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Protective effects of prostaglandin E1 on hepatocytes

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World Journal of Gastroenterology 2000年第3期6卷 326-329页

作者： Liu XL Fan dm Fourth Mil Med Univ Xijing Hosp Inst Digest Dis Xian 710032 Peoples R China

INTRODUCTION E Numerous studies have demonstrated the protective action of prostaglandin E1(PGE1) on experimental animal models of liver injury and on patients with

关键词： prostaglandin El hepatitis liver injury hepatic cytoprotective effects lipid microspheres

Modified Dye for Water-Fast Ink-Jet Printing

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Journal of Donghua University(English Edition) 2001年第4期18卷 49-53页

作者：郑庆康朱谱新吴大诚 Lewis dm Textile College Sichuan University Chengdu 610065 China Depanment of Color Chemistry The University of Leeds LS2 9 JT UK

A quaternary ammonium compound containing amino acid residue was synthesized by Converting 3-chloro-2-hydroxy- propyalkyldimethylammonium chlorides into its epoxide derivatives, then attaching an amino acid to the epoxide derivatives synthesized a quaternary ammonium compound containing amino acid residue. Modified dyes were prepared by the ionotropy of anionic dyes with the quaternary ammonium compound containing amino acid residue. It was discovered that the modified dyes exhibited an excellent pH controllable solubility. These modified dyes have good water solubility at pH> 8.0, but they were water insoluble at pH < 6.5. On the printing paper, modified dyes in water-based ink-jet print ink could convert to water insoluble form and give prints excellent water fastness.

关键词： Modification, Dye, Printing

A case of cerebral malaria and dengue concurrent infection

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Asian Pacific Journal of Tropical Biomedicine 2013年第5期3卷 416-417页

作者： Anwar Alam Md dm Department of Neurology Ruban Emergency Hospital

Cerebral malaria and dengue are the common infections which cause higher mortality and morbidities in every part of the world especially in *** infection of cerebral malaria and dengue is rare entity due to different habitat of vectors and it was reported rarely from Southeast *** this case report,the authors reported a case of concurrent cerebral malaria and dengue which was recovered after eight days of admission with increase in morbidity.

关键词： Cerebral malaria Dengue Concurrent infection

CAdm1、E-cad在肝细胞肝癌组织中的表达及临床意义

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中国普通外科杂志 2015年第7期24卷 1046-1049页

作者：隋东明辽宁省盘锦市中医院普通外科辽宁盘锦124000

目的:探讨原发性肝细胞肝癌(HCC)组织中细胞黏附分子1(CAdm1)、上皮型黏附素(E-cad)的表达及临床意义。方法:采用免疫组化法检测84例HCC患者癌组织和癌旁组织中CAdm1、E-cad的表达情况,并对CAdm1、E-cad表达水平与患者临床病理特征的关... 详细信息

目的:探讨原发性肝细胞肝癌(HCC)组织中细胞黏附分子1(CAdm1)、上皮型黏附素(E-cad)的表达及临床意义。方法:采用免疫组化法检测84例HCC患者癌组织和癌旁组织中CAdm1、E-cad的表达情况,并对CAdm1、E-cad表达水平与患者临床病理特征的关系以及CAdm1、E-cad两者表达的关系进行分析。结果:CAdm1与E-cad在HCC组织中表达阳性率明显低于癌旁组织(Pdm1、E-cad表达与HCC患者的临床分期进展及肿瘤包膜完整性有关(P0.05);CAdm1与E-cad在HCC组织中的表达呈明显正相关(r=0.405,Pdm1、E-cad在HCC组织中呈低表达,且可能与HCC的发生发展、侵袭、转移密切相关,可作为预后指标。

关键词：癌,肝细胞细胞黏附分子肿瘤侵润

Solid state reaction of aromatic ketones with heteroaromatics

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Chinese Journal of Chemistry 1995年第6期13卷 520-524页

作者： Du, dm Meng, SM Wang, YM Meng, JB Zhou, XZ NANKAI UNIV DEPT CHEMTIANJIN 300071PEOPLES R CHINA YANBEI TEACHERS COLL DATONG 037000JILINPEOPLES R CHINA

The solid state reactions of p-nitroacetophenone, acetyl-ferrocene with indole were catalyzed by anhydrous zinc chloride or aluminum chloride, and gave exclusively the 1:2 condensation products. The solid state condensation of aromatic ketones with 1-phenyl-3-methyl-5-pyrazolone was also investigated, and the 1:1 and 2:1 condensation products were obtained. The structures of eleven new products were determined by IR, MS, H-1 NMR and elemental analysis.

关键词： solid state reaction aromatic ketone indole 1-phenyl-3-methyl-5-pyrazolone

Pharmacological effects of aqueous-ethanolic extract of Hibiscus rosasinensis on volume and acidity of stimulated gastric secretion

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Asian Pacific Journal of Tropical Medicine 2011年第11期4卷 883-888页

作者： Rajesh J Mandade SA Sreenivas dm Sakarkar Avijit Choudhury Pharmacology Department S.N.Institute of PharmacyPusadIndia Guru Nanak Institute of Pharmacy IbrahimpattnamHyderabad.(A.P.) India S.N.Institute of Pharmacy PusadIndia Pharmacology Department Shree Dhanvantary college pharmacyKimIndia

Objective:To explore the effects of extract of Hibiscus rosasinensis(***) on the volume,free and total acidity of gastric secretion induced by ***:Animals were kept on fasting for 48 *** the pylorus of each animal was *** were randomly divided into 5 groups and treated by carbachol at 600μg/*** animals in groupⅡ-Ⅴwere treated by *** extract at 250 and 500 mg/kg body weight,cimetidine at 2.5 mg/ kg and verapamil at 10 mg/kg body weight intraperitoneally,*** volume,free and total acidity of gastric secretion were observed and ***:It was found that the extract significantly reduced the volume,free and total acidity of gastric secretion(P<0.01). These reductions were comparable to cimetidine and *** the reduction in the volume and free acidity were more significant in cimetidine and verapamil treated group indicating that cimetidine and verapamil were more ***:The extract of *** can reduced the volume,free and total acidity of gastric secretion,and can be used effectively in the treatment of peptic ulcer.

关键词： Verapamil Cimetidine Carbachol Hibiscus rosasinensis Rats

Suppression of P-gp induced multiple drug resistance in a drug resistant gastric cancer cell line by overexpression of Fas

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World Journal of Gastroenterology 2000年第5期6卷 664-670页

作者： Yin F Shi YQ Zhao WP Xiao B Miao JY Fan dm Fourth Mil Med Univ Xinjing Hosp Inst Gastroenterol Dept Gastroenterol Xian 710033 Shaanxi Provinc Peoples R China

AIM To observe the drug sensitizing effect andrelated mechanisms of fas gene transduction onhuman drug-resistant gastric cancer cellSGC7901/VCR(resistant to Vincristine).METHODS The cell cycle alteration wasobserved by *** sensitivity of gastriccancer cells to apoptosis was determined by invitro apoptosis *** drug sensitization ofcells to several anti-tumor drugs was observedby MTT *** method wasused to show expression of P-gp and Topo Ⅱ ingastric cancer *** Comparing to SGC7901 and pBK-SGC7901/VCR,fas-SGC7901/VCR showeddecreasing G2 cells and increasing S cells,theG2 phase fraction of pBK-SGC7901/VCR wasabout 3.0 times that of fas-SGC7901/VCR,but Sphase fraction of fas-SGC7901/VCR was about1.9 times that of pBK-SGC7901/VCR,indicatingS phase arrest of fas-SGC7901/*** alsosuggested apoptosis of fas-SGC7901/VCR,fas-SGC7901/VCR was more sensitive to apoptosisinducing agent VM-26 than pBK-SGC7901/*** assay showed increased sensitization offas-SGC7901/VCR to DDP,MMC and 5-FU,butsame sensitization to VCR according to pBK-SGC7901/***7901,pBK-SGC7901/ VCRand fas-SGC7901/VCR had positively stainedTopo Ⅱ equally.P-gp staining in pBK- SGC7901/VCR was stronger than in SG07901,but there was little staining of P-gp in ***7901/*** fas gene transduction couldreverse the MDR of human drug-resistant gastriccancer cell SGC7901/VCR to a degree,possiblybecause of higher sensitization to apoptosis anddecreased expression of P-gp.

关键词： fas gene stomach neoplasms apoptosis drug resistance multiple antineoplastic agents immunocytochemistry/methods gene transduction

The Crystal structure of Hexakisammonium Diacety loctamoly bdate Tetrahydrate

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Chinese Journal of Structural Chemistry 2000年第3期19卷 191-194页

作者： Wang, S Lin, X Lu, CZ Wu, dm Yang, WB Zhuang, HH Chinese Acad Sci Fujian Inst Res Struct Matter State Key Lab Struct Chem Fuzhou 350002 Peoples R China

The title compound, 〔NH 4〕 6〔(CH 3CO) 2(Mo 8O 28 )〕·4H 2O, was produced from (NH 4) 6〔Mo 7O 24 〕·4H 2O aqueous solution in the presence of N 2H 4·H 2SO 4 and its structure has been deter... 详细信息

The title compound, 〔NH 4〕 6〔(CH 3CO) 2(Mo 8O 28 )〕·4H 2O, was produced from (NH 4) 6〔Mo 7O 24 〕·4H 2O aqueous solution in the presence of N 2H 4·H 2SO 4 and its structure has been determined by X ray single crystal analysis. The crystallographic data: C 4H 38 Mo 8N 6O 34 , M r =1481.92, triclinic, P1, a=8.127(2), b = 10\^373(2), c = 12.383(3) , α=99.51(3), β=105.47(3), γ=112.92(3)°, V=883.0(3) 3, Z=1, D c =2.787g/cm 3, F(000)= 712, μ =2.864 mm -1 , Final R =0.0368 and wR =0.0924 for 2926 reflections with I>2σ(I ). The X ray crystal structure analysis reveals that there is one independent molecule in the unit cell of the title compound which contains one centrosymmetric diacetyloctamolybdate anion, six ammonium cations and four water molecules.

关键词： diacetyloctamolybdate centrosymmetric hexakisammonium

Effects of DIMBOA on impulse discharges of maxillary lateral sensillum styloconicum of armyworm larvae

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Chinese Science Bulletin 1997年第1期42卷 72-76页

作者： Yang, dm Luo, L Yan, FM Cheng, HW Zhou, PA BEIJING UNIV COLL LIFE SCIBEIJING 100871PEOPLES R CHINA

THE DIMBOA (2, 4-dihydroxy-7-methoxy-1, 4-benzoxazin-3-one), a secondary product present in corn plants, plays an important role in protecting the plant against the pest attack. DIMBOA is rich in seedlings of cereal crops, especially in maize. Many investigators demonstrated a linear relationship between the DIMBOA content in plant and the resistance of the plant to pest. Feng et al. (1992) summarized that the toxicity of DIMBOA is associated

关键词： armyworm larvae gustatory chemoreceptor lateral sensillum styloconicum DIMBOA.