Heng Yang Jin-Hui Yang State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of Sciences University of Chinese Academy of Sciences De Beers Group Exploration School of Geosciences University of the Witwatersrand Institute of Geochemistry Siberian Branch of the Russian Academy of Sciences

We report combined U–Pb ages and Sr–Nd isotope compositions of perovskites from 50 kimberlite occurrences,sampled from 9 fields across the Yakutian kimberlite province on the Siberian *** new U–Pb ages,together with previously reported geochronological constraints,suggest that kimberlite magmas formed repeatedly during at least 4 episodes:Late Silurian–Early Devonian(419–410 Ma),Late Devonian–Early Carboniferous(376–347 Ma),Late Triassic(231–215 Ma),and Middle/Late Jurassic(171–156 Ma).Recurrent kimberlite melt production beneath the Siberian craton–before and after flood basalt volcanism at 250 Ma–provides a unique opportunity to test existing models for the origin of global kimberlite *** internally consistent Sr and Nd isotope dataset for perovskites reveals that the Paleozoic and Mesozoic kimberlites of Yakutia have distinctly different initial radiogenic isotope *** exists a notable increase in the initial 143Nd/144Nd ratios through time,with an apparent isotopic evolution that is intermediate between that of Bulk Earth and Depleted MORB *** the Paleozoic samples range between initial 87Sr/86Sr of 0.7028–0.7034 and 143Nd/144Nd of 0.51229–0.51241,the Mesozoic samples show values between 0.7032–0.7038 and 0.51245–0.51271,***,perovskites from all studied Yakutian kimberlite fields and age groups have moderately depleted initialεNd values that fall within a relatively narrow range between+1.8 and+*** perovskite isotope systematics of the Yakutian kimberlites are interpreted to reflect magma derivation from the convecting upper mantle,which appears to have a record of continuous melt depletion and crustal recycling throughout the *** analyzed perovskites neither record highly depleted nor highly enriched isotopic components,which had been previously identified in likely plume-related Siberian Trap *** Siberian craton has frequently been suggested to represent a type example of an a

关键词： perovskite recurrent kimberlite magmatism Siberian craton large igneous provinces(LIPs) SIMS

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液晶显示器的优化与模型试验

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现代显示 2004年第5期 43-45页

作者： Vladimir Chigrinov dmitry yakovlev 郭海成公伟刚宋行宾周立祁技超香港科技大学电子与电子工程系京东方光电科技有限公司

利用专门软件对LCD进行模型试验和优化是一项普遍采用的技术,并且是开发现代LCD结构和了解其工作机理的强有力工具。

关键词： LCD 液晶显示器工作机理软件优化工具开发发现

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Alternative Strategy for Development of Dielectric Calcium Copper Titanate‑Based Electrolytes for Low‑Temperature Solid Oxide Fuel Cells

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Nano-Micro Letters 2025年第1期17卷 310-332页

作者： Sajid Rauf Muhammad Bilal Hanif Zuhra Tayyab Matej Veis MAKYousaf Shah Naveed Mushtaq dmitry Medvedev Yibin Tian Chen Xia Martin Motola Bin Zhu College of Mechatronics and Control Engineering Shenzhen UniversityShenzhen 518060People’s Republic of China Department of Inorganic Chemistry Faculty of Natural SciencesComenius University BratislavaIlkovicova684215 BratislavaSlovakia Energy Storage Joint Research Center School of Energy and EnvironmentSoutheast UniversityNanjing 210096People’s Republic of China Hydrogen Energy Laboratory Ural Federal University620002 EkaterinburgRussia Laboratory of Electrochemical Devices Based on Solid Oxide Proton Electrolytes Institute of High Temperature Electrochemistry620066 EkaterinburgRussia School of Microelectronics Hubei UniversityWuhan 430062People’s Republic of China

The development of low-temperature solid oxide fuel cells(LT-SOFCs)is of significant importance for realizing the widespread application of *** has stimulated a substantial materials research effort in developing high oxide-ion conductivity in the electrolyte layer of *** this context,for the first time,a dielectric material,CaCu_(3)Ti_(4)O_(12)(CCTO)is designed for LT-SOFCs electrolyte application in this *** individual CCTO and its heterostructure materials with a p-type Ni_(0.8)Co_(0.15)Al_(0.05)LiO_(2−δ)(NCAL)semiconductor are evaluated as alternative electrolytes in LT-SOFC at 450–550℃.The single cell with the individual CCTO electrolyte exhibits a power output of approximately 263 mW cm^(-2) and an open-circuit voltage(OCV)of 0.95 V at 550℃,while the cell with the CCTO–NCAL heterostructure electrolyte capably delivers an improved power output of approximately 605 mW cm^(-2) along with a higher OCV over 1.0 V,which indicates the introduction of high hole-conducting NCAL into the CCTO could enhance the cell performance rather than inducing any potential short-circuiting *** is found that these promising outcomes are due to the interplay of the dielectric material,its structure,and overall properties that led to improve electrochemical mechanism in CCTO–***,density functional theory calculations provide the detailed information about the electronic and structural properties of the CCTO and NCAL and their heterostructure CCTO–*** study thus provides a new approach for developing new advanced electrolytes for LT-SOFCs.

关键词： LT-SOFCs Dielectric CaCu_(3)Ti_(4)O_(12) Semiconductor Ni_(0.8)Co_(0.15)Al_(0.05)LiO_(2−δ) Ionic conductivity Heterostructure electrolyte

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Choosing configurations of transmission line tower grounding by back flashover probability value

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Frontiers in Energy 2016年第2期10卷 213-226页

作者： dmitry KUKLIN Centre for Physical and Technological Problems of Energy in NorthemAreas Apatity 184209 Russia

There is a considerable number of works devoted to electrical characteristics of grounding. These characteristics are important in general. However, in application to grounding of transmission line towers they are not enough to determine what grounding construction is preferable in some particular case, because these characteristics are calculated or measured apart from the grounded object, and only limited number of current （or voltage） source waveforms is used. This paper indicates reasons in favor of the fact that to choose the optimum design of grounding, the calculation model should include the tower as it is. The probability of back flashover, which provides both qualitative and quantitative estimate of the grounding structure efficiency, can be taken as the criterion for the grounding design. The insulation flashover probability is calculated on the basis of engineering method, which evaluates breakdown strength of insulation for nonstandard waveshapes, and probability data on lightning currents. Different approaches are examined for identifying the back flashover probability, as not only amplitudes but also other parameters can be taken into account. Finite-difference time-domain method is used for calculations of transients. It is found that lightning current waveform can greatly influence calculated back flashover probability value.

关键词： grounding transmission line tower back flashover probability FDTD method

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Real-time decay of fluorinated fullerene molecules on Cu（001） surface controlled by initial coverage

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Nano Research 2018年第4期11卷 2069-2082页

作者： Andrey I. Oreshkin dmitry A. Muzychenko Sergey I. Oreshkin Vladimir A. yakovlev Palanichamy Murugan S. Selva Chandrasekaran Vijay Kumar Rauf Z. Bakhtizin Department of Physics Lomonosov Moscow State University 119991 Moscow Russia Sternberg Astronomical Institute Lomonosov Moscow State University 119234 Moscow Russia Institute of Petrochemical Synthesis Russian Academy of Sciences 119991 Moscow Russia CSIR Central Electrochemical Research Institute Karaikudi 630003 Tamil Nadu India Dr. Vijay Kumar Foundation 1969 Sector 4 Gurgaon 122001 Haryana India Center for Informatics School of Natural Sciences Shiv Nadar University NH91 Tehsil Dadari Gautam Budh Nagar 201314 Uttar Pradesh India Department of Physical Electronics Bashkir State University 450074 Ufa Russia

In this study, the evolution of C60F18 molecules on a Cu（001） surface was studied by means of scanning tunneling microscopy and density functional theory calculations. The results showed that fluorinated fuUerenes （tortoise-shaped polar C60F18） decay on Cu（001） surfaces by a step-by-step detachment of F atoms from the C60 cage. The most favorable adsorption configuration was realized when the F atoms of C60F18 pointed towards the Cu surface and six F atoms were detached from it. The results also showed that a further decay of C60F12 molecules strongly depended on the initial C60F18 coverage. The detached F atoms initially formed a two-dimensional （2D） gas phase which then slowly transformed into F-induced surface structures. The degree of contact between the C60F12 molecules and the Cu（001） surface depended on the density of the 2D gas phase. Hence, the life-time of fluorinated fullerenes was determined by the density of the 2D gas phase, which was affected by the formation of new F-induced structures and the decay of C60F12 molecules.

关键词： fluorinated fullerene (001) Cu surface two-dimensional (2D)molecular island 2D gas phase self-assembling molecules scanning tunneling microscopy (STM) density functional theory(DFT)

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E-beam generation in discharges initiated by voltage pulses with a rise time of 200 ns at an air pressure of 12.5-100 kPa

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Plasma Science and Technology 2019年第4期21卷 52-60页

作者： Victor TARASENKO dmitry BELOPLOTOV Mikhail LOMAEV dmitry SOROKIN Institute of High Current Electronics Siberian Bran ch.Russian Academy of Sciences.Tomsk&34055.Russia National Research Tomsk State University.Tomsk 634050 Russia

The effect of air pressure(12.5,25,50,and 100 kPa)on the gen eration of runaway electron beams in a non-uniform electric field when applying voltage pulses(~35 kV)with a rise time of?200 ns has been *** results show that the discharge has various stages:streamer,diffuse,and ***,a wide streamer develops in the gap and a diffuse discharge is formed.A spark is formed u 100 ns after the *** current pulse of a supershort avalanche electron beam(SAEB)was measured with a collector at various pressures of *** show that there are two modes of generation of run away *** an air pressure of 25-100 kPa,a single SAEB current pulse with a full width at half-maximum(FWHM)of 120-140 ps is *** the air pressure of 12.5 kPa,two current pulses of the electron beam are *** of the first and second current pulses are ul40ps and u300 ps,*** current pulse amplitude of the second electron beam is higher than that of the first one,but the electron energy is less.

关键词： diffuse discharge runaway electrons streamer breakdown displacement current

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Adhesion at friction and wear

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Friction 2022年第11期10卷 1859-1878页

作者： dmitry P.MARKOV Research Institute of Railway Transport Moscow 129851Russia

Our understanding of the surrounding world,from friction to the origin of life,depends on how we imagine the contact interaction of condensed *** are the forces acting in contact with solids?Do they attract(adhesive)or repel(dehesive)?Theory and research at the atomic–molecular level have shown that the force are adhesive,but everyday experiences cast doubt on this *** article addresses this issue by considering the mistakes made in experimental and theoretical tribology and surface *** into account the theories of hybridization and dehybridization of electron orbitals and valence bonds,the views on the structure of the surfaces of condensed bodies and the force arising during contact interaction are *** influence of van der Waals,hydrogen,covalent,metallic,and ionic bonds on the properties of lubricants is *** contours of the dehesive–deformation theory of friction and wear are also outlined.

关键词： atomic and molecular interactions adhesion cohesion dehesion friction wear

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Positive and negative streamers in air and nitrogen in a sharply inhomogeneous electric field under conditions of runaway electron generation

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High Voltage 2023年第3期8卷 527-537页

作者： dmitry Beloplotov Victor Tarasenko dmitry Sorokin Cheng Zhang Tao Shao Institute of High Current Electronics Siberian Branch of the Russian Academy of ScienceTomskRussia Beijing International S&T Cooperation Base for Plasma Science and Energy Conversion Institute of Electrical EngineeringChinese Academy of SciencesBeijingChina

The development of positive and negative streamers in a point-to-plane gap filled with air and nitrogen at various pressures(50-200 kPa)and voltages(8-25 kV)was studied.A four-channel intensified charge-coupled device(ICCD)and a streak-camera were *** parameters were measured with high resolution(10 GHz).An original method of measuring a displacement current caused by a streamer was *** was expected,positive streamer branches in nitrogen at low voltages and/or elevated pressures while a large-diameter streamer is formed in ***,at high voltages or negative polarity,the large-diameter streamer is formed both in nitrogen and air in the entire pressure *** was found that runaway electrons(REs)are generated in the very first picoseconds of gas ionisation near the pointed *** was assumed that REs can be generated near the pointed anode and produce bremsstrahlung radiation due to a sharply inhomogeneous distribution of electrical *** was found that in the final stage of negative streamer development in air and nitrogen,the gas between the streamer front and the opposite electrode is ionised almost simultaneously in the entire volume when the streamer diameter is almost equal to the interelectrode gap.

关键词： sharply inhomogeneous electrode

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Formation of diffuse and spark discharges between two needle electrodes with the scattering of particles

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Plasma Science and Technology 2024年第9期26卷 32-39页

作者： Victor F TARASENKO dmitry V BELOPLOTOV Alexei N PANCHENKO dmitry A SOROKIN Institute of High Current Electronics Siberian BranchRussian Academy of SciencesTomsk 634055Russia National Research Tomsk State University Tomsk 634050Russia

The development of a nanosecond discharge in a pin-to-pin gap filled with air at atmospheric pressure has been studied with high temporal and spatial resolutions from a breakdown start to the spark *** and negative nanosecond voltage pulses with an amplitude of tens of kilovolts were ***-resolved images of the discharge development were taken with a fourchannel Intensified Charge Coupled Device(ICCD)*** minimum delay between the camera channels could be as short as≈0.1 *** made it possible to study the gap breakdown process with subnanosecond *** was observed that a wide-diameter streamer develops from the high-voltage pointed *** ionization processes near the grounded pin electrode started when the streamer crossed half of the *** bridging the gap by the streamer,a diffuse discharge was *** development of spark leaders from bright spots on the surface of the pointed electrodes was observed at the next *** was found that the rate of development of the spark leader is an order of magnitude lower than that of the wide-diameter *** thin luminous tracks were observed against the background of a discharge plasma *** has been established that the tracks are adjacent to brightly glowing spots on the electrodes and are associated with the flight of small particles.

关键词： needle electrodes short voltage pulses atmospheric air streamer breakdown diffuse and spark discharges scattering metal particles

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