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Colorectal cancer,screening and primary care: A mini literature review

World Journal of Gastroenterology 2017年第33期23卷 6049-6058页

作者： Athanasios Hadjipetrou dimitrios anyfantakis Christos G Galanakis Miltiades Kastanakis Serafim Kastanakis Primary Health Care Centre of Kissamos First Department of Surgery Saint George General Hospital of Chania Private Family Practice Unit in Chania Department of Internal Medicine Saint George General Hospital of Chania

Colorectal cancer(CRC) is a common health problem,representing the third most commonly diagnosed cancer worldwide and causing a significant burden in terms of morbidity and mortality,with annual deaths estimated at 700000. The western way of life,that is being rapidly adopted in many regions of the world,is a well discussed risk factor for CRC and could be targeted in terms of primary prevention. Furthermore,the relatively slow development of this cancer permits drastic reduction of incidence and mortality through secondary prevention. These facts underlie primary care physicians(PCPs) being assigned a key role in health strategies that enhance prevention and prompt diagnosis. Herein,we review the main topics of CRC in the current literature,in order to better understand its pathogenesis,risk and protective factors,as well as screening techniques. Furthermore,we discuss preventive and screening policies to combat CRC and the crucial role served by PCPs in their successful implementation. Relevant articles were identified through electronic searches of MEDLINE and through manual searches of reference lists.

关键词： Colorectal cancer Prevention Diagnosis Screening Primary care

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评估冷冻手术治疗面部肉芽肿的有效性

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世界核心医学期刊文摘（皮肤病学分册） 2006年第6期2卷 33-33页

作者： Panagiotopoulos A. anyfantakis V. Rallis E. 罗素菊 Department of Cryosurgery 'A. Sygros'Hospital 5I. Dragoumi Str 16121 Athens Greece Dr.

Background: Granuloma faciale (GF) is an uncommon dermatosis of unknown pathogenesis. Multiple treatments have been proposed with varying results. We report nine cases treated successfully with cryosurgery and we review the literature. Objectives: To study the efficacy, tolerability and safety of cryosurgery techniques in the treatment of GF. Methods: Nine immunocompetent adults with GF were treated by cryosurgery. The initiation of the therapy was preceded by a 60-day washout period in all subjects using other medication. Two different techniques were used (open-spray and contact cryo-probe). Results: All patients were treated successfully. Apart from mild postinflammatory hypopigmentation in two patients that resolved within 4 months, no other adverse event was mentioned. During an average 24-month follow-up period after the integration of therapy, no recurrences were observed. Conclusions: Cryosurgery is an efficient, safe, inexpensive, easily used method for this uncommon dermatosis, which can be proposed as a treatment of first intention.

关键词：手术治疗冷冻手术肉芽肿面部发病机制手术技术其他药物停止使用冷冻探针色素减退

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“Dalmatian狗”样斑疹——由甲芬那酸引起的多发性固定药疹2例

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世界核心医学期刊文摘（皮肤病学分册） 2006年第4期2卷 19-19页

作者： Rallis E. Rigopoulos D. anyfantakis V. 李翠华 Department of Dermatology University ofAthens ‘ A. Sygros’ Hospital 5 I.Dragoumi St. 16121 AthensGreece

Mefenamic acid is a commonwidely prescribed drugwith analgesic activity. Authors report two cases ofmultifocal fixed drug eruption induced by mefenamic acid. Cases were diagnosed on basis of clinical examination and histopathol-ogy of skin lesion. Only a few cases have been reported in the literature and these are the first two described in Greece.

关键词： Dalmatian 甲芬那酸皮损组织病理

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