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Zinc:an essential trace element for human health and beyond

Food and Health 2023年第3期5卷 12-18页

作者： Rohit Patil Tejswini Sontakke Ashwini Biradar dinesh Nalage Department of Botany Government Institute of ScienceAurangabad 431004India Department of Zoology MGV'sMPH Mahila CollegeMalegaon 423105India Department of Microbiology Dr.B.A.M.UniversitySub Campus OsmanabadOsmanabad 413501India Department of Molecular Biology&Microbiology One Step Molecular DiagnosticAurangabad 431003India

Zinc is an essential element that plays a crucial role in the chemistry and biochemistry of living *** serves as a cofactor for numerous enzymes and transcription factors,contributing to DNA synthesis,protein synthesis and cellular ***,zinc acts as a structural component of proteins and participates in cellular signaling *** chemistry of zinc is determined by its electronic configuration,and it readily forms coordination complexes with various *** review explores the diverse functions of zinc in the body,including its involvement in enzyme activity,immunity,neutrophil function,modulation of allergies,its relationship with COVID-19,antioxidant and anti-inflammatory properties,mental health,pregnancy and wound *** has a history of use in traditional medicine systems,and its benefits and applications should be evaluated in the context of current scientific research and medical *** the roles of zinc in these processes highlights its importance as an essential nutrient for overall health and provides insights into potential therapeutic ***,further advancement in understanding the biological function of zinc requires addressing certain *** include overcoming methodological challenges,investigating tissue and cell-type specificity,understanding zinc interactions and redundancy,and employing integrated approaches,advanced imaging techniques,comparative studies,and systems biology approaches to gain a deeper understanding of zinc’s implications in health and disease.

关键词： zinc biochemistry deficiency immune system enzymes

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印刷技术的兴起及其在斯里兰卡文化形成中的作用

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印刷文化（中英文） 2021年第3期 167-176页

作者：迪纳什·库拉通加国际儿童读物联盟(IBBY)斯里兰卡分会 “阅读+”基金会海王星出版物(PVT)有限公司斯里兰卡印刷媒体学院

斯里兰卡在1948年独立前被称为"锡兰",有着悠久的书写和学习传统,书籍主要是用铁笔在棕榈叶上刻划写成。佛教僧侣使用这些"棕榈叶手稿"(也称"贝叶经")来传授佛教经义。荷兰是此地的第二任殖民者,它对斯里兰卡的殖民统治到1796年被英国... 详细信息

斯里兰卡在1948年独立前被称为"锡兰",有着悠久的书写和学习传统,书籍主要是用铁笔在棕榈叶上刻划写成。佛教僧侣使用这些"棕榈叶手稿"(也称"贝叶经")来传授佛教经义。荷兰是此地的第二任殖民者,它对斯里兰卡的殖民统治到1796年被英国接管为止。1736年,荷兰人在殖民期间将近代活字印刷文化带到了斯里兰卡。此后,多名天主教传教士建立了多个印刷厂,用以传播他们的宗教信仰,并让当地僧伽罗佛教徒改信天主教。尔后,荷兰政府也建立了政府出版印刷机构,后来由英国殖民者接手,1948年斯里兰卡独立后仍由政府经营。直到1862年,僧伽罗佛教徒首次进口了一台印刷机,这才打破了200多年的沉默局面。此后,斯里兰卡又成立许多家出版社,用以印刷宗教类和教育类书籍,直接与其他宗教宣传竞争,并对当地社会产生了影响,从而开始在许多领域塑造人们的思想。1818年和1848年斯里兰卡爆发两次反英起义后,为了服务政府、农业和贸易部门,政府与私营出版社开始出版报纸,这些报纸对社会产生了强烈的影响,催生了教育需求。19世纪的印刷机和印刷文化促发了教育革命,最终改变了这个国家。

关键词：斯里兰卡僧伽罗语传教士棕榈叶手稿印刷机

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含笑属植物所含化学成分与其生物活性的综述(英文)

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中西医结合学报 2012年第12期10卷 1336-1340页

作者： dinesh kumar Sunil kumar Seema Taprial Deepak kashyap Ajay kumar Om Prakash Institute of Pharmaceutical Sciences Kurukshetra University

属木兰科的含笑属植物大约有80多个种类,它们大都分布在南亚国家。这些植物被当地人用于治疗各种疾病,如发烧、绞痛、麻风病、眼疾、炎症以及解蝎子毒。从9种含笑属植物中分离出94种化合物,例如倍半萜烯、类固醇、黄酮类、阿扑啡类、苯... 详细信息

属木兰科的含笑属植物大约有80多个种类,它们大都分布在南亚国家。这些植物被当地人用于治疗各种疾病,如发烧、绞痛、麻风病、眼疾、炎症以及解蝎子毒。从9种含笑属植物中分离出94种化合物,例如倍半萜烯、类固醇、黄酮类、阿扑啡类、苯酚、酯类、生物碱和苯环型化合物等,它们具有抗菌、抗癌以及抗疟原虫活性。本文详细地论述了含笑属植物所含化学成分的生物及化学性能。

关键词：含笑属药理作用综述

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Antidiabetic activity of methanolic bark extract of Alhizia odoratissima *** alloxan induced diabetic albino mice

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Asian Pacific Journal of Tropical Medicine 2011年第11期4卷 900-903页

作者： dinesh kumar Sunil kumar Sonia kohli Renu Arya Jyoti Gupta Institute of Pharmaceutical Sciences Kurukshetra UniversityKurukshetra-136119HaryanaIndia

Objective:To evaluate the antidiabetic potential of methanolic extract of Albizia odoratissima *** in alloxan induced diabetic ***:Group-Ⅰ(normal control) mice received only basal diet without any *** Group-Ⅱ(Diabetic control) mice,diabetes was induced by alloxan(150 mg/kg i.p.) and received only Tween 80.5%v/v in normal saline. Group-Ⅲand Group-Ⅳmice received metformin(10 mg/kg) and gliclazide(10 mg/kg) as standard ***-ⅤandⅥmice received methanolic bark extract of Albizia odoratissima at doses of 250 and 500 mg/kg body weight p.o.,***:The results of the study indicates that Albizia odoratissima bark extract significantly(Pk extract also significantly reduced the levels of serum cholesterol,triglycerides, serum glutamic-oxaloacetic transaminase,serum glutamic-pyruvic transaminase,alkaline phosphatase and decreases level of total proteins in alloxan induced diabetic ***: Methanolic extract of Albizia odoratissima has protective effects on the protection of vital tissues(pancreas,kidney,liver,heart and spleen),thereby reducing the causation of diabetes in experimental animals.

关键词： Albizia odoratissima Antidiabetic potential Methanolic extract Alloxan Mice

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Impact of Environmental,Social,and Governance(ESG)Factors on Stock Prices and Investment Performance

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Macro Management & Public Policies 2023年第2期5卷 14-26页

作者： Abhinandan kulal Abhishek N Sahana dinesh Divyashree M.S. Department of Commerce University Evening CollegeMangalore575001India Institute of Management and Commerce Srinivas UniversityMangalore574146India Department of Commerce Field Marshal K M Cariappa CollegeMadikeri571201India Department of Commerce GFGCUppinangadyMangalore574241India

This study examines the relationship between Environmental,Social,and Governance(ESG)factors and stock prices as well as investment *** factors have become increasingly relevant in investment decisions as investors prioritize companies with sustainable *** a sample of publicly-traded companies,this research analyzes the impact of ESG factors on stock prices and investment *** findings suggest that companies with strong ESG performance tend to have higher stock prices and better investment performance than those with weak ESG *** study also highlights the significance of the individual components of ESG,such as environmental policies and corporate governance practices,on stock prices and investment ***,this research provides valuable insights for investors seeking to incorporate ESG factors into their investment decision-making processes.

关键词： ESG factors Stock price Investment performance

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Improvement of Bio-Efficacy to Reduce Bacterial Wilt Complex Disease in Tomatoes through Bacillus amyloliquefaciens and Pseudomonas fluorescens under Field Conditions

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Journal of Agricultural Science and Technology(B) 2021年第3期11卷 109-120页

作者： dinesh Singh Dhananajay kumar Yadav Harender kumar Sharma Garima Chaudhary Division of Plant Pathology ICAR-Indian Agricultural Research InstituteNew Delhi 110012India Division of Nematology ICAR-Indian Agricultural Research InstituteNew Delhi 110012India

Bacterial wilt complex disease of tomato(Solanum lycopersicum L.)was incited jointly by bacterial wilt pathogen Ralstonia solanacearum and Meloidogyne incognita ***-efficacy of bacterial antagonists *** DSBA-11 and *** DTPF-3 was studied against the wilt disease complex in tomato at National Phytotran facility Indian Agricultural Research Institute(IARI),New Delhi,at 26±2°*** wilt disease incidence(26.00%)with the highest bio-control efficacy(64.15%),less juvenile population(19.33 J2/g of soil)of *** was recorded in the combined application of DTPF-3+DSBA-11 after 30 d of inoculation under glasshouse *** a field study,minimum bacterial wilt disease incidences 19.0%and 20.4%were recorded in the bleaching powder treatment followed by mixed application of DSBA-11+DTPF-3,19.6%and 21.2%wilt incidence in 2014 and 2015 ***,a reduction of root-knot gall index was recorded a maximum of 59.76%and 69.62%in DSBA-11+DTPF-3 treated plants followed by 54.88%and 60.13%over control in DTPF-3 treatment in 2014 and 2015 *** yield of tomato fruit was increased over control by 17.48%and 16.97%in 2014 and 2015 respectively under field conditions.A combination of *** DTPF-3+*** DSBA-11 suppressed bacterial wilt and root-knot diseases and also increased the yield of the tomato fruit significantly(p<0.05)under field conditions.

关键词： Bacillus amyloliquefaciens bacterial wilt complex Meloidogyne incognita Ralstonia solanacearum Pseudomonas fluorescens tomato

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4种方法提取金黄色葡萄球菌基因DNA效果的比较

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生物医学 2019年第4期9卷 154-161页

作者：邹治情张敏戴晓玥夏雯周亚玲何蕾白佳玉苏叶 dinesh kumarkesavan 吴亮阴晴许化溪江苏大学医学院江苏镇江江苏大学附属医院江苏镇江

目的:比较4种方法,包括煮沸法、改良碱裂解法、磁珠法和吸附柱法提取金黄色葡萄球菌基因DNA效果,为临床金黄色葡萄球菌感染的快速检测提供技术支撑。方法:选取20株临床分离耐甲氧西林的金黄色葡萄球菌,分别使用煮沸法、改良碱裂解法、... 详细信息

目的:比较4种方法,包括煮沸法、改良碱裂解法、磁珠法和吸附柱法提取金黄色葡萄球菌基因DNA效果,为临床金黄色葡萄球菌感染的快速检测提供技术支撑。方法:选取20株临床分离耐甲氧西林的金黄色葡萄球菌,分别使用煮沸法、改良碱裂解法、磁珠法和吸附柱法提取基因DNA。通过PCR法扩增所提取DNA模板中金黄色葡萄球菌spa基因、mecA基因和femB基因,以评估4种方法提取效果。结果:磁珠法制备的模板中,PCR法可以扩增出所有标本的spa基因、mecA基因和femB基因;吸附柱法制备的模板中,所有标本均可扩增出spa基因和mecA基因,而仅19个标本扩增出femB基因;以改良手工碱裂解法制备的模板,所有标本均可扩增出mecA基因,19标本可以扩增出spa基因和femB基因;煮沸法制备的模板中,PCR法可以分别扩增出7个标本的spa基因,8个标本的mecA基因,所有标本均未扩增出femB基因。结论:改良碱裂解法、吸附柱法和磁珠法提取金黄色葡萄球菌基因组DNA均可以用于PCR扩增,直接煮沸法提取效果较差,不适合用于临床金黄色葡萄球菌基因组DNA提取;磁珠法用时最短,更适合于大量快速自动化提取。

关键词：金黄色葡萄球菌 DNA提取 PCR检测

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A slight glance at peer review

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World Journal of Surgical Procedures 2018年第1期8卷 1-5页

作者： Neil D Joshi kaivalya S Deshpande Christian W Roehmer dinesh Vyas Department of Surgery Michigan State University College of Human Medicine Department of Surgery San Joaquin General Hospital French Camp

In order to ensure that the highest quality of literature is published, most journals utilize a peer review process for manuscripts submitted. Although the primary purpose for this process is to filter out "bad science", the process is not perfect. While there is a general consensus among researchers and clinicians that something must be done to improve upon the method for properly vetting manuscripts, there are conflicting opinions on how to best implement new policies. In this paper, we discuss the most well-supported suggestions to improve the process, with the hopes of increasing rigor and reproducibility, ensuring double-blinding, developing set guidelines, offering early training to reviewers, and giving reviewers better feedback and recognition for their work.

关键词： Peer review Bias Double-blind method Conflict of interest Misconduct

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屏风住宅印度勒克瑙私宅

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室内设计与装修 2020年第7期 80-83页

作者：麦子(编译) 无 Nina Puri Sanjay Puri Ruchika Gupta Jinal Jain Nivedita Raverkar Nandita Rebello Akanksha Singh Swati Gadekar dinesh Mehta(摄影) 不详 Nina&Sanjay Puri Architects

印度勒克瑙城拥有丰富的历史文化遗产,许多建筑都可追溯到18世纪。本文介绍的这幢住宅位于该市繁忙的主干道边,是一片私人住宅地块的边缘部分。项目采用了印度传统四合院的建筑形制,以回应城市特征和炎热的气候条件。业主希望在这个两... 详细信息

印度勒克瑙城拥有丰富的历史文化遗产,许多建筑都可追溯到18世纪。本文介绍的这幢住宅位于该市繁忙的主干道边,是一片私人住宅地块的边缘部分。项目采用了印度传统四合院的建筑形制,以回应城市特征和炎热的气候条件。业主希望在这个两层高的通风庭院中穿插设置一些有遮挡的开放式露台和景观花园。同时,除了6间卧室之外,还需要普伽室、书房、影视室以及多功能区域等,并希望这些空间均能通往露台和景观花园。

关键词：私人住宅建筑形制露台历史文化遗产传统四合院屏风边缘部分勒克瑙

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Adenosine triphosphate induced cell death: Mechanisms and implications in cancer biology and therapy

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World Journal of Clinical Oncology 2023年第12期14卷 549-569页

作者： Hao-Ling Zhang Doblin Sandai Zhong-Wen Zhang Zhi-Jing Song dinesh Babu Yasser Tabana Sabbar Saad Dahham Mowaffaq Adam Ahmed Adam Yong Wang Wei Wang Hao-Long Zhang Rui Zhao khaled Barakat Mohammad Syamsul Reza Harun Siti Nurfatimah Mohd Shapudin Bronwyn Lok Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia School of Public Health Gansu University of Chinese MedicineLanzhou 730000Gansu ProvinceChina Clinical College of Chinese Medicine Gansu University of Chinese MedicineLanzhou 730000Gansu ProvinceChina Faculty of Pharmacy and Pharmaceutical Sciences University of AlbertaEdmonton AB T6G 2E1Canada Department of Science University of Technology and Applied Sciences RustaqRustaq 10 P.C.329Oman Department of Chemistry and Biochemistry San Diego State UniversitySan DiegoCA 92182United States Pathology Center Gansu University of Chinese MedicineLanzhou 730000Gansu ProvinceChina College of Acupuncture-Moxibustion and Tuina Gansu University of Chinese MedicineLanzhou 730000Gansu ProvinceChina

Adenosine triphosphate(ATP)induced cell death(AICD)is a critical cellular process that has garnered substantial scientific interest for its profound relevance to cancer biology and to therapeutic *** comprehensive review unveils the intricate web of AICD mechanisms and their intricate connections with cancer *** review offers a comprehensive framework for comprehending the multifaceted role of AICD in the context of *** is achieved by elucidating the dynamic interplay between systemic and cellular ATP homeostasis,deciphering the intricate mechanisms governing AICD,elucidating its intricate involvement in cancer signaling pathways,and scrutinizing validated key ***,the exploration of AICD as a potential avenue for cancer treatment underscores its essential role in shaping the future landscape of cancer therapeutics.

关键词： Adenosine triphosphate induced cell death Adenosine triphosphate homeostasis Mechanism Cancer signaling pathways Prognosis and clinical values Cancer treatment

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