检索结果-南通市图书馆

Open Journal of Orthopedics 2022年第11期12卷 442-449页

作者： diallo mamadou Moustapha Lamah Leopold Barry Alhassane Camara Nouhou Mangue diallo alpha mamadou fellah Department of Orthopedic Traumatological Surgery of the Donka National Hospital Conakry Guinea

Carpo-metacarpal dislocations are rare hand injuries. They are misdiagnosed due to their non-specific clinical signs. The authors report on their experience in the management of carpometacarpal dislocations in a specialized hand surgery center. Our study included patients received and treated in the department for a carpometacarpal dislocation. Dislocation fractures of Bennett and Rolando were excluded. The postoperative functional evaluation took place after 18 months by the DASH score. Twelve patients participated: one case of neuro-algodystrophy and one pin infection. The mean DASH functional outcome score was 1.10 at 18 months. Since carpometacarpal dislocations are rare and easily misdiagnosed, the surgeon should assume the possibility of them in patients with high-energy trauma, and imaging studies should be carefully evaluated. Pinning is an effective treatment option that provides good long-term functional results.

关键词： Dislocation Fracture Carpo-Metacarpal Joints

Diabetes Screening and Cardiovascular Risk in Tuberculosis Patients in Conakry and Surrounding Towns

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Endocrine and Metabolic Diseases 2024年第1期14卷 7-13页

作者： mamadou Chérif diallo mamadou Dian Mamoudou diallo Mody Abdoulaye Barry Kadija Dieng alpha mamadou diallo mamadou Mansour diallo Oumou diallo Amadou Kaké Gamal Abdel Nasser University of Conakry Conakry Guinea Endocrinology-Diabetology Department of Donka University Hospital Conakry Guinea Foundation for The Fight against Diabetes and Non-Communicable Diseases Conakry Guinea

Objective: To determine the prevalence of diabetes and the level of cardiovascular risk in tuberculosis patients treated in Conakry and surrounding towns. Method: This was a cross-sectional study carried out at tuberculosis treatment centers in Conakry and surrounding towns (Coyah and Dubréka) on World TB Day, November 14, 2022, among 350 tuberculosis patients. We determined the proportion of TB patients with diabetes and high hyperglycemia. We determined the Chi-square to identify the factors associated with the occurrence of diabetes in tuberculosis patients, and a significance threshold with p Results: The average age of participants was 33.5 ± 14.5 years, and they were predominantly male (59.7%). The majority of participants lived in Conakry (96.3%). 5.7% were known diabetics and 4.6% were known hypertensives. We found a prevalence of diabetes of 9.4%. Among diabetics, 39% were diabetes discoveries. 30% were hypertensive or had high blood pressure. Of these hypertensive patients, 26.4% were unrecognized hypertensives. Age and hypertension were statistically significantly associated with the onset of diabetes in tuberculosis patients. Medium, high and very high levels of cardiovascular risk were present in 23.4%, 8.9% and 3.4% respectively. Conclusion: Diabetes is common in tuberculosis patients. Cardiovascular risk factors, notably hypertension and cardiovascular risk level, are frequently associated with tuberculosis. Tuberculosis patients with cardiovascular risk factors should be screened for diabetes.

关键词： Screening Diabetes Tuberculosis Cardiovascular Risk Conakry

Frequency and Risk Factors of Neonatal Macrosomia at Labe Regional Hospital in Guinea

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Endocrine and Metabolic Diseases 2024年第2期14卷 26-32页

作者： mamadou Dian Mamoudou diallo mamadou Mansour diallo mamadou Chérif diallo alpha mamadou diallo Kadija Dieng Mody Abdoulaye Barry mamadou alpha diallo Kadidiatou Bah Abdou Mazid diallo El’hadj Zainoul Bah mamadou Malal Bori diallo mamadou Sanou Sylla Amadou Kaké Diabetes Unit Labe Regional Hospital Labe Guinea Faculty of Health Sciences and Technology University of Conakry Conakry Guinea Department of Diabetes and Endocrinology Donka Hospital and University Center Conakry Guinea Neonatology Unit Labe Regional Hospital Labe Guinea

Macrosomia is defined as a term birth weight greater than or equal to 4000 grams, or greater than the 90 percentile of intrauterine growth curves. Excessive weight has harmful consequences for the newborn and is a major health concern. Objectives: To determine the frequency of neonatal macrosomia, describe risk factors and neonatal and maternal complications. Materials and methods: This was a cross-sectional study carried out between January and December 2022, involving newborns whose birth weight was greater than or equal to 4000 grams admitted to the neonatology unit of the Labe regional hospital. Results: 591 deliveries were recorded, 15 of which were macrosomic, representing a frequency of 2.54%. The average age of the women was 30.26 years. History of fetal macrosomia and diabetes was 93.33 and 71.43% respectively. The mean gestational age was 38.71 ± 0.75 SA, the mean antenatal consultation was 3 ± 0.8 and the mode of delivery was caesarean section (66.67%). Third-trimester ultrasound was performed in 53.33% of cases. Macrosomic newborns were male in 80% of cases. Neonatal complications were asphyxia (60%), hypoglycemia (20%) and hypocalcemia (13.33%). Factors associated with neonatal macrosomia were diabetes (P < 0.001), history of macrosomia (P Conclusion: this study shows that the frequency of neonatal macrosomia is 2.54% with high neonatal morbidity among newborns hospitalized in the neonatology unit of the Labé regional hospital. Screening for macrosomia risk factors during pregnancy is essential to prevent perinatal complications.

关键词： Frequency Macrosomia Labe

Hypothyroidism in Conakry: Epidemiological, Clinical and Therapeutic Aspects

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Internal Medicine 2022年第1期12卷 38-45页

作者： Amadou Kaké Djibril Sylla alpha mamadou diallo mamadou Mansour diallo diallo Kourouma Amadou Diango mamadou alpha diallo Elhadj Zainoul Bah mamadou Cherif diallo Kadija Dieng Mody Abdoulaye Barry Naby Moussa Baldé Department of Endocrinology and Metabolic Diseases Donka University Hospital Conakry Guinea Department of Internal Medicine Donka University Hospital Conakry Guinea

Hypothyroidism is a frequent endocrine disorder that can occur at any age and predominantly affects women. The etiologies are diverse and may vary according to the geographical and socio-demographic context. The objective of our work was to describe the epidemiological, clinical and therapeutic characteristics of hypothyroidism in Conakry, Guinea. Materials and Method: This was a descriptive study with prospective data collection, over the period from December 2016 to May 2021. It focused on patients seen at the endocrinology consultation of Conakry University Hospital. Epidemiological, clinical, etiological, therapeutic, and evolutionary variables of patients diagnosed or followed-up for hypothyroidism were collected and analyzed. The diagnosis of hypothyroidism was defined by elevated TSH and/or decreased FT4/FT3. Results: Out of a total of 290 patients who consulted for thyroid pathology, hypothyroidism concerned 49 patients, i.e. , a frequency of 14%. Women were the most affected with a sex ratio of 0.13. The mean age of patients was 48.65 ± 19.93 years with extremes of 2 years and 80 years. Hypo-metabolic syndrome was the main clinical sign and was manifested mainly by constipation found in 48.89% of cases. TSH was elevated in all cases with a mean level of 24.56 ± 14.17 mIU/ml. Hypertension was the most frequently associated pathology (57%). Three etiological groups of hypothyroidisms were found. These were thyroidectomy in 42.85% of cases, thyroiditis in 34.69% of cases and post synthetic antithyroid hypothyroidism. All patients were treated with L-thyroxin, with a favorable clinical course. Follow-up was regular in 16 patients (32.65%). Conclusion: Hypothyroidism is common in this population, and primarily affects women. Thyroid surgery was the main cause of hypothyroidism in this work.

关键词： Hypothyroidism Goiter Hashimoto Guinea

Role of Nrf2 in chronic liver disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第36期20卷 13079-13087页

作者： Wei Tang Yong-Fang Jiang Murugavel Ponnusamy mamadou diallo Liver Diseases Research Center The Second Xiangya Hospital Central South University Department of Medicine Rhode Island Hospital and Alpert Medical School of Brown University Providence RI 02903 United States Department of Immunology and Infectious Diseases Harvard School of Public Health Harvard UniversityBoston MA 02115-6018 United States

Nuclear erythroid 2-related factor 2(Nrf2) is a central regulator of antioxidative response elements-mediated gene expression. It has a significant role in adaptive responses to oxidative stress by interacting with the antioxidant response element, which induces the expression of a variety of downstream targets aimed at cytoprotection. Previous studies suggested oxidative stress and associated damage could represent a common link between different forms of diseases. Oxidative stress has been implicated in various liver diseases, including viral hepatitis, nonalcoholic fatty liver disease/steatohepatitis, alcoholic liver disease and drug-induced liver injury. Nrf2 activation is initiated by oxidative or electrophilic stress, and aids in the detoxification and elimination of potentially harmful exogenous chemicals and their metabolites. The expression of Nrf2 has been observed throughout human tissue, with high expression in detoxification organs, especially the liver. Thus, Nrf2 may serve as a major regulator of several cellular defense associated pathways by which hepatic cells combat oxidative stress. We review the relevant literature concerning the crucial role of Nrf2 and its signaling pathways against oxidative stress to protect hepatic cell from oxidative damage during development of common chronic liver diseases. We also review the use of Nrf2 as a therapeutic target to prevent and treat liver diseases.

关键词： Nuclear erythroid 2-related factor 2 Chronic liver disease Oxidative stress Reactive oxygen species Hepatic injury Hepatic protection

Practice of Glycemic Self-Monitoring in Diabetic Patients Followed at the Endocrinology Department of Donka University Hospital in Guinea

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Endocrine and Metabolic Diseases 2024年第2期14卷 33-38页

作者： mamadou Dian Mamoudou diallo mamadou Mansour diallo mamadou Chérif diallo alpha mamadou diallo Kadija Dieng Abdoul Mazid diallo Mody Abdoulaye Barry Kadidiatou Bah El’Hadj Zainoul Bah mamadou alpha diallo Ibrahima Condé Ousmane Kourouma Amadou Kaké Diabetology Unit Labe Regional Hospital Labé Guinea Faculty of Health Sciences and Techniques Gamal Abdel Nasser University of Conakry Conakry Guinea Endocrinology and Diabetology Department of Donka University Hospital Conakry Guinea Pediatrics Department of Donka University Hospital Conakry Guinea

Diabetes is a chronic pathology whose evolution is marked by micro and macroangiopathic complications. Optimal management can prevent the onset of complications and improve patients’ quality of life. Objectives: To determine the frequency of self-monitoring of blood glucose and to describe the errors found during self-monitoring in diabetic patients followed at the Endocrinology Department of Donka University Hospital in Guinea. Materials and methods: Descriptive cross-sectional study carried out between August and September 2020 involving diabetic patients followed up at the Endocrinology and Diabetology Department of the Donka National Hospital, CHU Conakry. Results: A total of 301 patients were enrolled, with an average age of 44.24 ± 21.01 years. 64.12% were female. Type 2 diabetes predominated in 64% of cases. The mean duration of diabetes was 6.14 ± 4.67 years, and 75.08% of patients lived in urban areas. Patients were on insulin in 36.21% of cases, insulin and biguanides (26.25%), hypoglycemic sulfonamide and biguanides (19.27%) and biguanides in 18.27% of cases. The frequency of self-monitoring of blood glucose was 43%, and 38% of patients made errors, notably reusing lancets (60%), not checking the expiration date (55.65%) and not washing their hands (48%). Conclusion: This study shows that self-monitoring of blood glucose is not performed by the majority of patients. Numerous errors were identified during blood glucose testing. Continued therapeutic education on the use of blood glucose meters will help empower patients and improve their quality of life.

关键词： Self-Monitoring of Blood Glucose Diabetes Conakry University Hospital

Diagnostic Itinerary of Patients Monitored for Thyroid Disease at the Conakry University Hospital in 2022

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Endocrine and Metabolic Diseases 2024年第9期14卷 165-177页

作者： Elhadj Zainoul Bah alpha mamadou diallo Kadidiatou Bah mamadou Dian Mamoudou diallo Abdoul Mazid diallo mamadou alpha diallo mamadou Chérif diallo mamadou Mansour diallo Mody Abdoulaye Barry Oumar Telly Sow Kadija Dieng Amadou Kaké Amadou Bah Faculty of Health Sciences and Technology Gamal Abdel Nasser University of Conakry Conakry Republic of Guinea Department of Endocrinology Metabolic Diseases and Nutrition Donka University Hospital Conakry Republic of Guinea Ministry of Health and Public Hygiene Conakry Republic of Guinea Regional Health Inspection of Lab Conakry Republic of Guinea

Introduction: Thyroid pathologies are either the cause or a consequence of certain pathologies with which they interact, manifesting themselves through a polymorphic and non-specific clinic. They affect different devices and/or systems, making the clinical picture more complex or even a delay in diagnosis and treatment. These latter aspects, being then multidimensional, could be preceded by a very specific patient itinerary for the diagnosis and management of cases of thyroid gland pathologies. Methods: This was a descriptive cross-sectional study whose data were collected from May 1 to October 30, 2022. It focused on patients followed for thyroid diseases at the Conakry University Hospital. The objectives were to describe the patient’s journey before their diagnosis of thyroid disease. Results: The subjects were 86.1% women with a mean age of 43.7 ± 28 years. Of the total, 67.85% had a comorbidity including diabetes and/or hypertension/heart disease. They are followed for goiters/simple nodules (22.78%), hypothyroidism (16.46%) and hyperthyroidism (60.76%). They spend at least 9 months before resorting to a healthcare facility. The general medicine services of the Conakry University Hospital are the first recourse (51.9%) of these subjects. They consult 2 to 4 times before the diagnosis is suggested. Hyperthyroidism, hypothyroidism and goiters/simple nodules spend 5.4;6.4 and 13.7 months respectively before the diagnosis is made. 31.6% were hospitalized and treated mainly for malaria (19.0%), hypertension (13.1%), salmonellosis (13.1%) and diabetes (8.3%). A third of patients used traditional therapy before being in contact with the endocrinology department by referral (73.4%). Conclusion: This study made it possible to show a pre-diagnostic pathway which has a particular character concerning patients followed for thyroid pathologies in Guinea.

关键词： Itinerary Diagnosis Thyroid Conakry

Epidemiological, Clinical and Biological Characteristics of Patients with Chronic Hepatitis B Infection Followed-Up at the University Hospital of Conakry, Guinea

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Gastroenterology 2020年第10期10卷 256-265页

作者： Djenabou diallo Kadiatou diallo alpha mamadou diallo mamadou Mansour diallo Thierno Amadou Wann Amadou Diouldé Doumbouya Ousmane Sow Youssouf Baldé alpha Amadou Sank Dillo Department of Internal Medicine University Hospital of Donka Conakry Guinea Department of Endocrinology Diabetes and Metabolic Diseases University Hospital of Donka Conakry Guinea

Introduction: Very little information is available in Guinea on chronic hepatitis B infections. The objective of this study was to describe the epidemiological, clinical and biological features of patients who are chronic carriers of the hepatitis B virus. Patients and Methods: This is a retrospective study carried out from January 2017 to May 2020, based on the medical records of patients seen via consultation or hospitalized with a record of positive HBs antigen for more than 6 months. Clinical and paraclinical data were collected and analyzed. Results: Seven hundred and sixteen patients with a mean age of 35.6 ± 12.2 (sex ratio 2.05), were included. The HBs antigen was discovered incidentally in 36% of cases (n = 258). A history of dental care and surgical procedures was found in 46.3% (n = 290) and 21.1% (n = 138) of cases, respectively. The median value of ALAT enzymes was 34 (21 - 47) IU/L. HBeAg was positive in 20.8% (n = 55/265) of cases. The median B viral load was 458.5 (87 - 3827) IU/ml and 29% (n = 94) of patients had a viral load over 2000 IU/ml. Anti-HCV antibody was present in 10.4 % of cases (n = 39/374). HIV serology was positive in 2.7% (n = 8/298). A total of 19.4% (n = 139) of the patients had cirrhosis and 4.5% (n = 32) had hepatocellular carcinoma. Conclusion:

Photoassisted Ozonation of Red Cationic X-GRL Dyeing Wastewater Treatment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photoassisted Ozonation of Red Cationic X-GRL Dyeing Wastewa...

作者： diallo mamadou DA? 浙江大学

学位级别：硕士

学位论文的主要内容及创新点：印染(阳离子红X-GRL)废水的特点是高的色度，高pH值和有机污染物质集中，从而造成景观质量变差。世界印染工业的高速发展带动了对印染废水处理的研究。然而，众所周知，印染(阳离子红X-GRL)废水... 详细信息

学位论文的主要内容及创新点：印染(阳离子红X-GRL)废水的特点是高的色度，高pH值和有机污染物质集中，从而造成景观质量变差。世界印染工业的高速发展带动了对印染废水处理的研究。然而，众所周知，印染(阳离子红X-GRL)废水很难被传统的处理方式(比如物化和生化方法)处理。臭氧氧化方法将会有助于在染工业方面保护环境和重复使用水。应用臭氧处理，虽然有很多优点，但是对许多难降解有机物却很难做到完全去除!尽管鼓励将O和UV结合起来。在这篇论文中，我们研究了这个高级氧化技术，以期达到处理的最优化，。研究了反应条件的影响：温度，时间，pH，色度，CODcr，BOD和反应机理被调查。实验的结果显示，作为一种深度处理的方式，臭氧对废水的氧化、除色以及循环使用都是非常有效的。将UV和臭氧结合起来，结果表明是很有效的。研究了臭氧+UV对印染(阳离子红X-GRL)废水的氧化处理情况。在相同的实验条件下，将这些系统的氧化产物和产量与臭氧氧化的产物和产量进行比较。臭氧氧化使得COD降解速度提高(在pH3下)。臭氧+UV体系对COD和BOD的降解都有很大的提高，这说明它是最好的氧化方式。无论是什么废水，氧化体系(脱色)与臭氧氧化本身比较。不同的动力学叁数也决定到对於被应用的氧化系统的废水反应度的量。 C，O=30mg/L，kobs=9743,66exp(-32610／RT)[HO]0.023(S) C，O=50mg／L，kobs=5024,53exp(-32610／RT)[HO]0.023(S) C，O=80mg／L kobs=3687.01exp(-32610／RT)[HO)0.023(S)

关键词：染料臭氧氧化废水处理技术研究阳离子红X-GRL 脱色反应动力学和反应机制涂颜色

Prevalence of Diabetes and Hypertension on World Diabetes Day 2022 in Guinea

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Open Journal of Endocrine and Metabolic Diseases 2024年第1期14卷 1-6页

作者： mamadou Dian Mamoudou diallo mamadou Mansour diallo mamadou Chérif diallo mamadou alpha diallo alpha mamadou diallo Mody Abdoulaye Barry Kadija Dieng Abdoul Mazid diallo El’Hadj Zainoul Bah Kadidiatou Bah Amatoulaye diallo Amadou Kaké Naby Moussa Baldé Oumou Baldé Unité de Diabétologie H&#244pital régional de Labé Labe Guinea Université de Conakry Conakry Guinea Service de Diabétologie CHU Donka Conakry Guinea Fondation de Lutte Contre le diabète et MNT Conakry Guinea

Introduction: Diabetes mellitus and hypertension are chronic diseases that are on the rise and pose a major public health problem among the priorities of healthcare systems. Objectives: Determine the prevalence of diabetes and hypertension and describe the sociodemographic characteristics of those screened. Materials and Methods: This was a cross-sectional study organized during a diabetes and hypertension screening campaign that took place in Conakry and five (05) inland regions on November 14, 2022. Results: 2050 people were screened, of whom 33.12% were housewives, the average age was 44.78 ± 16.23 years, and 55.27% were women. The screening sites were the city of Conakry 741 (36.15%), the Labé region 424 (20.68%), the N’Zérékoré region 298 (14.54%), the Faranah region 241 (11.75%), the Mamou region 210 (10.24%) and the Boké region 136 (6.63%). The prevalence of diabetes and hypertension were respectively 12.5% and 43.38% for the Boké region;6.19% and 16.19% for the Mamou region;3.02% and 21.81% for the N’Zérékoré region;31.95% and 13.69% for the Faranah region;9.67% and 20.28% for the Labé region;2.83% and 20.28% for the city of Conakry. Conclusion: Despite the limitations of the study duration, our series highlighted the high prevalence of diabetes and hypertension among people screened on World Diabetes Day 2022. Raising public awareness of a healthy lifestyle is essential for the prevention and control of diabetes and hypertension.

关键词： Prevalence Diabetes Hypertension