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High-resolution multi-scale air pollution system:Evaluation of modelling performance and emission control strategies

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Journal of Environmental Sciences 2024年第3期137卷 65-81页

作者： diogo lopes Joana Ferreira Sandra Rafael Ka In Hoi Xin Li Yuan Liu Ka-Veng Yuen Kai Meng Mok Ana Isabel Miranda Department of Environment and Planning&CESAM University of AveiroAveiroPortugal Department of Civil&Environmental Engineering Faculty of Science and TechnologyUniversity of MacaoMacao SARChina

A high percentage of the world's population lives in areas where air pollutant concentrations exceed the World Health Organization *** work aims to develop and test,a high-resolution multi-scale air pollution modelling system by integrating a set of adequate *** system is able to provide detailed air pollutant concentrations in urban areas and support air quality management strategies through a better identification of different atmospheric *** also allows furthering the design and assessment of air pollution control measures for a specific *** evaluate its performance and suitability,the system was applied to the Macao Special Administrative Region(SAR),China,one of the most densely populated areas on earth,during a winter period when this area is affected by high levels of Particulate Matter(PM).Although the developed system tends to underestimate the PM concentrations,it revealed a good performance in reproducing the temporal and spatial air pollution *** exceedances of the Chinese air quality standards were calculated and high population exposure to PM pollution was *** tested urban atmospheric emission reduction scenarios have shown air quality improvements,indicating that emission reduction measures at urban level should focus on the domestic ***,it is crucial to implement joint pollution prevention strategies with neighbouring regions to improve the air quality in Macao *** approach developed in this work can support policymakers in defining new strategies to reduce atmospheric pollution in urban areas.

关键词： Urban areas High-resolution emission inventory Particulate matter Population exposure

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Urban Air Quality Plans and Integrated Assessment Methodologies

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Journal of Environmental Science and Engineering(B) 2014年第2期3卷 70-78页

作者： Ana Isabel Miranda Helder Relvas Enrico Turrini diogo lopes Carlos Silveira Joana Ferreira Myriam lopes Elisa Sa Carlos Borrego Marialuisa Volta CESAM (Centre for Environmental and Marine Studies) and Department of Environmental and Planning University of Aveiro Aveiro 3810-193 Portugal Department of Mechanical and Industrial Engineering University of Brescia Brescia 25122 Italy

The air quality directive （2008/50/EC （of the European Parliament and of the Council of 21 May 2008）） requires European Member States to design appropriate AQPs （air quality plans） for zones and agglomerations where the air quality does not comply with the limit values and to assess possible emission reduction measures to decrease concentration levels. The Portuguese agglomeration of Porto Litoral is one of the several European Union urban areas that had to develop and implement AQPs to reduce particulate matter （PM10）. The AQPs were initially designed based on a scenario approach and using an air quality model, which was applied over the study region for the reference situation with the current PM10 emissions, and for a reduction scenario with PM10 emissions re-estimated considering the implementation of abatement measures. Aiming to cost-efficiently optimize Porto Litoral PM10 abatement measures, the assessment procedure was repeated using an optimization approach based on the RIAT ＋（regional integrated assessment tool ＋）. Porto Litoral urban area＇s technical and non-technical measures were characterized （including associated costs） and, through the application of the air quality model to 20 emissions abatement scenarios, S-R （source-receptor） relationships were created. This paper comparatively describes the air quality plans designed to improve PM10 levels in the Porto Litoral agglomeration based on both the scenario analysis and the optimization approach.

关键词： Urban air quality air quality plans integrated assessment methodologies modelling tools

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CAV视觉艺术中心,科英布拉,葡萄牙

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世界建筑 2006年第5期 69-73页

作者：若昂.门德斯.里贝托张婷 diogo Seixas lopes

此视觉艺术中心坐落于审判院，临近科英布拉的索菲亚大街。这条道路始建于1953年，从桑斯奥广场起始，将圣克鲁茨修道院的农场一分为二。在1548年，科英布拉大学文艺复兴改革期间，教土若昂三世下令在修道院旁边修建艺术学院。当时的主... 详细信息

此视觉艺术中心坐落于审判院，临近科英布拉的索菲亚大街。这条道路始建于1953年，从桑斯奥广场起始，将圣克鲁茨修道院的农场一分为二。在1548年，科英布拉大学文艺复兴改革期间，教土若昂三世下令在修道院旁边修建艺术学院。当时的主持者是迪奥戈·德·卡斯蒂略。但在不久之后，由于艺术学院迁到了市郊，这幢建筑便成为圣托奥菲茨法院。它直到1821年解放运动时才被废弃，当时那里还存在着当年的监狱，刑房和法庭。

关键词：艺术中心视觉 CAV 葡萄牙艺术学院文艺复兴修道院广场

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Biofloc technology (BFT): Adjusting the levels of digestible protein and digestible energy in diets of Nile tilapia juveniles raised in brackish water

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Aquaculture and Fisheries 2020年第1期5卷 42-51页

作者： Emerson Giuliani Durigon Rafael Lazzari Juliano Uczay diogo Luis de Alcântara lopes Gabriela Tomas Jerônimo Tayna Sgnaulin Maurício Gustavo Coelho Emerenciano Santa Catarina State University(UDESC) Animal Science Postgraduate Program(PPGZOO/UDESC)Chapecó88035Brazil Santa Catarina State University(UDESC) Nutrition Laboratory of Aquatic Organisms(LANOA/UDESC)Laguna 88035Brazil Santa Maria Federal University(UFSM) Animal Science and Biological Sciences DepartmentPalmeira Das MissõesPalmeira Das Missões 88035Brazil Santa Catarina Federal University(UFSC) Aquatic Organisms Health Laboratory(AQUOS)Aquaculture DepartmentFlorianópolis 88035Brazil

Several studies have been performed adjusting the levels of dietary digestible protein and digestible energy for tilapia,but none of them was performed in biofloc technology(BFT)system,especially in brackish(10)*** this sense,three levels of digestible protein(22,26 and 30%DP)and three levels of digestible energy(3000,3150 and 3300 kcal DE/kg)were evaluated on growth performance,body composition,hematological parameters and planktonic community in juveniles of Nile tilapia(***)raised under BFT conditions.A total of 540 tilapia fingerlings(GIFT strain with 1.25±0.15 g initial weight)were reared during 42 days in thirty-six plastic tanks(75 L),fed three times a *** interaction was detected in the parameters *** fish fed with feed containing 26%and 30%of DP obtained higher final weight,specific growth rate and condition factor as compared to those fed with 22%of DP(P<0.05).Body protein on tilapia carcass increased proportionally according to dietary *** higher dietary energy level promoted a higher body lipid *** to hematological parameters fish from all treatments presented a satisfactory immunological *** monitoring of planktonic community indicated a variation over time,specially on the number of dinoflagellates,rotifers and *** results indicated that diets containing 26%of DP and 3150 kcal/kg of DE for Nile tilapia juveniles promoted suitable growth performance and health conditions when reared in biofloc brackish water,and enabled savings in regards to dietary protein once the energy levels were adjusted.

关键词： Hematology Microbial floc Nursery Nutrition

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Exosomal glypican-1 is elevated in pancreatic cancer precursors and can signal genetic predisposition in the absence of endoscopic ultrasound abnormalities

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World Journal of Gastroenterology 2022年第31期28卷 4310-4327页

作者： Pedro Moutinho-Ribeiro Ines A Batista Sofia T Quintas Bárbara Adem Marco Silva Rui Morais Armando Peixoto Rosa Coelho Pedro Costa-Moreira Renato Medas Susana lopes Filipe Vilas-Boas Manuela Baptista diogo Dias-Silva Ana L Esteves Filipa Martins Joanne lopes Helena Barroca Fátima Carneiro Guilherme Macedo Sonia A Melo Serviço de Gastrenterologia Centro Hospitalar Universitário de Sao JoaoPorto 4200Portugal Faculty of Medicine University of PortoPorto 4200Portugal Instituto de Investigacao e Inovacao em Saúde(i3S) Universidade do PortoPorto 4200Portugal IPATIMUP-Institute of Molecular Pathology and Immunology University of PortoPorto 4200Portugal Instituto de Ciencias Biomédicas Abel Salazar(ICBAS) University of PortoPorto 4050Portugal Servico de Cirurgia Geral Centro Hospitalar Universitário de Sao JoaoPorto 4200Portugal Unidade de Saúde Familiar Serpa Pinto ACeS Porto OcidentalPorto 4250Portugal Serviço de Anatomia Patológica Centro Hospitalar Universitário de Sao JoaoPorto 4200Portugal

BACKGROUND Individuals within specific risk groups for pancreatic ductal adenocarcinoma(PDAC)[mucinous cystic lesions(MCLs),hereditary risk(HR),and new-late onset diabetes mellitus(NLOD)]represent an opportunity for early cancer *** ultrasound(EUS)is a premium image modality for PDAC screening and precursor lesion *** no specific biomarker is currently clinically available for this purpose,glypican-1(GPC1)is overexpressed in the circulating exosomes(crExos)of patients with PDAC compared with healthy subjects or those harboring benign pancreatic *** To evaluate the capacity of GPC1+crExos to identify individuals at higher risk within these specific groups,all characterized by *** This cross-sectional study with a prospective unicentric cohort included 88 subjects:40 patients with MCL,20 individuals with HR,and 20 patients with NLOD.A control group(CG)was submitted to EUS for other reasons than pancreatic pathology,with normal pancreas and absence of hereditary risk factors(n=8).The inclusion period was between October 2016 and January 2019,and the study was approved by the Ethics Committee of Centro Hospitalar Universitário de São João,Porto,*** patients provided written informed *** and blood tests for quantification of GPC1+crExos by flow cytometry and carbohydrate antigen 19-9(CA 19-9)levels by ELISA were performed in all ***-guided tissue acquisition was done whenever *** statistical analysis,SPSS®27.0(IBM Corp.,Armonk,NY,United States)version was *** graphs were created using GraphPad Prism 7.00(GraphPad Software,San Diego,CA,United States).RESULTS Half of MCLs harbored worrisome features(WF)or high-risk stigmata(HRS).Pancreatic abnormalities were detected by EUS in 10.0%and 35.0%in HR and NLOD individuals,respectively,all considered non-malignant and“harmless.”Median levels of GPC1+crExos were statistically different:MCL[99.4%,interquartile range(IQR):94.9%-99.8%],HR(8

关键词： Glypican-1 Circulating exosomes Endoscopic ultrasound Pancreatic cancer risk groups Pancreatic cancer precursor lesions Genetic predisposition

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Tuberculosis Presenting as Multiple Vein Thrombosis in a Hospitalized Man

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Journal of Tuberculosis Research 2020年第3期8卷 177-180页

作者： Neuza Soares Mariana Pacheco João Rocha diogo José M. lopes Rodrigo Correia Inês Silva Internal Medicine Department Centro Hospitalar Universitário de Sa&#227 oJoaã o Porto Portugal Clinical Pharmacology Unit Centro Hospitalar Universitário de Sa&#227 oJoaã o Porto Portugal Physical Medicine and Rehabilitation Deparment Centro Hospitalar Vila Nova de Gaia/Espinho Gaia Portugal

Tuberculosis (TB) remains an infectious disease with a high prevalence worldwide and represents a major public health issue. Although venous thromboembolism (VTE) is a rare complication of this disease, it may be a potentially life-threatening event. A 58-year-old man was admitted due to hematemesis due to inflammation at the anastomosis site after a gastrectomy years ago. After 3 days in-hospital, he showed a peroneal deep vein thrombosis and superficial thrombosis of left cephalic vein. Although reduced mobility and lack of prophylactic heparin could explain vein thrombosis, a simple etiologic workup was performed and active tuberculosis was diagnosed. This case illustrates a rare and unusual presentation form of tuberculosis, a condition that remains now-a-days one of the leading infectious causes of death worldwide. The association between tuberculosis and VTE is rare, but it should be systematically investigated.

关键词： Pulmonary Tuberculosis Thrombosis Hypercoagulable State

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Determining the Levels of Trace Elements Cd, Cu, Pb and Zn in Honey of Stingless Bee (Hymenoptera: Apidae) Using Voltammetry

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Food and Nutrition Sciences 2015年第7期6卷 591-596页

作者： Andreia Santos do Nascimento Luis Carlos Marchini Carlos Alfredo lopes de Carvalho diogo Feliciano Dias Araújo Talita Antonia da Silveira Ricardo Alves de Olinda Departamento de Entomologia e Acarologia Escola Superior de Agricultura “Luiz de Queiroz” Universidade de S&atilde o Paulo Piracicaba Brazil Centro de Ciências Agrárias Ambientais e Biológicas Universidade Federal do Rec&ocirc ncavo da Bahia Cruz das Almas Brazil Departamento de Estatística Centro de Ciência e Tecnologia Universidade Estadual da Paraíba Bodocongó Brazil

Determining the levels of heavy metals in honey is a measure to control its quality. The objective of this study was to determine the contents of Cd, Cu, Pb and Zn in honey of stingless bee. The differential pulse anodic stripping voltammetry (DPASV) was used to determine the trace elements in honey samples. Pb was detected in 100% of the samples, Cu and Zn in 98.15%, and Cd only in 33.33%. The trace elements analyzed detected in the samples remained within tolerable levels in foods for human consumption.

关键词： Heavy Metals Stingless Bees Voltammetry Honey

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Partial Nephrectomy as Treatment of an Atypical Metastasis from Prostate Cancer—A Case Report and Review of Literature

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Open Journal of Urology 2018年第1期8卷 8-16页

作者： Ulisses lopes Guerra Pereira Sobrinho André Luiz Lima Diniz Rodrigo Galves Mesquita Martins diogo Eugenio Abreu Da Silva Tomás Accioly De Souza José Anacleto Dutra De Resende Júnior Department of Urology Lagoa Federal Hospital Rio de Janeiro Brazil

Background: Prostate cancer is the second most common type of cancer in man and the second in cancer-specific deaths in this population in the world. Most of the causes of death related to prostate cancer are due to its distant metastases, with the most common sites being: skeleton, distant lymph nodes, liver and lung. Renal metastasis is rare, and studies suggest infiltration due to arterial microembolization of the tumor. A key point in this scenario is the clinical suspicion of differential diagnoses, to offer the patient an effective therapy in such a specific case. Aim: To report a case of a patient with prostate cancer undergoing partial nephrectomy whose histopathological report revealed a metastatic lesion of that primary site. Case Presentation: 74 years old man, referred in May 2015 due to high PSA level and lumbago. PSA 323.11 ng/dl, rectal examination cT3a;biopsy was performed and histopathological study reported bilateral prostate adenocarcinoma, Gleason’s score 8 (4 + 4). Patient’s staging showed multiple secondary implants on skeletal scintigraphy. Tomography revealed solid exophytic lesion in the lower pole of the right kidney (4.7 × 3.6 cm);prostate without cleavage planes with seminal vesicles and pelvic node enlargement. Hormone therapy was initiated, PSA levels dropped to 9.51 ng/dl and total testosterone Conclusion: Given the rarity of these cases, it is not possible to presume that nephrectomy enhances the survival rates. However, we observed that partial nephrectomy was a good choice for our patient, being the first case described in the literature. More reports should be available and studies with higher levels of evidence should be conducted to assist us in patient orientation and decision making.

关键词： Advanced Prostate Cancer Kidney Metastasis Partial Nephrectomy

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