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Actions of N-acetylcysteine,daptomycin,vancomycin,and linezolid on methicillin-resistant Staphylococcus aureus biofilms in the ventriculoperitoneal shunt infections:an experimental study

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Chinese Neurosurgical Journal 2022年第4期8卷 239-247页

作者： Tuba Kuruoglu Gamze Altun Enis Kuruoglu derya bayırlıturan Mehmet EminÖnger Department of Infectious Diseases and Clinical Microbiology Medical FacultyOndokuz Mayıs UniversitySamsunTurkey Department of Histology and Embryology Medical FacultyOndokuz Mayıs University55139 SamsunTurkey Department of Neurosurgery Medical FacultyOndokuz Mayıs UniversitySamsunTurkey Department of Infectious Diseases and Clinical Microbiology School of MedicineYeni Yuzyil UniversityIstanbulTurkey Department of Neuroscience Health Science InstituteOndokuz Mayıs UniversitySamsunTurkey

Background:Shunt systems are used to provide cerebrospinal fluid drainage in the treatment of ***,antibiotic-impregnated shunt systems are used to prevent colonization in the ventriculoperitoneal ***-resistant Staphylococcus aureus(MRSA)is the most common causative microorganism of shunt *** aim of the study is to investigate effects of several substances on MRSA biofilms in the ventriculoperitoneal ***:The present study consists of mainly eight groups(each has two subgroups as antibiotic-impregnated and nonantibiotic-impregnated catheters).In addition,each group contains six molds using MRSA *** this study,daptomycin(DAPT)(2 mg/ml),vancomycin(VAN)(10 mg/ml),linezolid(LIN)(2 mg/ml),N-acetylcysteine(NAC)(6 mg/ml),and various combinations of these substances were used to evaluate the treatment against MRSA using scanning electron microscope(SEM)images and microbiological ***:The colony count in the antibiotic-impregnated samples significantly decreased compared to nonantibiotic-impregnated samples in the MRSA,MRSA+DAPT,and MRSA+LIN groups(p<0.01),***,the colony count in antibiotic-impregnated samples significantly increased compared to nonantibiotic-impregnated samples in NAC+DAPT and NAC+VAN groups(p<0.01),***:The results showed that the use of antibiotic-impregnated catheters has a significant impact on the prevention of infection whereas the combination of NAC and DAPT showed better antibiofilm and antibacterial effects than other combinations on the prevention and treatment of nonantibiotic-impregnated catheter infections.

关键词： Methicillin-resistant Biofilm Antibiotic-impregnated catheters Scanning electron microscope

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Detecting early changes in choroidal vascularity and thickness using optical coherence tomography in patients with corneal crosslinking for keratoconus

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1267-1272页

作者： Selim Doganay Mehmet Omer Kiristioglu derya Doganay Elif Kacmaz Department of Ophthalmology Bursa Uludag University School of MedicineBursa 16059Turkey Department of Ophthalmology University of Health Sciences Bursa Yuksek Ihtisas Training and Research HospitalBursa 16310Turkey

AIM:To investigate changes in choroidal thickness and vascularity in keratoconus patients treated with corneal ***:This study evaluated 28 eyes of 22 patients with keratoconus who underwent corneal *** choroidal thicknesses were evaluated on enhanced depth imaging optical coherence tomography at the preoperative and postoperative 3d,1,and *** thickness in the four cardinal quadrants and the fovea were *** choroidal vascularity index was also ***:There was no significant difference in central choroidal thickness between the preoperative and postoperative 3d,1mo(P>0.05).There was a significant increase in the 3mo(P=0.034)and a significant decrease in the horizontal choroidal vascularity index on the postoperative 3d(P=0.014),there was no statistically significant change in vertical axes and other visits in horizontal sections(P>0.05).CONCLUSION:This study sheds light on choroidal changes in postoperative corneal crosslinking for *** it suggests the procedure’s relative safety for submacular choroid,more extensive research is necessary to confirm these findings and their clinical significance.

关键词： keratoconus corneal crosslinking choroidal vascularity index enhanced depth imaging optical coherence tomography

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Prevention of thromboembolic events after radical prostatectomy in patients with hereditary thrombophilia due to a factor V Leiden mutation by multidisciplinary coagulation management

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Asian Journal of Urology 2024年第1期11卷 42-47页

作者： Randi M.Pose Sophie Knipper Jonas Ekrutt Mara Kölker Pierre Tennstedt Hans Heinzer derya Tilki Florian Langer Markus Graefen Martini-Klinik Prostate Cancer Centre University Hospital Hamburg-EppendorfGermany Department of Urology University Hospital Hamburg-EppendorfGermany Department of Hematology and Oncology University Medical Centre Hamburg-EppendorfHamburgGermany

Objective:To examine the perioperative impact of factor V Leiden mutation on thromboembolic events'risk in radical prostatectomy(RP)*** an incidence of about 5%,factor V Leiden mutation is the most common hereditary hypercoagulability among Caucasians and rarer in *** increased risk of thromboembolic events is three-to seven-fold in heterozygous and to 80-fold in homozygous ***:Within our prospectively collected database,we analysed 33006 prostate cancer patients treated with RP between December 2001 and December *** those,patients with factor V Leiden mutation were *** patients received individualised recommendation of haemostaseologists for perioperative *** complications(deep vein thrombosis and pulmonary embolism)were assessed during hospital stay,as well as according to patient reported outcomes within the first 3 months after ***:Overall,85(0.3%)patients with known factor V Leiden mutation were *** age was 65(interquartile range:61-68)*** was at least one thrombosis in 53(62.4%)patients and 31(36.5%)patients had at least one embolic event in their medical history before *** all 85 patients with factor V Leiden mutation,we experienced no thromboembolic complications within the first 3 months after ***:In our cohort of patients with factor V Leiden mutation,no thromboembolic events were observed after RP with an individualised perioperative coagulation management *** may reassure patients with this hereditary condition who are counselled for RP.

关键词： Prostatecancer Prostatectomy Factor V Leiden mutation Thromboembolism Thrombophilia

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Corrigendum to ‘Exploring multidimensional aspects of walkability: An innovative analysis approach in Besiktas, Istanbul’ [Frontiers of Architectural Research Volume 12, Issue 6, (2023) Pages 1097–1126]

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Frontiers of Architectural Research 2024年第2期13卷 284-284页

作者： Ozge Ceylin Yildirim Asl Sungur derya Gulec Ozer Department of Architecture Yildiz Technical UniversityIstanbul 34349Turkey Department of Architecture Istanbul Technical UniversityIstanbul 34367Turkey

We thank architecture students who participated in the MIM3142 Barrier-Free Architecture course at Yildiz Technical University in 2021-2022 Spring Semester and 2022-2023Fall *** also sincerely thank Besiktas Municipality for sharing the relevant *** paper is part of a study supported by the Scientific Research Project(5159 ID)at Yildiz Technical University,*** authors would like to acknowledge that this paper is submitted in partial fulfilment of the requirements for PhD degree at YildizTechnical University.

关键词： Spring thank Pages

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Quadratic interaction effect on the dark energy density in the universe

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Chinese Physics B 2017年第10期26卷 533-538页

作者： derya G Deveci Ekrem Aydiner Department of Physics Faculty of ScienceIstanbul University Department of Opticianry Alt?nbas University

In this study, we deal with the holographic model of interacting dark components of dark energy and dark matter quadratic case of the equation of state parameter （EoS）. The effective equations of states for the interacting holographic energy density are derived and the results are analyzed and compared with the solution of the linear form in the literature. The result of our work shows that the value of interaction term between dark components affects the fixed points at far future in the DE-dominated universe in the case of quadratic EoS parameter; it is a different result from the linear case in the theoretical results in the literature, and as the Quintom scenario the equations of state had coincidence at the cosmological constant boundary of - 1 from above to below.

关键词： dark energy dark matter

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(D_(4))-Objects in Abelian Categories

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Algebra Colloquium 2022年第2期29卷 231-240页

作者： Berke Kalebogaz derya Keskin Tutuncu Department of Mathematics Hacettepe University 06800 BeytepeAnkaraTurkey

Let A be an abelian category and M∈*** M is called a(D_(4))-object if,whenever A and B are subobjects of M with M=A⊕B and f:A→B is an epimorphism,Ker f is a direct summand of *** this paper we give several equivalent conditions of(D_(4))-objects in an abelian *** other results,we prove that any object M in an abelian category A is(D_(4))if and only if for every subobject K of M such that K is the intersection K_(1)∩K_(2)of perspective direct summands K_(1)and K_(2)of M with M=K_(1)+K_(2),every morphismφ:M→M/K can be lifted to an endomorphismθ:M→M in End _(A)(M).

关键词： (D_(4))-object abelian category

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On Baer-Kaplansky Classes of Modules

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Algebra Colloquium 2017年第4期24卷 603-610页

作者： derya Keskin Tutuncu Rachid Tribak Department of Mathematics Hacettepe University 06800 Beytepe Ankara Turkey Centre Regional des Metiers de L'Education et de la Formation (CRMEF)-Tanger Avenue My Abdelaziz Souani B.P. 3117 Thngier Morocco

We are interested in studying when the class of local modules is Baer- Kaplansky. We provide an example showing that even over a commutative semisimple ring R, we can find two non-isomorphic simple R-modules S1 and S2 such that the rings EndR（S1） and EndR（S2） are isomorphic. We show that over any ring R, the class of semisimple R-modules is Baer Kaplansky if and only if so is the class of simple R-modules.

关键词： Baer Kaplansky class of modules local modules semisimple rings

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Effects of application date and rate of foliar-applied glyphosate on pine seedlings in Turkey

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Journal of Forestry Research 2018年第3期29卷 583-591页

作者： Mehmet Can Cap derya Essn Department of Forest Engineering Faculty of ForestryDüzce UniversityKonuralp Yerleskesi81620 DüzceTurkey

Glyphosate is the herbicide most extensively used for site preparation and conifer release. It is a broadspectrum herbicide and therefore crop safety is a critical issue. This study assessed the early effects of 14 different treatments, including no weed control, manual weed control, and 12 foliar-applied herbicide treatments at low,intermediate, high, and highest application rates and application timing on glyphosate phytotoxicity of containerized seedlings of Austrian pine(Pinus nigra ***.), Scots pine(P. sylvestris L.) and maritime pine(*** Aiton), conifer species widely used for afforestation and supplementary plantings in Turkish forestry. In general, Scots pine seedlings were tolerant to glyphosate compared to the other species. Glyphosate phytotoxicity varied significantly according to the time and rate of application. Seedlings were relatively tolerant to glyphosate in April whereas they were intolerant in May. The highest herbicide rate(1.2% v:v) was consistently phytotoxic to all species. Moreover, the effect of herbicide rate on seedling survival and growth varied significantly according to application date(i.e., application rate 9 date interaction). Seedlings appeared tolerant to glyphosate at low and intermediate rates(0.2, 0.4% v:v) between midspring and mid-summer, whereas they demonstrated significant sensitivity to the highest rate across all time periods. Glyphosate at the high rate(0.8% v:v) was particularly more phytotoxic when applied in May. Application of glyphosate at rates up to 0.8% could be recommended for weed control without significant pine damage in midspring when the needles presumably have a dense leaf epicuticular wax layer limiting herbicide *** of 0.8 and 1.2% v:v are not recommended during May–June.

关键词： Application date and rate Glyphosate screening Pines Seedling tolerance

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Effects of wood species and retention levels on removal of copper,chromium,and arsenic from CCA-treated wood using sodium hypochlorite

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Journal of Forestry Research 2016年第2期27卷 433-442页

作者： Engin derya Gezer Paul A.Cooper Department of Forest Industry Engineering Karadeniz Technical University61080 TrabzonTurkey Faculty of Forestry University of Toronto33 Willcocks St.TorontoON M5S 3B3Canada

Chemical extraction, bioremediation, and electrodialytic processes have been extensively studied for removal of copper, chromium, and arsenic from wood treated with chromated copper arsenate （CCA）. However, one problem has not been addressed： the effects of wood species and retention levels on remediation efficiency. The objectives of this study were to investigate the effects of wood species and retention levels on removal of copper, chromium, and arsenic from CCA-treated wood samples using sodium hypochlorite. Our results showed that sodium hypochlorite （NaOC1） was very effective for removal of copper, chromium, and arsenic from CCA-C treated milled wood samples for all three species used in this study. The Cu, Cr, and As extraction efficiencies for red pine were 95 % Cu, 97 % Cr and 94 % As, for maple were 95 % Cu, 97 % Cr, and 98 % As at 4.0 kg m-3 retention levels, and for aspen were 95 % Cu, 92% Cr, and 91% As at 9.6 kg m-3 retention level, respectively. However, the results showed that wood species and initial retention levels of CCA-treated wood products played very impor- tant roles in terms of removal of Cu, Cr, and As.

关键词： Chromated copper arsenate (CCA) Remediation Remediation efficiency Wood species Retention level

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Robotic radical prostatectomy in high-risk prostate -ancer： current perspectives

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Asian Journal of Andrology 2015年第6期17卷 908-915页

作者： Abdullah Erdem Canda Mevlana derya Balbay Yildirim Beyazit University School of MedicineAnkara Ataturk Training and Research HospitalDepartment of Urolosy Ankara Turkey Memorial Sisli Hospital Department of UrologyIstanbul Turkey.

Around 20%-30% of patients diagnosed with prostate cancer （PCa） still have high-risk PCa disease （HRPC） that requires aggressive treatment. Treatment of HRPC is controversial, and multimodality therapy combining surgery, radiation therapy, and androgen deprivation therapy have been suggested. There has been a trend toward performing radical prostatectomy （RP） in HRPC and currently, robot-assisted laparoscopic RP （RARP） has become the most common approach. Number of publications related to robotic surgery in HRPC is limited in the literature.

关键词： Robotic radical perspectives

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