检索结果-南通市图书馆

Description of a Propulsion Unit Used in Guiding a Walking Machine by Recognizing a Three-point Bordered Path

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2016年第6期29卷 1157-1166页

作者： NUNEZ-ALTAMIRANO diego A JUAREZ-CAMPOS Ignacio MARQUEZ-PEREZ Lucia FLORES-DIAZ Ociel School of Mechanical Engineering Universidad Michoacana de San Nicolas de Hidalgo Morelia Michoacan Mexico

A reconfigurable propulsion unit based on the Peaucellier-Lipkin mechanism has the ability to describe exact straight or curved paths depending on the selected ratio between the lengths of two of its links. The Peaucellier-Lipkin mechanism with one degree of freedom is transformed into a more sophisticated parallel kinematic chain by including four more degrees of freedom. The resulting propulsion unit is able to adapt its kinematic structure and reach instant centers of rotation, in accordance with the presence of three points that border a geometric path. A laser sensor mounted on the body of the machine detects each point. Once the machine has detected the exact location of the border of the road, it walks along a curve parallel to that border. Although the proposed research describes only one propulsion unit or leg, the methodology can be applied to all the legs of the walking machine. The novel 5-DOF leg is able to reach different centers of rotation, providing either the concave or convex arcs that satisfy the basic principle of displacement of walking machines.

关键词： Propulsion unit Peaucellier-Lipkin walking machine straight line mechanism.

Celeboxib-mediated neuroprotection in focal cerebral ischemia: an interplay between unfolded protein response and inflammation

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第2期17卷 302-303页

作者： Maria Santos-Galdiano diego Perez-Rodriguez Arsenio Fernandez-Lopez Area de Biologia Celular Instituto de BiomedicinaCampus de Vegazana s/nUniversidad de LeonLeonSpain Neural Therapies SL Campus de Vegazana s/nLeónSpain Department of Clinical and Movement Neurosciences UCL Queen Square Institute of NeurologyLondonUK

Ischemic stroke results from the temporary or permanent lack of blood supply in the brain due to the occlusion of a brain blood vessel. Around 85% of patients with cerebrovascular accidents suffer from ischemic strokes.

关键词： inflammation cerebral ischemia

Freely Available Tool(FAT)for automated quantification of lipid droplets in stained cells

在线全文

学校读者我要写书评

暂无评论

BIOCELL 2017年第2期41卷 55-58页

作者： diego MASONE ALDANA DGOJANOVICH YESICA R.FRONTINI-LOPEZ SAMANTA DEL VELIZ MARINA UHART diego M.BUSTOS Laboratorio de Integración de Senales Celulares.IHEM-CONICET Universidad Nacional de Cuyo MendozaArgentina Facultad de Ingeniería Universidad Nacional de CuyoMendozaArgentina Facultad de Ciencias Exactas y Naturales Universidad Nacional de CuyoMendozaArgentina

In this study,we propose an automatic procedure for digital image *** describe a method that can efficiently quantify and characterize lipid droplets distributions in different cell types in ***,the lipid droplets detection method described in this work could be applied to static or time-lapse data,collected with a simple visible light or fluorescence microscopy *** automated algorithms were implemented in Octave,a freely available scientific package.

关键词： Adipogenesis 3T3-L1 cells human stem cells automatic image processing

Phenomenological Based Soft Sensor for Online Estimation of Slurry Rheological Properties

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Automation and computing 2019年第5期16卷 696-706页

作者： Jenny L.Diaz C. diego A.Munoz Hernan Alvarez Research Group of Dynamic Processes Universidad Nacional de Colombia-Sede MedellínFacultad de Minas.Cra 80Medellín 65-223Colombia Mathematical Optimization of Processes Centro de Ciencia BásicaUniversidad Pontificia BolivarianaCircular 1Medellín 70-01Colombia

This work proposes a soft sensor based on a phenomenological model for online estimation of the density and viscosity of a slurry flowing through a pipe-and-fittings assembly(PFA). The model is developed considering the conservation principle applied to mass and momentum transfer and considering frictional energy losses to include the variables directly affecting slurry properties. A reported proposal for state observers with unknown inputs is used to develop the first block of the observer structure. The second block is constructed with two options for evaluating slurry viscosity, generating two possible estimator structures, which are tested using real data. A comparison between them indicates different uses and capabilities according to available process information.

关键词： Soft sensor phenomenological based semi-physical model non-Newtonian fluids unknown input observer slurry flow

Acoustic micro‐beam vortex generator for flow actuation inside droplets

在线全文

学校读者我要写书评

暂无评论

Droplet 2024年第1期3卷 125-135页

作者： diego Sánchez‐Saldaña Maria Fernandino Carlos A.Dorao Department of Energy and Process Engineering Norwegian University of Science and TechnologyTrondheimNorway

Controlling acoustic streaming inside a droplet has excellent potential for enabling fluid and particle operations such as mixing,separation,and aggregation in various *** concepts for generating surface acoustic waves are based on the placement of an interdigitated transducer at the side of a droplet,thus externally acting on the *** this case,the flow structure inside the droplet is controlled by the relatively large scale of the interdigitated transducer compared to the droplet,thus limiting the local control of the *** possibility to overcome this drawback is to reduce the size of the actuator such that a highly focused ultrasound transducer can induce localized acoustic streaming in ***,we introduce a micro‐spiral interdigitated transducer smaller than a droplet size that can generate micro‐size vortices inside the *** step enables a new way of controlling the flow inside the droplet,facilitating mixing,separation,aggregation,and patterning of *** study the characteristics of the acoustic streaming and the potential application of the flow for the separation and patterning of *** simplicity of the concept provides in‐droplet particle manipulation toolsets for many applications such as biosensing,microbiology,and point‐of‐care devices.

关键词： flow separation aggregation

Applied RCM^2 Algorithms Based on Statistical Methods

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Automation and computing 2007年第2期4卷 109-116页

作者： Fausto Pedro García Márquez diego J. Pedregal ETSI Industriales Universidad de Castilla-La ManchaCampus Universitario s/n 13071 Ciudad RealSpain

The main purpose of this paper is to implement a system capable of detecting faults in railway point mechanisms. This is achieved by developing an algorithm that takes advantage of three empirical criteria simultaneously capable of detecting faults from records of measurements of force against time. The system is dynamic in several respects： the base reference data is computed using all the curves free from faults as they are encountered in the experimental data; the algorithm that uses the three criteria simultaneously may be applied in on-line situations as each new data point becomes available; and recursive algorithms are applied to filter noise from the raw data in an automatic way. Encouraging results are found in practice when the system is applied to a number of experiments carried out by an industrial sponsor.

关键词： Maintenance railways state space models system reliability monitoring elements.

Bulk flow properties of fly ashes at ambient and high temperature

在线全文

学校读者我要写书评

暂无评论

Particuology 2018年第3期16卷 113-125页

作者： Yi Liu Haifeng Lu diego Barletta Massimo Poletto Xiaolei Guo Xin Gong YongJin Key Laboratory of Coal Gasification and Energy Chemical Engineering of the Ministry of Education Shanghai Engineering Research Center of Coal Gasification Institute of Clean Coal Technology East China University of Science and Technology Shanghai 200237 China Dipartimento di lngegneria lndustriale Universita degli Studi di Salerno Via Giovanni Paolo II 1321-84084 Fisciano SA Italy

The bulk flow properties of four different fly ashes were assessed at ambient temperature and at 500 ~C, using a high temperature annular shear cell. These powders all resulted from industrial processes and had similar chemical compositions but different particle size distributions. Applying a high temperature was found to increase the powder cohesion, with this effect being more significant in the case of the sample with the highest proportion of fines. To better understand the effect of temperature on the bulk flow properties of these materials, a model previously proposed by some of the authors was used to correlate the powder isostatic tensile strength with the interparticle forces and microscale particle contact struc- ture. This model combines the continuum approach with description of particle-to-particle interactions. A comparison with experimental data indicated that the effects of consolidation and temperature on the tensile strength of the fly ashes were correctly described by the model. This theoretical approach also elucidates the mechanism by which the temperature affects the bulk flow properties of fly ashes through modifications of the microscale intemarticle contacts.

关键词： Fly ash High temperature annular-shear cell Flow model Isostatic tensile strength Interparticle force

Magnetohydrostatic modeling of the solar atmosphere

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2022年第8期65卷 1710-1726页

作者： ZHU XiaoShuai NEUKIRCH thomas WIEGELMANN thomas State Key Laboratory of Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Mathematics and Statistics University of St AndrewsSt Andrews KY169SSUK Max-Planck-Institut f¨ur Sonnensystemforschung G¨ottingen 37077Germany

Understanding structures and evolutions of the magnetic fields and plasma in multiple layers on the Sun is very important. A force-free magnetic field which is an accurate approximation of the solar corona due to the low plasma β has been widely studied and used to model the coronal magnetic structure. While the force-freeness assumption is well satisfied in the solar corona, the lower atmosphere is not force-free given the high plasma β. Therefore, a magnetohydrostatic(MHS) equilibrium which takes into account plasma forces, such as pressure gradient and gravitational force, is considered to be more appropriate to describe the lower atmosphere. This paper reviews both analytical and numerical extrapolation methods based on the MHS assumption for calculating the magnetic fields and plasma in the solar atmosphere from measured magnetograms.

关键词： magnetic field photosphere chromosphere corona

Autoimmune hepatitis: standard treatment and systematic review of alternative treatments

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第33期23卷 6030-6048页

作者： Benedetta Terziroli Beretta-Piccoli Giorgina Mieli-Vergani diego Vergani Epatocentro Ticino Paediatric Liver GI and Nutrition CentreMowat LabsKing’s College Hospital Institute of Liver Studies Mowat LabsKing’s College Hospital

Autoimmune hepatitis is a rare chronic inflammatory liver disease,affecting all ages,characterised by elevated transaminase and immunoglobulin G levels,positive autoantibodies,interface hepatitis at liver histology and good response to immunosuppressive treatment. If untreated,it has a poor prognosis. The aim of this review is to summarize the evidence for standard treatment and to provide a systematic review on alternative treatments for adults and children. Standard treatment is based on steroids and azathioprine,and leads to disease remission in 80%-90% of patients. Alternative first line treatment has been attempted with budesonide or cyclosporine,but their superiority compared to standard treatment remains to be demonstrated. Second-line treatments are needed for patients not responding or intolerant to standard treatment. No randomized controlled trials have been performed for second-line options. Mycophenolate mofetil is the most widely used second-line drug,and has good efficacy particularly for patients intolerant to azathioprine,but has the major disadvantage of being teratogenic. Only few and heterogeneous data on cyclosporine,tacrolimus,everolimus and sirolimus are available. More recently,experience with the anti-tumour necrosis factoralpha infliximab and the anti-CD20 rituximab has been published,with ambivalent results; these agents may have severe side-effects and their use should be restricted to specialized centres. Clinical trials with new therapeutic options are ongoing.

关键词： Autoimmune hepatitis Standard treatment Second-line treatment Adults Children