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表现为苔藓样损害的拟诊IgG4-RD 1例

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口腔医学研究 2024年第6期40卷 561-563页

作者：张天玉陆轩江潞口颌系统重建与再生全国重点实验室国家口腔疾病临床医学研究中心、陕西省口腔疾病临床医学研究中心、空军军医大学第三附属医院儿童口腔科陕西西安710032 大连市口腔医院修复科辽宁大连116021 口腔疾病研究国家重点实验室、国家口腔疾病临床医学研究中心、四川大学华西口腔医院黏膜病科四川成都610041

免疫球蛋白G4相关疾病(immunoglobulin G4-related disease,IgG4-RD)是一种全身性多器官纤维炎性疾病,罕见累及口腔黏膜的病例报道。本文报道1例临床表现为苔藓样损害的拟诊IgG4-RD的诊治,该报道丰富了IgG4-RD口腔黏膜病损表现,同时提... 详细信息

免疫球蛋白G4相关疾病(immunoglobulin G4-related disease,IgG4-RD)是一种全身性多器官纤维炎性疾病,罕见累及口腔黏膜的病例报道。本文报道1例临床表现为苔藓样损害的拟诊IgG4-RD的诊治,该报道丰富了IgG4-RD口腔黏膜病损表现,同时提示临床实践中鉴别诊断的重要性。

关键词：免疫球蛋白G4相关性疾病自身免疫性疾病苔藓样损害

海南岛周邻新生代沉积盆地构造与差异性演化特征

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地质学报 2024年第1期98卷 16-30页

作者：吴时国鲁向阳李刚龙根元海南省海底资源与探测技术重点实验室中国科学院深海科学与工程研究所海南三亚572000 南方海洋科学与工程广东省实验室(珠海) 广东珠海519000 东北石油大学三亚海洋油气研究院海南三亚572025 海南省地质局海南省海洋地质调查研究院海南海口570000

海南岛周邻发育有4个重要的新生代沉积盆地,即莺歌海盆地、北部湾盆地、琼东南盆地和珠江口盆地珠三凹陷。根据最新的地球物理数据,重新厘定这些盆地的构造与沉积演化及其与海南岛陆上构造的关联。这些盆地发育NE和NW向断裂构造,但存在... 详细信息

海南岛周邻发育有4个重要的新生代沉积盆地,即莺歌海盆地、北部湾盆地、琼东南盆地和珠江口盆地珠三凹陷。根据最新的地球物理数据,重新厘定这些盆地的构造与沉积演化及其与海南岛陆上构造的关联。这些盆地发育NE和NW向断裂构造,但存在极大差异性。前者受红河哀牢山断裂构造影响,表现为张扭性的拉分盆地。而后三个盆地则总体表现为裂陷盆地,夹于江绍-博白断裂与丽水-南澳断裂南段之间。伸展始于古新世,具有四次裂陷作用,并发育NW向走滑伸展断层。晚期岩浆对沉积盆地具有一定改造作用,表现岩浆喷发、热流值高。我们厘定了这些NE向断裂在海南岛延伸,滨海断裂可能延至海南岛东南缘,并表现出明显的地震活动性,推断海南岛新生代构造演化与南海北部陆缘演化具有一致性。

关键词：构造演化拉分盆地裂陷盆地地层层序南海

Molecular Cloning of sodB Gene from Vibrio alginolyticus HY9901 and Its Bioinformatics Analysis

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Asian Agricultural Research 2024年第7期16卷 42-47页

作者： Shuai YANG Yingying JIANG Haiyun FENG Weijie ZHANG Na WANG Xiaonan lu Huanying PANG Fisheries College Guangdong Ocean UniversityZhanjiang 524025China Guangdong Provincial Key Laboratory of Aquatic Animal disease Control and Healthy Culture&Key Laboratory of Control for diseases of Aquatic Economic Animals of Guangdong Higher Education Institutes Zhanjiang 524025China Chinese Academy of Inspection and Quarantine Beijing100176China Department of Food Science and Agricultural Chemistry Faculty of Agricultural and Environmental SciencesMcGill UniversitySainte-Anne-de-Bellevue H9X 3V9Canada

Vibrio alginolyticus is a zoonotic bacterium.A pair of specific primers was designed using the sodB gene sequence of Vibrio alginolyticus HY9901 in order to amplify the full length of the gene by *** results indicated that the total length of the sodB gene was 585 bp and that it could encode 194 amino *** predicted amino acid sequence derivation indicated that the molecular weight of the protein was approximately 21.56 kDa,with an isoelectric point of *** prediction of the N-terminal signal peptide structure of the protein,no significant signal peptide cleavage site was observed,indicating that the protein lacked both a signal peptide and a transmembrane *** amino acid sequence contained an N-glycosylation site,a casein kinase II phosphorylation site,a microsomal C-terminal target signal site,and a manganese and iron superoxide dismutase signal *** probability of intracytoplasmic localization of the SodB protein was 56.5%,which was analyzed according to the subcellular localization of the *** amino acid sequence of the sodB gene of *** exhibited 98%-100%homology to other Vibrio species,clustering into the same subfamily with ***,indicating a relatively close relationship between *** the prediction of protein structure,the proportions ofα-helix,random coil,β-sheet,and extended strand were 48.45%,30.41%,5.67%,and 15.46%,*** similarity to template 1dt0.1.A reached 71.58%.A PTM site analysis revealed the presence of phosphorylation,glycosylation,ubiquitination,sumoylation,acetylation,and methylation modification sites,as well as the absence of lactylation modification sites.

关键词： Vibrio alginolyticus Gene cloning sodB gene Bioinformatics analysis

Advances in Research of Collection and Detection Methods of Microplastics in Environment

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Asian Agricultural Research 2024年第9期16卷 23-27,31页

作者： Yunshuang FU Zhen ZHAO Peng WAN Guoyan WEN Haibo FAN Cuizhi LI Zhiyong lu National Center of Technology Innovation for Dairy Hohhot 010080China Inner Mongolia Yili Industrial Group Co. Ltd.Hohhot 010010China

As a new type of environmental pollutants,microplastics have gradually attracted people s attention.A large number of plastics discharged into the environment by human beings are constantly aging and breaking,and finally become *** can adsorb pollutants in the environment,and their components have certain toxicity,which can cause different degrees of harm to *** to the structural characteristics of microplastic particles,such as small particle size,large specific surface area,and their distribution in different environmental media,it is very difficult to accurately detect *** collection and detection methods are the key to the study of environmental behavior of *** this study,the collection and detection methods of microplastics in the environment were reviewed,and the development direction of microplastics detection technology in the future was *** study has a certain reference value for the related research and the prevention and treatment of micro-plastic pollution.

关键词： Microplastics Collection method Detection method

莲固体废弃物中多酚类物质的喷雾干燥微胶囊化研究

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食品工业科技 2018年第10期39卷 222-227页

作者：颜征张海晖李亚群段玉清张迪陆玉洪孙冀平江苏大学食品与生物工程学院江苏镇江212013 江苏怡味莲朗伯食品有限公司江苏宝应225800

本文为保护莲固体废弃物多酚类物质活性成分免受破坏,增强多酚稳定性。以莲固体废弃物多酚类物质微胶囊包埋率为指标,通过单因素、正交和响应面实验,优选多酚类物质喷雾干燥微胶囊化的工艺参数。结果表明,多酚微胶囊化的最佳壁材配方为... 详细信息

本文为保护莲固体废弃物多酚类物质活性成分免受破坏,增强多酚稳定性。以莲固体废弃物多酚类物质微胶囊包埋率为指标,通过单因素、正交和响应面实验,优选多酚类物质喷雾干燥微胶囊化的工艺参数。结果表明,多酚微胶囊化的最佳壁材配方为阿拉伯胶∶β-环状糊精为3∶1,芯壁比为1∶5,单甘酯添加量为0.10%。多酚类物质喷雾干燥微胶囊化最优条件为:进料固形物含量16%,进料速度280 m L/h,进风温度为185℃,出风温度80℃。在此条件下,得到莲固体废弃物多酚微胶囊包埋率为94.12%+0.37%,微胶囊包埋效果较优,为多酚类物质的喷雾干燥微胶囊化提供了理论依据。

关键词：莲固体废弃物多酚喷雾干燥微胶囊化

The involvement of Slc7a11/xCT related iron accumulation on acupuncture intervention in 6-OHDA-induced Parkinson rat

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Clinical Traditional Medicine and Pharmacology 2024年第4期5卷 34-43页

作者： Lihong Li Wei Jin Jun lu Zitong Xu Zhaoshun Lv Jianquan Yin Wenjie Cong Acupuncture Department The Second Affiliated Hospital of Zhejiang Chinese Medical University(Xinhua Hospital of Zhejiang Province)Hangzhou 310005ZhejiangChina The First School of Clinical Medicine Zhejiang Chinese Medical UniversityHangzhou 310053ZhejiangChina Urological Department Zitong Hospital of Traditional Chinese MedicineMianyang 622150SichuanChina The Second School of Clinical Medicine Zhejiang Chinese Medical UniversityHangzhou 310053ZhejiangChina Acupuncture Department Zhejiang Provincial People’s HospitalHangzhou 310004ZhejiangChina Acupuncture and Physiotherapy Department The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325015ZhejiangChina

Background:Acupuncture plays a critical role for the treatment of patients with Parkinson’s disease(PD),which is characterized by ferroptosis of dopaminergic *** has been found that acupuncture can reduce iron ***,the mechanism of acupuncture therapy against PD by inhibiting ferroptosis remains ***:To investigate the potential mechanism of acupuncture on alleviating ferroptosis in 6-OHDA-induced PD ***:Male Sprague-Dawley rats were randomly divided into sham group,acupuncture group,and PD model group,with the PD model induced by *** motor function of the rats was tested by the rotation test and suspension test,*** and iron staining were performed to analyze nerve damage,and the effect of acupuncture on the accumulation of iron in the substantia nigra(SN).RNA-seq analysis in the SN of rats were performed to discover ferroptosis-related *** expressed genes(DEGs)resulted from the acupuncture treatment were identified and were used for Gene Ontology(GO)function,Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analyses.A protein–protein interaction(PPI)network was constructed,and alternative splicing(AS)analysis of the transcriptome was *** blot was used to detect the protein level change of Slc7a11/***:Rotation test and suspension test indicated a positive effect of acupuncture on body weight gain and limb ***’s iron staining and ELISA test detected 6-OHDA induced iron accumulation in the SN and nerve damage,which was mitigated by acupuncture *** treatment brought about the differential expression of a total of 1088 genes in the SN of *** and KEGG enrichment revealed that such DEGs were mainly associated with several key biological process(BP),cellular component(CC)and molecular function(MF)*** terms included collagen fibril organization,extracellular matrix organization,collagen trimer,extracel

关键词： Parkinson’s disease RNA-seq Slc7a11/xCT Acupuncture

脉冲激光处理等离子体冲击-空化原理的间接验证和理论应用

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Transactions of Nonferrous Metals Society of China 2024年第2期34卷 576-581页

作者：卢国鑫罗学昆王强刘纪德季忠陆峰孙晓峰山东大学材料科学与工程学院材料液固结构演变与加工教育部重点实验室济南250061 中国航发北京航空材料研究院航空材料先进腐蚀与防护航空科技重点实验室北京100095 中国科学院金属研究所师昌绪先进材料创新中心沈阳110016

提出等离子体冲击-空化双物理效应耦合强化原理,在液体约束脉冲激光冲击中空化效应存在的合理性有待证实。选择XRD测试方法和较易获得衍射峰的304不锈钢,定量检测和表征单脉冲激光作用区域的残余应力分布。试验结果与文献分析表明,激光... 详细信息

提出等离子体冲击-空化双物理效应耦合强化原理,在液体约束脉冲激光冲击中空化效应存在的合理性有待证实。选择XRD测试方法和较易获得衍射峰的304不锈钢,定量检测和表征单脉冲激光作用区域的残余应力分布。试验结果与文献分析表明,激光冲击强化的不同工艺条件导致等离子体冲击与空化两种应力效应的强度匹配不同,无涂层飞秒激光冲击应力效应的主要来源是空化效应。激光脉冲宽度以及吸收层和约束层等工艺参量的实际作用影响或决定脉冲激光表面处理的材料改性原理。

关键词：激光材料加工等离子体冲击空化表面强化

Minocycline in the eradication of Helicobacter pylori infection: A systematic review and meta-analysis

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World Journal of Gastroenterology 2024年第17期30卷 2354-2368页

作者： Kai Zhou Cai-Ling Li Hua Zhang Bao-Jun Suo Yu-Xin Zhang Xin-lu Ren Yu-Xin Wang Chang-Min Mi Ling-Ling Ma Li-Ya Zhou Xue-Li Tian Zhi-Qiang Song Department of Gastroenterology Peking University Third HospitalBeijing 100191China

BACKGROUND difficulty in obtaining tetracycline,increased adverse reactions,and relatively complicated medication methods have limited the clinical application of the classic bismuth quadruple ***,the search for new alternative drugs has become one of the research *** recent years,minocycline,as a semisynthetic tetracycline,has demonstrated good potential for eradicating Helicobacter pylori(***)infection,but the systematic evaluation of its role remains *** To explore the efficacy,safety,and compliance of minocycline in eradicating *** *** We comprehensively retrieved the electronic databases of PubMed,Embase,Web of Science,China National Knowledge Infrastructure,SinoMed,and Wanfang database as of October 30,2023,and finally included 22 research reports on *** eradication with minocycline-containing regimens as per the inclusion and exclusion *** eradication rates of *** were calculated using a fixed or a random effect model,and the heterogeneity and publication bias of the studies were *** The single-arm meta-analysis revealed that the minocycline-containing regimens achieved good overall *** eradication rates,reaching 82.3%[95%confidence interval(CI):79.7%-85.1%]in the intention-to-treat analysis and 90.0%(95%CI:87.7%-92.4%)in the per-protocol *** overall safety and compliance of the minocycline-containing regimens were good,demonstrating an overall incidence of adverse reactions of 36.5%(95%CI:31.5%-42.2%).Further by traditional meta-analysis,the results showed that the minocycline-containing regimens were not statistically different from other commonly used eradication regimens in eradication rate and incidence of adverse *** of the adverse reactions were mild to moderate and well-tolerated,and dizziness was relatively prominent in the minocycline-containing regimens(16%).CONCluSION The minocycline-containing regimens demonstrated good efficacy,safety,and

关键词： Helicobacter pylori Minocycline Eradication Safety Resistance

锂离子电池正极材料原位漫反射光谱电化学研究

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电化学（中英文） 2024年第6期30卷 24-31页

作者：陈露露李浩冉刘维祎王伟生命分析化学国家重点实验室南京大学化学化工学院江苏南京210023

发展原位电化学光谱方法对深入研究电化学反应机理,并最终提高电池性能有着重要价值。建立在这一认识之上,能够应用于电池体系的原位光谱电化学表征技术被认为是表征电池电极材料性能的有效方法。但是受限于电池严格密封的不透明外壳和... 详细信息

发展原位电化学光谱方法对深入研究电化学反应机理,并最终提高电池性能有着重要价值。建立在这一认识之上,能够应用于电池体系的原位光谱电化学表征技术被认为是表征电池电极材料性能的有效方法。但是受限于电池严格密封的不透明外壳和当前商用电池体系严格隔绝水氧的客观要求,开发更贴近真实电池工作条件的原位光谱电化学表征技术仍有较大需求。基于此,本文设计了一种基于传统纽扣电池架构的原位电化学池,该装置通过特殊设计实现了在尽可能模拟电池工作环境的前提下拥有透明的上盖,从而使发生电化学反应的同时进行光学检测成为可能。利用这一电化学池,本文以锂离子电池中常用的正极材料LiFePO_(4)(LFP)、NCM811和LiCoO_(2)(LCO)为例,对其电化学反应过程中的漫反射光谱进行了采集和分析。相关数据定量地揭示了不同种类电极材料在一般反射光路架构下对不同波长可见光的响应关系,并能够直接用于对单色光检测场景下的波长优化提供指导和依据。更进一步,本文还对不同材料在充放电过程中的光谱特征进行了定量分析,揭示了其光谱特征同材料内在能级状态间的相关性。综上,本文提出了一种基于漫反射光谱的原位光谱电化学表征方法,作为对光谱电化学应用于电池体系的有效补充,本方法能够为评估电极材料性能提供一种全新且简单直接的途径,并最终助力电池性能的提升。

关键词：锂离子电池漫反射光谱电化学原位正极材料