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Update on endoscopic ultrasound-guided liver biopsy

World Journal of Gastroenterology 2022年第28期28卷 3586-3594页

作者： Shiva rangwani devarshi r ardeshna Khalid Mumtaz Sean G Kelly Samuel Y Han Somashekar G Krishna Division of Gastroenterology Hepatologyand NutritionDepartment of Internal MedicineOhio State University Wexner Medical CenterColumbusOH 43210United States

Endoscopic ultrasound guided liver biopsy(EUS-LB)has emerged as a minimally-invasive alternative to the traditional(percutaneous or transjugular)liver biopsy techniques for the diagnosis of liver parenchymal ***,EUS-LB combines the advantages of percutaneous and transjugular liver biopsy in addressing focused sampling in addition to measuring portal ***,EUS-LB facilitates access to both the lobes of the liver which is not considered with the traditional percutaneous liver *** studies have compared EUS-LB with conventional liver biopsy and reported comparable diagnostic yield,increased acquisition of complete portal tracts,and longer specimen length as compared to the traditional ***-LB is associated with lesser post-procedural pain and shorter recovery time,while providing lower risk of complications when compared to traditional liver *** in needle types,needle sizes and suction techniques have aimed at further optimizing the EUS-LB *** review article updates current literature with focus on the variations in the technique and equipment used for EUS-LB,and compares EUS-LB with traditional methods of liver biopsy.

关键词： Endoscopic ultrasound guided liver biopsy Liver biopsy Percutaneous liver biopsy Transjugular liver biopsy Liver parenchymal disease Portal pressure gradient

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recent advances in the diagnostic evaluation of pancreatic cystic lesions

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World Journal of Gastroenterology 2022年第6期28卷 624-634页

作者： devarshi r ardeshna Troy Cao Brandon rodgers Chidiebere Onongaya Dan Jones Wei Chen Eugene J Koay Somashekar G Krishna Department of Internal Medicine Ohio State University Wexner Medical CenterColumbusOH 43210United States College of Medicine Ohio State UniversityColumbusOH 43210United States James Molecular Laboratory Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of Pathology Ohio State University Wexner Medical CenterColumbusOH 43210United States Department of GI radiation Oncology The University of Texas MD AndersonHoustonTX77030United States Division of Gastroenterology Department of Internal MedicineOhio State University Wexner Medical CenterColumbusOH 43210United States

Pancreatic cystic lesions(PCLs)are becoming more prevalent due to more frequent abdominal imaging and the increasing age of the general *** has become crucial to identify these PCLs and subsequently risk stratify them to guide *** the high morbidity associated with pancreatic surgery,only those PCLs at high risk for malignancy should undergo such ***,current diagnostic testing is suboptimal at accurately diagnosing and risk stratifying ***,research has focused on developing new techniques for differentiating mucinous from non-mucinous PCLs and identifying high risk lesions for *** sectional imaging radiomics can potentially improve the predictive accuracy of primary risk stratification of PCLs at the time of detection to guide invasive *** cyst fluid glucose has reemerged as a potential biomarker,cyst fluid molecular markers have improved accuracy for identifying specific types of *** ultrasound guided approaches such as confocal laser endomicroscopy and through the needle microforceps biopsy have shown a good correlation with histopathological findings and are evolving techniques for identifying and risk stratifying *** most of these recent diagnostics are only practiced at selective tertiary care centers,they hold a promise that management of PCLs will only get better in the future.

关键词： Pancreatic cystic lesion Intraductal papillary mucinous neoplasms Mucinous cystic neoplasm Microforceps biopsy radiomics Confocal laser endomicroscopy

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reviving Fertility:Phytochemicals as Natural Allies in the Fight against Non-genetic Male Infertility

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Clinical Complementary Medicine and Pharmacology 2024年第1期4卷 112-128页

作者： Vivek P.Chavda Shreya S Sonak Pankti C.Balar Krupa Vyas Pranali Palandurkar Komal Mule Krishna Patel Vivek Hala Dixa A.Vaghela devarshi Acharya Akta Vaishnav Jimil Gandhi Vasso Apostolopoulos Department of Pharmaceutics and Pharmaceutical Technology L M College of PharmacyAhmedabadGujarat 380008India Bharati Vidyapeeth University’s Poona College of Pharmacy ErandwaneKothrudPune 411038India Pharmacy section L M College of PharmacyAhmedabadGujarat 380008India University Department of Pharmaceutical Sciences r.T.M Nagpur 440033India Department of Pharmaceutics Khyati College of PharmacyAhmedabad 380009India IICISST Sardar Patel UniversityVallabh Vidyanagar 388120India Institute for Health and Sport Immunology and Translational ResearchVictoria UniversityMelbourneVIC 3030Australia Immunology Program Australian Institute for Musculoskeletal ScienceMelbourneVIC 3021Australia

Background:Male infertility poses a growing challenge to the healthcare system,with its prevalence on the *** lifestyle,food,and addictions such as smoking,alcoholism,*** the *** several approaches are being investigated to prevent and treat this condition,each therapeutic approach has its *** medications continue to play a crucial role in the healthcare *** recent years,there has been a shift towards determining the efficacy of phytochemicals(or,herbal drugs)as ***:To evaluate the effect of various herbs,plant,metabolites,or a part of plant in management of non-genetic male ***:The male infertility-associated keywords were searched in PubMed,excluding those non-English writen papers.A total of 146 pertinent and closely connected records were included for full reading and inclusion in the systemic ***:The manuscript focuses on individual herbal drug components,their active ingredients,their role in improving the condition and quality of life,and decreasing the prevalence of male ***:Herbal medicinal plants show promising outcomes to treat male *** alternatives are appealing and have regained *** future holds promise for some of these herbal treatments to advance with many showing improved outcomes in males with infertility issues.

关键词： Male infertility Plant-based management Phytochemical Herbal drug Traditional Chinese medicine

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