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Contemporary indications for and outcomes of hepatic resection for neuroendocrine liver metastases

World Journal of Gastrointestinal Surgery 2020年第4期12卷 159-170页

作者： Steven D Scoville dimitrios xourafas Aslam M Ejaz Allan Tsung Timothy Pawlik Jordan M Cloyd Department of Surgery Division of Surgical Oncology at The Ohio State UniversityJames Cancer CenterColumbusOH 43210United States The Arthur G James Comprehensive Cancer Center and Solove Research Institute The Ohio State UniversityColumbusOH 43210United States Department of Surgery Harvard Medical SchoolDepartment of SurgeryBrigham and Women's HospitalHarvard Medical SchoolBostonMA 02215United States Department of Surgery The Ohio State UniversityColumbusOH 43210United States Department of Surgery The Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Surgery Division of Surgical OncologyThe Ohio State University Wexner Medical CenterColumbusOH 43210United States

BACKGROUND Although surgical resection is associated with the best long-term outcomes for neuroendocrine liver metastases(NELM),the current indications for and outcomes of surgery for NELM from a population perspective are not well *** To determine the current indications for and outcomes of liver resection(LR)for NELM using a population-based *** A retrospective review of the 2014-2017 American College of Surgeons National Surgical Quality Improvement Program and targeted hepatectomy databases was performed to identify patients who underwent LR for *** characteristics and 30-d morbidity and mortality were *** Among 669 patients who underwent LR for NELM,the median age was 60(interquartile range:51-67)and 51%were *** the number of metastases resected ranged from 1 to 9,the most common(45%)number of tumors resected was *** majority(68%)of patients had a largest tumor size of230 min(OR=1.731,95%CI:1.168-2.565)were associated with higher 30-d morbidity while intraoperative ablation and concomitant procedures were *** LR for NELM was performed with relatively low postoperative morbidity and *** procedures performed at the time of LR did not increase morbidity.

关键词： Carcinoid Neuroendocrine tumor Primary tumor resection Intraoperative ablation Cholecystectomy Small bowel resection

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